检索结果-南通市图书馆

Towards understanding the ecology and mechanisms of biocontrol of Clonostachys rosea IK726

浙江大学学报(农业与生命科学版) 2004年第4期 47-47页

作者： mette Lübeck,Inge m B Knudsen,birgit Jensen,mojtaba mamarabadi,Dan Funck Jensen Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark

Clonostachys rosea (syn. Gliocladium roseum) IK726 was originally selected as an effective biocontrol agent (BCA) against cereal seed borne diseases caused by Fusarium culmorum and Bipolaris sorokiniana. We have studied the efficacy of the antagonist against different pathogens in several crops and found that the antagonist also is able to control Alternaria radicina and A. dauci on carrot seeds and different cold-storage fungi in acorns. IK726 is also able to reduce severity of soil borne Pythium spp. in cabbage, carrot and sugar beet. In addition, growth-promoting effects of IK726 have been demonstrated in barley and tomato. In order to develop and improve application methods and control strategies, essential basic studies of ecology and the mechanisms of control of IK726 is needed and has led us to use various molecular tools. The UP-PCR technology is used for strain recognition and we have developed GUS and GFP-transformants that resembles the wildtype strain in ecological fitness parameters. Using either the GUS-transformant or UP-PCR we have found that IK726, when applied with seeds, reproduces and survives several months in the rhizosphere of field grown barley and carrot. The GFP-transformant is used to study the behavior and in situ interactions of the antagonist with pathogens and plants. Using the GFP marker, we have observed conidial germination, colonization and conidiogenesis in natural soil, in vermiculite and on carrot and barley seed and roots and on barley leaves. moreover in situ interactions with Alternaria on carrot material have been studied. The modes of action of C. rosea are not well understood but enzymatic activity, mycoparasitism, substrate competition, antibiosis and induced resistance are thought to play a role. Barley treated with C. rosea IK726 has an enhanced chitinolytic and glucanolytic activity compared to the activity in non-treated barley in pot experiments with field soil. Identifi

关键词： Gliocladium roseum . biocontrol . GUS . GFP . UP-PCR . chitinase.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Towards understanding the ecology and mechanisms of biocontrol of Clonostachys rosea IK726

引用

浙江大学学报(农业与生命科学版) 2004年第4期30卷 397-397页

作者： mette Lübeck Inge m B Knudsen birgit Jensen mojtaba mamarabadi Dan Funck Jensen Department of Plant Biology Plant Pathology Section The Royal Veterinary and Agricultural University Thorvaldsensvej 40 DK-1871 Frederiksberg C. Denmark

关键词： Gliocladium roseum biocontrol GUS GFP UP-PCR chitinase.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Fault Handling in PLC-Based Industry 4.0 Automated Production Systems as a Basis for Restart and Self-Configuration and Its Evaluation

引用

Journal of Software Engineering and Applications 2016年第1期9卷 1-43页

作者： birgit Vogel-Heuser Susanne Rösch Juliane Fischer Thomas Simon Sebastian Ulewicz Jens Folmer Institute of Automation and Information Systems Technische Universitat München Munich Germany

Industry 4.0 and Cyber Physical Production Systems (CPPS) are often discussed and partially already sold. One important feature of CPPS is fault tolerance and as a consequence self-configuration and restart to increase Overall Equipment Effectiveness. To understand this challenge at first the state of the art of fault handling in industrial automated production systems (aPS) is discussed as a result of a case study analysis in eight companies developing aPS. In the next step, metrics to evaluate the concept of self-configuration and restart for aPS focusing on real-time capabilities, fault coverage and effort to increase fault coverage are proposed. Finally, two different lab size case studies prove the applicability of the concepts of self-configuration, restart and the proposed metrics.

关键词： Industry 4.0 Automated Production System OEE metrics Recovery Restart Fault Handling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一项在欧洲和中国进行的新型胃泌素释放肽前体(ProGRP)免疫检测多中心评估研究

引用

中国肺癌杂志 2017年第8期20卷 568-577页

作者： Catharina m.KORSE Stefan HOLDENRIEDER Xiuyi ZHI Xiaotong ZAHNG Ling QIU Andrea GEISTANGER marcus-Rene LISY birgit WEHNL Daan van den BROEK José m.ESCUDERO Jens STANDOP mu HU Rafael mOLINA The Netherlands Cancer Institute Plesmanlaan 121Amsterdam 1066CXThe Netherlands University Hospital Bonn and Center of Integrative Oncology Cologne/Bonn Sigmund-Freud-StrasseBonn 25-53127Germany Xuanwu Hospital Capital Medical UniversityBeijing 100053China Peking Union medical College Hospital (PUmCH) Beijing 100730China Roche Diagnostics GmbH Nonnenwald 2Penzberg 82377Germany Hospital Clinic University of BarcelonaCarrer Villarroel 170Barcelona 08036Spain

背景在欧洲和中国进行Elecsys?胃泌素释放肽前体(ProGRP)免疫检测的多中心评估研究。方法在欧洲的3个中心和中国的2个中心,在肺癌中,通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度... 详细信息

背景在欧洲和中国进行Elecsys?胃泌素释放肽前体(ProGRP)免疫检测的多中心评估研究。方法在欧洲的3个中心和中国的2个中心,在肺癌中,通过不精密度、稳定性、方法学比较和鉴别诊断能力来评价该检测法。结果 5个分析物浓度的中间不精密度范围为变异系数:2.2%-6.0%。在不同储存条件下,血浆和血清样本均显示出良好的稳定性。在血浆中Elecsys?和ARCHITECT检测(斜率1.02,截距-2.72 pg/m L)之间表现出良好的相关性。同时,Elecsys?检测在血清和血浆样本之间表现出良好的相关性(斜率0.93,截距2.35 pg/m L;相关系数0.97)。ProGRP作为不受种族、年龄、性别或吸烟史相关影响的检测手段,可鉴别小细胞和非小细胞肺癌(NSCLC);截断值为84pg/m L时,曲线下面积为0.90,95%CI:0.87-0.93;敏感性为78.3%,特异性为95%。ProGRP浓度中位数在良性病变(38pg/m L)、其他恶性肿瘤(40 pg/m L)或NSCLC(39 pg/m L)中较低,而在3期以上慢性肾脏疾病中浓度较高(>100pg/m L)。结论 Elecsys?ProGRP检测在血清和血浆中稳定性增加,较现有检测法明显更具优势。ProGRP检测在中国的首次评价在不同种族中显示出相当的鉴别能力。

关键词：鉴别诊断免疫检测促胃泌素释放肽前体 ProGRP SCLC 稳定性

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

实现ECAD与mCAD数据集成管理

引用

现代制造 2007年第33期 44-45页

作者： birgit Hagelschuer

在机器与设备制造的研发过程中,电气、控制技术和机械的结合——机电一体化,其信息系统主导未来发展。EPLAN软件与服务公司为电气和机械融合趋势提供技术支持。并且在产品数据管理中,E-CAD和m-CAD共生共长,融为一体。

关键词： CAD数据集成管理 ECAD 产品数据管理机电一体化设备制造控制技术信息系统

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Challenges for Software Engineering in Automation

引用

Journal of Software Engineering and Applications 2014年第5期7卷 440-451页

作者： birgit Vogel-Heuser Christian Diedrich Alexander Fay Sabine Jeschke Stefan Kowalewski martin Wollschlaeger Peter Gohner Institute of Automation and Information Systems Technische Universitat MünchenMünchenGermany Institute for Automation and Communication Otto von Guericke University MagdeburgMagdeburgGermany Institute of Automation Technology Helmut-Schmidt-UniversityHamburgGermany Institute of Information management in mechanical Engineering RWTH Aachen UniversityAachenGermany Computer Science 11—Embedded Software Laboratory RWTH Aachen UniversityAachenGermany Institute for Applied Computer Science Dresden University of TechnologyDresdenGermany Institute of Industrial Automation and Software Engineering University of StuttgartStuttgartGermany

This paper gives an introduction to the essential challenges of software engineering and requirements that software has to fulfill in the domain of automation. Besides, the functional characteristics, specific constraints and circumstances are considered for deriving requirements concerning usability, the technical process, the automation functions, used platform and the well-established models, which are described in detail. On the other hand, challenges result from the circumstances at different points in the single phases of the life cycle of the automated system. The requirements for life-cycle-management, tools and the changeability during runtime are described in detail.

关键词： Automation Software Engineering models Tools

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Retinal Vessels Diameter Changes during Pregnancy in Type 1 Diabetes

引用

Open Journal of Ophthalmology 2013年第2期3卷 27-32页

作者： Aurore mensah Afrouz Ahmadzadeh Ann-Sofie Svanbom Lene Ringholm birgit Sander Henrik Lund-Andersen Elisabeth mathiesen michael Larsen Department of Endocrinology Rigshospitalet Copenhagen Denmark Department of Ophthalmology Glostrup Hospital Glostrup Denmark Faculty of Health Sciences University of Copenhagen Copenhagen Denmark

Objective: Investigate how pregnancy-induced hormonal and hemodynamic changes affect retinal vessels caliber dynamic and the course of diabetic retinopathy. methods: Retinopathy grading and vessel diameter measurement using digital fundus photographs in women with diabetes type 1 taken no more than one year before conception, during week 10 and/or 22, week 34, and within one year after delivery. Calibers were measured using a custom-developed semi-automated computer algorithm which identified the six largest arteries and six largest veins and calculated the central retinal artery equivalent (CRAE) and central vein equivalent (CRVE) diameters. Glycemic control was assessed quarterly by HbA1c. Systolic and diastolic blood pressure was assessed at week 10, 22 and 34. Results: Photographs at baseline, weeks 10, 22, 34 and after delivery were available in 28 patients, of whom 24 did not progress in retinopathy. For those whose level of retinopathy remained stable CRAE constricted from 138.80 ± 21.27 μm at baseline to 129.88 ± 13.97 μm at week 10 (p = 0.0379) CRVE constricted from 195.16 ± 24.98 μm at baseline to 185.97 ± 21.96 μm at week 10 (p = 0.0400). The patients with retinopathy progression had a CRAE of 131.67 ± 13.37 μm at baseline and 132.08 ± 11.07 μm at week 10 (p = 0.34) while CRVE was 195.33 ± 24.92 μm at baseline and 204.27 ± 10.18 μm at week 10 (p = 0.16). Progressors had higher blood pressures at week 10. Conclusion: Retinal vessels constricted between prepregnancy and first trimester in women who did not experience diabetic retinopathy progression. The study suggests that the vessels constriction seen in early pregnancy contributes to reduce the risk of gestational microvascular complications and progression of diabetes in the eye.

关键词： Pregnancy and Diabetes Type 1 Diabetic Retinopathy Central Retinal Artery Equivalent Central Retinal Vein Equivalent.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Platinum-resistant ovarian cancer: Prematurely stopped phase Ⅱ Austrian AGO chemotherapy studies

引用

World Journal of Obstetrics and Gynecology 2012年第3期1卷 35-39页

作者： Edgar Petru birgit Volgger Gerhard Bogner Lukas Angleitner-Boubenizek martina Deibl Christian Schauer Alexander Reinthaller Gerhard Wolfram Alain Gustave Zeimet Christian marth Department of Obstetrics and Gynecology Medical University of Graz Department of Obstetrics and Gynecology Medical University of Innsbruckand AGO-Studienzentrale 6020 Innsbruck Austria Department of Obstetrics and Gynecology Klinikum Wels 4600 Wels Austria Department of Gynecology Hospital Barmherzige Schwestern 4020 Linz Austria Institute of Biostatistics University of Innsbruck 6020 Innsbruck Austria Department of Gynecology Hospital Barmherzige Brüder Graz 8020 Graz Austria Department of Obstetrics and Gynecology Medical University of Vienna 1090 Vienna Austria Department of Gynecology Hospital Barmherzige Schwestern 4910 Ried Austria Department of Obstetrics and Gynecology Medical University of Innsbruck 6020 Innsbruck Austria

AIm： To report the results of two phase Ⅱ studies of chemotherapy in patients with platinum-resistant and platinum-refractory ovarian cancer and discuss the cur-rent status of systemic therapy in this ***： Two subsequent Austrian Arbeitsgemein-schaft für Gynkologische Onkologie （AGO） phase Ⅱ studies have been carried out. Patients either had platinum-refractory or platinum-resistant disease, i.e., disease progression during first line platinum-based therapy or recurrence within 6 mo following the last platinum-containing chemotherapy, respectively. In the first study, 6 cycles of irinotecan at 55 mg/m2 and docetaxel 25 mg/m2 were both administered on days 1, 8 and 15 of a 4 wk cycle. In the second phase Ⅱ study, either non-pegylated （PEG） liposomal doxorubi-cin （L-DXR） 60 mg/m2 monotherapy on day 1 and PEG filgrastim on day 2 （arm A） or L-DXR at 50 mg/m2 and gemcitabine （GEm） at 650 mg/m2 on day 1 and GEm on day 8 （arm B） were administered every 4 wk. Patients in arm B received prophylactic filgrastim 5 μg/kg per day from days 3 to 6 and from days 9 to 12, respec-tively. RESULTS： Response rates in studies were 14% and 17%, respectively. The progression-free survival was less than 3 mo. Diarrhea was most prevalent in patients treated with irinotecan ＋ docetaxel, while stomatitis/mucositis occurred in a quarter of patients treated with L-DXR ＋/- GEm ＋ granulocyte colony stimulating factor, respectively. Following treatment with the latter regi-men, a total of 11 serious adverse events were record-ed among the 12 patients included. The rate of remis-sions of the regimens used in these two Austrian AGOstudies was low and their toxicity significant. Due to their low therapeutic index, neither of these regimens can be recommended in this heavily pretreated patient population with platinum-resistant ovarian cancer ex-hibiting a high tumor-associated symptom burden. CONCLUSION： The two reported phase Ⅱ studies of the Austrian AGO in platinum-resistant disease ha

关键词： Platinum-resistance Ovarian cancer Chemotherapy Gemcitabine Non-pegylated liposomadoxorubicin Irinotecan Docetaxel

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

塔里木河下游阿拉干断面胡杨树高的分布和密度

引用

生态环境 2008年第3期17卷 1086-1090页

作者：蔡富艳玉米提·哈力克艾尔肯·艾白不拉阿布都米吉提·阿布力克木 Bodo Coenradie birgit Kleinschmit 新疆大学资源与环境科学学院新疆乌鲁木齐830046 新疆绿洲生态教育部重点实验室新疆乌鲁木齐830046 塔里木河流域管理局新疆库尔勒841000 中国科学院新疆生态与地理研究所新疆乌鲁木齐830011 德国柏林理工大学景观规划研究所德国柏林10623

通过小尺度生态监测与遥感数据分析获取塔里木河下游胡杨（Populus euphratica Oliv．）林现状信息，将胡杨个体对输水的响应实测数据和QuickBird影像信息进行对比和分析，“面”上宏观调查与“点”上典型研究相结合，集中对塔里木河下... 详细信息

通过小尺度生态监测与遥感数据分析获取塔里木河下游胡杨（Populus euphratica Oliv．）林现状信息，将胡杨个体对输水的响应实测数据和QuickBird影像信息进行对比和分析，“面”上宏观调查与“点”上典型研究相结合，集中对塔里木河下游阿拉干断面设立的100hm2长期监洲样方内的4500棵胡杨树进行了详细的调查。研究表明：胡杨密度随着离河岸距离增加而呈现降低的规律。不同树高的胡杨也呈一定规律分布。树高小于3m的幼树主要分布在距河道50m范围内；树高3-9m之间的胡杨在研究区中占绝对优势；树高大于9m的胡杨在距河道200m内分布比较均匀，200m之外分布稀少。

关键词：塔里木河下游生态输水胡杨树高密度结构

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

越南河内国家会议中心(NCC)

引用

建筑技艺 2010年第7期16卷 40-47页

作者：曼哈德.冯.格康 Susi Winter Tuyen Tran Viet Robert Wildegger Hito Ueda marcus Tanzen Udo meyer birgit Fllmer Jens Reichert Uli Rsler Frederik Heisel Annika Schrder Elena melnikova markus Carlsen Nicole Flores Schlotfeldt Licht müller BBm Breimann Bruun Christian Gahl 德国gmp建筑师事务所越南国家建设咨询公司

会议中心、酒店和博物馆镶嵌在一片以越南文化和传统作为特色主题和象征的开阔的景观园林内。会议中心作为主导建筑坐落于南北轴线上,几乎占据了以大湖、小池和假山为特色的整个景观公园的中心地带。与园林景观的有机形状形成鲜明对比... 详细信息

会议中心、酒店和博物馆镶嵌在一片以越南文化和传统作为特色主题和象征的开阔的景观园林内。会议中心作为主导建筑坐落于南北轴线上,几乎占据了以大湖、小池和假山为特色的整个景观公园的中心地带。与园林景观的有机形状形成鲜明对比的是：道路和步道系统规划为一个严密的线性网格。

关键词：南河景观园林中心地带园林景观博物馆酒店建筑公园

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：