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First total synthesis of (±)-malaysianone A and (±)-tanariflavanones B

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Chinese Chemical Letters 2013年第11期24卷 1027-1029页

作者： Jin-Hui Yang bing-bing chen Yi-Min Xie Yao Feng Xiao-Qin Ma State Key Laboratory Cultivation Base of Natural Gas Conversion Ningxia University

A concise approach for the frst total synthesis of two naturally occurring flavanoids,（）-malaysianone A（1）and（）-tanariflavanones B（2）,has been accomplished with total yields of 12.9%and 10.4%,*** key steps were regioselective deprotection and regioselective synthesis of 5-formaldehyde-8-hydroxy-2-[40-methyl-30-penteneyl]-dihydro-1-benzopyran（8）.

关键词： Malaysianone A Tanariflavanones B Total synthesis Flavanoids

Toward Artificial Peptide Nanocapsules

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Nano-Micro Letters 2024年第10期16卷 240-243页

作者： Yuan Wang bing chen Laboratory for Biomaterials and Drug Delivery Department of AnesthesiologyDivision of Critical Care MedicineBoston Children's HospitalHarvard Medical SchoolBostonMA 02115USA College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023People's Republic of China

HIGHLIGHTS The formation of peptide nanocapsules is facilitated by a gradient interface,where the differential solvent concentration drives the peptides to preferentially localize and *** peptide nanocapsules,characterized by their hollow structures,demonstrated potential as carriers for targeted drug delivery.1 Introduction Peptide nanocapsules are a type of nanoscale delivery system that encapsulates active substances within a shell composed of peptides,leveraging the unique properties of peptides such as biocompatibility and biodegradability[1].Historically,the development of peptide nanocapsules was inspired primordially by the natural biological processes.

关键词： Peptide nanocapsules Self-assembly Drug delivery Nanomedicine

Effects of radix curcumae-derived diterpenoid C on Helicobacter pylori-induced inflammation and nuclear factor kappa B signal pathways

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World Journal of Gastroenterology 2013年第31期19卷 5085-5093页

作者： Xuan Huang Bin Lv Shuo Zhang Qun Dai bing-bing chen Li-Na Meng Department of Gastroenterology the First Affiliated Hospital Zhejiang Chinese Medical University

AIM:To study effect of diterpenoid C extracted from radix curcumae on Helicobacter pylori(***)-infected inflammation,intestinal metaplasia,and nuclear factor kappa B(NF-κB)signaling pathway in ***:We used I-type *** to infect human gastric epithelial gastric epithelium cell line(GES-1)cell lines,and then ***-infected GES-1 cells were treated with radix curcumae(RC)-derived diterpenoid C of different concentrations(5,10,20μg/mL)and *** expression of p65,IκB kinase(IKK)αand IKKγproteins was detected with Western blotting,and the expression of interleukin(IL)-8,IL-6 and IL-4 was determined with enzyme-linked immunosorbent assay *** were analyzed using SPSS software *** comparisons between groups of more than two unpaired values,one-way analysis of variance(ANOVA)was *** an ANOVA F value was significant,post hoc comparisons were performed between *** results were not normally distributed,the Mann-Whitney U test was used to compare two groups of unpaired values,whereas for comparisons between groups of more than two unpaired values,the Kruskal-Wallis H test was *** significance was established at P<***:The MTT assay results revealed the inhibited rate of GES-1,and indicated that the IC5 of RCderived diterpenoid C and amoxicillin all were 5μg/mL for gastric GES-1 *** expression of IL-8 was significantly increased,especially at 12 h time point;and the expression of IL-4 was decreased in *** GES-1 *** ***-infected GES-1 cells were treated with RC-derived diterpenoid C of different concentrations and amoxicillin,the expression of IL-8was decreased at 12,24,48,72 h points(P<0.01),especially in high-concentration diterpenoid C(20μg/mL)group;and the expression of IL-4 was increased,especially in moderate and high-concentration diterpenoid C(10 and 20μg/mL)***-derived diterpenoid C had the inhibitory effects on ***-induced p65 translocation from cytopla

关键词： Radix curcumae-derived diterpenoid C Helicobacter pylori Nuclear factor-κB Inflammatory cytokine

2D all-organic perovskites refine flexible electronics

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Science China Materials 2024年第7期67卷 2365-2366页

作者： Wei Zhou bing chen College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China

Recent years have witnessed a paradigm shift with the advent of perovskites,a class of materials with a distinct CaTiO_(3)-type crystalline structure that show remarkable promise across a wide array of applications,including photovoltaics,photodetectors,lighting,lasers,and so *** them,the development of two-dimensional(2D)perovskites has garnered significant attention due to their tunable structures(mainly Dion-Jacobson and Ruddlesden-Popper structures)and enhanced stability in comparison with their 3D counterparts[1].Amidst the burgeoning research on perovskites,on the other side,all-organic perovskites stand out as a particularly intriguing subset[2].Unlike traditional perovskites that typically comprise all-inorganic(e.g.,CsPbBr_(3))or organic-inorganic hybrid components(e.g.,(PEA)_(2)PbI_(4)),all-organic perovskites are composed entirely of carbon-or nitrogen-based molecules.

关键词： perovskite inorganic entirely

Multimodal fusion recognition for digital twin

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Digital Communications and Networks 2024年第2期10卷 337-346页

作者： Tianzhe Zhou Xuguang Zhang bing Kang Mingkai chen Key Laboratory of Broadband Wireless Communication and Sensor Network Technology Ministry of EducationNanjing University of Posts and TelecommunicationsNanjing210003China

The digital twin is the concept of transcending reality,which is the reverse feedback from the real physical space to the virtual digital *** hold great prospects for this emerging *** order to realize the upgrading of the digital twin industrial chain,it is urgent to introduce more modalities,such as vision,haptics,hearing and smell,into the virtual digital space,which assists physical entities and virtual objects in creating a closer ***,perceptual understanding and object recognition have become an urgent hot topic in the digital *** surface material classification schemes often achieve recognition through machine learning or deep learning in a single modality,ignoring the complementarity between multiple *** order to overcome this dilemma,we propose a multimodal fusion network in our article that combines two modalities,visual and haptic,for surface material *** the one hand,the network makes full use of the potential correlations between multiple modalities to deeply mine the modal semantics and complete the data *** the other hand,the network is extensible and can be used as a universal architecture to include more *** show that the constructed multimodal fusion network can achieve 99.42%classification accuracy while reducing complexity.

关键词： Digital twin Multimodal fusion Object recognition Deep learning Transfer learning

Effects of physical crust on soil detachment by overland flow in the Loess Plateau region of China

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International Soil and Water Conservation Research 2024年第1期12卷 107-120页

作者： Jiaxin Liu Liding chen bing Wang Xiaoyu Peng School of Ecology and Environmental Science Yunnan UniversityKunming650091China State Key Laboratory of Soil Erosion and Dryland Farming on the Loess Plateau Institute of Soil and Water ConservationNorthwest A&F UniversityYanglingShaanxi712100China University of Chinese Academy of Sciences Beijing100049China

Physical soil crust(PSC),a key component of surface soil structure,exists extensively in loess *** is considered to have a significant effect on soil detachment ***,the long-term effects and the corresponding mechanisms of PSC on soil detachment by overland flow are still not well understood,especially in natural *** investigate temporal variation in soil erosion resistance and the underlying factors during PSC formation,an 8×8-m soil plot was exposed to natural conditions in the Loess Plateau over a 524-day period spanning two rainy seasons and a winter between them.A flume test was conducted to determine soil detachment capacity(Dc)under six designed flow shear stress levels(5.66-22.11 Pa)using crusted(SC)and non-crusted(NSC)soil samples at different PSC development ***,two soil erosion resistance parameters,rill erodibility(K_(r))and critical shear stress(τ_(c)),were *** time,in the SC and NSC treatments,K_(r)decreased from 0.516 to 0.120 s m^(-1)and 0.521 to 0.223 s m^(-1),respectively,whileτ_(c)increased from 0.49 to 4.42 Pa and 0.26-2.46 Pa,*** in soil erosion resistance was rapid in the first one to two months,and then slowed down,with slight fluctuations *** the SC treatment,K_(r)was 42%lower andτ_(c)was 67%greater than those in the NSC *** properties changed greatly for both *** increased from 0 to 7.09 mm in the SC *** increased from 2.91 to 9.04 kPa and 3.01-4.78 kPa in SC and NSC treatments,*** soil erosion resistance parameters could be well predicted by SCT and Coh in the SC treatment(R^(2)≥0.82),while their best predictor was Coh in the NSC treatment(R^(2)≥0.90).The results demonstrate that PSC formation enhances soil erosion resistance in the soil detachment process in the loess region under natural *** study revealed the important role and complexity of PSC in the process of soil erosion,and provided theor

关键词： Physical soil crust formation Soil heterogeneity Rill erodibility Critical shear stress

Development of a novel Eu^(3+)-doped tantalate red-emitting phosphor for w-LEDs application

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Journal of Rare Earths 2024年第8期42卷 1479-1488,I0003页

作者： Fan Zeng Jingjing Ru bing Zhao Feiyun Guo Jianzhong chen College of Chemistry and Materials Fujian Province University Key Laboratory of Green Energy and Environment CatalysisNingde Normal University.Ningde352100China School of Environment and Resources School of Carbon Neutral and Modern IndustryFujian Normal UniversityFuzhou350007China College of Information and Mechanical&Electrical Engineering Ningde Normal UniversityNingde352100China College of Chemistry Fuzhou UniversityFuzhou350108China

Two novel phosphors LiBa_(4(1-x))Eu_(4x)Ta_(3)O_(12)(H-LBTO:xEu^(3+)) and Li_(0.25)Ba_(1-x)Eu_(x)Ta_(0.75)O_(3)(C-LBTO:xEu^(3+))were prepared successfully by a molten salt *** transformation between these two structures was realized by changing the sintering temperature or changing the Eu^(3+) ions concentration,which was also demonstrated by the X-ray diffraction(XRD),scanning electron microscopy(SEM),diffuse reflectance spectra(DRS),and photoluminescence excitation(PLE) analyses,Both the sintering temperature and the Eu^(3+)ions doping concentration have significant impact on the formation of the crystal *** these phosphors sintered at 1023 K exhibit two major luminescence lines at 594 and 614 nm under nearUV light of 395 nm excitation,corresponding to Eu^(3+)ions typical transitions of ^(5)D_(0)→^(7)F_(1) and ^(5)D_(0)→^(7)F_(2).The optimum concentration of Eu^(3+) ions is 9 mol% for C-LBTO:xEu^(3+) samples and the quenching interaction type is the nearest-neighbor ion *** thermal stability of the C-LBTO:0.09Eu^(3+)sample was investigated in detail and the device application further suggests that C-LBTO:0.09Eu^(3+) can be used as a red phosphor for near-UV excited w-LEDs in lighting.

关键词： Phosphor Tantalate LED device Rare earths

Optimal SOC Headroom of Pump Storage Hydropower for Maximizing Joint Revenue from Day-ahead and Real-time Markets Under Regional Transmission Organization Dispatch

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Journal of Modern Power Systems and Clean Energy 2024年第1期12卷 238-250页

作者： Yikui Liu bing Huang Yang Lin Yonghong chen Lei Wu Electrical and Computer Engineering Department Stevens Institute of TechnologyHobokenNJ 07030USA Midcontinent Independent System Operator Inc.CarmelIN 46032USA

In response to the increasing penetration of volatile and uncertain renewable energy,the regional transmission organizations(RTOs)have been recently focusing on enhancing the models of pump storage hydropower(PSH)plants,which are one of the key flexibility assets in the day-ahead(DA)and real-time(RT)markets,to further boost their flexibility provision *** by the recent research works that explored the potential benefits of excluding PSHs’cost-related terms from the objective functions of the DA market clearing model,this paper completes a rolling RT market scheme that is compatible with the DA ***,with the vision that PSHs could be permitted to submit state-of-charge(SOC)headrooms in the DA market and to release them in the RT market,this paper uncovers that PSHs could increase the total revenues from the two markets by optimizing their SOC headrooms,assisted by the proposed tri-level optimal SOC headroom ***,in the proposed tri-level model,the middle and lower levels respectively mimic the DA and RT scheduling processes of PSHs,and the upper level determines the optimal headrooms to be submitted to the RTO for maximizing the total revenue from the two *** case studies quantify the profitability of the optimal SOC headroom submissions as well as the associated financial risks.

关键词： Pump storage hydropower energy market state-of-charge(SOC) headroom market revenue tri-level problem

A non-probabilistic reliability topology optimization method based on aggregation function and matrix multiplication considering buckling response constraints

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Applied Mathematics and Mechanics(English Edition) 2024年第2期45卷 321-336页

作者： Lei WANG Yingge LIU Juxi HU Weimin chen bing HAN Institute of Solid Mechanics School of Aeronautic Science and EngineeringBeihang UniversityBeijing 100191China Aircraft and Propulsion Laboratory Ningbo Institute of TechnologyBeihang UniversityNingbo 315100Zhejiang ProvinceChina State Key Laboratory of Navigation and Safety Technology Shanghai Ship and Shipping Research InstituteShanghai 200135China National Engineering Research Center of Ship&Shipping Control System Shanghai Ship and Shipping Research InstituteShanghai 200135China

A non-probabilistic reliability topology optimization method is proposed based on the aggregation function and matrix *** expression of the geometric stiffness matrix is derived,the finite element linear buckling analysis is conducted,and the sensitivity solution of the linear buckling factor is *** a specific problem in linear buckling topology optimization,a Heaviside projection function based on the exponential smooth growth is developed to eliminate the gray *** aggregation function method is used to consider the high-order eigenvalues,so as to obtain continuous sensitivity information and refined structural *** cyclic matrix programming,a fast topology optimization method that can be used to efficiently obtain the unit assembly and sensitivity solution is *** maximize the buckling load,under the constraint of the given buckling load,two types of topological optimization columns are *** variable density method is used to achieve the topology optimization solution along with the moving asymptote optimization *** vertex method and the matching point method are used to carry out an uncertainty propagation analysis,and the non-probability reliability topology optimization method considering buckling responses is developed based on the transformation of non-probability reliability indices based on the characteristic ***,the differences in the structural topology optimization under different reliability degrees are illustrated by examples.

关键词： buckling topology optimization aggregation function uncertainty propagation analysis non-probabilistic reliability