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ADAM10对小鼠颅颌面膜内成骨的影响

组织工程与重建外科杂志 2017年第1期13卷 13-16,39页

作者：谭宇罗薇曹海峰房兵杨秩上海市上海交通大学医学院附属第九人民医院口腔第二门诊部 201900 上海市上海市口腔病防治院口腔正畸科 200001 上海市上海交通大学医学院附属第九人民医院口腔颅颌面科正颌正畸中心 200011

目的探索解聚素样金属蛋白酶10(ADAM10)对小鼠颅颌面骨骼膜内成骨的影响。方法应用组织免疫荧光染色及蛋白免疫印迹研究ADAM10在小鼠颅颌面骨中的不同时间点、不同部位的表达水平。通过cre-loxp技术在胚胎小鼠颅颌面骨骼中特异性敲除ADA... 详细信息

目的探索解聚素样金属蛋白酶10(ADAM10)对小鼠颅颌面骨骼膜内成骨的影响。方法应用组织免疫荧光染色及蛋白免疫印迹研究ADAM10在小鼠颅颌面骨中的不同时间点、不同部位的表达水平。通过cre-loxp技术在胚胎小鼠颅颌面骨骼中特异性敲除ADAM10基因,应用体视显微镜观察基因敲除小鼠的颅颌面畸形,X线检查、von Kossa染色检测基因敲除小鼠骨钙化情况,双标免疫荧光观察基因敲除小鼠骨组织细胞增殖、分化、凋亡能力的改变。结果组织免疫荧光染色显示小鼠上、下颌骨成骨活跃区ADAM10表达明显,同时蛋白免疫印迹结果证实,ADAM10在小鼠出生前后表达高,成年后表达明显降低。大体观察基因敲除小鼠身体体型较小,颅颌面畸形表现为面中部发育不足,上下颌骨发育不足,颅顶塌陷。X线片检测及von Kosaa染色显示基因敲除小鼠全身骨骼密度减低,骨组织形成较弱。免疫荧光检测发现ADAM10基因敲除小鼠下颌骨细胞增殖、成骨分化能力减低、凋亡增加。结论 ADAM10广泛表达于小鼠膜内成骨区域,可能通过影响骨组织细胞增殖、分化及凋亡来调控小鼠颅面部膜内成骨过程。

关键词：解聚素样金属蛋白酶10 颅颌面骨骼膜内成骨

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基于线性规划的抹茶智能拼配研究

贵州科学 2020年第5期38卷 80-84页

作者：于杰王雅洁杨冰张成梅陈恺贵州省分析测试研究院贵州贵阳550000

主要研究一种基于线性规划的抹茶智能拼配算法模型,旨在解决传统人工拼配方式存在的效率低下、茶叶产品品质不佳等问题。充分考虑企业投入成本、原料多产地、库存陈原料使用率、气候及海拔等多种因素,详细阐述了智能拼配算法模型和约束... 详细信息

主要研究一种基于线性规划的抹茶智能拼配算法模型,旨在解决传统人工拼配方式存在的效率低下、茶叶产品品质不佳等问题。充分考虑企业投入成本、原料多产地、库存陈原料使用率、气候及海拔等多种因素,详细阐述了智能拼配算法模型和约束条件的构成及其关联关系,以实现企业投入成本最低为目标,对各种抹茶待拼原料的拼配比例及最小投入成本进行求解,自动计算生成抹茶拼配配方,为企业提供了一个高效、成本可控的抹茶拼配方案,并将研究成果成功运用于某大型茶厂。

关键词：线性规划智能拼配约束条件关联关系最小投入成本

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利用电镀污泥的生物淋滤液制备锰锌铁氧体

应用化工 2022年第6期51卷 1540-1547页

作者：李志华田炳阳崔延超赵伟旭温灵凯王佳辛宝平北京理工大学材料学院北京100081

对吉林某厂产生的4种电镀污泥(1#、2#、3#、4#)进行预处理、消解、BCR连续萃取、XRD、SEM、TEM的分析表征,确定目标金属均为Mn、Ni、Cu、Zn、Co。将4种污泥按质量比等量混匀后生物淋滤。在非接触生物淋滤下的最优浸出条件为:初始pH=1.0... 详细信息

对吉林某厂产生的4种电镀污泥(1#、2#、3#、4#)进行预处理、消解、BCR连续萃取、XRD、SEM、TEM的分析表征,确定目标金属均为Mn、Ni、Cu、Zn、Co。将4种污泥按质量比等量混匀后生物淋滤。在非接触生物淋滤下的最优浸出条件为:初始pH=1.0,固液比10%,转速120 r/min,在该条件下,Mn、Ni、Cu、Zn均能100%浸出。收集生物淋滤液,以氨水作沉淀剂,利用水热法将淋滤液中的金属离子制备成了立方形,球形,颗粒大小均一,尺寸10~30 nm左右,饱和磁化强度60.115 emu/g的高性能Mn_(0.6)Zn_(0.4)Fe_(2)O_(4)软磁材料。

关键词：电镀污泥生物淋滤循环富集锰锌铁氧体

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Reusing Service Process Fragments with a Consensus Between Service Providers and Users

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Chinese Journal of Electronics 2016年第4期25卷 648-657页

作者： yang Rong LI bing WANG Jian LI Zengyang HU Yan College of Computer Science and Technology Hubei University of Science and Technology International School of Software Wuhan University State Key Laboratory of Software Engineering & School of Computer Wuhan University Science and Technology on Integrated Information System Laboratory Institute of SoftwareUniversity of Chinese Academy of Sciences

Recent years have witnessed a rapid growth in using Web services for data publishing and sharing among *** improve the efficiency of software development and economize on human and material resources,service reuse is viewed as a powerful means which will not only reuse atomic services,but also reuse arbitrary granularities of Service process fragments(SPFs).However,effectively reusing arbitrary granularities of SPFs has not been solved yet,let alone taking diverse Qo S preferences of service providers and users into *** this paper,we propose a novel method of SPF reuse,named SCKY,based on the Cocke-Kasami-Younger(CKY) *** first present an extended CKY to do *** we address how to do SPF-query by a probability CKY,i.e.,return a SPF with maximum emergence ***,we explore the SPF-query with a consensus of Qo S preferences between service providers and *** a set of experiments,the effectiveness and robustness of our approach are evaluated.

关键词： Cocke-Kasami-Younger algorithm Service reuse Service process fragment Qo S preferences

Strength and deformation behaviors of bedded rock mass under bolt reinforcement

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International Journal of Mining Science and Technology 2018年第4期28卷 591-597页

作者： Wenxin Zhu Hongwen Jing Lijun yang bing Pan Haijian Su State Key Laboratory for Geomechanics and Deep Underground Engineering China University of Mining and Technology School of Traffic and Civil Engineering Shandong Jiaotong University

The mechanism of bolt support is an important topic in mining engineering and slope treatment. The artificial material and loading system were self-developed to study the influence of bedding cohesion and bolt number on the anchoring behavior of bedded rock mass. The results show that, both peak strength and elasticity modulus increase gradually with the increase of bedding cohesion and bolt number. The axial stress–strain curve of bedded rock mass under the reinforcement of bolts presents the features of strain-softening and secondary strengthening. Finally, anchoring behavior of bedded rock mass with different bolt numbers was simulated by using FLAC3 D numerical program and the results were compared with the experimental results. This study can provide certain bases to the stability control and support design of bedded rock mass in roadway.

关键词： Bedded rock mass Anchoring behavior Peak strength Bedding cohesion Secondary strengthening

Towards optimal recovery scheduling for dynamic resilience of networked infrastructure

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Journal of Systems Engineering and Electronics 2018年第5期29卷 995-1008页

作者： WANG yang FU Shanshan WU bing HUANG Jinhui WEI Xiaoyang Intelligent Transportation System Research Center Wuhan University of Technology College of Ocean Science and Engineering Shanghai Maritime University Department of Civil and Environmental Engineering National University of Singapore

Prior research on the resilience of critical infrastructure usually utilizes the network model to characterize the structure of the components so that a quantitative representation of resilience can be obtained. Particularly, network component importance is addressed to express its significance in shaping the resilience performance of the whole system. Due to the intrinsic complexity of the problem, some idealized assumptions are exerted on the resilience-optimization problem to find partial solutions. This paper seeks to exploit the dynamic aspect of system resilience, i.e., the scheduling problem of link recovery in the post-disruption *** aim is to analyze the recovery strategy of the system with more practical assumptions, especially inhomogeneous time cost among links. In view of this, the presented work translates the resilience-maximization recovery plan into the dynamic decisionmaking of runtime recovery option. A heuristic scheme is devised to treat the core problem of link selection in an ongoing *** Monte Carlo simulation, the link recovery order rendered by the proposed scheme demonstrates excellent resilience performance as well as accommodation with uncertainty caused by epistemic knowledge.

关键词： dynamic resilience network model component importance recovery scheduling epistemic uncertainty

Advances in self-assembly-based circularly polarized luminescent materials

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Science China Chemistry 2024年第10期67卷 3247-3257页

作者： bing-Hao Liu yang Zong Na Liu Zong-Quan Wu State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchun 130012China The School of Pharmaceutical Sciences Jilin UniversityChangchun 130021China

Circularly polarized luminescent(CPL)materials have garnered attention for their diverse applications,including three-dimensional(3D)imaging,bio-imaging,chiral sensing,and other emerging ***,the fabrication of CPL-activated materials required the use of chiral luminescent small *** introduction of the idea of self-assembly has transformed the production of CPL-activated materials,providing new and promising opportunities for their *** utilizing self-assembly,it is now feasible to produce chiral nano-assemblies with CPL activity not only from chiral molecules but also from non-chiral substances and inorganic *** addition,self-assembly routes provide a way to increase the asymmetry factor,creating possibilities for additional refinement and adjustment of CPL material *** review offers a summary of the current progress and developments in the self-assembly of small molecules and polymers,with a specific emphasis on their capacity to create or enhance CPL in different *** aim of this review is to inspire interest in optical materials that are based on the principles of self-assembly.

关键词： circularly polarized luminescence photochemistry self-assembly chiral materials

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BaF_2微晶的γ辐照缺陷

物理学报 1995年第8期44卷 1296-1301页

作者：侯碧辉陆肖璞施朝淑侯碧辉杨炳忻中国科学技术大学物理系合肥230026 中国科学技术大学结构分析开放研究实验室合肥230026 中国科学技术大学近代物理系合肥230026

用电子自旋共振(ESR)方法研究BaF_2微晶和单晶研粉的γ射线辐照损伤及其恢复情况,发现V_k心点缺陷的ESR信号随升温变化不象H,F和M心那样是单调衰减的,γ射线辐照可能会激发F^-离子上的Frendkel激子,该激子受热湮没而产生新的V_k心,因而... 详细信息

用电子自旋共振(ESR)方法研究BaF_2微晶和单晶研粉的γ射线辐照损伤及其恢复情况,发现V_k心点缺陷的ESR信号随升温变化不象H,F和M心那样是单调衰减的,γ射线辐照可能会激发F^-离子上的Frendkel激子,该激子受热湮没而产生新的V_k心,因而使V_k心的ESR信号随开温增强,V_t心的朗德因子g也随升温而变化.单晶研粉的辐照损伤在400℃完全恢复,微晶的在355℃完全恢复.

关键词：二氟化钡微晶 γ辐照损伤

Synthesis of Mono-fluoroallenes through Copper-Catalyzed Defluorinative Silylation of α,α-Difluoroalkylalkynes

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Chinese Journal of Chemistry 2022年第17期40卷 2035-2039页

作者： Luning Tang bing-bing Pei yang Song Fei Xue Yanni Yue Chao Feng Technical Institute of Fluorochemistry(TIF) Institute of Advanced Synthesis(IAS)School of Chemistry and Molecular EngineeringNanjing Tech UniversityNanjingJiangsu211816 China Institute of Material Physics&Chemistry College of ScienceNanjing Forestry UniversityNanjingJiangsu210037 China

A straightforward protocol for the synthesis of mono-fluorinated allenes via catalytic defluorinative silylation of the readily availableα,α-difluoroalkylalkynes with commercially available copper catalyst and phosphine ligand is described.A broad scope ofα,α-difluoroalkylalkynes were well accommodated and a gram-scale synthesis demonstrated the synthetic utility of this methodoglogy.

关键词： Allenes Copper Defluorination Silylation α,α-Difluoroalkylalkyne