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Are allometric model parameters of aboveground biomass for trees phylogenetically constrained?

Plant Diversity 2023年第2期45卷 229-233页

作者： Xing-Zhao Huang fang-bing Li Zi-Xuan Wang Yi Jin Hong Qian School of Forestry&Landscape of Architecture Anhui Agricultural UniversityHefei 230036China State Key Laboratory of Vegetation and Environmental Change Institute of BotanyChinese Academy of SciencesBeijing 100093China Key Laboratory of National Forestry and Grassland Administration on Biodiversity Conservation in Karst Mountainous Areas of Southwestern China Guizhou Normal UniversityGuiyang 550025China Research and Collections Center Illinois State Museum1011 East Ash StreetSpringfieldIL 62703USA

Knowledge of which biological and functional traits have,or lack,phylogenetic signal in a particular group of organisms is important to understanding the formation and functioning of biological *** biomass models reflecting tree growth characteristics are commonly used to predict forest ***,few studies have examined whether model parameters are constrained by ***,we use a comprehensive database(including 276 tree species) compiled from 894 allometric biomass models published in 302 articles to examine whether parameters a and b of the model W=aD~b(where W stands for aboveground biomass,D is diameter at breast height) exhibit phylogenetic signal for all tree species as a whole and for different groups of tree *** either model parameter,we relate difference in model parameter between different tree species to phylogenetic distance and to environmental distance between pairwise *** study shows that neither model parameter exhibits phylogenetic signals(Pagel's λ and Blomberg's K both approach zero).This is the case regardless of whether all tree species in our data set were analyzed as a whole or tree species in different taxonomic groups(gymnosperm and angiosperm),leaf duration groups(evergreen and deciduous),or ecological groups(tropical,temperate and boreal) were analyzed *** study also shows that difference in each parameter of the allometric biomass model is not significantly related to phylogenetic and environmental distances between tree species in different sites.

关键词： Allometric biomass model Pagel'sλ Blomberg's K Phylogenetic constraint

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Protection of Carassius auratus Gibelio against infection by Aeromonas hydrophila using specific immunoglobulins from hen egg yolk

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2006年第11期7卷 922-928页

作者： LI Xiao-liang SHUAI Jiang-bing fang Wei-huan Institute of Preventive Veterinary Medicine and Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine Zhejiang University Hangzhou 310029 China

Specific immunoglobulin (IgY) from egg yolk against Aeromonas hydrophila was produced by immunization of White Leghorn hens with formalin-killed whole cells of A. hydrophila. ELISA test using A. hydrophila as the coating antigen revealed that the specific antibody titer started to increase in the egg yolk at the 13th day post-immunization (P/N=2.18), reached the peak at the 56th day (P/N=13.82), and remained at high level until day 133 (P/N=7.03). The antibody was purified by saturated ammonium sulphate with a recovery rate of 63.5%. The specific IgY inhibited the growth of A. hydrophila at a concentration of 1.0 mg/ml during the 18 h incubation. Pre-treatment of polyploid gibel carps Carassius auratus Gibelio with specific IgY had a protection rate of 60% (6/10) against challenge with A. hydrophila, while none of the fishes in the control groups receiving sterile phosphate buffered saline (PBS) or non-specific IgY survived the challenge. Treatment of fishes with the specific IgY 4 h after the challenge also had lower mortality (70%, 7/10), a 30% reduction against the control PBS or non-specific IgY groups (10/10). These results indicate that specific IgY antibodies could be obtained easily from hens immunized with an inactivated A. hydrophila and could provide a novel alternative approach to control of diseases in fishes caused by this organism.

关键词： Aeromonas hydrophila Immunoglobulins Hen egg yolk Polyploid gibel carps Carassius auratus Gibelio

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面向不同训练内容的训练环境快速切换方法

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指挥信息系统与技术 2024年第1期15卷 35-39页

作者：方冰付建苏王政伟张民强中国电子科技集团公司第二十八研究所南京210023

训练环境中,传统的人工部署和配置切换方式效率低且易出错,不利于用户在不同训练对象和训练模式下对训练的灵活组织与应用。为满足当前训练需求,提出了一种面向不同训练内容的训练环境快速切换方法。首先,阐述了该方法的主要原理;然后,... 详细信息

训练环境中,传统的人工部署和配置切换方式效率低且易出错,不利于用户在不同训练对象和训练模式下对训练的灵活组织与应用。为满足当前训练需求,提出了一种面向不同训练内容的训练环境快速切换方法。首先,阐述了该方法的主要原理;然后,描述了训练科目编排优化、基于应用集群和容器调度的系统快速构建以及轻量级客户端集成3种关键技术;最后,给出了应用实例。应用实例表明,该方法实现了训练内容快速切换和训练资源动态重组,提升了训练效能。

关键词：训练环境切换时间矩阵特征矩阵

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现代天井植物景观营造实践

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安徽农学通报 2024年第1期30卷 41-44页

作者：聂丽平聂立刚方彬李德华深圳广信建设(集团)有限公司广东深圳518000

现代天井建筑由于引入玻璃建材和空调通风系统等,在建造形式上发生了很大改变,植物景观营造也产生一些变化。以现代天井植物景观营造实践为例,从场地现状、设计思路、落地实施和后期养护等方面,阐述以秋海棠、蕨类、苔藓和兰花等附生植... 详细信息

现代天井建筑由于引入玻璃建材和空调通风系统等,在建造形式上发生了很大改变,植物景观营造也产生一些变化。以现代天井植物景观营造实践为例,从场地现状、设计思路、落地实施和后期养护等方面,阐述以秋海棠、蕨类、苔藓和兰花等附生植物为主体的景观营造过程,为热带亚热带地区现代天井景观营造提供参考。

关键词：天井景观营造苔藓秋海棠蕨类

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Influence of Nb on Microstructure and Property of Low-Carbon Mn-Series Air-Cooled Bainitic Steel

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Journal of Iron and Steel Research International 2010年第1期17卷 49-53页

作者： WANG Yong-wei FENG Chun XU Feng-yun BAI bing-zhe fang Hong-sheng Department of Materials Science and Engineering Tsinghua University Beijing 100084 China

The effect of Nb on the microstructure evolution of low-carbon Mn-series air cooled bainitic steels has been studied by using thermomeehanical simulation machine, SEM, and TEM observation. The results show that the amount of ferrites is relatively higher in the steel without Nb than that of Nb-bearing steel under same deformation conditions, and the ferrites in Nb-bearing steel are more finer. The mechanical properties of the Nb-bearing steel are higher than those of the steel without Nb at the same finishing rolling temperature （FRT）, and the toughness of the Nb- bearing steel is about 100J higher than that of the steel without Nh at the finishing rolling temperature 750℃. The toughness of Nb microalloyed steel will be improved more effectively than that of the steel without Nb with the decrease of FRT.

关键词： Mn-series bainitic steel grain boundary allotriomorphic ferrite finishing rolling temperature Nb microalloyed steel toughness

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Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1

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International Journal of Oral Science 2022年第3期14卷 396-409页

作者： Yu Jin Zhen Liu Zhenxia Li Hairui Li Cheng Zhu Ruomei Li Ting Zhou bing fang Department of Orthodontics Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineCollege of StomatologyShanghai Jiao Tong UniversityNational Center for StomatologyNational Clinical Research Center for Oral DiseasesShanghai Key Laboratory of StomatologyShanghaiChina

Osteoarthritis(OA)is a prevalent joint disease with no effective treatment *** mechanical stimuli was demonstrated to be an essential factor for OA *** multiple studies have detected potential regulatory mechanisms underlying OA and have concentrated on developing novel treatment strategies,the epigenetic control of OA remains *** demethylase JMJD3 has been reported to mediate multiple physiological and pathological processes,including cell differentiation,proliferation,autophagy,and ***,the regulation of JMJD3 in aberrant force-related OA and its mediatory effect on disease progression are still *** this work,we confirmed the upregulation of JMJD3 in aberrant forceinduced cartilage injury in vitro and in ***,inhibition of JMJD3 by its inhibitor,GSK-J4,or downregulation of JMJD3 by adenovirus infection of sh-JMJD3 could alleviate the aberrant force-induced chondrocyte *** investigation illustrated that aberrant force induces JMJD3 expression and then demethylates H3K27me3 at the NR4A1 promoter to promote its *** experiments indicated that NR4A1 can regulate chondrocyte apoptosis,cartilage degeneration,extracellular matrix degradation,and inflammatory *** vivo,anterior cruciate ligament transection(ACLT)was performed to construct an OA model,and the therapeutic effect of GSK-J4 was *** importantly,we adopted a peptide-si RNA nanoplatform to deliver si-JMJD3 into articular cartilage,and the severity of joint degeneration was remarkably *** together,our findings demonstrated that JMJD3 is flow-responsive and epigenetically regulates OA *** work provides evidences for JMJD3 inhibition as an innovative epigenetic therapy approach for joint diseases by utilizing p5RHH-si RNA nanocomplexes.

关键词： Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1

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Concept, configuration, and application of on-board nanogrids for use in electric vehicles

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Science China(Technological Sciences) 2024年第7期67卷 2053-2073页

作者： ZHAO bing LI Yong WU fang WAN JiangHu CAI JiuQing YANG HaiTao LIU fang College of Electrical and Information Engineering Hunan UniversityChangsha 410082China Wuhan Second Ship Design and Research Institute Wuhan 430000China School of Automation Central South UniversityChangsha 410083China

Against the backdrop of increasingly serious climate change, researchers are attempting to extend macroscale carbon reduction research to smaller scales. With the rapid development and widespread application of electric vehicles(EVs), an effective approach for carbon reduction based on EVs has the potential to be developed. To coordinate and manage the EV platform in diverse application scenarios, the concept of an on-board nanogrid(OBNG), in which a nanogrid is combined with the EV, is proposed and defined, and the characteristics summarized. A configuration that includes a physical layer with the on-board hardware system;an information layer for logical control, energy management, and communication coordination;and an application layer that can cope with different working environments is proposed. A detailed introduction to the basic architecture and management mode of each layer is provided along with information concerning the relevant technologies for coordinated operation. New ideas and approaches to improve the existing performance are proposed, and finally, combined with a background of smart and low-carbon cities, major application scenarios are envisioned.

关键词： electric vehicle nanogrid energy management hybrid energy storage power electronics converter

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Clinical Characteristics,Diagnosis,and Therapeutics of COVID-19:A Review

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Current Medical Science 2023年第6期43卷 1066-1074页

作者： Na-na XIE Wen-cong ZHANG Jia CHEN fang-bing TIAN Jian-xin SONG Department of Infectious Diseases Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China

The novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)that suddenly emerged at the end of December 2019 and caused coronavirus disease 2019(COVID-19)continues to afflict humanity,not only seriously affecting healthcare systems but also leading to global social and economic *** of August 2022,there were approximately 580 million confirmed cases of COVID-19 and approximately 6.4 million confirmed deaths due to this *** data are sufficient to highlight the seriousness of SARS-CoV-2 *** most patients with COVID-19 present primarily with respiratory symptoms,an increasing number of extrapulmonary systemic symptoms and manifestations have been associated with *** the outbreak of COVID-19,much has been learned about the disease and its causative ***,great effort has been aimed at developing treatments and drug interventions to treat and reduce the incidence of *** this narrative review,we provide a brief overview of the epidemiology,mechanisms,clinical manifestations,diagnosis,and therapeutics of COVID-19.

关键词： coronavirus disease 2019 severe acute respiratory syndrome coronavirus 2 mechanism clinical manifestations diagnosis therapeutics

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非血缘脐血移植后肠道急性移植物抗宿主病的特点分析

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中国组织工程研究 2024年第25期28卷 3955-3959页

作者：涂美娟张春丽邓莉方冰孙光宇朱小玉章新琼安徽医科大学护理学院安徽省合肥市230601 中国科学技术大学附属第一医院(安徽省立医院)血液科安徽省合肥市230001

背景:尽管非血缘脐血移植有望成为治愈恶性血液病的重要方法,但移植后肠道急性移植物抗宿主病方面的表现及临床特点仍然需要深入研究。目的:分析非血缘脐血移植后发生肠道急性移植物抗宿主病的临床特点。方法:2016年12月至2020年12月中... 详细信息

背景:尽管非血缘脐血移植有望成为治愈恶性血液病的重要方法,但移植后肠道急性移植物抗宿主病方面的表现及临床特点仍然需要深入研究。目的:分析非血缘脐血移植后发生肠道急性移植物抗宿主病的临床特点。方法:2016年12月至2020年12月中国科学技术大学附属第一医院血液科造血干细胞移植亚专科668例恶性血液病患者接受非血缘脐血移植治疗,其中138例发生肠道急性移植物抗宿主病,男性76例,女性62例,移植时中位年龄13(1-62)岁。所有患者采取清髓性不含抗人胸腺细胞球蛋白方案进行预处理,以及采用环孢素A联合霉酚酸酯预防移植物抗宿主病。结果与结论:①非血缘脐血移植后肠道急性移植物抗宿主病患者均出现不同程度的腹泻,粪便为黄绿色以及黄褐色水样便或者黏液便,其中53例(38.4%)患者出现血便,82例(57.9%)患者伴有皮肤受累,18例(13.0%)患者继发肠道细菌感染,90例(65.2%)患者合并巨细胞病毒血症;②进一步比较1-2级肠道急性移植物抗宿主病(70例,50.7%)与3-4级肠道急性移植物抗宿主病(68例,49.3%)患者的临床特点,发现3-4级肠道急性移植物抗宿主病患者年龄大于1-2级肠道急性移植物抗宿主病患者(P<0.001),更易合并巨细胞病毒血症(P=0.035),腹泻持续时间更长(P=0.00),住院时间也明显增加(P<0.001),而两组患者在性别、移植前疾病状态、供受者HLA匹配度、疾病诊断、合并皮肤急性移植物抗宿主病、继发肠道感染率等方面无显著差异;③结果表明:非血缘脐血移植后肠道急性移植物抗宿主病的临床特点比较复杂,严重影响患者的预后和生活质量,需要及早识别,精准治疗。

关键词：非血缘脐血移植急性移植物抗宿主病肠道急性移植物抗宿主病腹泻

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Two-photon dual-channel fluorogenic probe for in situ imaging the mitochondrial H_(2)S/viscosity in the brain of drosophila Parkinson’s disease model

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Chinese Chemical Letters 2020年第11期31卷 2903-2908页

作者： Zhijie fang Zhe Su Wenjing Qin Hao Li bing fang Wei Du Qiong Wu Bo Peng Peng Li Haidong Yu Lin Li Wei Huang Key Laboratory of Flexible Electronics(KLOFE)&Institute of Advanced Materials(1AM) Nanjing Tech University(NanjingTech)Nanjing 211816China Shaanxi Institute of Flexible Electronics(SIFE)&Institute of Biomedical Materials&Engineering(IBME) Northwestern Polytechnical University(NPU)Xi'an 710072China

H2S is an essential gas signal molecule in cells,and viscosity is a key internal environmental *** studies have shown that H_(2)S acts as a cytoarchitecture agent and gas transmitter in many tissues,e.g.,as a regulator of neuroendocrine in the brain for mediating vascular tone in blood *** viscosity is an important parameter for judging whether mitochondrial function is *** has been reported that oxidative stress and mitochondrial dysfunction are connected with Parkinson’s disease(PD),and the protective role of H_(2)S in PD models has been extensively ***,Mito-HS,a new two-photon fluorescent probe was demonstrated to detect cross-talk between the two channels of mitochondrial viscosity and H_(2)S ***,this probe could detect the relative amount of and changes in mitochondrial H2S in situ due to the reduced mitochondrial targeting ability after reaction with H_(2)*** results show that H2S in mitochondria is inversely related to *** PD model has a lower H2S in mitochondria and a higher mitochondrial viscosity than did the *** result is important for our deep understanding of PD and its causes.

关键词： Two-photon H_(2)S Viscosity Fluorogenic probe Parkinson’s disease

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