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Evaluation of phytochemical properties and larvicidal activities of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula against Aedes aegypti

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Asian Pacific Journal of Tropical Medicine 2019年第5期12卷 224-231页

作者： Ananta Swargiary Manita Daimari Mritunjoy Roy Dipanjali Haloi bijit ramchiary Department of Zoology Bodoland University Department of Zoology Kokrajhar Govt.College

Objective: To investigate the phytochemical, antioxidant and larvicidal property of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula against Aedes ***: Antioxidant capacity of methanolic extract of the plants was studied by 2,2-Diphenyl-1-picryl-hydrazyl-hydrate(DPPH) assay, ferric reducing antioxidant power assay, 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) assay(ABTS), thiobarbituric acid reactive substance(TBARS) assay, superoxide anion scavenging activity and total antioxidant activity assay following standard *** phenolic content, total flavonoid content, carbohydrate, and plant protein were also estimated following standard *** property of plant extracts were determined following World Health Organization standard ***, glutathione-s-transferase(GST) and acetylcholinesterase(AchE) inhibitory property was also tested ***: Phytochemically, high protein, carbohydrate and phenolic were found in Terminalia chebula, while Cynodon dactylon showed high flavonoid ***, high antioxidant activity was found in Terminalia chebula with IC_(50) values at 13.7, 2.9, 45.2 and 46.0 μg/mL in DPPH, ABTS, TBARS and superoxide anion scavenging activity, *** study showed strongest activity in Spilanthes acmella followed by Cynodon dactylon, and Clerodendrum viscosum and Terminalia *** and AchE of Aedes aegypti larvae showed reduced enzyme activity when pre-incubated with Cynadon dactylon and Spilanthes ***: The methanolic crude extracts of Cynodon dactylon, Clerodendrum viscosum, Spilanthes acmella and Terminalia chebula possess strong antioxidant and larvicidal property against Aedes aegypti and therefore, may be further investigated for the molecular mode of action.

关键词： Larvicide Glutathione S-transferase Acetylcholinesterase Udalguri district Aedes aegypti

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