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Non-adiabatic holonomic quantum operations in continuous variable systems

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Science China(Physics,Mechanics & Astronomy) 2024年第6期67卷 12-19页

作者： Hao-Long Zhang Yi-Hao Kang Fan Wu Zhen-biao yang Shi-biao Zheng Fujian Key Laboratory of Quantum Information and Quantum Optics College of Physics and Information EngineeringFuzhou UniversityFuzhou 350116China

Quantum operations by utilizing the underlying geometric phases produced in physical systems are favoured due to their potential *** a system in a non-degenerate eigenstate undergoes an adiabatically cyclic evolution dominated by its Hamiltonian,it will get a geometric phase,referred to as the Berry *** a non-adiabatically cyclic evolution produces an Aharonov-Anandan geometric *** two types of Abelian geometric phases are extended to the non-Abelian cases,where the phase factors become matrix-valued and the transformations associated with different loops are *** and non-Abelian(holonomic)operations are prevalent in discrete variable systems,whose limited(say,two)energy levels,form the *** their developments in continuous systems have also been investigated,mainly due to that,bosonic modes(in,such as,cat states)with large Hilbert spaces,provide potential advantages in fault-tolerant quantum *** we propose a feasible scheme to realize non-adiabatic holonomic quantum logic operations in continuous variable systems with cat *** construct arbitrary single-qubit(two-qubit)gates with the combination of single-and two-photon drivings applied to a Kerr Parametric Oscillator(KPO)(the coupled KPOs).Our scheme relaxes the requirements of the previously proposed quantum geometric operation strategies in continuous variable systems,providing an effective way for quantum control.

关键词： cat qubit continuous variable systems non-Abelian

Thermal Performance of a 4 K High-Frequency Pulse Tube Cryocooler with Different Working Fluids

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Journal of Thermal Science 2024年第4期33卷 1468-1479页

作者： GAO Zhaozhao yang biao FAN Xiaoyu CHEN Liubiao WANG Junjie Key Laboratory of Cryogenic Science and Technology Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China

The high-frequency pulse tube cryocooler(HPTC)represents a promising miniature cryocooling technology due to its compact structure and the absence of low-temperature moving ***,limited to the non-ideal gas effect of4He,the HPTC is hard to obtain high cooling performance in the liquid helium temperature range.3He as the working fluid can effectively improve the cooling performance of the HPTC,but the high cost hinders its wide *** consideration of both cooling performance and cost-effectiveness,this paper explores the feasibility of utilizing^(3)He-^(4)He mixtures as the working fluid for ***,the experimental results of a developed HPTC based4He are *** a total power consumption of 575 W,the lowest temperature of 3.26 K was *** the measured cooling power at 4.2 K was 20.8 *** the theoretical utmost efficiency of the cryocooler was calculated in terms of the thermophysical properties of the working fluids,using ^(3)He-^(4)He mixtures with different compositions as the working *** whole machine modeling of the HPTC was further carried out,and the influence of the working fluids with different components on the structural parameters such as double-inlet and inertance tube,and operating parameters such as pressure and frequency were *** calculated results show that the cooling power is expected to be increased to36 mW and 53 mW if the equimolar ^(3)He-^(4)He mixture and pure ^(3)He are used,respectively.

关键词： high-frequency pulse tube cryocooler ^(3)He-^(4)He mixture liquid helium temperature thermally coupled

Experimental observation of spontaneous symmetry breaking in a quantum phase transition

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Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 34-39页

作者： Wen Ning Ri-Hua Zheng Jia-Hao Lu Fan Wu Zhen-biao yang Shi-biao Zheng Fujian Key Laboratory of Quantum Information and Quantum Optics College of Physics and Information EngineeringFuzhou UniversityFuzhou 350108China Hefei National Laboratory Hefei 230088China

Spontaneous symmetry breaking(SSB)plays a central role in understanding a large variety of phenomena associated with phase transitions,such as superfluid and *** far,the transition from a symmetric vacuum to a macroscopically ordered phase has been substantially *** process bridging these two distinct phases is critical to understanding how a classical world emerges from a quantum phase transition,but so far remains unexplored in *** here report an experimental demonstration of such a process with a quantum Rabi model engineered with a superconducting *** move the system from the normal phase to the superradiant phase featuring two symmetry-breaking field components,one of which is observed to emerge as the classical *** results demonstrate that the environment-induced decoherence plays a critical role in the SSB.

关键词： quantum phase transition Rabi model spontaneous symmetry breaking superconducting circuit Schrodinger cat states

Flow excitation mechanisms of unbalanced impeller forces after pump power-trip of ultra-high head pump-turbines

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Science China(Technological Sciences) 2024年第5期67卷 1602-1611页

作者： FU XiaoLong LI DeYou LV JingWei yang biao WANG HongJie WEI XianZhu School of Energy Science and Engineering Harbin Institute of TechnologyHarbin150001China State Key Laboratory of Hydro-Power Equipment Harbin Institute of Large Electrical MachineryHarbin150040China

To elucidate the dynamic mechanisms of unbalanced impellers in ultra-high head pump-turbines(PTs),this study employed a one-and three-dimensional coupled method to simulate the pump power-trip(PPT)process of an ultra-high head *** investigation revealed two novel pulsation frequency components,denoted as fDVand fINFT,associated with impeller *** pulsation intensities of these components were markedly higher than those of rotor-stator interaction frequency components in ultra-high head ***,the fDVcomponents exhibited pulsations at 1–2 times the rated rotation frequency of the impeller,spanning the entire transition ***,the fINFTcomponents constituted a complex frequency band with various frequency values,primarily occurring near conditions(Q=0,n=0,M=0,and d M/dt=0).These two pulsation frequency components were predominantly linked to the unsteady evolution of dean vortices inside the volute and complex transitions of the flow pattern within the impeller,*** is crucial to note that these unbalanced flow-induced impeller axial forces can elevate the risk of accidents where the rotor is subjected to significant upwind axial *** findings offer valuable insights into mitigating the risk of rotor lifting due to axial forces during PT events in ultra-high head PTs.

关键词： ultra-high head pump-turbine pump power-trip unbalanced impeller forces pressure pulsations flow pattern transitions

Bioinspired directional structures for inhibiting wetting on super-melt-philic surfaces above 1200°C

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International Journal of Extreme Manufacturing 2024年第4期6卷 337-346页

作者： Hujun Wang Xiuyuan Zhao Zhengcan Xie biao yang Jing Zheng Kai Yin Zhongrong Zhou Tribology Research Institute State Key Laboratory of Rail Transit Vehicle SystemSchool of Mechanical EngineeringSouthwest Jiaotong UniversityChengdu 610031People's Republic of China Hunan Key Laboratory of Nanophotonics and Devices School of PhysicsCentral South UniversityChangsha 410083People's Republic of China

Over the past two decades,superhydrophobic surfaces that are easily created have aroused considerable attention for their superior performances in various applications at room ***,there is a growing demand in special fields for the development of surfaces that can resist wetting by high-temperature molten droplets(>1200°C)using facile design and fabrication ***,bioinspired directional structures(BDSs)were prepared on Y2O3-stabilized ZrO2(YSZ)surfaces using femtosecond laser *** from the anisotropic energy barriers,the BDSs featured with no additional modifiers showed a remarkable increase from 9.2°to 60°in the contact angle of CaO–MgO–Al2O3–SiO2(CMAS)melt and a 70.1%reduction in the spreading area of CMAS at 1250°C,compared with polished super-CMAS-melt-philic YSZ ***,the BDSs demonstrated exceptional wetting inhibition even at 1400°C,with an increase from 3.3°to 31.3°in contact angle and a 67.9%decrease in spreading *** work provides valuable insight and a facile preparation strategy for effectively inhibiting the wetting of molten droplets on super-melt-philic surfaces at extremely high temperatures.

关键词： directional structures bioinspired design inhibiting wetting super-melt-philic superhydrophobic

Optimization of Microwave Heating Temperature Field Uniformity Based on DDPG Algorithm

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Optimization of Microwave Heating Temperature Field Uniformi...

Targeting a disintegrin and metalloprotease(ADAM)17-CD122 axis enhances CD8^(+)T cell effector differentiation and anti-tumor immunity

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作者： biao yang yang Chen Xiucai Chen Haoran Zhang Faculty of Information Engineering and Automation Kunming University of Science and Technology

This study employs the Deep Deterministic Policy Gradient(DDPG) algorithm in deep reinforcement learning to explore its potential in improving uniformity during microwave heating processes. Microwave heating is a crucial technology in the field of thermal processing, yet it often encounters issues with uneven temperature distribution in practical applications, which can affect product quality and processing efficiency. Traditional methods of microwave heating control often struggle to address this challenge. The advantage of the DDPG algorithm lies in its ability to learn policies in continuous action spaces, making it suitable for scenarios in microwave heating where continuous adjustment of power and radiation direction is necessary. In this study, we model the microwave heating system as a reinforcement learning environment, where an intelligent agent optimizes temperature distribution uniformity by adjusting microwave power and radiation direction. The agent uses temperature distribution uniformity as a reward signal and continuously optimizes its policy through the DDPG algorithm to achieve more uniform heating effects. Experimental results demonstrate significant performance advantages of the DDPG algorithm in microwave heating. Compared to traditional microwave heating control methods, we observe that DDPG agents converge more quickly to uniform temperature distributions, reducing energy waste and enhancing product quality and production efficiency. This provides new methods and insights for uniformity control in the field of microwave heating, highlighting the broad prospects of deep reinforcement learning in industrial heating processes.

关键词： microwave heating deep reinforcement learning temperature uniformity

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Signal Transduction and Targeted Therapy 2024年第7期9卷 3097-3111页

作者： Lina Sun Anjun Jiao Haiyan Liu Renyi Ding Ning Yuan biao yang Cangang Zhang Xiaoxuan Jia Gang Wang Yanhong Su Dan Zhang Lin Shi Chenming Sun Aijun Zhang Lianjun Zhang Baojun Zhang Department of Pathogenic Microbiology and Immunology School of Basic Medical SciencesXi’an Jiaotong UniversityXi’anShaanxi 710061China Institute of Infection and Immunity Translational Medicine InstituteXi’an Jiaotong University Health Science CenterXi’anShaanxi 710061China Key Laboratory of Environment and Genes Related to Diseases Ministry of EducationXi’anShaanxi 710061China Xi’an Key Laboratory of Immune Related Diseases Xi’anShannxi 710061China Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy Cancer InstituteXuzhou Medical UniversityXuzhouJiangsuChina Department of Pediatrics Qilu Hospital of Shandong UniversityJinanChina National Key Laboratory of Immunity and Inflammation Suzhou Institute of Systems MedicineChinese Academy of Medical Sciences&Peking Union Medical CollegeSuzhou 215123 JiangsuChina Key Laboratory of Synthetic Biology Regulatory Elements Suzhou Institute of Systems MedicineChinese Academy of Medical Sciences&Peking Union Medical CollegeSuzhou 215123 JiangsuChina

CD8^(+)T cell immune responses are regulated by multi-layer networks,while the post-translational regulation remains largely *** ectodomain shedding is an important post-translational process orchestrating receptor expression and signal transduction through proteolytic cleavage of membrane ***,by targeting the sheddase A Disintegrin and Metalloprotease(ADAM)17,we defined a post-translational regulatory mechanism mediated by the ectodomain shedding in CD8^(+)T *** and proteomic analysis revealed the involvement of post-translational regulation in CD8^(+)T cells.T cellspecific deletion of ADAM17 led to a dramatic increase in effector CD8^(+)T cell differentiation and enhanced cytolytic effects to eliminate pathogens and ***,ADAM17 regulated CD8^(+)T cells through cleavage of membrane ***17 inhibition led to elevated CD122 expression and enhanced response to IL-2 and IL-15 stimulation in both mouse and human CD8^(+)T ***,inhibition of ADAM17 in CD8^(+)T cells improved the efficacy of chimeric antigen receptor(CAR)T cells in solid *** findings reveal a critical post-translational regulation in CD8^(+)T cells,providing a potential therapeutic strategy of targeting ADAM17 for effective anti-tumor immunity.

关键词： immunity stimulation involvement

基于改进子载波预留算法的正交频分复用信号峰均比抑制方法研究

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电子与信息学报 2024年第4期46卷 1196-1202页

作者：刘子威杨彪赵珊珊杜鸿飞南京邮电大学南京210023

由于系统对线性元器件的要求非常严格,导致目前正交频分复用(OFDM)系统产生峰值平均功率比(PAPR)过高的问题,引起OFDM和基于OFDM的雷达一体化系统的信号失真,影响系统性能。针对该问题,该文提出了基于加权最小二乘法的子载波预留法(TR)... 详细信息

由于系统对线性元器件的要求非常严格,导致目前正交频分复用(OFDM)系统产生峰值平均功率比(PAPR)过高的问题,引起OFDM和基于OFDM的雷达一体化系统的信号失真,影响系统性能。针对该问题,该文提出了基于加权最小二乘法的子载波预留法(TR)。该算法首先将OFDM设计方案中的子载波分为数据子载波和预留的空白子载波,数据子载波调制数据子载波,空白子载波调制空白数据。然后利用原始数据通过加权最小二乘法得到最佳削峰系数和削峰数据,并将削峰数据调制在空白子载波上面。最后将削峰数据叠加到原始数据上,完成PAPR的抑制。仿真表明,基于加权最小二乘法的TR算法能够在1~3次迭代下实现良好的PAPR抑制效果,并且它的收敛速度相比于传统算法有了明显的提高。

关键词：正交频分复用峰值平均功率比子载波预留法

Metabolic reprogramming: a new option for the treatment of spinal cord injury

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Neural Regeneration Research 2025年第4期20卷 1042-1057页

作者： Jiangjie Chen Jinyang Chen Chao Yu Kaishun Xia biao yang Ronghao Wang Yi Li Kesi Shi Yuang Zhang Haibin Xu Xuesong Zhang Jingkai Wang Qixin Chen Chengzhen Liang Department of Orthopedics The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang ProvinceChina Orthopedics Research Institute of Zhejiang University Zhejiang UniversityHangzhouZhejiang ProvinceChina Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province HangzhouZhejiang ProvinceChina Clinical Research Center of Motor System Disease of Zhejiang Province HangzhouZhejiang ProvinceChina Qiandongnan Prefecture People’s Hospital KailiGuizhou ProvinceChina Department of Orthopedics Fourth Medical CenterChinese PLA General HospitalBeijingChina

Spinal cord injuries impose a notably economic burden on society,mainly because of the severe after-effects they *** the ongoing development of various therapies for spinal cord injuries,their effectiveness remains ***,a deeper understanding of metabolism has opened up a new therapeutic opportunity in the form of metabolic *** this review,we explore the metabolic changes that occur during spinal cord injuries,their consequences,and the therapeutic tools available for metabolic *** spinal cord metabolism is characterized by independent cellular metabolism and intercellular metabolic ***,spinal cord injury results in metabolic disorders that include disturbances in glucose metabolism,lipid metabolism,and mitochondrial *** metabolic disturbances lead to corresponding pathological changes,including the failure of axonal regeneration,the accumulation of scarring,and the activation of *** rescue spinal cord injury at the metabolic level,potential metabolic reprogramming approaches have emerged,including replenishing metabolic substrates,reconstituting metabolic couplings,and targeting mitochondrial therapies to alter cell *** available evidence suggests that metabolic reprogramming holds great promise as a next-generation approach for the treatment of spinal cord *** further advance the metabolic treatment of the spinal cord injury,future efforts should focus on a deeper understanding of neurometabolism,the development of more advanced metabolomics technologies,and the design of highly effective metabolic interventions.

关键词： axons glycolysis metabolic reprogramming metabolism mitochondria neural regeneration neuroprotection oxidative phosphorylation spinal cord injury therapy