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受输入饱和约束的导弹直接侧向力/气动力复合控制

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宇航学报 2012年第11期33卷 1630-1635页

作者：胥彪周荻哈尔滨工业大学航天学院哈尔滨150001

针对受输入饱和约束的直接侧向力与气动力复合控制的导弹,研究其自动驾驶仪设计问题。导弹的执行机构分别是舵机和侧向脉冲发动机。舵机提供的是连续的控制量,而侧向脉冲发动机提供的是离散的控制量。首先采用最优控制方法设计连续的舵... 详细信息

针对受输入饱和约束的直接侧向力与气动力复合控制的导弹,研究其自动驾驶仪设计问题。导弹的执行机构分别是舵机和侧向脉冲发动机。舵机提供的是连续的控制量,而侧向脉冲发动机提供的是离散的控制量。首先采用最优控制方法设计连续的舵控制器。再对设计好舵控回路的新受控弹体,基于含有界干扰项离散饱和系统不变集分析方法进行直接侧向力控制器的设计。设计过程中,充分考虑了舵偏角的饱和非线性因素以及侧向脉冲发动机点火数取整产生的量化误差。最后,利用数值仿真验证了所提出控制方法的有效性。

关键词：复合控制饱和非线性不变集量化误差

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湖田窑的历史地位和艺术赏析

佛山陶瓷 2022年第2期32卷 51-53页

作者：徐标南京文物有限责任公司南京210001

唐宋时期是我国陶瓷工业和艺术造诣的巅峰时期,此时名窑林立,有诸多器物传世。其中景德镇湖田窑在陶瓷历史上有着重要地位,其吸收与革新了历史的制作技艺与艺术造型,反应了宋代的审美趋向与时代精神。所制青白瓷与历代不同,青白相间,精... 详细信息

唐宋时期是我国陶瓷工业和艺术造诣的巅峰时期,此时名窑林立,有诸多器物传世。其中景德镇湖田窑在陶瓷历史上有着重要地位,其吸收与革新了历史的制作技艺与艺术造型,反应了宋代的审美趋向与时代精神。所制青白瓷与历代不同,青白相间,精美者可与五大名窑相媲美。当代收藏界与普罗大众对此的兴趣日益增长,但学界对湖田窑及影青瓷的分析往往集中在工艺特征上,对艺术分析尚有一定欠缺,所以对窑口、瓷器进行整体分析和实物品鉴都是有必要的。

关键词：湖田窑青白瓷文物鉴定

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地铁车辆段大库上下叠摞双层设计研究

现代城市轨道交通 2023年第7期 11-15页

作者：徐彪北京市轨道交通设计研究院有限公司北京100068

文章结合北京地铁R4线临河双层车辆段设计案例,从双层车辆段设置的适应性、运营使用功能、消防设计、经济效益等方面对大库上下叠摞双层车辆段的相关问题进行分析和研究,以期为地铁双层车辆段设计提供参考。

关键词：地铁车辆段大库上下叠摞双层车辆段设计

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New Dispersed Phase of Electrorheological Fluids:TiO_2 Coating Graphite Particles

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Journal of Materials Science & Technology 2000年第5期16卷 529-530页

作者： Sujuan xu+ and biao WANG (Harbin Institute of Technology, Harbin 150001, China) Shouqiang MEN and Kunquan LU (Institute of Physics, Chinese Academy of Sciences, Beijing 100080, China) Harbin Institute of Technology Harbin 150001 China Institute of Physics Chinese Academy of Sciences Beijing 100080 China

We have prepared novel coated particles, with a conductor graphite core and a dielectric TiO2 coating, as the dispersed phase of electrorheological fluids. One order of magnitude enhancement in the shear stress is obtained by using such composite particles, when it is compared with that of TiO2 particles. The experimental results show a way to get excellent ER system.

关键词： New Dispersed Phase of Electrorheological Fluids Graphite TiO

Interaction between XRCC1 Polymorphisms and Intake of Long-Term Stored Rice in the Risk of Esophageal Squamous Cell Carcinoma:A Case-Control Study

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Biomedical and Environmental Sciences 2011年第3期24卷 268-274页

作者： YU HongJie FU ChaoWei WANG JianMing xuE HengChuan xu biao Department of Epidemiology School of Public Health Fudan University Shanghai 200032 China Department of Epidemiology School of Public Health Nanjing Medical University Nanjing 210029 Jiangsu China Yangzhong People's Hospital Yangzhong 212200 Jiangsu China

Objective This study aimed to explore the roles of three common single nucleotide polymorphisms in the X-ray repair cross-complementing group-1 gene （XRCC1） and of life style factors and their possible interactions in the risk of esophageal squamous cell carcinoma （ESCC） in China. Methods A population-based case-control study of 432 cases and 915 controls was conducted in Yangzhong County, Jiangsu Province, China. Subjects were interviewed by trained interviewers using a structured questionnaire that included questions on demographics and life style. XRCC1 genotypes were analyzed using a polymerase chain reaction based restriction fragment length polymorphism （PCR-RFLP） assay. Unconditional logistic regression analysis was used to calculate adjusted odds ratios （aORs） and 95% confidence intervals （CIs） for associations of ESCC with XRCCI polymorphisms and lifestyle-related factors. Results Both the drinking of river water and alcohol intake history were significantly associated with an increased risk of ESCC among men with aORs of 4.20 （95% Ch 2.90-6.07） and 2.03 （95% Ch 1.43-2.89）, respectively. For women, the corresponding odds ratios were 8.37 （95% CI： 5.09-13.75） for river water drinking and 12.78 （95% CI： 2.69-60.69） for long-term stored rice intake. After the XRCC1 G28152A polymorphism was adjusted for potential confounders, subjects with GA and AA genotypes had an increased risk for ESCC （aOR： 1.21, 95% CI： 0.93-1.56）, compared with subjects with a GG genotype, and a positive multiplicative interaction between intake of long-term stored rice and the XRCC1 G28152A polymorphism was observed （P=O.009）.Conclusions Our findings suggest that both lifestyle-related factors, including drinking river water, long-term stored rice and alcohol intake, and the XRCC1 G28152A polymorphism were possible risk factors for ESCC, and that the XRCC1 G28152A polymorphism modified the effect of long-term stored rice intake on the risk of ESCC among Chinese people.

关键词： XRCC1 Polymorphism Lifestyle-related factors Esophageal squamous cell carcinoma Chinese people

Evaluation of metoprolol standard dosing pathway in Chinese patients with acute coronary syndrome:a prospective multicenter single-arm interventional study

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Journal of Geriatric Cardiology 2023年第4期20卷 256-267页

作者： Xiao-Yun YIN Yun-Mei ZHANG Ai-Dong SHEN Jing-Ping WANG Zhe-xun LIAN Yi-Bing SHAO Wen-Qi ZHANG Shu-Ying ZHANG Yang ZHENG Kang CHENG biao xu Cheng-Xing SHEN Rong-Chong HUANG Jin-Cheng GUO Guo-Sheng FU Dong-Kai SHAN Dan-Dan LI Yun-Dai CHEN Senior Department of Cardiology the Sixth Medical CentreChinese PLA General HospitalBeijingChina Medical School of Chinese PLA BeijingChina Department of Cardiology Yunnan First People’s HospitalKunmingChina Department of Heart Center Beijing Friendship HospitalCapital Medical UniversityBeijingChina Department of Cardiology Shanxi Cardiovascular HospitalTaiyuanChina Department of Cardiology the Affiliated Hospital of Qingdao UniversityQingdaoChina Department of Cardiology Qingdao Municipal HospitalQingdaoChina Department of Cardiology China-Japan Union Hospital of Jilin UniversityChangchunChina Department of Cardiology the Affiliated Zhongshan Hospital of Dalian UniversityZhongshanChina Cardiovascular Center the First Hospital of Jilin UniversityChangchunChina Department of Cardiology the Affiliated Hospital of Northwest University&Xi’an No.3 HospitalXi’anChina Department of Cardiology Nanjing Drum Tower HospitalNanjing University Medical SchoolNanjingChina Department of Cardiology Shanghai Jiao Tong University Affiliated Sixth People’s HospitalShanghaiChina Department of Cardiology Beijing Friendship HospitalCapital Medical UniversityBeijingChina Department of Cardiology Beijing Luhe HospitalCapital Medical UniversityBeijingChina Department of Cardiology School of MedicineSir Run Run Shaw HospitalZhejiang UniversityHangzhouChina

OBJECTIVE To evaluate the feasibility and tolerability of metoprolol standard dosing pathway(MSDP)in Chinese patients with acute coronary syndrome(ACS).METHODS In this multicenter,prospective,open label,single-arm and interventional study that was conducted from February 2018 to April 2019 in fifteen Chinese hospitals.A total of 998 hospitalized patients aged≥18 years and diagnosed with ACS were *** MSDP was applied to all eligible ACS patients based on the standard treatment recommended by international *** primary endpoint was the percentage of patients achieving the target dose at discharge(V2).The secondary endpoints included the heart rate and blood pressure at V2 and four weeks after discharge(V4),and percentage of patients experiencing bradycardia(heart rate<50 beats/min),hypotension(blood pressure<90/60 mmHg)and transient cardiac dysfunction at V2 and *** Of the 998 patients,29.46%of patients achieved the target dose(≥95 mg/d)at *** total population was divided into two groups:target group(patients achieving the target dose at V2)and non-target group(patients not achieving the target dose at V2).There was significant difference in the reduction of heart rate from baseline to discharge in the two groups(-4.97±11.90beats/min vs.-2.70±9.47 beats/min,P=0.034).There was no significant difference in the proportion of bradycardia that occurred in the two groups at V2(0 vs.0,P=1.000)and V4(0.81%vs.0.33%,P=0.715).There was no significant difference in the proportion of hypotension between the two groups at V2(0.004%vs.0.004%,P=1.000)and V4(0 vs.0.005%,P=0.560).No transient cardiac dysfunction occurred in two groups during the study.A total of five adverse events(1.70%)and one serious adverse event(0.34%)were related to the pathway in target *** In Chinese ACS patients,the feasibility and tolerability of the MSDP have been proved to be acceptable.

关键词： patients prospective coronary

The transcriptome of circulating cells indicates potential biomarkers and therapeutic targets in the course of hypertension-related myocardial infarction

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Genes & Diseases 2021年第4期8卷 555-568页

作者： Zilun Wei Yining Yang Qiaoling Li Yong Yin Zhonghai Wei Wenfeng Zhang Dan Mu Jie Ni xuan Sun biao xu Department of Cardiology Nanjing Drum Tower HospitalClinical College of Nanjing Medical UniversityNanjingJiangsu Province210008PR China Department of Cardiology Nanjing Drum Tower HospitalNanjing University Medical SchoolNanjingJiangsu Province210008PR China

Hypertension(HT)is the most common public-health challenge andshows a high inci-dence around the *** diseases are the leadingcause of mortality and morbidity among the elderly(age>65 years)in the ***,there is widespread acceptanceof the causal link between HT and acute myocardial infarction(MI).This is the first data-mining study to identify co-expressed differentially expressed genes(Co-DEGs)between HT and MI(rela-tive to nommal control)and to uncover potential biomarkers and therapeutic targets of HT-related *** thismanuscript,HT-specfcDEGs andMl-specific DEGs and dffretially expressed microRNAs(DE-miRNAs)were identifhed in Gene Expression Omnibus(GEO)datasets GSE24752,GSE60993,GSE62646,and GSE24548 after data consolidation and batch ***-quently,enichmentin Gene Ontology(GO)terms and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathways as well as protein-protein interaction networks were identified,and single-gene gene set enrichment analysis was performed to determine the affected biological cate-gories and ***-matching of the results on cCo-DE-miRNAs and predicted miRNAs tar-geting the Co-DEGs wasconducted and discussed as *** found thatMYC and HIST1H2BO may be associatedwith HT,whereas FCGR 1A,FYN,KLRD1,KLRB1,and FOLR3 may be implicated in ***,Co-DEGs FOLR3 and NFE2 with predicted miRNAs and DE-miRNAs,especially miR-7 and miR-548,may be significantly associated and show huge potential as a new set of novel bio-markers and important molecular targets in the course of HT-related MI.

关键词： Biological function Blood Hypertension Microarray Myocardial infarction Pathway

分光型激光诱导磷光系统标定及气体温度场测量

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工程热物理学报 2024年第4期45卷 1062-1068页

作者：陈满福张彪李健许传龙大型发电装备安全运行与智能测控国家工程研究中心东南大学能源与环境学院南京210096

受光学系统和图像传感器的影响,分光型激光诱导磷光成像系统存在明显的空间响应不均匀性,导致磷光光谱强度比法无法获得准确的温度分布。针对此问题,基于最小二乘线性拟合原理,本文提出一种分光型激光诱导磷光成像系统响应空间不均匀的... 详细信息

受光学系统和图像传感器的影响,分光型激光诱导磷光成像系统存在明显的空间响应不均匀性,导致磷光光谱强度比法无法获得准确的温度分布。针对此问题,基于最小二乘线性拟合原理,本文提出一种分光型激光诱导磷光成像系统响应空间不均匀的校正方法,获得了系统的校正矩阵。进一步开展了磷光光谱强度比标定实验,建立了磷光光谱强度比与温度的关系。在此基础上,在室温环境下(热电偶参考温度26.34℃)开展了冷态气体射流的二维温度场测量实验研究。结果表明:系统校正前,平均温度测量结果为46.58℃,标准方差为15.18℃,相对误差为76.84%;系统校正后,平均温度测量结果为26.06℃,标准方差为1.83℃,相对误差为1.07%。证明了基于最小二乘线性拟合的空间不均匀校正方法,可显著改善分光型激光诱导磷光成像系统的空间响应不均匀性,提高温度测量准确度。

关键词：激光诱导磷光响应特性多点校正法强度比法温度场测量

考虑公交接驳的地铁网络韧性评估及故障修复策略

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都市快轨交通 2023年第1期36卷 93-98页

作者：崔欣路庆昌徐标李静长安大学电子与控制工程学院西安710064

地铁网络突发重大事故后,通常会启动公交接驳疏散滞留乘客。提出衡量网络性能的网络效率可达性指标,考虑地铁站点发生故障后公交接驳对乘客的紧急疏散作用。基于网络效率可达性指标构建韧性评估模型,提出多故障下以韧性最大化为目标的... 详细信息

地铁网络突发重大事故后,通常会启动公交接驳疏散滞留乘客。提出衡量网络性能的网络效率可达性指标,考虑地铁站点发生故障后公交接驳对乘客的紧急疏散作用。基于网络效率可达性指标构建韧性评估模型,提出多故障下以韧性最大化为目标的修复策略,并以上海市地铁网络为例进行实例研究。研究结果表明,单个站点发生故障后启动公交接驳可使网络性能损失降低5.1%;占网络站点总数2.14%的多个站点发生故障后启动公交接驳可使网络性能损失降低13.48%;多故障下相比基于站点度、介数、脆弱性等评估得到的修复序列,基于韧性评估得到的最优修复序列可使网络性能累积损失降低2.86%。此外,研究发现在公交接驳场景下,当地铁网络中多个站点发生故障后,优先修复客流量大、站点周边线路稀疏、失效后造成影响大且修复时间短的站点,有助于降低网络性能的累积损失。

关键词：城市轨道交通韧性评估修复策略公交接驳网络性能脆弱性