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Artificial intelligence:New age of transformation in petroleum upstream

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Petroleum Research 2022年第1期7卷 106-114页

作者： Parth Solanki Dhruv Baldaniya Dhruvikkumar Jogani bhavesh Chaudhary Manan Shah Ameya Kshirsagar School of Petroleum Technology Pandit Deendayal Petroleum UniversityGandhinagar382007GujaratIndia Department of Chemical Engineering School of TechnologyPandit Deendayal Petroleum UniversityGandhinagar382007GujaratIndia Department of Information Technology Symbiosis Institute of TechnologyPuneMaharashtraIndia

In the Oil and Gas industry,the implementation of artificial intelligence techniques gives advantages of better use of existing *** provides better future outcomes,which makes it an essential technology in the operations of the *** this paper,the implementation of artificial intelligence techniques for good planning,determination of reservoir rock properties,drilling optimization and production facilities are *** precise knowledge of permeability and porosity,reservoir engineers can develop robust reservoir development plan and manage hydrocarbon recovery *** porosity prediction,wire-line log data and seismic attributes are used in artificial intelligence-based *** prediction has been discussed by considering the different types of well-log data in the modeling of artificial intelligence techniques to predict single-phase *** of specific developed problems during the determination of permeability in the actual experiment is also *** intelligence techniques are used in the design and accurate analysis of the drilling *** assists in the selection of drill bit and drilling-related *** a reservoir cannot produce naturally,we can select a suitable artificial lift and design the production system using Artificial intelligence *** EOR methods,SADA and NAVA knowledge base systems are *** intelligence can help in optimizing production,improve production efficiency and recovery of hydrocarbons.

关键词： Artificial neural network Enhanced oil recovery Fuzzy logic system Artificial lift Permeability Porosity

Improving the charge kinetics through in-situ growth of NiSe nanoparticles on g-C_(3)N_(4)nanosheets for efficient hybrid supercapacitors

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Journal of Energy Chemistry 2023年第12期87卷 304-313,I0008页

作者： Somnath R.Khaladkar Oshnik Maurya Girish Gund bhavesh Sinha Deepak Dubal R.R.Deshmukh Archana Kalekar Department of Physics Institute of Chemical Technology(ICT)MatungaMumbai 400019MaharashtraIndia Department of Physics Mahatma Phule ArtsScience and Commerce CollegePanvel 410206MaharashtraIndia National Center for Nanoscience and Nanotechnology University of MumbaiMumbai 400032MaharashtraIndia Centre for Materials Science School of Chemistry and PhysicsQueensland University of TechnologyBrisbane QLD 4000Australia

Nickel selenide(NiSe)has been a promising positive electrode for hybrid supercapacitors due to its multiple oxidation states,tunability,and high specific ***,sluggish ion transfers and particle agglomeration hamper its electrochemical *** the present study,we have grown NiSe nanoparticles on two-dimensional(2D)graphitic carbon nitride(g-C_(3)N_(4))nanosheets to realize three-dimensional(3D)*** 2D support,high nitrogen content,and features of g-C_(3)N_(4)enhanced the specific capacity of the NiSe/g-C_(3)N_(4)nanocomposite *** resulting nanocomposite shows a specific capacity of 320 mA h g^(-1)at a current density of 1 A g^(-1),which is considerably higher than pristine ***,the hybrid supercapacitor(HSC)device was fabricated using NiSe/g-C_(3)N_(4)composite as positive and activated carbon(AC)as negative *** cell delivered an energy density of 52.5 Wh kg^(-1)at a power density of 1488 W kg^(-1)with excellent cyclic stability of 84.9%over 8000 *** electrochemical performance enhancement corresponds to a 3D structure,high electrochemical active sites,and improved charge transportation at the electrode/electrolyte ***,the present work offers an easy approach and architectural design for high-performance HSC.

关键词： Nickel selenide Graphitic carbon nitride Nanocomposite Specific capacity Hybrid supercapacitor

Montmorillonite/Poly(L-Lactide)microcomposite spheres as reservoirs of antidepressant drugs and their controlled release property

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Asian Journal of Pharmaceutical Sciences 2015年第5期10卷 452-458页

作者： Shalini Rajkumar bhavesh D.Kevadiya Hari C.Bajaj Institute of Science Nirma UniversityAhmedabad 382481GujaratIndia Discipline of Inorganic Materials and Catalysis Central Salt and Marine Chemicals Research InstituteCouncil of Scientific and Industrial Research(CSIR)Gijubhai Badheka MargBhavnagar 364021GujaratIndia

This work evaluates intercalation of Nortriptyline(NT)and Venlafaxine(VFX)in an interlayer gallery of Na^(+)-MMT(Montmorillonite),which was further compounded with Poly(LLactide)(PLLA)to form microcomposite spheres(MPs)for oral controlled drug *** XRD patterns,thermal and spectroscopic analyses indicated intercalation of drugs into the MMT interlayer that was stabilized by electrostatic *** significant changes in structural and functional properties of drugs were found in the MMT *** vitro drug release studies showed controlled release pattern.

关键词： Nortriptyline Venlafaxine Poly(L-Lactide) Montmorillonite Antidepressant

Quantitation of tadalafil in human plasma using a sensitive and rapid LC-MS/MS method for a bioequivalence study

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Journal of Pharmaceutical Analysis 2018年第4期8卷 271-276页

作者： Abhaysingh Bhadoriya bhavesh Dasandi Dharmesh Parmar Priyanka A. Shah Pranav S. Shrivastav Bioanalytical Department Synchron Research Services Pvt. Ltd. Department of Chemistry School of Sciences Gujarat University

A highly sensitive liquid chromatography-tandem mass spectrometry（LC-MS/MS） method was developed for the determination of tadalafil（TAD） in human plasma. TAD and its deuterated internal standard（IS）, tadalafil-d3, were extracted from 200 mL plasma using Phenomenex Strata-X-C 33 m extraction cartridges. Chromatographic analysis was carried out on Synergi Hydro-RP C18（100 mm × 4.6 mm, 4 mm）column with a mobile phase consisting of methanol and 10 m M ammonium formate, p H 4.0（90：10, v/v）,delivered at a flow rate of 0.9 m L/min. Quantitation of the protonated analyte was done on a triple quadrupole mass spectrometer using multiple reaction monitoring via electrospray ionization. The precursor to product ions transitions monitored for TAD and TAD-d3 were m/z 390.3-268.2 and m/z393.1-271.2, respectively. The calibration curve was linear over the concentration range of 0.50–500 ng/m L with correlation coefficient, r2 Z 0.9994. Acceptable intra-batch and inter-batch precision（r3.7%） and accuracy（97.8% to 104.1%） were obtained at five concentration levels. The recovery of TAD from spiked plasma was highly precise and quantitative（98.95% to 100.61%）. Further, the effect of endogenous matrix components was minimal. TAD was found to be stable under different storage conditions in human plasma and also in whole blood samples. The validated method was successfully used to determine TAD plasma concentration in a bioequivalence study with 20 mg TAD tablets in 24 healthy volunteers. Method performance was evaluated by reanalyzing 115 study samples.

关键词： Tadalafil Tadalafil-d3 LC-MS/MS Sensitive Bioequivalence study Human plasma

Sensitive and rapid determination of amantadine without derivatization in human plasma by LC–MS/MS for a bioequivalence study

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Journal of Pharmaceutical Analysis 2018年第3期8卷 202-207页

作者： Abhaysingh Bhadoriya Shivprakash Rathnam bhavesh DasANDi Dharmesh Parmar Mallika Sanyal Pranav S.Shrivastav Bioanalytical Department Synchron Research Services Pvt.Ltd Department of Chemistry St.Xavier's College Department of Chemistry School of Sciences Gujarat University

A highly sensitive, rapid and rugged liquid chromatography-tandem mass spectrometw （LC-ESI-MS/MS） method was developed for reliable estimation of amantadine （AMD）, an antiviral drug in human plasma. The analyte and internal standard （IS）, amantadine-d6 （AMD-d6）, were extracted from 200μL plasma by solid phase extraction on Phenomenex Strata-X-C 33 ~t cartridges. Chromatography was performed on Synergi^TM Hydro-RP C18 （150 mm×4.6 mm, 4 μm） analytical column using a mixture of acetonitrile and 10 mM ammonium formate, pH 3.0 （80：20, v/v） as the mobile phase. Detection and quantitation was done by multiple reaction monitoring in the positive ionization mode for AMD （m/z 152.1→ 135.1 ） and IS （m/z 158.0 → 141.1） on a triple quadrupole mass spectrometer. The assay was linear in the concentration range of 0.50-500 ng/mL with correlation coefficient （r^2）〉 0.9969. The limit of detection of the method was 0.18 ng/mL The intra-batch and inter-batch precisions were 〈 5.42% and the accuracy varied from 98.47% to 105.72%. The extraction recovery of amantadine was precise and quantitative in the range of 97.89%-100.28%. IS-normalized matrix factors for amantadine varied from 0.981 to 1.012. The stability of AMD in whole blood and plasma was evaluated under different conditions. The developed method was successfully applied for a bioequivalence study with 100 mg of AMD in 32 healthy volunteers. The reproducibility of the assay was determined by reanalysis of 134 subject samples.

关键词： Amantadine Amantadine-d6 LC-ESI-MS/MS Sensitive Bioequivalence study Human plasma

Phoenix phylogeny, and analysis of genetic variation in a diverse collection of date palm(Phoenix dactylifera) and related species

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Plant Diversity 2019年第5期41卷 330-339页

作者： Srinivasa R.Chaluvadi Porter Young Kentrez Thompson Bochra Amina Bahri bhavesh Gajera Subhash Narayanan Robert Krueger Jeffrey L.Bennetzen Department of Genetics University of GeorgiaAthensGAUSA Institute of Plant Breeding Genetics and Genomics(Department of Crop and Soil Sciences)and Department of Plant BiologyUniversity of GeorgiaAthensGA 30602USA Laboratory of Bioaggressors and Integrated Protection in Agriculture The National Agronomic Institute of TunisiaUniversity of Carthage43 Avenue Charles-NicolleTunis 1082Tunisia Anand Agricultural University AnandIndia USDA-ARS National Clonal Germplasm Repository for Citrus and Dates RiversideCAUSA

Date palm(Phoenix dactylifera),one of the most ancient crops,is grown commercially in>30 *** whole plastome assemblies,phylogenetic analyses revealed that cultivated date palm accessions share the same clade with Phoenix sylvestris,Phoenix pusilla and Phoenix acaulis,which are native to the Indian subcontinent,and Phoenix caespitosa that is native to the Arabian Peninsula and the deserts of *** of genetic diversity and genetic relationships among date palm accessions from 13 producing countries involved 195 date palm accessions that were genotyped at 19 microsatellite *** genetic diversity was observed,with many accessions heterozygous for most markers in this clonally propagated *** average number of alleles per locus(42.1),expected heterozygosity(0.8),observed heterozygosity(0.47)and fixation indices(FST=0.42)demonstrated substantial genetic diversity and population *** accessions were found to have the richest allelic diversity,and the most private *** model-based Bayesian method indicated that these accessions could be broadly divided into two structure groups,one group with predominantly African accessions and another predominantly *** germplasm,especially from Tunisia and Iraq,deviated from this *** accessions in the STRUCTURE-derived groups were found to be genetic admixtures,with gene flow between Asian and African *** and Pakistani date palms were found to be most closely related to North African germplasm.

关键词： Date palm improvement Germplasm dissemination Plastome Simple sequence repeats

Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains

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Asian Journal of Andrology 2021年第2期23卷 178-187页

作者： Junaid Kashir bhavesh V Mistry Maha Adel Gumssani Muhammad Rajab Reema Abu-Dawas Falah AlMohanna Michail Nomikos Celine Jones Raed Abu-Dawud Nadya Al-Yacoub Kevin Coward F Anthony Lai Abdullah M Assiri College of Medicine Alfaisal UniversityRiyadh 11533Saudi Arabia Department of Comparative Medicine King Faisal Specialist Hospital and Research CentreRiyadh 11211Saudi Arabia College of Medicine QU HealthQatar UniversityDoha PO Box 2713Qatar Nuffield Department of Women’s and Reproductive Health University of OxfordLevel 3Women’s CentreJohn Radcliffe HospitalOxford OX39DUUnited Kingdom Biomedical Research Centre Qatar UniversityDoha PO Box 2713Qatar

Sperm-specific phospholipase C zeta(PLCζ)initiates intracellular calcium(Ca2+)transients which drive a series of concurrent events collectively termed oocyte *** investigations have linked abrogation and absence/reduction of PLCζwith forms of male infertility in humans where oocyte activation ***,very few studies have examined potential relationships between PLCζand advancing male age,both of which are increasingly considered to be major effectors of male *** efforts in humans may be hindered by inherent PLCζvariability within the human population,alongside a lack of sufficient controllable ***,utilizing immunoblotting,immunofluorescence,and quantitative reverse transcription PCR(qRT-PCR)we examined for the first time PLCζprotein levels and localization patterns in sperm,and PLCζmRNA levels within testes,from mice at 8 weeks,12 weeks,24 weeks,and 36 weeks of age,from two separate strains of mice,C57BL/6(B6;inbred)and CD1(outbred).Collectively,advancing male age generally diminished levels and variability of PLCζprotein and mRNA in sperm and testes,respectively,when both strains were ***,advancing male age altered the predominant pattern of PLCζlocalization in mouse sperm,with younger mice exhibiting predominantly post-acrosomal,and older mice exhibiting both post-acrosomal and acrosomal populations of PLCζ.However,the specific pattern of such decline in levels of protein and mRNA was ***,our results demonstrate a negative relationship between advancing male age and PLCζlevels and localization patterns,indicating that aging male mice from different strains may serve as useful models to investigate PLCζin cases of male infertility and subfertility in humans.

关键词： ageing fertilization male infertility oocyte activation phospholipase C zeta sperm

The Corpse Is a Silent Witness Who Never Lies—A Case Report

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Forensic Medicine and Anatomy Research 2014年第3期2卷 43-47页

作者： Vijay Pal Pawan Mittal Jitender K. Jakhar Yogesh Kumar Vashist A. D. Aggarwal bhavesh Bohra Department of Forensic Medicine Government Medical College Patiala India Department of Forensic Medicine Jhalawar Medical College Jhalawar India Department of Forensic Medicine Pt. B. D. Sharma PGIMS Rohtak Pt. Bhagwat Dayal Sharma University of Health Sciences Rohtak India Department of Forensic Medicine Pt. B. D. Sharma PGIMS Rohtak Pt. Bhagwat Dayal Sharma University of Health Sciences Rohtak India Pt. Bhagwat Dayal Sharma University of Health Sciences Rohtak India

There are two very common sayings about corpse (dead body). The first common saying is that “the corpse is a silent witness who never lies” and the other common saying is that “the dead body is extremely eloquent and honestly informative, if one exercises patience in listening to it.” Both these sayings were proved in one of our cases. In the present case, decomposed body of an unidentified female individual aged about 25 - 26 years was recovered from the bank of western Yamuna canal in Haryana. The police made the efforts for establishing the identity of the deceased but could not succeed. The body was forwarded to the district hospital for autopsy along with the inquest report. However, the body being in advanced stage of decomposition so it was referred from the district hospital to the department of Forensic Medicine, PGIMS, Rohtak (Haryana) for the examination and the expert opinion regarding the cause of death. The findings observed on examination of the body helped to deduce the cause, time and manner of death whereas certain important objective features of identification were also observed and ultimately proper identity of the deceased could be established beyond the reasonable doubt by DNA profile of the samples preserved at autopsy. The autopsy findings, DNA profile and the results of examination of other materials (exhibits) taken from the body not only revealed the truth from the silent witness—the corpse, but also provided objective and scientific evidence to establish the corpus delicti in this case.

关键词： Corpus Delicti Rape Throttling Murder Putrefaction DNA Profile

Gastric metastases of oral carcinoma resulting from percutaneous endoscopic gastrostomy placement via the introducer technique

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Gastroenterology Report 2013年第3期1卷 211-213页

作者： Jun Liang Teh Reuben K.Wong Michelle Gowans Asim Shabbir bhavesh Doshi David E.Ong Victor T.Fan Division of General Surgery National University HospitalSingapore Division of Gastroenterology&Hepatology National University HospitalSingapore Department of Oral and Maxillofacial Surgery National University HospitalSingapore

*** cell implantation is a rare complication in patients with head and neck cancers,who have undergone percutaneous endoscopic gastrostomy(PEG)tube *** has not been reported in patients who underwent a PEG insertion via the radiological or introducer *** describe a novel case presentation of metastatic disease in a patient who underwent PEG placement via the introducer(Russell)technique which,to the best of our knowledge,has not not previously been *** *** patient was a 37-year-old Malay woman who developed metastatic squamous cell carcinoma deposits in her stomach and liver one month after a gastrostomy tube was removed following the completion of treatment for oropharyngeal *** authors have advocated the use of alternative PEG insertion technique apart from the‘pull’technique to minimise the risk of tumour implantation from head and neck *** case report suggests that this risk is not totally eliminated when the PEG tube is inserted via the introducer technique.

关键词： endoscopic gastrostomy