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Journal of Advanced Ceramics 2016年第4期5卷 92-页

作者： bharathi ponraj Rajasekhar BHIMIREDDI K.B.R.VARMA Materials Research Centre Indian Institute of Science Bangalore-560012 India

Polymer nanocrystal composites were fabricated by embedding polyvinylidene fluoride (PVDF) with K0.5Na0.5NbO3 (KNN) nanocrystallites of different volume fraction using the hot-pressing technique. For comparison, PVDF–KNN microcrystal composites of the same compositions were also fabricated which facilitated the studies of the crystallite size (wide range) effect on the dielectric and piezoelectric properties. The structural, morphological, dielectric, and piezoelectric properties of these nano and micro crystal composites were investigated. The incorporation of KNN fillers in PVDF at both nanometer and micron scales above 10 vol% resulted in the formation of polar β-form of PVDF. The room temperature dielectric constant as high as 3273 at 100 Hz was obtained for the PVDF comprising 40 vol% KNN nanocrystallites due to dipole–dipole interactions (as the presence of β-PVDF is prominent), whereas it was only 236 for the PVDF containing the same amount (40 vol%) of micron-sized crystallites of KNN at the same frequency. Various theoretical models were employed to predict the dielectric constants of the PVDF–KNN nano and micro crystal composites. The PVDF comprising 70 vol% micron-sized crystallites of KNN exhibited a d33 value of 35 pC/N, while the nanocrystal composites of PVDF–KNN did not exhibit any piezoelectric response perhaps due to the unrelieved internal stress within each grain, besides the fact that they have less domain walls.

关键词： polyvinylidene fluoride (PVDF) K 0.5 Na 0.5 NbO 3 (KNN) composites β -PVDF nanocrystallites

Investigation of Single and Multiple Mutations Prediction Using Binary Classification Approach

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Intelligent Automation & Soft Computing 2023年第4期36卷 1189-1203页

作者： T.Edwin ponraj J.Charles Department of Computer Applications Noorul Islam Centre for Higher EducationKumaracoil629180India Department of Software Engineering Noorul Islam Centre for Higher EducationKumaracoil629180India

The mutation is a critical element in determining the proteins’stability,becoming a core element in portraying the effects of a drug in the pharmaceutical *** wet laboratory tests to provide a better perspective on protein mutations is expensive and time-intensive since there are so many potential muta-tions,computational approaches that can reliably anticipate the consequences of amino acid mutations are *** work presents a robust methodology to analyze and identify the effects of mutation on a single protein ***,the context in a collection of words is determined using a knowledge graph for feature selection *** proposed prediction is based on an easier and sim-pler logistic regression inferred binary classiﬁcation *** approach can able to obtain a classiﬁcation accuracy(AUC)Area Under the Curve of 87%when randomly validated against experimental energy ***,for each cross-fold validation,the precision,recall,and F-Score are *** results support the validity of our strategy since it performs the vast majority of prior studies in this domain.

关键词： Proteins data science mutation analysis random forest neighbor proteins single and double mutations

Taurine in semen extender modulates post–thaw semen quality,sperm kinematics and oxidative stress status in mithun(Bos frontalis)spermatozoa

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Asian pacific Journal of Reproduction 2022年第1期11卷 35-43页

作者： Perumal ponraj Kobu Khate Kezhavituo Vupru ICAR-National Research Centre on Mithun MedziphemaNagaland–797106India ICAR-Central Island Agricultural Research Institute Port Blair744105Andaman and Nicobar IslandsIndia

Objective:To assess the effect of taurine on post-thaw semen quality parameters,sperm kinematics,antioxidant and oxidative stress profiles and sperm cholesterol efflux in mithun(Bos frontalis).Methods:A total of 50 ejaculates(n=25 samples)were selected based on biophysical *** sample was split into four equal aliquots after dilution with the Tris-citrate-glycerol ***Ⅰ,Ⅱ,ⅢandⅣcontained 0 mM(the control),25 mM,50 mM and 100 mM of taurine,***-thawed samples were analysed for motility parameters(progressive forward and in bovine cervical mucus penetration test),kinetic and velocity parameters by computer-assisted sperm analyzer,viability,sperm and nuclear abnormalities,acrosome integrity,plasma membrane and nuclear integrities,sperm enzymatic leakage and biochemical(sperm cholesterol and oxidative stress)***:The extender containing 50 mM taurine led to a significant enhancement in viability,acrosomal integrity,plasma membrane integrity,motility(progressive and in cervical mucus),and sperm cholesterol content and notably reduced sperm morphological and nuclear abnormalities,and leakage of intracellular enzymes compared to other taurine treated and untreated control groups(P<0.05).Moreover,in addition to significant improvement in kinetic and velocity profiles,50 mM taurine protected the integrity of acrosome and biochemical membranes than in the untreated control and other taurine treated *** of 50 mM taurine held a clear advantage over the control or 25 mM or 100 mM taurine in cryopreservation of mithun ***:Taurine(50 mM)supplementation in semen extender can be effectively utilized to reduce oxidative stress and improve post-thaw semen quality in mithun.

关键词： Antioxidants Cryopreservation Kinematic profiles Mithun Oxidative stress Spermatozoa Taurine Semen quality Post-thaw

Exogenous gonadotropin releasing hormone (GnRH) modulates scrotal and testicular biometrics, libido, endocrinological and heamatological profiles in Ganjam goat under humid tropical coastal ecosystem of Odisha

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Asian pacific Journal of Reproduction 2022年第6期11卷 285-291页

作者： Jibanjyoti Nayak Anil Kumar Nahak Purna Chandra Mishra Dillip Kumar Karna Chinmoy Mishra Perumal ponraj OUAT-College of Veterinary Science and Animal Husbandry BhubaneswarOdishaIndia ICAR-Central Island Agricultural Research Institute Port Blair-744105Andaman and Nicobar IslandsIndia

Objective:To assess the effect of exogenous gonadotropin releasing hormone(GnRH)in libido,scrotal and testicular biometrics,endocrinological and heamatological profiles of Ganjam goat buck during winter and pre-monsoon ***:Forty eight healty Ganjam goat bucks of 3-4 years old were equally divided into the control and treatment *** control group received distilled water as placebo,while the treatment group received GnRH injection(4μg Buserelin acetate/mL)once a week for four *** weight,scrotal circumference and testicular parameters(testicular volume,testicular weight and testis index),endocrinological profiles[follicle stimulating hormone(FSH),luteinizing hormone(LH),and testosterone],sex behavioural profiles(libido score,mating ability score,and sex behavioural score)and heamatological profiles(red blood cells,white blood cells,haemoglobin,and packed cell volume)were ***:The libido,scrotal and testicular biometrics,and endocrinological profiles significantly differed between the control and GnRH-treated bucks within and between the seasons within the two groups(P<0.05).Body weight,scrotal circumference,testicular volume,testicular weight,testis index,FSH,LH,testosterone,libido score,mating ability score,sex behavioural score,red blood cells,haemoglobin and packed cell volume were significantly higher in the GnRH-treated bucks compared to the control bucks in pre-monsoon and winter seasons(P<0.05).Body weight,scrotal circumference,testicular volume,testicular weight,testis index,FSH,LH,testosterone,libido score,mating ability score,sex behavioural score,red blood cell counts(in treatment),and haemoglobin were significantly higher in pre-monsoon compared to winter season in the experimental groups(P<0.05).The white blood cell counts neither differed between seasons nor between the two ***:Exogenous GnRH supplementation and pre-monsoon season have higher beneficial effects in improvement of endocrinological profi

关键词： Hormone GnRH Ganjam goat Libido Scrotal parameters Testicular parameters

Season modulates endocrinological profiles and sex behavioural characteristics in indigenous male goats under tropical humid island ecosystem

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Asian pacific Journal of Reproduction 2022年第4期11卷 183-192页

作者： Perumal ponraj Jai Sunder Arun Kumar De Rafeeque Rahman Alyethodi Purna Chandra Mishra Sneha Bhowmick Debasis Bhattacharya ICAR-Central Island Agricultural Research Institute Port Blair-744105Andaman and Nicobar IslandsIndia Department of ARGO OUAT-College of Veterinary ScienceBhubaneswar-751003OdishaIndia

Objective:To measure the seasonal effect on endocrinological profiles and sex behavioural profiles during rainy and dry summer seasons in male Andaman local goat in Andaman and Nicobar Islands,***:Ten adult male Andaman local goats were selected from the goat breeding farm,ICAR-Central Island Agricultural Research Institute,Port Blair,Andaman and Nicobar Islands,*** profiles such as follicle stimulating hormone(FSH),luteinizing hormone(LH),testosterone,thyroid stimulating hormone(TSH),triiodothyronine(T3),thyroxine(T4),cortisol and prolactin were analysed with enzyme-linked immunosorbent assay *** behavioural profiles such as libido score,mating ability score and sex behavioural score were measured during rainy and dry summer seasons in male Andaman local ***:Endocrinological profiles as well as sex behavioural profiles differed significantly between rainy season and dry summer season(P<0.05).The levels of FSH,LH,testosterone,TSH,T3,and T4 were significantly higher in rainy season than in dry summer season whereas cortisol and prolactin were significantly higher in dry summer season than in rainy season(P<0.05).The ratio of T3:T4 was significantly higher in rainy season than in dry summer ***,libido score,mating ability score and sex behavioural score were significantly higher in rainy season than in dry summer season(P<0.05).Conclusions:Rainy season has significantly higher beneficial effects than summer season on reproduction and artificial breeding programmes in semi-intensive management of goat under the tropical humid island ecosystem in Andaman and Nicobar Islands.

关键词： Andaman and Nicobar Islands Hormone Goat Libido Season Tropical humid island Island ecosystem Rain fall Temperature humidity index Light hour

Prevalence of various pathological conditions in female buffaloes (Bubalus bubalis)

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Asian pacific Journal of Reproduction 2017年第2期6卷 58-67页

作者： Perumal ponraj Sukkum Chang Nakulan V Rajesh Muthusamy Veeraselvam Kalpana Devi Rajesh ICAR-National Research Centre on Mithun MedziphemaNagaland-797 106India TANUVAS-Veterinary University Training and Research Centre Ramanathapuram-623 503India TANUVAS-Veterinary College and Research Institute OrathanaduThanjavur-614 625India A.V.V.M.Sri Pushpam College Thanjavur-613 503India

The present review article has described the prevalence of various pathological conditions of reproductive system of female buffaloes starting from ovary to vulva and vagina. Various pathological conditions were analyzed and tabulated as the total number of animal examined, number of the animals showed pathological lesions, percentage of animal showed various pathological lesions and percentage of individual pathological lesion in different parts of reproductive system of female buffaloes. The incidence of disorders of female genital organs of buffaloes has been reported by various authors at various percentages in different countries. The incidence of pathological conditions was recorded in clinically infertile cows after slaughtering or from apparently healthy buffaloes slaughtered for human consumption and/or based on postmortem examination. This review is comprehensively covering pathological conditions of female buffalo hitherto which was not previously described at one place. This review will provide a comprehensive knowledge about the prevalence of different pathological condition of different parts of reproductive tract of female buffaloes. The review has six numbers of tables described about the various pathological conditions from ovary to vulva and vagina in female buffaloes. The present review article will be very useful to the buffalo farmers, buffalo breeders and researchers are working in buffalo reproduction & breeding and pathology.

关键词： Female buffaloes Reproductive system Pathological conditions Infertility Incidence/Percentage

Human Monoclonal Antibodies as Candidate Therapeutics Against Emerging Viruses and HIV-1

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Virologica Sinica 2013年第2期28卷 71-80页

作者： Zhongyu Zhu ponraj Prabakaran Weizao Chen Christopher C.Broder Rui Gong Dimiter S.Dimitrov Protein Interactions Group National Cancer Institute National Institutes of Health Basic Research Program Science Applications International Corporation-Frederick Inc. Department of Microbiology and Immunology Uniformed Services University Center for Emerging Infectious Diseases Wuhan Institute of Virology Chinese Academy of Sciences

More than 40 monoclonal antibodies (mAbs) have been approved for a number of disease indications with only one of these (Synagis) - for a viral disease, and not for therapy but for prevention. However, in the last decade novel potent mAbs have been discovered and characterized with potential as therapeutics against viruses of major importance for public health and biosecurity including Hendra virus (HeV), Nipah virus (NiV), severe acute respiratory syndrome coronavirus (SARS-CoV), Ebola virus (EBOV), West Nile virus (WNV), influenza virus (IFV) and human immunodeficiency virus type 1 (HIV-1). Here, we review such mAbs with an emphasis on antibodies of human origin, and highlight recent results as well as technologies and mechanisms related to their potential as therapeutics.

关键词：人类免疫缺陷病毒单克隆抗体病毒性疾病 HIV-1 治疗 SARS-CoV 呼吸系统综合症西尼罗河病毒

Further Results on Pair Sum Labeling of Trees

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Applied Mathematics 2011年第10期2卷 1270-1278页

作者： Raja ponraj Jeyaraj Vijaya Xavier Parthipan 不详

Let G be a (p,q) graph. An injective map f:V(G)→﹛±1,±2,...±p﹜is called a pair sum labeling if the induced edge function, fe:E(G)→Z-﹛0﹜defined by fe(uv)=f(u)+f(v) is one-one and fe(E(G)) is either of the form {±k1,±k2,...,±kq/2} or {±k1,±k2,...,±kq-1/2}∪{kq+1/2} according as q is even or odd. A graph with a pair sum labeling is called a pair sum graph. In this paper we investigate the pair sum labeling behavior of some trees which are derived from stars and bistars. Finally, we show that all trees of order nine are pair sum graphs.

关键词： Path Star Bistar Tree

Mean Cordial Labeling of Graphs

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Open Journal of Discrete Mathematics 2012年第4期2卷 145-148页

作者： Raja ponraj Muthirulan Sivakumar Murugesan Sundaram Department of Mathematics Sri Paramakalyani College Alwarkurchi India Department of Mathematics Unnamalai Institute of Technology Kovilpatti India

Let f be a map from V(G) to . For each edge uv assign the label . f is called a mean cordial la- beling if and , , where and denote the number of vertices and edges respectively labelled with x ( ). A graph with a mean cordial labeling is called a mean cor- dial graph. We investigate mean cordial labeling behavior of Paths, Cycles, Stars, Complete graphs, Combs and some more standard graphs.

关键词： Path Star Complete Graph Comb

Self-assembled V2O5 interconnected microspheres produced in a fish-water electrolyte medium as a high- performance lithium-ion-battery cathode

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Nano Research 2015年第11期8卷 3591-3603页

作者： Md Mokhlesur Rahman Abu Z. Sadek Irin Sultana Mateti Srikanth Xiujuan J. Dai Matthew R. Field Dougal G. McCulloch Sri Balaji ponraj Ying Chen Institute for Frontier Materials Deakin University Waurn Ponds VIC 3216 Australia Melbourne Centre for Nanofabrication 151 Wellington Rd Clayton VIC 3168 Australia School of Applied Sciences Applied Physics RMIT University Melbourne VIC 3001 Australia

V 2 由极端长的 nanobelts 组成的 O 5 被采用与退火相结合的一个常规阳极化过程以一个环境友好方法综合。因为它不要求任何另外的化学药品或试剂，合成过程简单、便宜。商业鱼水被用作电解质媒介第一次阳极化钒陪衬。电子显微镜学调查... 详细信息

V 2 由极端长的 nanobelts 组成的 O 5 被采用与退火相结合的一个常规阳极化过程以一个环境友好方法综合。因为它不要求任何另外的化学药品或试剂，合成过程简单、便宜。商业鱼水被用作电解质媒介第一次阳极化钒陪衬。电子显微镜学调查表明每条带与在他们之间的空间由众多的 nanofibers 组成。因此，这新奇 nanostructure 在电气化学的操作期间表明许多突出的特征。这结构阻止活跃材料的自我聚集并且充分由维持在活跃材料，传导性的添加剂，和电解质之间的一个大有效接触区域利用活跃材料的优点，它是为大多数 nanomaterials 的关键挑战。电极与 227 mAhub 的一个稳定的分泌物能力展出有希望的电气化学的性能 > 49 -based synergistic tri 形式的治疗根除了异种皮移植肿瘤和没有复发被观察在以内一 9 月列在后面起来。而且，钨元素的强壮的 X 光检查变细能力(Z = 74， 4.438 厘米 2????  ??  ?? 佦 ? 畳 ?? 猯扵￣？？

关键词：锂离子电池性能稳定电解质 V2O5 阴极微球水作鱼塘