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Chinese Journal of Electronics 2024年第1期33卷 43-57页

作者： Brou bernard Ehui Chen CHEN Shirui WANG Hua GUO Jianwei LIU School of Cyber Sciences and Technology Beihang University State Key Laboratory of Software Development Environment Beihang University Sino-French Engineering School Beihang University Beihang Hangzhou Innovation Institute Yuhang

Because of the increasing number of threats in the IoT cloud, an advanced security mechanism is needed to guard data against hacking or attacks. A user authentication mechanism is also required to authenticate the user accessing the cloud services. The conventional cryptographic algorithms used to provide security mechanisms in cloud networks are often vulnerable to various cyber-attacks and inefficient against new attacks. Therefore,developing new solutions based on different mechanisms from traditional cryptography methods is required to protect data and users’ privacy from attacks. Different from the conventional cryptography method, we suggest a secure mutual authentication protocol based on the visual cryptography technique in this paper. We use visual cryptography to encrypt and decrypt the secret images. The mutual authentication is based on two secret images and *** user requests the ticket from the authentication server(AS) to obtain the permission for accessing the cloud services. Three shared secret keys are used for encrypting and decrypting the authentication process. We analyze the protocol using the Barrows-Abadi-Needham(BAN)-logic method and the results show that the protocol is robust and can protect the user against various attacks. Also, it can provide a secure mutual authentication mechanism.

关键词： Visualization Cloud computing Data privacy Protocols Biometrics (access control) Authentication Resists

Spirotetramat reduces fitness of the spotted-wing Drosophila,Drosophila suzukii

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Insect Science 2024年第4期31卷 1222-1230页

作者： Jing Yang Justin Flaven-Pouchon Yiwen Wang bernard moussian Section of Animal Genetics Interfaculty Institute of Cell BiologyUniversity of TübingenTübingenGermany School of Pharmaceutical Science and Technology Tianjin UniversityTianjinChina INRAE CNRSUniversitéCôte d'AzurInstitut Sophia AgrobiotechSophia AntipolisFrance

With climate change,the spotted-wing Drosophila(SWD,Drosophila suzukii)invades a great number of fruit production regions worldwide.A plethora of insecticides are being applied for management of this *** expected,SWD develops resistance against some potent insecticides or is rather insensitive to some ***,there is an urgent need to identify and characterize alternative insecticides to control SWD ***,we have studied the effects of the orally applied inhibitor of the fatty acid synthesis pathway spirotetramat on SWD fitness with respect to fecundity and surface barrier function at different *** our experiments,we applied spirotetramat mixed with baker's yeast and showed that females and males were not repelled by effective concentrations of this *** found that spirotetramat,by trend,lowers egg numbers laid by fed *** eggs rapidly desiccate,and only a few larvae *** is lethal to larvae and reduces survival of adult flies under low-humidity *** together,based on our data,we propose to use yeast supplemented with spirotetramat and additional SWD-specific attractants in traps in non-crop areas in order to eradicate SWD populations before they infest crop production sites.

关键词： desiccation Drosophila suzuki insecticide lipids

monitoring absolute vertical land motions and absolute sea-level changes from GPS and tide gauges data over French Polynesia

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Geodesy and Geodynamics 2024年第1期15卷 13-26页

作者： Xianjie Li Jean-Pierre Barriot bernard Ducarme marania Hopuare Yidong Lou Geodesy Observatory of Tahiti University of French PolynesiaFaa'a 98702French Polynesia Catholic University of Louvain Georges Lemaître Centre for Earth and Climate Research(ELI)1348 Louvain-la-NeuveBelgium GNSS Research Center Wuhan UniversityWuhan 430079China State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhan 430079China

In this study,we estimate the absolute vertical land motions at three tidal stations with collocated Global Navigation Satellite System(GNSS)receivers over French Polynesia during the period 2007-2020,and obtain,as ancillary results,estimates of the absolute changes in sea level at the same *** verify our processing approach to determining vertical motion,we first modeled vertical motion at the International GNSS Service(IGS)THTI station located in the capital island of Tahiti and compared our estimate with previous independent determinations,with a good *** obtained the following estimates for the vertical land motions at the tide gauges:Tubuai island,Austral Archipelago-0.92±0.17 mm/yr,Vairao village,Tahiti Iti:-0.49±0.39 mm/yr,Rikitea,Gambier Archipelago-0.43±0.17 mm/*** absolute variations of the sea level are:Tubuai island,Austral Archipelago 5.25±0.60 mm/yr,Vairao village,Tahiti Iti:3.62±0.52 mm/yr,Rikitea,Gambier Archipelago 1.52±0.23 mm/*** discuss these absolute values in light of the values obtained from altimetric measurements and other means in French Polynesia.

关键词： GPS Tide gauges Sea level changes Vertical land motion

Functional trait composition of carabid beetle communities predicts prey suppression through both mass ratio and niche complementarity mechanisms

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Insect Science 2024年第2期31卷 562-574页

作者： Abdelhak Rouabah Francoise Lasserre-Joulin Sylvain Plantureux Simon Taugourdeau bernard Amiaud Universite de Loraine INRAELAENancyF-54000France UmR SELmET CIRADINRAEInstitut AgroUniversite de MontpellierMontpellier34000France CIRAD UMR SELMET-PPZSDakarSéenegal UmR Siva Universitéde LorraineAgroParisTechINRAEVandoeuvreLes Nancy54506France

Several components of predator functional diversity have been hypothesized to influence prey suppression through either niche complementarity or mass ratio ***,most studies have used a functional group approach when assessing the role of these predators in ecosystem *** adopting a trait-based approach,we evaluated the relative contributions of carabid diversity components in predicting prey *** results highlight the importance of both taxonomic and functional diversity components of carabids as key drivers of prey *** suppression was best predicted by carabid densities,with the dominance of Poecilus cupreus potentially driving the positive effect of community total abundance through the mass ratio *** suppression increased with increasing the density of large *** addition,carabid eye diameter and antennal length were key functional traits for predicting prey ***,prey suppression increased with increasing carabid functional richness following the niche complementarity *** contrast to functional richness,functional evenness and functional divergence of carabid communities were weakly correlated with prey *** identifying which diversity components of carabid communities contribute the most to increase prey suppression,our results can guide efforts aiming to predict the relationship between diversity of these predators and ecosystem functioning.

关键词： abundance distribution biological control body size ecosystem function functional richness predator-prey interactions

Role of CYP311A1 in wing development of Drosophila melanogaster

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Insect Science 2024年第3期31卷 748-758页

作者： Xubo Zhang mengqi Liu Andi Cheng bernard moussian Jianzhen Zhang Wei Dong Shanxi Key Laboratory of Nucleic Acid Biopesticides Institute of Applied BiologyShanxi UniversityTaiyuanChina College of Life Science Shanxi UniversityTaiyuanChina INRAE CNRSInstitut Sophia AgrobiotechSophia AntipolisUniversite Cote d'AzurNiceFrance

Lipid homeostasis is crucial for growth and development of *** cytochrome P450 monooxygenases(CYPs)are involved in lipid *** function of Cyp3llal in the anterior midgut as a regulator of phosphatidylethanolamine(PE)metabolism in Drosophila melanogaster has been demonstrated,as depletion of Cyp31lal caused larval growth arrest that was partially rescued by supplying *** this study,we investigated the role of CYP311A1 in wing morphogenesis in *** the GAL4-UAS system,Cyp31lal was selectively knocked down in the wing disc.A deformed wing phenotype was observed in flies with reduced Cyp31lal *** and oil red O staining revealed a reduction of neutral lipids in the wing disc after the depletion of *** addition,we observed an enhanced sensitivity to Eosin Y penetration in the wings of Cyp31lal knocked-down ***,the reduction of CYP311A1 function in developing wings does not affect cell proliferation and apoptosis,but entails disordered Phalloidin or Cadherin distribution,suggesting an abnormal cell morphology and cell cortex structure in wing epithelial *** together,our results suggest that Cyp3llal is needed for wing morphogenesis by participating in lipid assembly and cell homeostasis.

关键词： apoptosis cell cortex cell proliferation Cyp31lal lipid wing

Template-free nanostructured particle growth via a one-pot continuous gradient nanoprecipitation

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Aggregate

Aggregate 2024年第1期5卷 409-418页

作者： Xie Cheng Shuai Wang Julien bernard François Ganachaud Xibo Yan School of Chemical Engineering and Technology Tianjin UniversityTianjinChina College of Food Science and Engineering Tianjin University of Science and TechnologyTianjinChina Universitéde Lyon CNRSUniversitéClaude Bernard Lyon 1INSA-LyonUniversitéJean MonnetUMR5223Ingénierie des Matériaux PolymèresVilleurbanne CedexFrance

Engineered nanoparticles have emerged as new types of materials for a wide range of applications from therapeutics to ***,fabricating nanomaterials presenting complex inner morphologies and shapes in a simple manner remains a great ***,we report the template-free one-pot continuous gradient nanoprecipitation of different types of non-compatible polymers to spontaneously form nanostructured *** continuous addition of antisolvent induces precipitation and(re)organization of polymer chains at the forming particle interface,ultimately and naturally developing complex inner morphologies and shapes while particle *** low-energy-cost bottom-up assembly approach applies to various functional polymers,possibly embedded with metal nanoparticles,for continuous growth into well-organized *** crosslinking of the particles and core removal allows both confirming the building process and leading to hollow or multivoid nanomaterials.

关键词： aggregation nanoprecipitation phase diagrams polymeric nanoparticles self-assembly

A randomized,controlled,open label non-inferiority trial of intravenous ferric carboxymaltose versus iron sucrose in patients with iron deficiency anemia in China

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Frontiers of medicine 2024年第1期18卷 98-108页

作者： Jie Jin Zhihua Ran Emanuele Noseda bernard Roubert matthieu marty Anna mezzacasa Udo michael Göring The First Affiliated Hospital Zhejiang University College of MedicineHangzhou310058China Renji Hospital Shanghai Jiao Tong University School of MedicineShanghai200025China Vifor Pharma Glattbrugg8152Switzerland

Iron deficiency(ID)and ID anemia(IDA)pose significant public health concerns in *** iron sucrose(IS)treatment is well-established in the country,ferric carboxymaltose(FCm)offers the advantage of higher doses and fewer *** open label,randomized,controlled,non-inferiority trial was conducted at multiple sites in China to compare the outcomes of FCm(maximum of 2 doses,500 or 1000 mg iron)and IS(up to 11 infusions,200 mg iron)treatments in subjects with *** primary endpoint was the achievement of hemoglobin(Hb)response(an increase of⩾2 g/dL from baseline)within 8 weeks,whereas secondary endpoints included changes in Hb,transferrin saturation,and serum ferritin *** the 371 randomized subjects,a similar percentage of subjects treated with FCm and IS achieved Hb-response(FCm 99.4%,IS 98.3%),thereby confirming the non-inferiority of FCm compared with IS(difference 1.12(−2.15,4.71;95%confidence interval(CI))).Furthermore,a significantly higher proportion of FCm-treated subjects achieved early Hb-response at Week 2(FCm 85.2%,IS 73.2%;difference 12.1(3.31,20.65;95%CI)).Additionally,the increase in TSAT and serum ferritin levels from baseline was significantly greater at all time points for FCm-treated *** safety profiles of FCm and IS were comparable,with the exception of transient hypophosphatemia and pyrexia,which are consistent with FCm’s known safety *** conclusion,FCm proves to be an efficacious treatment for IDA,providing faster Hb-response and correction of ID with fewer administrations than IS.

关键词： iron deficiency anemia intravenous iron ferric carboxymaltose iron sucrose Hb response early response

Bacterial plant pathogens affect the locomotor behavior of the insect vector:a case study of Citrus volkameriana-Triozae erytreae-Candidatus Liberibacter asiaticus system

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Insect Science 2024年第3期31卷 901-910页

作者： Arnaud Ameline Alain Karkach Thomas Denoirjean martial Grondin Florencia molinari Patrick Turpin Helene Delatte bernard Reynaud UmR CNRS 7058 EDYSAN(Ecologie et Dynamique des Systemes Anthropises) Universite de Picardie Jules VerneAmiensCedexFrance UmR PVBmT(Peuplements végétaux et bioagresseurs en milieu tropical) Universitéde la RéunionSaint PierreLa RéunionFrance

Plant pathogens can alter the behavior of their insect vectors as well as their survival and *** African psyllid,Trioza erytreae,is one of the vectors of Huanglongbing,a citrus disease caused mainly by"Candidatus Liberibacter asiaticus"(CLas).The purpose of this study was to characterize the effects of CLas on the psyllid,*** using Citrus volkamerina plants as the study *** study focused more specifically on the CLas effects prior to and after its acquisition by the psyllid *** results did not support the hypothesis that CLas effects psyllid probing behavior prior to acquisition;few differences were observed between uninfected *** feeding on CLas-infected versus control *** the other hand,compared to psyllids that had completed their development on control plants,the ones that had completed their development on a CLas-infected plant exhibited changes in their behavior(greater velocity),physiology(smaller mass)and biochemistry(lower water and lipid content).Altogether,our results confirm the existence of a marked postacquisition effect on the vector locomotor behavior and a minor preacquisition effect of CLas on the vector behavior,which can be partially explained by physiological and biochemical changes.

关键词： electrical penetration graph Huanglongbing locomotory behavior lipid biomass probing behavior vector manipulation

Characteristics of patients with Wilson disease in the United States: An insurance claims database study

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World Journal of Hepatology 2024年第5期16卷 791-799页

作者： Thomas Daniel-Robin Pradeep Kumar bernard Benichou Jean-Philippe Combal Vivet Therapeutics Paris 75008France Clarivate Noida 201301Uttar PradeshIndia

BACKGROUND Wilson disease(WD)is a progressive,potentially fatal degenerative disease affecting the liver and central nervous *** its low prevalence,collecting data on large cohorts of patients with WD is *** insur-ance claims databases provide powerful tools to collect retrospective data on large numbers of patients with rare *** To describe patients with WD in the United States,their treatment and clinical outcome,using a large insurance claims *** This retrospective,longitudinal study was performed in the Clarivate Real-World Data Product *** patients with≥2 claims associated with an Interna-tional Classification of Diseases 10(ICD-10)diagnostic code for WD(E83.01)between 2016 and 2021 were included and followed until death or study *** were divided into two groups by whether or not they were documented to have received a specific treatment for *** manifestations,hospital-isations,liver transplantation and death were *** Overall,5376 patients with an ICD-10 diagnostic code for WD were *** mean age at inclusion was 41.2 years and 52.0%were men.A specific WD treatment was documented for 885 patients(15.1%),although the number of patients taking zinc salts may be underestimated due to over the counter *** inclusion,the mean age of patients with a documented treatment was 36.6±17.8 years vs 42.2±19.6 years in those without a documented *** follow-up,273 patients(5.1%)*** with the American general population,the standardised mortality ratio was *** proportion of patients with a documented WD-specific treatment who died during follow-up was 4.0%and the mean age at death 52.7 *** Patients treated for WD in the United States had an excess early mortality compared with the American *** findings indicate that there is a significant unmet need for effective treatment for WD in the United States.

关键词： Wilson disease mortality Treatment Copper chelators Zinc acetate United States