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Comparison of body mass index, anti-müllerian hormone and insulin resistance parameters among different phenotypes of polycystic ovary syndrome

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Gynecology and Obstetrics Clinical Medicine 2022年第4期2卷 164-170页

作者： Türkan Gürsu Alper Eraslan berk angun University of Health Sciences Turkey Zeynep Kamil Maternity and Children's Training and Research HospitalDepartment of Obstetrics and GynecologyIstanbulTurkey Dunya IVF Center KyreniaCyprus Department of Reproductive Endocrinology and InfertilityTurkey

Background:Diagnosis of polycystic ovary syndrome(PCOS)depends on 2003 Rotterdam *** to these criteria there are four possible combinations resulting in various *** aimed(i)to confirm that the levels of body mass index(BMI),anti-müllerian hormone(AMH)levels and insulin resistance(IR)are higher in PCOS patients and higher in phenotype-A among PCOS patients,and(ii)to determine cut-off values for the diagnosis of PCOS and *** and methods:This study was conducted in an IVF Center,between November 2019 and January *** of infertile women participating in the study was evaluated *** such as menstruation pattern,clinical hyperandrogenism,age,BMI,follicle stimulating hormone(FSH),luteinizing hormone(LH),estradiol,thyroid stimulating hormone(TSH),prolactin,AMH,dehydroepiandrosterone sulphate(DHEA-S),fasting blood glucose,fasting insulin levels,antral follicle counts(AFC)and ovarian volumes were recorded for each *** were grouped as PCOS and non-PCOS,and PCOS group was further divided into 4 subgroups according to their *** of infertile patients with PCOS patients were compared with infertile non-PCOS patients and PCOS phenotypes were compared among each ***:Data of 244 infertile patients was included in the ***,AMH,AFC,and HOMA-IR were statistically higher in PCOS patients,compared to non-PCOS *** found the AMH level of>3.105 ng/ml to be having 90.8%sensitivity and 90%specificity to diagnose a patient as *** different phenotypes,also BMI,AMH,and insulin resistance index(HOMA-IR)levels were significantly higher in infertile PCOS phenotype-A when compared to other three phenotypes(p:0.003,p:0.000,and p:0.000,respectively).The AMH cut-off value to estimate phenotype-A was found as 6.095 ng/ml with 69.2%sensitivity and 86.7%*** did not found threshold levels of BMI and HOMA-IR with high sensitivity to identify ***:Properly di

关键词： Polycystic ovarian syndrome Body mass index Anti-müllerian hormone Insulin resistance PCOS Phenotypes

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