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Exploring research on ecotechnology through artificial intelligence and bibliometric maps

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Environmental Science and Ecotechnology 2024年第5期21卷 405-412页

作者： Ricardo Ruiz-Sanchez Ricardo Arencibia-Jorge Julia Tagüena Jose Luis Jimenez-andrade Humberto Carrillo-Calvet Unidad Profesional Interdisciplinaria de Ingeniería Palenque(UPIIP) Instituto Politecnico NacionalPalenqueChiapasCP 29960Mexico Complexity Sciences Center National Autonomous University of MexicoCircuito Centro Cultural s/nCoyoacan04510Mexico CityMexico Institute of Renewable Energies(IER) National Autonomous University of MexicoPriv.Xochicalco s/nCol.CentroTemixcoMorelosCP 62580Mexico Faculty of Sciences National Autonomous University of MexicoCircuito Centro Cultural s/nCoyoacan04510Mexico CityMexico

Ecotechnology,quintessential for crafting sustainable socio-environmental strategies,remains tantalizingly *** analysis,steered by the nuances of machine learning and augmented by bibliometric insights,delineates the expansive terrain of this domain,elucidates pivotal research themes and conundrums,and discerns the vanguard nations in this ***,we deftly connect our discoveries to the United Nations'2030 Sustainable Development Goals,thereby accentuating the profound societal ramifications of ecotechnology.

关键词： Ecotechnologies Bibliometrics Sustainable development goals Network analysis SOM neural networks

Temporal and spatial differentiation in microhabitat use: Implications for reproductive isolation and ecological niche specification

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Integrative Zoology 2016年第5期11卷 375-387页

作者： Amaël BORZÉE Jun Young KIM Marina andrade Martins DA CUNHA Donggeun Lee Eunchong SIN Sunmin OH Yoonjung YI Yikweon JANG Department of Life Sciences and Division of EcoScience Ewha Womans UniversitySeoulKorea Interdisciplinary Program of EcoCreative Ewha Womans UniversitySeoulKorea School of Biological Sciences Seoul National UniversityKorea

Niche differentiation enables ecologically similar species to coexist by lessening competition over food and/or shelters and may be critical for reproductive isolation between closely related species in close ***cause no extra traits need to evolve,spatial and temporal differentiation may readily take place to complement other isolating *** closely related treefrog species occur together in Korea:the endangered Hyla suweonensis and the widespread Hyla *** calls are differentiated,but it is unclear whether call difference is sufficient for reproductive *** tracked individuals of both species to study fine-scale differentiation in microhabitat use in the diel cycle of the breeding season using a harmonic direction *** male movement patterns of both species revealed spatial and temporal differentiation in microhabitat use for calling and resting during the breeding *** of both *** and *** occurred in all 5 microhabitats identified in this study:rice paddy,ground,buried,grass and *** treefrog species showed general similarities in calling from rice paddies and resting in grass and ***,*** moved into rice paddies and produced advertisement calls 3 h earlier than *** differences likely minimize contact between the species and provide an additional isolating *** addition,the activity of *** may be contributing to the decline of this species,as resting in grass would increase dangers from predatory birds and habitat disturbance.

关键词： harmonic direction finding hylid treefrog pre-mating isolation mechanisms spatial isolation temporal isolation

Prolonged cholestasis after raloxifene and fenofibrate interaction: A case report

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World Journal of Gastroenterology 2006年第32期12卷 5244-5246页

作者： M Isabel Lucena Raúl J andrade Luis Vicioso F Jesús González Ketevan Pachkoria Beatriz García-Mu(n|~)oz Clinical Pharmacology Service Virgen de la Victoria University Hospital School of MedicineMalagaSpain Liver Unit Gastroenterology Service Virgen de la Victoria University HospitalSchool of MedicineMálagaSpain Department of Pathology Virgen de la Victoria University Hospital School of MedicineMálagaSpain Institute of Biopathology and Regenerative Medicine University of Granada Spain Clinical Pharmacology Service Virgen de la Victoria University Hospital School of MedicineMálagaSpain

Assigning causality in drug-induced liver injury is challenging particularly when more than one drug could be responsible. We report a woman on long-term therapy with raloxifen who developed acute cholestasis shortly after starting fenofibrate. The picture evolved into chronic cholestasis. We hypothesized that an interaction at the metabolic level could have triggered the presentation of hepatotoxicity after a very short time of exposure to fenofibrate in this patient. The findings of an overexpression of vascular endothelial growth factor in the liver biopsy suggest that angiogenesis might play a role in the persistance of toxic cholestasis.

关键词： Raloxifene Fenofibrate Drug-drug interactions Hepatotoxicity Causality assessment

Cytomegalovirus frequency in neonatal intrahepatic cholestasis determined by serology, histology, immunohistochemistry and PCR

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World Journal of Gastroenterology 2009年第27期15卷 3411-3416页

作者： Maria Angela Bellomo-Brandao Paula D andrade Sandra CB Costa Cecilia AF Escanhoela Jose Vassallo Gilda Porta Adriana MA De Tommaso Gabriel Hessel Department of Pediatrics Faculty of Medical Sciences State University of Campinas (UNICAMP)Campinas-SP 13083-970 Brazil Department of Internal Medicine Faculty of Medical Sciences State University of Campinas (UNICAMP)Campinas-SP 13083-970 Brazil Department of Pathology Faculty of Medical Sciences State University of Campinas (UNICAMP) Campinas-SP 13083-970 Brazil Department of Pediatrics Children's Institute of Medical School of the University of So Paulo (USP) So Paulo-SP 05403-000 Brazil

AIM: To determine cytomegalovirus (CMV) frequency in neonatal intrahepatic cholestasis by serology, histological revision (searching for cytomegalic cells), immunohistochemistry, and polymerase chain reaction (PCR), and to verify the relationships among these ***: The study comprised 101 non-consecutive infants submitted for hepatic biopsy between March 1982 and December 2005. Serological results were obtained from the patient's f iles and the other methods were performed on paraffin-embedded liver samples from hepatic biopsies. The following statistical measures were calculated: frequency, sensibility, specif ic positive predictive value, negative predictive value, and ***: The frequencies of positive results were as follows: serology, 7/64 (11%); histological revision, 0/84; immunohistochemistry, 1/44 (2%), and PCR, 6/77 (8%). Only one patient had positive immunohistochemical fi ndings and a positive PCR. The following statistical measures were calculated between PCR and serology: sensitivity, 33.3%; specificity, 88.89%; positive predictive value, 28.57%; negative predictive value, 90.91%; and accuracy, 82.35%. CONCLUSION: The frequency of positive CMV varied among the tests. Serology presented the highest positive frequency. When compared to PCR, the sensitivity and positive predictive value of serology were low.

关键词： Cytomegalovirus Hepatitis Neonatal Cholestasis Liver Children Immunohistochemistry Polymerase chain reaction

Targeting galectin-3 to counteract spike-phase uncoupling of fast-spiking interneurons to gamma oscillations in Alzheimer’s disease

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Translational Neurodegeneration 2023年第1期12卷 801-823页

作者： Luis Enrique Arroyo-García Sara Bachiller Rocío Ruiz Antonio Boza-Serrano Antonio Rodríguez-Moreno Tomas Deierborg Yuniesky andrade-Talavera AndréFisahn Neuronal Oscillations Laboratory Division of NeurogeriatricsCenter for Alzheimer ResearchDepartment of NeurobiologyCare Sciences and SocietyKarolinska Institutet17164 SolnaSweden Experimental Neuroinflammation Laboratory Department of Experimental Medical ScienceLund UniversityBMC B1122184 LundSweden Clinical Unit of Infectious Diseases Microbiology and ParasitologyInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of Biochemistry and Molecular Biology University of SevilleCalle Profesor García González Nº241012 SevilleSpain Laboratory of Cellular Neuroscience and Plasticity Department of PhysiologyAnatomy and Cellular BiologyUniversidad Pablo de OlavideCarretera de Utrera Km-141013 SevilleSpain Department of Biosciences and Nutrition NeoKarolinska Institutet14183 HuddingeSweden

Background Alzheimer’s disease(AD)is a progressive multifaceted neurodegenerative disorder for which no disease-modifying treatment *** is central to the pathology progression,with evidence suggesting that microglia-released galectin-3(gal3)plays a pivotal role by amplifying neuroinflammation in ***,the possible involvement of gal3 in the disruption of neuronal network oscillations typical of AD remains *** Here,we investigated the functional implications of gal3 signaling on experimentally induced gamma oscillations ex vivo(20-80 Hz)by performing electrophysiological recordings in the hippocampal CA3 area of wild-type(WT)mice and of the 5×FAD mouse model of *** addition,the recorded slices from WT mice under acute gal3 application were analyzed with RT-qPCR to detect expression of some neuroinflammation-related genes,and amyloid-β(Aβ)plaque load was quantified by immunostaining in the CA3 area of 6-month-old 5×FAD mice with or without Gal3 knockout(KO).Results Gal3 application decreased gamma oscillation power and rhythmicity in an activity-dependent manner,which was accompanied by impairment of cellular dynamics in fast-spiking interneurons(FSNs)and pyramidal *** found that the gal3-induced disruption was mediated by the gal3 carbohydrate-recognition domain and prevented by the gal3 inhibitor TD139,which also prevented Aβ42-induced degradation of gamma ***-more,the 5×FAD mice lacking gal3(5×FAD-Gal3KO)exhibited WT-like gamma network dynamics and decreased Aβplaque *** We report for the first time that gal3 impairs neuronal network dynamics by spike-phase uncoupling of FSNs,inducing a network performance ***,our findings suggest gal3 inhibition as a potential therapeutic strategy to counteract the neuronal network instability typical of AD and other neurological disorders encompassing neuroinflammation and cognitive decline.

关键词： Galectin-3 Gamma oscillations Neuronal network dynamics Fast-spiking interneurons Alzheimer’s disease models Neuroinflammation TD139 Hippocampus

Effects of drying process on total phenolics,antioxidant activity and flavonoid contents of common Mediterranean herbs

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International Journal of Agricultural and Biological Engineering 2015年第2期8卷 145-150页

作者： Taha M.Rababah Muhammad Al-u'datt Mohammad Alhamad Majdi Al-Mahasneh Khalil Ereifej Juan andrade Bayan Altarifi Ali Almajwal Wade Yang Faculty of Agriculture Jordan University of Science and TechnologyIrbid 22110Jordan Faculty of Engineering Jordan University of Science and TechnologyIrbid 22110Jordan Department of Food Science and Human Nutrition University of Illinois at Urbana-ChampaignUrbana Illinois 61801USA Department of Community Health Sciences College of Applied Medical SciencesKing Saud UniversityRiyadh 11451Saudi Arabia Department of Food Science and Human Nutrition University of FloridaGainesville Florida 32611USA

Four different fresh and dried herb species(sage,thyme,mint and lemonbalm)were evaluated to study the effect of drying process on the total phenolics,antioxidant activity,flavonoid contents and color *** mint had the highest contents of total phenolics(335.4 mg GAE/100 g),whereas lower levels were respectively found in sage(316.4 mg GAE/100 g)followed by lemonbalm(303.2 mg GAE/100 g)and thyme(299.2 mg GAE/100 g).Dry processing significantly decreased the phytochemical contents of all investigated *** to air drying,total phenolics,antioxidant activity and flavonoids content in herbs decreased apparently by oven *** mint had the highest antioxidant activity(87.46%)and flavonoids content(298.51 mg CE/100 g),while the fresh sage,thyme and lemonbalm were found to have antioxidant activity values of 86.81%,86.56% and 85.26%,*** showed that air drying herbs contained more total phenolics,antioxidant activity,and flavonoids than oven drying herbs.

关键词： Herbs drying process antioxidant activity flavonoids

Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: Is there still a role for these drugs?

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World Journal of Gastroenterology 2006年第31期12卷 5078-5080页

作者： Carmen Verge M Isabel Lucena Enrique López-Torres M José Puche-García Enrique Fraga Manuel Romero-Gomez Raúl J andrade Clinical Pharmacology ServiceVirgen de la Victoria University Hospital School of MedicineMálagaSpain Gastroenterology ServiceUniversity Hospital Reina Sofia CórdobaSpain Gastroenterology ServiceUniversity Hospital Virgen de Valme SevillaSpain Liver UnitDepartment of Gastroenterology University HospitalMálagaSpain

Disulfiram and calcium carbimide are two alcohol deterrants widely used in alcoholism treatment, however, there exist great concerns over their safety. Reports on hepatotoxicity, mainly related to disulfiram therapy, have been published. The hepatotoxic potential of calcium carbimide is less well characterized. Here, we describe four cases of liver damage related to this therapeutic group that were submitted to a Registry of hepatotoxicity and point out the limitations that we face when prescribing these compounds. A reassessment of the role of these compounds in the management of alcohol dependence is clearly needed.

关键词： Calcium carbimide Disulfiram Hepatotoxicity

Chitosan and Carboxymethylchitosan as High Turbidity Water Biocoagulants

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Journal of Renewable Materials 2020年第11期8卷 1489-1504页

作者： Raimundo N.Lima Júnior João L.I.O.Almeida Jones de andrade Flávia O.M.S.Abreu Natural Sciences Program State University of Ceará-UECEFortalezaCE 60714-903Brazil Physical-Chemistry Department Institute of ChemistryFederal University of Rio Grande do Sul-UFRGSPorto AlegreRS 91501-970Brazil

Biocoagulants emerges as a promising technology in water treatment,in order to exploit renewable and biodegradable *** present work aims to study the coagulant action of chitosan and carboxymethylchitosan on water with very high turbidity(above 300 NTU),contrasting the physicochemical results with those obtained for aluminum *** was produced by the Williamson’s ethers synthesis and characterized by potentiometric titration,FTIR and 1 *** coagulant tests were performed using synthetic water in a Jar-test equipment,through the induction of high and low velocity gradients,followed by *** results showed turbidity and color removal efficiencies above 99%for the biocoagulants,by applying dosages much lower than those used for aluminum sulphate;the volume of sedimentable solids obtained at the end of the water treatment process was much lower when chitosan and carboxymethylchitosan were used as coagulants(reduction of 25%when compared to aluminum sulphate).In summary,carboxymethylchitosan is a non-toxic,renewable,biodegradable material with high efficiency as a coagulant for waters with very high turbidity,showing promise for in natura applications.

关键词： Chitosan carboxymethylchitosan biocoagulants colloids and interfaces

Concepts perception of strategy and strategic management： University case study

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Chinese Business Review 2009年第7期8卷 48-64页

作者： Mainardes Emerson Ferreira Joao andrade Silveli Department of Management and Economics University of Beira Interior Covilha 6200-209 Portugal

Aiming to reveal the university students＇ understanding in management as for the strategy and strategic management phenomena, this study accomplishes a phenomenographic research to assess the future managers＇ market perception. It was chosen university students in Management of a Portuguese University. We conclude that the strategy definitions obtained are an assembly of the diverse existing concepts. Concerning to strategic management it was perceived an approach with one of the main existing concepts. The findings raise interesting issues with respect to the difficulties felt by new managers in translating their theoretical definitions in real examples in the organizations.

关键词： strategy strategic management phenomenographic concepts perception