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Atmospheric-pressure dielectric barrier discharge generation by a full-bridge flying capacitor multilevel inverter

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Plasma Science and Technology 2017年第7期19卷 40-49页

作者： Rosendo PE?A-EGUILUZ José A LóPEZ-FERnández Antonio mERCADO-CABRERA Bethsabet JARAmILLO-SIERRA Régulo LóPEZ-CALLEJAS benjamín rodríguez-méndez Raúl VALEnCIA-ALVARADO Allan A FLORES-FUEnTES Arturo E mU?OZ-CASTRO Plasma Physics Laboratory Instituto Nacional de Investigaciones Nucleares Tecnológico de Estudios Superiores de Tianguistenco Universidad Autónoma del Estado de méxico

A new configuration of a resonant full-bridge flying capacitor multicell inverter has been designed and constructed with the aim of achieving an extended output voltage frequency range with low harmonic distortion and reduced semiconductor commutation losses. This configuration was tested as a power supply for two different coaxial dielectric barrier discharge reactors, one of them employed for electric characterization and the other one for inorganic compound elimination in an aqueous solution. Two different gas mixtures, 90% Ar-10% 02 and 80% Ar-20% 02, were individually supplied during the experiments; the results showed a high- efficiency removal of meta-cresol （m-cresol） to the order of 98%, which was obtained by adding more oxygen to the plasma gas mixture.

关键词： plasma applications water pollution plasma sources power supply circuits electricdischarges

Dendritic spine degeneration:a primary mechanism in the aging process

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neural Regeneration Research 2025年第6期20卷 1696-1698页

作者： Gonzalo Flores Leonardo Aguilar-Hernández Fernado García-Dolores Humberto nicolini Andrea Judith Vázquez-Hernández Hiram Tendilla-Beltrán Instituto de Fisiología Benemérita Universidad Autónoma de Puebla(BUAP)PueblaMexico Instituto de Ciencias Forenses(InCIFO) Tribunal Superior de Justicia de la Ciudad de México(TSJCDMX).Mexico CityMexico Instituto nacional de medicina Genómica(InmEGEn) Mexico CityMexico

Recent reports suggest that aging is not solely a physiological process in living beings;instead, it should be considered a pathological process or disease(Amorim et al., 2022). Consequently, this process involves a wide range of factors, spanning from genetic to environmental factors, and even includes the gut microbiome(Gm)(mayer et al., 2022). All these processes coincide at some point in the inflammatory process, oxidative stress, and apoptosis, at different degrees in various organs and systems that constitute a living organism(mayer et al., 2022;AguilarHernández et al., 2023).

关键词： aging process stress

Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

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neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-merz Jorge Hernández-Campano Sergei A.Kirov Jesús m.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of neuroscience and Regenerative medicine&Department of neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by n-methyl-D-aspartate *** n-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system n transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through n-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling n-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

Data-driven drug repositioning using olfactory omics profiles:challenges and perspectives in neurodegeneration

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neural Regeneration Research 2025年第7期20卷 1997-1998页

作者： Paz Cartas-Cejudo Adriana Cortés mercedes Lachén-montes Elena Anaya-Cubero Joaquín Fernández-Irigoyen Enrique Santamaría Clinical neuroproteomics Unit Proteomics PlatformNavarrabiomedHospitalario Universitario de Navarra(HUN)Universidad Pública de Navarra(UPNA)IdiSNANavarra Institute for Health ResearchPamplonaSpain

Data-driven drug repositioning using olfactory omics profiles-challenges and perspectives in neurodegeneration:neurodegenerative diseases are characterized by progressive degeneration and loss of neuronal function in the central nervous *** diseases are often characterized as proteinopathies,which are disorders primarily driven by the aggregation or misfolding of specific amyloid proteins within cells,leading to their dysfunction and eventual *** the gain-of-function hypothesis related to the aggregation of these proteins,recently,an alternative hypothesis regarding the loss-of-function of the soluble monomeric proteins during the process of aggregation into amyloids is gaining *** last event is called proteinopenia and refers to conditions characterized by a deficiency or decrease in the levels of specific soluble proteins in the body(Ezzat et al.,2023).It has been demonstrated that levels of soluble proteins involved in neurodegenerative diseases are decreased.

关键词： diseases drug amyloid

The movement dynamics of autotomized lizards and their tails reveal functional costs of caudal autotomy

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Integrative Zoology 2020年第6期15卷 511-521页

作者： Irene FERnÁndez-rodrÍguez Florentino BRAÑA Department of Organisms and Systems Biology(Zoology) University of OviedoOviedoSpain Research Unit of Biodiversity(UmIB UO/CSIC/PA)University of OviedoMieresSpain

Autotomy has evolved independently several times in different animal *** frequently involves immediate functional costs,so regeneration evolved in many instances to restore the functionality of that body *** autotomy is a widespread antipredator strategy in lizards,although it may affect energy storage,locomotion dynamics,or survival in future encounters with ***,we assessed the effect of tail loss on the locomotor performance of wall lizards(Podarcis muralis),as well as the recovery of locomotor functionality of lizards with regenerated tails,and the movement dynamics of shed tails that were either intact or having regenerated *** loss had no effect on locomotion over unhindered spaces,possibly due to compensation between a negative effect on the stride of front limbs,and a positive effect of losing mass and friction *** found a clear negative impact of tail loss on locomotion in spaces with interspersed obstacles,in which tailed lizards jumped larger distances when leaving the ***,lizards that used the tail to push off the ground were able to approach the obstacles from further,so that the tail seemed to be useful when used during *** fully restores lizard’s locomotor capacities,but tail antipredator value,as indicated by the intensity of post-autotomic movements,is only partially *** these results,we propose that,together with the recovery of post-autotomy antipredator capacities,the restoration of the organismal locomotor performance may have been an important,yet frequently neglected factor in the evolution of lizard’s regeneration ability.

关键词： autotomy locomotor performance regeneration tail wall lizard

neurocircuit regeneration by extracellular matrix reprogramming

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neural Regeneration Research 2025年第8期20卷 2300-2301页

作者： Shengzhang Su Ian n.Levasseur Kimberly m.Alonge Department of medicinal Chemistry University of WashingtonSeattleWAUSA Department of Chemistry University of WashingtonSeattleWAUSA Department of medicine University of Washington Medicine Diabetes InstituteSeattleWAUSA

The brain's extracellular matrix(ECm),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECm regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(miyata et al.,2012),cation buffering(moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECm indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.

关键词： matrix programming

maschke Type Theorems for Weak Hopf Quasigroups

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Algebra Colloquium 2020年第2期27卷 213-230页

作者： J.n.Alonso Alvarez J.m.Fernández Vilaboa R.González rodríguez Departamento de matematicas Vniversidade de Vigo Campus Universitario Lagoas-MarcosendeE-36280 VigoSpain Departamento de matematicas Universidade de Santiago de Compostela E-15771 Santiago de CompostelaSpain Departamento de matematica Aplicada II Universidade de Vigo Campus Universitario Lagoas-MarcosendeE-36310 VigoSpain

In this paper we give necessary and sufficient conditions for a comodule magma over a weak Hopf quasigroup to have a total integral,thus extending the theories developed in the Hopf algebra,weak Hopf algebra and non-associative Hopf algebra *** this result we also deduce a version of maschke’s theorems for right(H,B)-Hopf triples associated to a weak Hopf quasigroup H and a right H-comodule magma B.

关键词： (weak)Hopf algebra (weak)Hopf quasigroup integral maschke theorem

Strong Connections and Invertible Weak Entwining Structures

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Acta mathematica Sinica,English Series 2012年第7期28卷 1443-1460页

作者： J. n. ALOnSO LVAREZ J. m. FERn ndez VILABOA GOnZ LEZ rodr íguez Departamento de matemáticas Universidad de VigoCampus Universitario Lagoas-Marcosende Departamento de lxebra Universidad de Santiago de Compostela Departamento de matemática Aplicada Ⅱ Universidad de VigoCampus Universitario Lagoas-Marcosende

In this paper we obtain a criterion under which the bijectivity of the canonical morphism of a weak Galois extension associated to a weak invertible entwining structure is equivalent to the existence of a strong connection form. Also we obtain an explicit formula for a strong connection under equivariant projective conditions or under coseparability conditions.

关键词： monoidal category invertible weak entwining structure strong connection weak Galois extension

Role of climatic variability in shaping intraspecific variation of thermal tolerance in mediterranean water beetles

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Insect Science 2024年第1期31卷 285-298页

作者： Susana Pallarés David Garoffolo Belén rodríguez David Sánchez-Fernández Department of Zoology University of SevilleSevilleSpain Faculty of Biology Department of Ecology and HydrologyUniversity of MurciaCampus EspinardoMurciaSpain

The climatic variability hypothesis(CVH)predicts that organisms in more thermally variable environments have wider thermal breadths and higher thermal plasticity than those from more stable ***,due to evolutionary trade-offs,taxa with greater absolute thermal limits may have little plasticity of such limits(trade-off hypothesis).The CVH assumes that climatic variability is the ultimate driver of thermal tolerance variation across latitudinal and altitudinal gradients,but average temperature also varies along such *** explored intraspecific variation of thermal tolerance in three typical mediterranean saline water beetles(families Hydrophilidae and Dytiscidae).For each species,we compared two populations where the species coexist,with similar annual mean temperature but contrasting thermal variability(continental *** population).We estimated thermal limits of adults from each population,previously acclimated at 17,20,or 25℃.We found species-specific patterns but overall,our results agree with the CVH regarding thermal ranges,which were wider in the continental(more variable)*** the two hydrophilid species,this came at the cost of losing plasticity of the upper thermal limit in this population,supporting the trade-off hypothesis,but not in the dytiscid *** results support the role of local adaptation to thermal variability and trade-offs between basal tolerance and physiological plasticity in shaping thermal tolerance in aquatic ectotherms,but also suggest that intraspecific variation of thermal tolerance does not fit a general pattern among aquatic *** such intraspecific variation could lead to inaccurate predictions of the vulnerability of aquatic insects to global warming.

关键词： acclimation capacity aquatic insects climate change heat coma temperature supercooling point thermal plasticity