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Ultrasound sensing with optical microcavities

light(Science & Applications) 2024年第8期13卷 1487-1511页

作者： Xuening Cao Hao Yang Zu-Lei Wu bei-bei li beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Optical and Electronic Information Huazhong University of Science and TechnologyWuhan 430074China Songshan Lake Materials Laboratory Dongguan 523808 GuangdongChina

Ultrasound sensors play an important role in biomedical imaging,industrial nondestructive inspection,*** ultrasound sensors that use piezoelectric transducers face limitations in sensitivity and spatial resolution when miniaturized,with typical sizes at the millimeter to centimeter *** overcome these challenges,optical ultrasound sensors have emerged as a promising alternative,offering both high sensitivity and spatial *** particular,ultrasound sensors utilizing high-quality factor(Q)optical microcavities have achieved unprecedented performance in terms of sensitivity and bandwidth,while also enabling mass production on silicon *** this review,we focus on recent advances in ultrasound sensing applications using three types of optical microcavities:Fabry-Perot cavities,π-phase-shifted Bragg gratings,and whispering gallery mode *** provide an overview of the ultrasound sensing mechanisms employed by these microcavities and discuss the key parameters for optimizing ultrasound ***,we survey recent advances in ultrasound sensing using these microcavity-based approaches,highlighting their applications in diverse detection scenarios,such as photoacoustic imaging,ranging,and particle *** goal of this review is to provide a comprehensive understanding of the latest advances in ultrasound sensing with optical microcavities and their potential for future development in high-performance ultrasound imaging and sensing technologies.

关键词： optical millimeter offering

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Postoperative body weight change and its influencing factors in patients with gastric cancer

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 2242-2254页

作者： Yan li li-Hua Huang Hui-Di Zhu Ping He bei-bei li li-Jing Wen Department of Gastrointestinal Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina Department of Nursing The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003Zhejiang ProvinceChina

BACKGROUND The high incidence and mortality of gastric cancer(GC)pose a significant threat to human life and health,and it has become an important public health challenge in *** weight loss is a common complication after surgical treatment in patients with GC and is associated with poor prognosis and GC ***,current attention to postoperative weight change in GC patients remains insufficient,and the descriptions of postoperative weight change and its influencing factors are also *** To investigate body weight changes in patients with GC within 6 mo after gastrectomy and identify factors that influence dynamic body weight *** We conducted a prospective longitudinal study of 121 patients with GC and collected data before(T0)and 1(T1),3(T2),and 6(T3)mo after gastrectomy using a general data questionnaire,psychological distress thermometer,and body weight *** general estimation equation(GEE)was used to analyze the dynamic trends of body weight changes and factors that influence body weight changes in patients with GC within 6 mo of *** The median weight loss at T1,T2,and T3 was 7.29%(2.84%,9.40%),11.11%(7.64%,14.91%),and 14.75%(8.80%,19.84%),*** GEE results showed that preoperative body mass index(BMI),significant psychological distress,religious beliefs,and sex were risk factors for weight loss in patients with GC within 6 mo after gastrectomy(Plikely to have weight loss(β=14.685,Plikely to lose weight than those without(β=2.490,Pligious patients were less likely to lose weight 6 mo after gastrectomy than those without religious beliefs(β=-6.844,P=0.001).Compared to female patients,male patients were more likely to experience weight loss 6 mo after gastrectomy(β=4.262,P=0.038).CONCLUSION Male patients wi

关键词： Gastric cancer Gastrectomy Weight loss Influencing factors Body mass index

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Optically sizing single atmospheric particulates with a 10-nm resolution using a strong evanescent field

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light(Science & Applications) 2018年第1期7卷 1087-1093页

作者： Xiao-Chong Yu Yanyan Zhi Shui-Jing Tang bei-bei li Qihuang Gong Cheng-Wei Qiu Yun-Feng Xiao State Key Laboratory for Mesoscopic Physics and School of Physics Peking UniversityBeijing 100871China Collaborative Innovation Center of Quantum Matter Beijing 100871China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China Department of Electrical and Computer Engineering National University of SingaporeSingapore 117583Singapore NUS Suzhou Research Institute(NUSRI) Suzhou 215123China SZU-NUS Collaborative Innovation Center for Optoelectronic Science&Technology Shenzhen UniversityShenzhen 518060China

Although an accurate evaluation of the distribution of ultrafine particulate matter in air is of utmost significance to public health,the usually used PM2.5 index fails to provide size distribution *** we demonstrate a low-profile and cavity-free size spectrometer for probing fine and ultrafine particulate matter by using the enhanced particle-perturbed scattering in strong optical evanescent fields of a nanofiber *** unprecedented size resolution reaches 10 nm for detecting single 100-nm-diameter nanoparticles by employing uniform nanofibers and controlling the polarizations of the probe *** size spectrometry was tested and used to retrieve the size distribution of particulate matter in the air of beijing,yielding mass concentrations of nanoparticles,as a secondary exercise,consistent with the officially released *** nanofiber-array probe shows potential for the full monitoring of air pollution and for studying early-stage haze evolution and can be further extended to explore nanoparticle interactions.

关键词： air pollution optical nanofiber single particulates size spectrometer

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Picotesla-sensitivity microcavity optomechanical magnetometry

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light(Science & Applications) 2024年第11期13卷 2835-2846页

作者： Zhi-Gang Hu Yi-Meng Gao Jian-Fei liu Hao Yang Min Wang Yuechen Lei Xin Zhou Jincheng li Xuening Cao Jinjing liang Chao-Qun Hu Zhilin li Yong-Chang Lau Jian-Wang Cai bei-bei li beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China School of Physics Beihang UniversityBeijing 100191China Songshan Lake Materials Laboratory Dongguan 523808 GuangdongChina

Cavity optomechanical systems have enabled precision sensing of magnetic fields,by leveraging the optical resonance-enhanced readout and mechanical resonance-enhanced *** studies have successfully achieved mass-produced and reproducible microcavity optomechanical magnetometry(MCOM)by incorporating Terfenol-D thin films into high-quality(Q)factor whispering gallery mode(WGM)***,the sensitivity was limited to 585 pT Hz^(−1/2),over 20 times inferior to those using Terfenol-D *** this work,we propose and demonstrate a high-sensitivity and mass-produced MCOM approach by sputtering a FeGaB thin film onto a high-Q SiO2 WGM *** studies are conducted to explore the magnetic actuation constant and noise-limited sensitivity by varying the parameters of the FeGaB film and SiO2 *** magnetometers with different radii are fabricated and *** utilizing a microdisk with a radius of 355μm and a thickness of 1μm,along with a FeGaB film with a radius of 330μm and a thickness of 1.3μm,we have achieved a remarkable peak sensitivity of 1.68 pT Hz^(−1/2)at 9.52 *** represents a significant improvement of over two orders of magnitude compared with previous studies employing sputtered Terfenol-D ***,the magnetometer operates without a bias magnetic field,thanks to the remarkable soft magnetic properties of the FeGaB ***,as a proof of concept,we have demonstrated the real-time measurement of a pulsed magnetic field simulating the corona current in a high-voltage transmission line using our developed *** high-sensitivity magnetometers hold great potential for various applications,such as magnetic induction tomography and corona current monitoring.

关键词： particles. magnetometer film

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Free spectral range magnetic tuning of an integrated microcavity

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Fundamental Research 2023年第3期3卷 351-355页

作者： Yuechen Lei Zhi-Gang Hu Min Wang Yi-Meng Gao Zhanchun Zuo Xiulai Xu bei-bei li beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100094China Songshan Lake Materials Laboratory DongguanGuangdong 523808China State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China

Tunable whispering-gallery-mode(WGM)microcavities are promising devices for reconfigurable photonic applications such as widely tunable integrated lasers and reconfigurable optical filters for optical communication and information *** up these devices demands the ability to tune the optical resonances in an integrated manner over a full free spectral range(FSR).Here we propose a high-speed full FSR magnetic tuning scheme of an integrated silicon nitride(Si_(3)N_(4))double-disk *** coating a magnetostrictive film on the spokes and the central pad of the Si_(3)N_(4) cavity,magnetic tuning can be realized using a microcoil integrated on the same *** FSR tuning can be achieved by combining magnetostrictive strain with strong optomechanical interactions provided by the double-disk *** calculate the required magnetic flux density to tune an FSR(B_(FSR))as a function of several key geometric parameters,including the air gap,radius,width of the spokes and ring of the double-disk cavities,as well as the thickness of the magnetostrictive *** proposed structure enables a full FSR tuning with a required magnetic flux density of milli-Tesla(mT)*** also study the dynamic response of the integrated device with an alternating current(AC)magnetic field driving,and find that the tuning speed can reach hundreds of kHz in the air.

关键词： Optical microcavities Tunable microcavities Optomechanics Magnetic tuning Integrated photonic devices

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Alternaria toxin-induced resistance in rose plants against rose aphid(Macrosiphum rosivorum): effect of tenuazonic acid

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2015年第4期16卷 264-274页

作者： Fa-zhong YANG Bin YANG bei-bei li Chun XIAO School of Plant Protection Yunnan Agricultural University Key Laboratory of Forest Disaster Warning and Control of Yunnan Province Southwest Forestry University

Many different types of toxins are produced by the fungus, Alternaria alternata （Fr.） Keissler. little is known, however, regarding the influence of these toxins on insects. In this study, we investigated the toxin-induced inhibitory effects of the toxin produced by A. alternata on the rose aphid, Macrosiphum rosivorum, when the toxin was applied to leaves of the rose, Rosa chinensis. The results demonstrated that the purified crude toxin was non-harmful to rose plants and rose aphids, but had an intensive inhibitory effect on the multiplication of aphids. The inhibitory index against rose aphids reached 87.99% when rose plants were sprayed with the toxin solution at a low concentration. Further results from bioassays with aphids and high performance liquid chromatography （HPLC） analyses demon- strated that tenuazonic acid （TEA） was one of the most important resistance-related active components in the crude toxin. The content of TeA was 0.1199% in the crude toxin under the HPLC method. Similar to the crude toxin, the inhibitory index of pure TeA reached 83.60% 15 d after the rose plants were sprayed with pure TeA solution at the lower concentration of 0.060 IJg/ml, while the contents of residual TeA on the surface and in the inner portion of the rose plants were only 0.04 and 0.00 ng/g fresh weight of TeA-treated rose twigs, respectively, 7 d after the treatment. Our results show that TeA, an active component in the A. alternata toxin, can induce the indirect plant-mediated re- sponses in rose plants to intensively enhance the plant＇s resistances against rose aphids, and the results are very helpful to understand the plant-mediated interaction between fungi and insects on their shared host plants.

关键词： Toxin Induced resistance Fungus-plant-insect system Plant-mediated interaction Tenuazonic acid Alternaria altemata Macrosiphum rosivorum

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Anisotropies of the g-factor tensor and diamagnetic coefficient in crystal-phase quantum dots in InP nanowires

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Nano Research 2019年第11期12卷 2842-2848页

作者： Shiyao Wu Kai Peng Sergio Battiato Valentina Zannier Andrea Bertoni Guido Goldoni Xin Xie Jingnan Yang Shan Xiao Chenjiang Qian Feilong Song Sibai Sun Jianchen Dang Yang Yu Fabio Beltram Lucia Sorba Ang li bei-bei li Francesco Rossella Xiulai Xu beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing100190China CAS Center for Excellence in Topological Quantum Computation and School of Physical Sciences University of Chinese Academy of SciencesBeijing100049China Laboratorio NEST Scuola Normale Superiore and Istituto Nanoscienze-CNRPiazza S.Silvestro 12I-56127PisaItaly S3 Istituto Nanoscienze-CNRVia Campi 213/aModena41125Italy Dipartimento di Scienze Fisiche Informatiche e MatematicheUniversitàdegli Studi di Modena e Reggio EmiliaVia Campi 213/aModena41125Italy beijing Key Lab of Microstructure and Property of Advanced Materials Beijing University of TechnologyPingleyuan No.100Beijing100024China Songshan Lake Materials Laboratory Dongguan523808China

Crystal-phase low-dimensional structures offer great potential for the implementation of photonic devices of interest for quantum information *** this context,unveiling the fundamental parameters of the crystal phase structure is of much relevance for several ***,we report on the anisotropy of the g-factor tensor and diamagnetic coefficient in wurtzite/zincblende(WZ/ZB)crystal-phase quantum dots(QDs)realized in single InP *** WZ and ZB alternating axial sections in the NWs are identified by high-angle annular dark-field scanning transmission electron *** electron(hole)g-factor tensor and the exciton diamagnetic coefficients in WZ/ZB crystal-phase QDs are determined through micro-photoluminescence measurements at low temperature(4.2 K)with different magnetic field configurations,and rationalized by invoking the spin-correlated orbital current *** work provides key parameters for band gap engineering and spin states control in crystal-phase low-dimensional structures in nanowires.

关键词： g-factor tensor diamagnetic coefficient crystal-phase quantum dot InP NWs

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Optical-Microwave Entanglement Paves the Way for Distributed Quantum Computation

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Chinese Physics Letters 2024年第1期41卷 21-24页

作者：胡志刚许凯张玉祥李贝贝 beijing National Laboratory for Condensed Matter Physics and Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China

Over the past few years,quantum computation based on superconducting circuits has achieved remarkable progress.A milestone occurred in 2019 when Google released Sycamore,a processor with 54 qubits,and claimed quantum supremacy by performing in just 100 s a specific computation which would take a classical supercomputer,as stated by Google’s team,10000 years to complete.[1]In 2021,a strong quantum advantage was demonstrated by Pan and his colleagues from the University of Science and Technology of China,using a quantum processor named Zuchongzhi,which has 66 functional qubits.[2]This year,the record of the number of quantum qubits has been lifted to 127 qubits.[3]Indeed,the number of qubits is limited to a few hundreds due to the finite space of dilution refrigerators,where the superconducting qubits must be placed to be isolated from thermal ***,this number is still several orders of magnitude away from the requirement of quantum error correction,which is essential for general-purpose quantum computers.[4–8].

关键词： quantum stated correction

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Coupling ideality of standing-wave supermode microresonators

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Photonics Research 2024年第8期12卷 1610-1618页

作者： MIN WANG YUECHEN LEI ZHI-GANG HU CHENGHAO LAO YUANLEI WANG XIN ZHOU JINCHENG li QI-FAN YANG bei-bei li beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics School of PhysicsPeking UniversityBeijing 100871China School of Physics Beihang UniversityBeijing 100191China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China Songshan Lake Materials Laboratory Dongguan 523808China

Standing-wave supermode microresonators that are created through the strong coupling between counter-propagating modes have emerged as versatile platforms for sensing and nonlinear *** example,these microresonators have shown potential in nanoparticle sizing and counting,as well as enhancing the single-photon optomechanical coupling rate of stimulated Brillouin ***,it has been observed that the relation between the mode linewidth and on-resonance transmission of the split supermodes differs obviously from that of the non-split *** behavior is typically quantified by the coupling ideality(I),which remains inadequately explored for the standing-wave *** this study,we theoretically and experimentally investigate the coupling ideality of standing-wave supermodes in a commonly employed configuration involving a Si O2microresonator side-coupled to a tapered *** findings demonstrate that,even with a single-mode tapered fiber,the coupling ideality of the standing-wave supermodes is limited to 0.5,due to the strong backscattering-induced energy loss into the counter-propagating direction,resulting in an additional equivalent parasitic *** achieving a coupling ideality of 0.5 presents challenges for reaching over-coupled regimes,it offers a convenient approach for adjusting the total linewidth of the modes while maintaining critically-coupled conditions.

关键词： ideality mode wave

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Ultrabroadband and sensitive cavity optomechanical magnetometry

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Photonics Research 2020年第7期8卷 1064-1071页

作者： bei-bei li George Brawley Hamish Greenall Stefan Forstner Eoin Sheridan Halina Rubinsztein-Dunlop Warwick P.Bowen Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Mathematics and Physics The University of QueenslandSt LuciaQLD 4072Australia

Magnetostrictive optomechanical cavities provide a new optical readout approach to room-temperature *** we report ultrasensitive and ultrahigh bandwidth cavity optomechanical magnetometers constructed by embedding a grain of the magnetostrictive material Terfenol-D within a high quality(Q)optical microcavity on a silicon *** engineering their physical structure,we achieve a peak sensitivity of26 p T∕Hz1/2 p comparable to the best cryogenic microscale magnetometers,along with a 3 d B bandwidth as high as 11.3 *** classes of magnetic response are observed,which we postulate arise from the crystallinity of the *** allows single crystalline and polycrystalline grains to be distinguished at the level of a single *** results may enable applications such as lab-on-chip nuclear magnetic spectroscopy and magnetic navigation.

关键词： cavity magnetometer magneto

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