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Therapeutic potential of flavonoids in inflammatory bowel disease: A comprehensive review

World Journal of Gastroenterology 2017年第28期23卷 5097-5114页

作者： Ali Salaritabar behrad darvishi Farzaneh Hadjiakhoondi Azadeh Manayi Antoni Sureda Seyed Fazel Nabavi Leo R Fitzpatrick Seyed Mohammad Nabavi Anupam Bishayee Department of Integrative oncology Breast Cancer Research CenterMotamed Cancer InstituteACECR Department of Recombinant Protein Breast Cancer Research CenterMotamed Cancer InstituteACECR Medicinal Plants Research Center Faculty of PharmacyTehran University of Medical Sciences Research Group on Community Nutrition and oxidative Stress and CIBERo BN-Physiopathology of obesity and Nutrition University of Balearic IslandsPalma de Mallorca Applied Biotechnology Research Center Baqiyatallah University of Medical Sciences Department of Pharmaceutical and Biomedical Sciences California Northstate University College of Pharmacy Department of Pharmaceutical Sciences College of PharmacyLarkin University

The inflammatory process plays a central role in the development and progression of numerous pathological situations,such as inflammatory bowel disease(IBD),autoimmune and neurodegenerative diseases,metabolic syndrome,and cardiovascular disorders. IBDs involve inflammation of the gastrointestinal area and mainly comprise Crohn's disease(CD) and ulcerative colitis(UC). Both pathological situations usually involve recurring or bloody diarrhea,pain,fatigue and weight loss. There is at present no pharmacological cure for CD or UC. However,surgery may be curative for UC patients. The prescribed treatment aims to ameliorate the symptoms and prevent and/or delay new painful episodes. Flavonoid compounds are a large family of hydroxylated polyphenolic molecules abundant in plants,including vegetables and fruits which are the major dietary sources of these compounds for humans,together with wine and tea. Flavonoids are becoming very popular because they have many health-promoting and disease-preventive effects. Most interest has been directed towards the antioxidant activity of flavonoids,evidencing a remarkable free-radical scavenging capacity. However,accumulating evidence suggests that flavonoids have many other biological properties,including anti-inflammatory,antiviral,anticancer,and neuroprotective activities through different mechanisms of action. The present review analyzes the available data about the different types of flavonoids and their potential effectiveness as adjuvant therapy of IBDs.

关键词： Antioxidant Inflammation Gastrointestinal tract Flavonoids Polyphenols

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A novel approach to study generalized coupled cubic Schrödinger-Korteweg-de Vries equations

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Journal of Ocean Engineering and Science 2024年第1期9卷 13-24页

作者： Lanre Akinyemi P.Veeresha M.T.darvishi Hadi Rezazadeh Mehmet Senol Udoh Akpan Department of Mathematics Lafayette CollegeEastonPAUSA Department of Mathematics Christ Deemed to be UniversityBengaluru 560029India Department of Mathematics Razi UniversityKermanshah 67149Iran Faculty of Engineering Technology Amol University of Special Modern TechnologiesAmolIran Department of Mathematics Nev¸s ehir HacıBekta¸s Veli UniversityNev¸s ehirTurkey Drexel University Department of MathematicsPhiladelphiaPAUSA

The Kortewegde Vries(KdV)equation represents the propagation of long waves in dispersive media,whereas the cubic nonlinear Schrödinger(CNLS)equation depicts the dynamics of narrow-bandwidth wave packets consisting of short dispersive waves.A model that couples these two equations seems in-triguing for simulating the interaction of long and short waves,which is important in many domains of applied sciences and engineering,and such a system has been investigated in recent *** work uses a modified Sardar sub-equation procedure to secure the soliton-type solutions of the generalized cubic nonlinear Schrödinger-Korteweg-de Vries system of *** various selections of arbitrary parameters in these solutions,the dynamic properties of some acquired solutions are represented graph-ically and *** particular,the dynamics of the bright solitons,dark solitons,mixed bright-dark solitons,W-shaped solitons,M-shaped solitons,periodic waves,and other soliton-type *** re-sults demonstrated that the proposed technique is highly efficient and effective for the aforementioned problems,as well as other nonlinear problems that may arise in the fields of mathematical physics and engineering.

关键词： CNLS equation Modiﬁed Sardar sub-equation method KdV equation Solitons Long and short waves

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A Modification of Extended Homoclinic Test Approach to Solve the(3+1)-Dimensional Potential-YTSF Equation

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Chinese Physics Letters 2011年第4期28卷 4-7页

作者： M.T.darvishi Mohammad Najafi Department of Mathematics Razi UniversityKermanshah 67149Iran

By means of the extended homoclinic test approach(EHTA)one can solve some nonlinear partial differential equations(NLPDEs)in their bilinear *** an NLPDE has no bilinear closed form we can not use this *** modify the idea of EHTA to obtain some analytic solutions for the(3+1)-dimensional potential-Yu-Toda-Sasa-Fukuyama(YTSF)equation by obtaining a bilinear closed form for *** comparison of this method and other analytic methods,like HAM,HTA and three-wave methods,we can see that the new idea is very easy and straightforward.

关键词： method bilinear analytic

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A sensitivity analysis and multi-objective optimization to enhance ethylene production by oxidative dehydrogenation of ethane in a membrane-assisted reactor

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Chinese Journal of Chemical Engineering 2018年第9期26卷 1879-1895页

作者： Ali darvishi Ali Bakhtyari Mohammad Reza Rahimpour Department of Chemical Engineering Shiraz University

Owing to the importance of process intensification in the natural gas associated processes, the present contribution aims to investigate the production of an important natural gas downstream product in an improved ***, a membrane-assisted reactor for the oxidative dehydrogenation of ethane is presented. The presented system includes a membrane for axial oxygen dosing into the reaction side. Such a strategy would lead to optimum oxygen distribution along the reactor length and prevention of hot spot formation as well. A feasibility study is conducted by developing a validated mathematical model composed of mass and energy balance equations. The effects of various operating variables are investigated by a rigorous sensitivity ***, by applying the genetic algorithm, a multi-objective optimization procedure is implemented to obtain the optimum operating condition. Considerable increase in the ethane conversion and ethylene yield are the advancements of membrane-assisted oxidative dehydrogenation reactor working under the optimum *** than 30% increase in the ethane conversion is obtained. Furthermore, the ethylene yield is enhanced up to 0.45.

关键词： Olefin ODH process Genetic algorithm Fixed-bed Mathematical modeling Chemical reactors

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Preparation of hydrophobic flat sheet membranes from PVDF-HFP copolymer for enhancing the oxygen permeance in nitrogen/oxygen gas mixture

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Chinese Journal of Chemical Engineering 2020年第6期28卷 1566-1581页

作者： Bahador Akbari Asghar Lashanizadegan Parviz darvishi Abdolrasoul Pouranfard Department of Chemical Engineering School of EngineeringYasouj UniversityYasoujIran

In this study, poly(vinilydene fluoride-co-hexafluoropropylene)(PVDF-HFP) was used for preparation of hydrophobic membranes using non-solvent induced phase inversion(NIPS) technique. PVDF-HFP copolymer with concentrations of 10 wt% and 12 wt% was prepared to investigate the effect of polymer concentration on pore structure,morphology, hydrophobicity and performance of prepared membranes. Besides, the use of two coagulation baths with the effects of parameters such as coagulant time, polymer type and concentration, and the amount of nonsolvent were studied. The performance of prepared membranes was evaluated based on the permeability and selectivity of oxygen and nitrogen from a gas mixture of nitrogen/oxygen under operating conditions of feed flow rate(1–5 L·min-1), inlet pressure to membrane module(0.1–0.5 MPa) and temperatures between 25 and 45 °C. The results showed that the use of two coagulation baths with different compositions of distillated water and isopropanol,coagulant time, polymer type and concentration, and the amount of non-solvent additive have the most effect on pore structure, morphology, thickness, roughness and crystallinity of fabricated membranes. Porosity ranges for the three fabricated membranes were determined, where the maximum porosity was 73.889% and the minimum value was 56.837%. Also, the maximum and minimum average thicknesses of membrane were 320.85 μm and115 μm. Besides, the values of 4.7504 × 10-7 mol· m-2· s-1· Pa-1, 0.525 and 902.126 nm were achieved for maximum oxygen permeance, O2/N2 selectivity and roughness, respectively.

关键词： Oxygen-enriched air Hydrophobic flat sheet membrane PVDF-HFP copolymer Enhancing oxygen permeance Pore structure

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New Exact Solutions of a Relativistic Toda Lattice System

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Chinese Physics Letters 2012年第9期29卷 53-56页

作者： M.T.darvishi F.Khani Department of Mathematics Razi UniversityKermanshah 67149Iran

We study the application of the exp-function method to solve a relativistic Toda lattice *** reduce the original equation into a convenient form,a suitable transformation is used so that the so-called exp-function method can be *** using the homogeneous balance principle and some further analysis,we succeed in calculating some exact analytic solutions.

关键词： convenient exact calculating

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A simple and efficient procedure for the synthesis of optically active s-triazolothiadiazole derivatives

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Chinese Chemical Letters 2012年第12期23卷 1335-1338页

作者： Sattar Ebrahimi Masoomeh Sayadi Ghasem darvishi Department of Chemistry Malayer Branch Islamic Azad University Young Researchers Club Malayer BranchIslamic Azad University Department of Chemistry Markazi Province Education

A series of novel s-triazolothiadiazoles 3a-h were prepared by condensation reaction of substituted amino triazoles 1a-b with N-phethaloyl-L-amino acids 2a-d in the presence of the phosphoroxy chloride （POC13） as an anhydrous reagent. The structure of all synthesized compounds was confirmed by IR, 1H NMR, arid 13C NMR spectroscopy.

关键词： s-Tfiazolothiadiazole L-Amino acid 1,2,4-Triazole-3-thiol Optical activity Phosphorus oxychloride

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Modeling-based optimization of a fixed-bed industrial reactor for oxidative dehydrogenation of propane

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Chinese Journal of Chemical Engineering 2016年第5期24卷 612-622页

作者： Ali darvishi Razieh Davand Farhad Khorasheh Moslem Fattahi Department of Chemical and Petroleum Engineering Shiraz UniversityShirazIran Department of Chemical and Petroleum Engineering Sharif University of TechnologyAzadi AvenueTehranIran Department of Chemical Engineering Abadan Faculty of Petroleum Engineering Petroleum University of TechnologyAbadanIran

An industrial scale propylene production via oxidative dehydrogenation of propane （ODHP） in multi-tubular re- actors was modeled. Multi-tubular fixed-bed reactor used for ODHP process, employing 10000 of small diameter tubes immersed in a shell through a proper coolant flows. Herein, a theory-based pseudo-homogeneous model to describe the operation of a fixed bed reactor for the ODHP to correspondence olefln over V2O5/γ-Al203 catalyst was presented. Steady state one dimensional model has been developed to identify the operation parameters and to describe the propane and oxygen conversions, gas process and coolant temperatures, as well as other pa- rameters affecting the reactor performance such as pressure. Furthermore, the applied model showed that a double-bed multitubular reactor with intermediate air injection scheme was superior to a single-bed design due to the increasing of propylene selectivity while operating under lower oxygen partial pressures resulting in propane conversion of about 37.3%. The optimized length of the reactor needed to reach 100% conversion of the oxygen was theoretically determined. For the single-bed reactor the optimized length of 11.96 m including 0.5 m of inert section at the entrance region and for the double-bed reactor design the optimized lengths of 5.72 m for the first and 7.32 m for the second reactor were calculated. Ultimately, the use of a distributed oxygen feed with limited number of injection points indicated a significant improvement on the reactor performance in terms of propane conversion and propylene selectivity. Besides, this concept could overcome the reactor run- away temperature problem and enabled operations at the wider range of conditions to obtain enhanced propyl- ene production in an industrial scale reactor.

关键词： Fixed-bed reactor Mathematical modeling Oxidative dehydrogenation of propane Propylene V2O5/γ-Al203 catalyst Optimization

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Herpes zoster in breast cancer：a case report

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The Journal of Biomedical Research 2017年第4期31卷 370-372页

作者： Mohammad darvishi Narges Vasei Infectious Diseases and Tropical Medicine Research Center (IDTMRC) AJA University of Medical Sciences TehranIran Department of Surgery AJA University of Medical Sciences Tehran Iran

There is little information on herpes zoster infection in breast cancer patients as a complication during adjuvant *** report a case of herpes zoster in a 65-year-old woman presented with low grade fever and vital signs together with skin symptoms such as severe edema,irritation and itching in the left breast where there was wound *** test revealed varicella zoster *** the best of our knowledge,the histologic features coupled with PCR led to a diagnosis of herpes zoster.

关键词： herpes zoster breast diagnosis PCR treatment

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New Exact Solutions to the (2+1)-Dimensional Ablowitz-Kaup-Newell-Segur Equation: Modification of the Extended Homoclinic Test Approach

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Chinese Physics Letters 2012年第4期29卷 3-6页

作者： Mohammad Najafi Maliheh Najafi M.T.darvishi Department of Physiology Faculty of MedicineKermanshah University of Medical SciencesKermanshahIran Department of Mathematics Razi UniversityKermanshah 67149Iran

By means of modification of the extended homoclinic test approach (mEHTA),we obtain some new exact soliton solutions for the (2+1)-dimensional Ablowitz-Kaup-Newell-Segur (AKNS) equation by obtaining a bilinear closed ... 详细信息

关键词： soliton bilinear exact

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