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carbon Dioxide/Methane Separation by Adsorption on Sepiolite

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Journal of Natural Gas chemistry 2007年第3期16卷 235-243页

作者： José A.Delgado María A.Uguina José L.Sotelo beatriz Ruíz Marcio Rosário Department of chemical Engineering Universidad Complutense de Madrid28040Madrid.Spain

In this work, the use of sepiolite for the removal of carbon dioxide from a carbon dioxide/methane mixture by a pressure swing adsorption （PSA） process has been researched. Adsorption equilibrium and kinetics have been measured in a fixed-bed, and the adsorption equilibrium parameters of carbon dioxide and methane on sepiolite have been obtained. A model based on the LDF approximation has been employed to simulate the fixed-bed kinetics, using the Langmuir equation to describe the adsorption equilibrium isotherm. The functioning of a PSA cycle for separating carbon dioxide/methane mixtures using sepiolite as adsorbent has also been studied. The experimental results were compared with the ones predicted by the model adapted to a PSA system. Methane with purity higher than 97% can be obtained from feeds containing carbon dioxide with concentrations ranging from 34% to 56% with the proposed PSA cycle. These results suggest that sepiolite is an adsorbent with good properties for its employment in a PSA cycle for carbon dioxide removal from landfill gases.

关键词： carbon dioxide methane sepiolite adsorption fixed-bed pressure swing adsorption

Usher syndrome:Genetic diagnosis and current therapeutic approaches

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World Journal of Otorhinolaryngology 2024年第1期11卷 1-17页

作者： beatriz Rocha cuzzuol Jonathan Santos Apolonio Ronaldo Teixeira da Silva Júnior Lorena Sousa de carvalho Luana Kauany de SáSantos Luciano Hasimoto Malheiro Marcel Silva Luz Mariana Santos calmon Henrique de Lima crivellaro Fabian Fellipe Bueno Lemos Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil

Usher Syndrome(USH)is the most common deaf-blind syndrome,affecting approximately 1 in 6000 people in the deaf *** genetic condition is characterized by a combination of hearing loss(HL),retinitis pigmentosa,and,in some cases,vestibular *** the subtypes of USH,USH type 1 is considered the most severe form,presenting profound bilateral congenital deafness,vestibular areflexia,and early onset *** type 2 is the most common form,exhibiting congenital moderate to severe HL for low frequencies and severe to profound HL for high ***,type 3 is the rarest,initially manifesting mild symptoms during childhood that become more prominent in the first decades of *** dual impact of USH on both visual and auditory senses significantly impairs patients'quality of life,restricting their daily activities and interactions with *** date,9 genes have been confirmed so far for USH:MYO7A,USH1c,cDH23,PcDH15,USH1G,USH2A,ADGRV1,WHRN and *** genes are inherited in an autosomal recessive manner and encode proteins expressed in the inner ear and retina,leading to functional *** non-genetic methods can assist in patient triage and disease extension evaluation,genetic and molecular tests play a pivotal role in providing genetic counseling,enabling appropriate gene therapy,and facilitating timely cochlear implantation(cI).The cRISPR/cas9 system and viral-based gene replacement therapy have recently emerged as highly promising techniques for treating *** drug therapy,PTc-124 and Nb54 have been identified as promising drug interventions for genetic HL in ***,cI has proven to be critical in the restoration of *** review aims to summarize the genetic and molecular diagnosis of USH and highlight the importance of early diagnosis in cuzzuol BR et *** and current treatments of USH WJO https://*** 2 January 19,2024 Volume 11 Issue 1 guiding appropriate treatment strategies and i

关键词： Usher syndromes Hearing loss Retinitis pigmentosa Diagnosis Genetic therapies cochlear implantation Quality of life

Anti-inflammatory effects of Mangifera indica *** in a model of colitis

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World Journal of Gastroenterology 2010年第39期16卷 4922-4931页

作者： Lucía Márquez beatriz G Pérez-Nievas Icíar Gárate Borja García-Bueno José LM Madrigal Luis Menchén Gabino Garrido Juan c Leza Department of Pharmacology School of MedicineUniversity Complutense and Centro de Investigación en Red de Salud Mental(CIBERSAM) Pharmaceutical chemistry center and University of La Habana Health Research Institute Hospital 12 de Octubre(I+12) Gastroenterology Service Hospital General Universitario Gregorio Maraón and CIBEREHD Department of chemistry and Pharmacy University Católica del Norte

AIM:To investigate the effect of aqueous extract from Mangifera indica L.(MIE)on dextran sulfate sodium (DSS)-induced colitis in ***:MIE(150 mg/kg)was administered in two different protocols:(1)rectally,over 7 d at the same time as DSS administration;and(2)once daily over 14 d (by oral gavage,7 d before starting DSS,and rectally for 7 d during DSS administration).General observations of clinical signs were ***-inflammatory activity of MIE was assessed by myeloperoxidase(MPO)activity. colonic lipid peroxidation was determined by measuring the levels of thiobarbituric acid reactive substances (TBARS).Reduced glutathione(GSH)levels,expression of inflammatory related mediators[inducible isoforms of nitric oxide synthase(iNOS)and cyclooxygenase (cOX)-2,respectively]and cytokines[tumor necrosis factor(TNF)-αand TNF receptors 1 and 2]in colonic tissue were also ***(IL)-6 and TNF-α serum levels were also measured. RESULTS:The results demonstrated that MIE has anti-inflammatory properties by improvement of clinical signs,reduction of ulceration and reduced MPO activity when administered before *** addition,administration of MIE for 14 d resulted in an increase in GSH and reduction of TBARS levels and iNOS,cOX-2, TNF-αand TNF R-2 expression in colonic tissue,and a decrease in IL-6 and TNF-αserum levels. cONcLUSION:MIE has anti-inflammatory activity in a DSS-induced rat colitis model and preventive administration(prior to DSS)seems to be a more effective protocol.

关键词： Oxidative stress Ulcerative colitis Inflammation Polyphenols Mangifera indica Antioxidants

Are endophytes an important link between airborne spores and allergen exposure?

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Fungal Diversity 2013年第3期60卷 33-42页

作者： beatriz R.Vázquez de Aldana Gerald Bills Iñigo Zabalgogeazcoa Instituto de Recursos Naturales y Agrobiología de Salamanca(IRNASA-cSIc) Cordel de Merinas 40-5237008 SalamancaSpain Texas Therapeutics Institute The Brown Foundation Institute for Molecular MedicineUniversity of Texas Health Science Center at Houston1825 Pressler StreetHoustonTX 77030USA

Grasses represent one of the Earth’s most common plant groups,and natural and cultivated habitats dominated by grasses cover about 40%of the land *** turn,each grass species hosts multiple fungal species which can behave as *** analysis of the endophytic taxa identified in surveys conducted in 14 grass species showed that some of the most frequent taxa on each grass were also present across several host *** taxa were Alternaria,Epicoccum,cladosporium,Fusarium,and a few others.A similar analysis of airborne fungi surveyed at 41 different locations throughout the world showed that some of the most geographically widespread,and most locally frequent airborne fungi belonged to the same genera that are dominant endophytes in grasses(***,Alternaria,Fusarium,etc.).Therefore,airborne spores of genera that are ubiquitous in grasses are common worldwide and attain high atmospheric *** addition,spores of the above mentioned fungi are also important respiratory *** observation indicates that saprobic colonization and sporulation of non-systemic grass endophytes could become unrestrained when their host plant tissue ***,when appropriate environmental conditions favour sporulation on grass host surfaces,the natural cycle for airborne conidia initiates,and large numbers of these conidia disperse as inoculum for new endophytic ***,the cycle of endophytism may be an important link between climate,plant biology and public health.

关键词： Grasses Airborne spores Endophytes cladosporium Alternaria Fusarium Epicoccum

Maize forage aptitude: combining ability of inbred lines and stability of hybrids

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The crop Journal 2014年第6期2卷 407-418页

作者： Luis Máximo Bertoia Mónica beatriz Aulicino Department of Plant Production Faculty of Agrosciences National University of Lomas de Zamora Camino de Cintura km 21832 Lomas de Zamora Buenos Aires Argentina Department of Genetics Faculty of Agrosciences National University of Lomas de Zamora Camino de Cintura km 2 1832 Lomas de ZamoraBuenos Aires Argentina Santa catalina Plant Breeding Institute National University of La Plata CC 4 1836 Llavallol Buenos Aires Argentina

Breeding of forage maize should combine improvement achieved for grain with the specific needs of forage hybrids. Production stability is important when maize is used for silage if the planting area is not in the ideal agronomic environment. The objectives of the present research were:(i) to quantify environmental and genetic and their interaction effects on maize silage traits;(ii) to identify possible heterotic groups for forage aptitude and suggest the formation of potential heterotic patterns, and(iii) to identify suitable inbred line combinations for producing hybrids with forage aptitude. Forty-five hybrids derived from diallelic crosses(without reciprocals) among ten inbred lines of maize were evaluated in this study. combined ANOVA over environments showed differences between genotypes(G), environments(E), and their interactions(GEI). Heritability(H2), and genotypic and phenotypic correlations were estimated to evaluate the variation in and relationships between forage traits. Postdictive and predictive AMMI models were fitted to determine the importance of each source of variation, G, E, and GEI, and to select genotypes simultaneously on yield, quality and stability. A predominance of additive effects was found in the evaluated traits. The heterotic pattern Reid-BSSS × Argentine flint was confirmed for ear yield(EY) and harvest index(HI). High and broad genetic variation was found for stover and whole plant traits. Some inbred lines had genes with differential breeding aptitude for ear and stover. Stover and ear yield should be the main breeding objectives in maize forage breeding.

关键词： Zea mays L. Forage maize combining ability GEI interaction Stover and ear digestibility

Effects of nutrients on immunomodulation in patients with severe cOVID-19:current knowledge

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World Journal of critical care Medicine 2022年第4期11卷 201-218页

作者： Bruna Teixeira da costa Glauber Rocha Lima Araújo Ronaldo Teixeira da Silva Júnior Luana Kauany de SáSantos Vinícius Lima de Souza Gonçalves Daniel Bastos alves Lima beatriz Rocha cuzzuol Jonathan Santos Apolonio Lorena Sousa de carvalho Hanna Santos Marques camilo Santana Silva Isadora de Souza Barcelos Márcio Vasconcelos Oliveira Fabrício Freire de Melo Instituto Multidisciplinar em Saúde Universidade Federal da BahiaVitória da Conquista 45029-094BahiaBrazil campus Vitória da conquista Universidade Estadual do Sudoeste da BahiaVitória da Conquista 45083-900BahiaBrazil

Recent research has demonstrated that critically ill patients with coronavirus disease 2019(cOVID-19)show significant immune system *** to that,some nutrients that influence immunomodulation have been suggested as a form of treatment against the *** review collected the information on the impact of vitamins on the prognosis of cOVID-19,with the intention of facilitating treatment and prevention of the disease risk status in *** collected information was obtained using the PubMed electronic database by searching for articles that relate cOVID-19 and the mechanisms/effects of the nutrients:Proteins,glucose,lipids,vitamin B12,vitamin D,calcium,iron,copper,zinc,and magnesium,including prospective,retrospective,and support *** findings reveal an optimal response related mainly to omega-3,eicosapentaenoic acid,docosahexaenoic acid,calcium,and iron that might represent benefits in the treatment of critically ill ***,nutrient supplementation should be done with caution due to the limited availability of randomized controlled studies.

关键词： cOVID-19 Immunomodulation Patient care Vitamins Nutrients Micronutrients

Determination of the density of zinc powders for alkaline battery

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电池 2007年第1期37卷 36-37页

作者： beatriz Ares Tejero David Guede carnero cegasa S.A.Celaya Emparanza Galdos S.A.01013 Vitoria-GasteizSpain

The density of zinc powder for alkaline battery was determined using a *** results showed that powders made before the end of 2003 could reach relative densities above 99% of the theoretical *** the relative volume sw... 详细信息

关键词：碱性电池锌粉密度测定方法

Targeting PcSK9:a promising adjuvant strategy in cancer immunotherapy

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Signal Transduction and Targeted Therapy 2021年第4期6卷 1081-1083页

作者： catarina R.Almeida beatriz H.Ferreira lola F.Duarte iBiMED-Institute of Biomedicine Department of Medical SciencesUniversity of AveiroAveiroPortugal cIcEcO-Aveiro Institute of Materials Department of ChemistryUniversity of AveiroAveiroPortugal

Treatment with immune checkpoint inhibitors(IcIs)has drastically improved the prognosis of certain advanced-stage ***,low response rates and the development of resistance remain important *** a study recently published in Nature,Li et *** that antibody inhibitors of proprotein convertase subtilisin/kexin type 9(PcSK9),FDA-approved for hyperlipidemia treatment,have the potential to boost the anticancer efficacy of IcIs.

关键词： al. prognosis adjuvant

Immunomodulatory biomaterial-based wound dressings advance the healing of chronic wounds via regulating macrophage behavior

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Regenerative Biomaterials 2022年第1期9卷 1131-1142页

作者： Ana beatriz Sousa Artur P.Águas Mário A.Barbosa Judite N.Barbosa i3S—Instituto de Inovaçäo e Investigaçäo em Saúde Universidade do PortoRua Alfredo Allen2084200-125 PortoPortugal INEB—Instituto de Engenharia Biomédica Rua Alfredo Allen2084200-125 PortoPortugal IcBAS—Instituto de ciências Biomédicas Abel Salazar Universidade do PortoRua de Jorge Viterbo Ferreira2284050-313 PortoPortugal UMIB—Unit for Multidisciplinary Biomedical Research of IcBAS—Instituto de ciências Biomédicas de Abel Salazar Universidade do PortoRua de Jorge Viterbo Ferreira2284050-313 PortoPortugal

Successful wound healing is a process that has three overlying phases:inflammatory,proliferative and *** wounds are characterized by a perpetuated inflammation that inhibits the proliferative and remodeling phases and impairs the wound *** are key modulators of the wound healing ***,they are responsible for the wound cleaning and for the phagocytosis of pathogens and afterwards they lead to the resolution of the inflammatory response and they express growth factors important for angiogenesis and cytokines and growth factors needed for cell proliferation and deposition of extracellular *** phenotype of the macrophage changes gradually throughout the healing process from the initial M1 pro-inflammatory phenotype characteristic of the acute response to the M2 pro-regenerative phenotype that allows an accurate tissue *** chronic wounds,M1 pro-inflammatory macrophages persist and impair tissue *** such,immunomodulatory biomaterials arise as promising solutions to accelerate the wound healing *** this review,we discuss the importance of macrophages and their polarization throughout the different phases of wound healing;macrophage dysfunction in chronic wounds and the use of immunomodulatory biomaterials to overcome the critical problem of chronic wounds-the continued inflammatory phase that impairs healing.

关键词： wound healing chronic wounds macrophage immunomodulatory biomaterials