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Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina Pierzynowska bartosz Karaszewski Grzegorz Węgrzyn Department of Molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and owing to their prevalence,severity.

关键词： organs Alzheimer death

Is hydrogen peroxide generated in wine?

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Food Bioscience 2022年第1期45卷 393-396页

作者： Anna Tama Grzegorz bartosz Izabela Sadowska-bartosz Laboratory of Analytical Biochemistry Institute of Food Technology and NutritionCollege of Natural SciencesRzeszow University35-601RzeszowPoland Department of Bioenergetics Food Analysis and MicrobiologyInstitute of Food Technology and NutritionCollege of Natural SciencesRzeszow University35-601RzeszowPoland

Wines contain significant amounts of polyphenols which autoxidize upon contact with oxygen,producing hydrogen *** checked more than 40 samples of white and red wines finding,on average,production of small amounts of hydrogen peroxide within 3 h after the wines had contacted with air,though some samples did not produce detectable amounts of H_(2)O_(2).The increase in hydrogen peroxide concentration after 3-h incubation of wines after opening ranged from -3.09 to 6.60μ*** showed also the ability of hydrogen peroxide scavenging,which can be partly attributed to ***,the measured net production of hydrogen peroxide in wine is a result of the actual production and scavenging of hydrogen peroxide.

关键词： Wine Hydrogen peroxide Sulfite Polyphenols Autoxidation

Innovation,risk and finance paradigm from the polish perspective

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International Journal of Innovation Studies 2021年第3期5卷 107-112页

作者： Tomasz michalski Institute of Risk and Financial Markets SGH02-554 WarsawPoland

The aim of the paper is the presentation of the discussion on innovativeness,risk and paradigms changes with regards to paradigm in *** author starts with the description of globalization process that supported by science and technology affected socio-economic development but also intensified phenomena indicating symptoms of *** part focuses on the innovativeness and risk associated with innovativeness *** the Kuhn’s theory of paradigm is confronted with nowadays world of growing chaos with regards to *** conclusions is that innovativeness of societies is not determined by how much people representing the world of science but how the whole society refer to *** terms of financial paradigm a worrying phenomenon of disappearance of ethical principles is witnessed.

关键词： Innovativeness Risk Economy Paradigm Logos Mythos

Comparative analysis of the effects of gunpowder and plasma ignition in closed vessel tests

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Defence Technology（防务技术） 2019年第5期15卷 668-673页

作者： Radoslaw Trebinski Zbigniew Leciejewski Zbigniew Surma Jakub michalski Military University of Technology Department of Mechatronics and Aerospace

This paper presents the results of a comparative investigation into the effects of the ignition method on the ballistic properties of a single-base gun propellant,as determined via closed vessel *** gunpowder ignition and plasma jet ignition methods were used,and differences in the ignition time were *** influence of the ignition method on the dynamic vivacity is *** is shown that this influence is significant in the first phase of the combustion process,and with respect to the low values of the loading *** the second phase of the combustion process,and for large values of the loading density,the dynamic vivacity plots for the two ignition methods *** the burning law,close values of the exponent were obtained for the two ignition *** dynamic vivacity plots determined for plasma ignition reveal stronger dependence on the loading density than those determined for gunpowder *** conclusion is that plasma ignition is not a solution to the problems inherent to the process of determining the ballistic properties of propellants,which results in deviation of the burning process from the geometric burning law.

关键词： Closed vessel test Gun propellant Gunpowder ignition Plasma ignition

Geomorphologic Characteristics of Polygonal Features on Chloride-Bearing Deposits on Mars: Implications for Martian Hydrology and Astrobiology

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Journal of Earth Science 2019年第5期30卷 1049-1058页

作者： Binlong Ye Jun Huang Joseph michalski Long Xiao Planetary Science Institute School of Earth Sciences China University of Geosciences Wuhan 430074 China Department of Earth Sciences and Laboratory for Space Research University of Hong Kong Hong Kong 999077 China

Over 600 chloride-bearing deposits(chlorides) have been identified on the southern highlands of Mars. These chlorides have critical implications for hydrology and astrobiology: they are indicators of an evaporating super saturated solution, and they could have provided habitat environments for halophilic microorganisms and preserved organic matter. One of the prominent geomorphology characteristics of these chloridebearing regions is the polygonal features within them. The origin of these polygonal features is still in debate. In this study, we have surveyed 153 locations of chlorides using 441 high resolution imaging science experiment(Hi RISE) images to characterize the geomorphology of polygonal features. We identified 3 types of polygonal features of distinct geomorphologic characteristics: fractures, raised ridges, and transitional polygons between fractures and raised ridges. We evaluate previously proposed hypotheses of the formation of the polygonal features, and suggest that the 3 types of polygonal features are indicators of different stages of salt crust formation. Salt crust is usually formed through multiple groundwater activities, and it often occurs in playa environment on Earth. The unique hydrological and astrobiological implications of the chlorides with polygonal features make these deposits of high priority for future landed on and/or sample return exploration missions of Mars.

关键词： chlorides polygonal feature playa hydrology astrobiology Mars

Attaining the Steady State of the Nitriding Potential after a Change of NH_3 Atmosphere Flow Rate during the Gas Nitriding Process

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材料热处理学报 2004年第5期25卷 360-363页

作者： Jerzy michalski Jan Tacikowski Piotr Wach Tomasz Babul Nabil Tarfa Institute of Precision Mechanics Warsaw PolandInstitute of Precision Mechanics Warsaw PolandInstitute of Precision Mechanics Warsaw PolandInstitute of Precision Mechanics Warsaw PolandNitrex Metal Inc. 3474 Boul PoirierSt-Laurent Quebec CANADA.

In single and multi-stage nitriding processes, each stage is characterized by the following parameters: temperature and time, type and composition of incoming atmosphere, as well as the set value of the nitriding potential. In the case of an atmosphere composed of raw ammonia and dissociated ammonia (NH3 - NH3cKss), the set value of the nitriding potential can be achieved by a change of the incoming atmosphere make-up, while in the case of atmospheres comprising NH3 and NH} -N2 - by a change of the atmosphere flow rate. The time needed to reach a stabilized state, after the initiation of a change in the atmosphere gas mix can be assessed relatively easily. The problem is much more complex if we want to predict the time of reaching a new stabilized state following a change in atmosphere flow rate. The time of reaching stabilized state is, in this case, a complex function of the flow rate of the atmosphere which forces the potential change, and of temperature. This problem, in the case of the NH3 type atmosphere, is the subject of investigation in this work. Factors are discussed, affecting the rate at which stabilized state is reached by the system after the introduction of a disturbance, necessary to attain the required nitriding potential.

关键词：渗氮 NH3 大气特征稳定状态

Species diversity and population density affect genetic structure and gene dispersal in a subtropical understory shrub

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Journal of Plant Ecology 2012年第3期5卷 270-278页

作者： Xueqin Zeng Stefan G.michalski Markus Fischer Walter Durka UFZ-Helmholtz Centre for Environmental Research Department of Community Ecology(BZF)Theodor-Lieser-Strasse 4D-06120 HalleGermany Institute of Plant Sciences University of BernAltenbergrain 21CH-3013 BernSwitzerland

Aims The dispersal of pollen and seeds is spatially restricted and may vary among plant populations because of varying biotic interactions,population histories or abiotic *** gene dispersal is spatially restricted,it will eventually result in the development of spatial genetic structure(SGS),which in turn can allow insights into gene dispersal ***,we assessed the effect of habitat characteristics like population density and community structure on small-scale SGS and estimate historical gene dispersal at different spatial *** In a set of 12 populations of the subtropical understory shrub Ardisia crenata,we assessed genetic variation at 7 microsatellite loci within and among *** investigated small-scale genetic structure with spatial genetic autocorrelation statistics and heterogeneity tests and estimated gene dispersal distances based on population differentiation and on within-population *** was related to habitat characteristics by multiple *** Findings The populations showed high genetic diversity(He=0.64)within populations and rather strong genetic differentiation(F#ST=0.208)among populations,following an isolation-by-distance pattern,which suggests that populations are in gene flow–drift *** SGS was present within populations(mean Sp=0.027).Population density and species diversity had a joint effect on SGS with low population density and high species diversity leading to stronger small-scale *** of historical gene dispersal from between-population differentiation and from within-population SGS resulted in similar values between 4.8 and 22.9 *** results indicate that local-ranged pollen dispersal and inefficient long-distance seed dispersal,both affected by population density and species diversity,contributed to the genetic population structure of the *** suggest that SGS in shrubs is more similar to that of herbs than to trees and that in communities with

关键词： Ardisia crenata BEF China gene flow habitat effects spatial genetic structure

A framework for computer vision-based health monitoring of a truss structure subjected to unknown excitations

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Earthquake Engineering and Engineering Vibration 2023年第1期22卷 1-17页

作者： Mariusz Ostrowski Bartlomiej Blachowski bartosz Wójcik Mateusz Żarski Piotr Tauzowski Łukasz Jankowski Institute of Fundamental Technological Research Polish Academy of SciencesWarsawPoland Silesian University of Technology GliwicePoland Institute of Theoretical and Applied Informatics Polish Academy of SciencesGliwicePoland

Computer vision(CV)methods for measurement of structural vibration are less expensive,and their application is more straightforward than methods based on sensors that measure physical quantities at particular points of a ***,CV methods produce significantly more measurement ***,computer vision-based structural health monitoring(CVSHM)requires appropriate methods of damage assessment that are robust with respect to highly contaminated measurement *** this paper a complete CVSHM framework is proposed,and three damage assessment methods are *** first is the augmented inverse estimate(AIE),proposed by Peng et *** *** method is designed to work with highly contaminated measurement data,but it fails with a large noise provided by CV *** second method,as proposed in this paper,is based on the AIE,but it introduces a weighting matrix that enhances the conditioning of the *** third method,also proposed in this paper,introduces additional constraints in the optimization process;these constraints ensure that the stiffness of structural elements can only *** proposed methods perform better than the original *** latter of the two proposed methods gives the best results,and it is robust with respect to the selected coefficients,as required by the algorithm.

关键词： computer vision structural health monitoring physics-based graphical models augmented inverse estimate model updating non-negative least square method

Formation of transgressive anorthosite seams in the Bushveld Complex via tectonically induced mobilisation of plagioclase-rich crystal mushes

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Geoscience Frontiers 2016年第6期7卷 875-889页

作者： Wolfgang D.Maier bartosz T.Karykowski Sheng-Hong Yang School of Earth and Ocean Sciences Cardiff UniversityUK Oulu Mining School University of OuluFinland

The formation of anorthosites in layered intrusions has remained one of petrology＇s most enduring enigmas. We have studied a sequence of layered chromitite, pyroxenite, norite and anorthosite overlying the UG2 chromitite in the Upper Critical Zone of the eastern Bushveld Complex at the Smokey Hills platinum mine. Layers show very strong medium to large scale lateral continuity, but abundant small scale irregularities and transgressive relationships. Particularly notable are irregular masses and seams of anorthosite that have intrusive relationships to their host rocks. An anorthosite layer locally transgresses several 10 s of metres into its footwall, forming what is referred to as a ＂pothole＂ in the Bushveld Complex. It is proposed that the anorthosites formed from plagioclase-rich crystal mushes that originally accumulated at or near the top of the cumulate pile. The slurries were mobilised during tectonism induced by chamber subsidence, a model that bears some similarity to that generally proposed for oceanic mass flows. The anorthosite slurries locally collapsed into pull-apart structures and injected their host rocks. The final step was down-dip drainage of Fe-rich intercumulus liquid, leaving behind anorthosite adcumulates.

关键词： Anorthosite Layered intrusion Bushveld Complex South Africa Chromitite