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遗失的智慧

A Very Severe Obstructive Sleep Apnea Syndrome: In a Cause of Resistant Hypertension with One Sample Case

作者： (美.Schwartz barry)施瓦茨 (美)夏普

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World Journal of Cardiovascular Diseases 2021年第3期11卷 223-229页

作者： baldé Elhadj Yaya bah Mamadou bassirou barry Ibrahima Sory béavogui Mariama Sylla Ibrahima Sory baldé Mamadou Aliou Koné Alpha Diallo Mamadou Camara Abdoulaye baldé Siradiou baldé Mamadou Dadhi Dièye Ousmane Condé Mamady Cardiology Department of the Ignace Deen Hospital Conakry Guinea Cardiology Department of Donka Hospital Conakry Guinea Sakina Clinic in Dakar Dakar Senegal

When blood pressure values remain above the target in a hypertensive patient treated concomitantly with three anti-hypertensive drugs including a diuretic, maximum well-tolerated doses, this is a resistant arterial hypertension. In this case, it is advisable to look for a secondary cause such as a drug intake that influencing the blood pressure or the presence of obstructive sleeping syndrome (OSAS). We report a clinical case of a patient with a high cardiovascular risk at the age of 50, hypertensive and diabetic, with dyslipidemia and obesity. He was on anti-hypertensive triple therapy at an optimal dose. Her diabetes was balanced with 6.4% glycated hemoglobin. Dyslipidemia has being treated. Despite healthy diet including a low sodium diet and weight loss, blood pres- sure target was not reached. With self-measurement, the mean arterial pressure was 180/110 mmHg and on ABPM it was 167/113 mmHg. The ventilatory polygraphy finds a severe OSA with an IAH = 56.6. Treatment with PCP (Con- tinuous positive pressure) allowed this patient to control blood pressure. The search for OSA should be systematic in face of resistant hypertension, in par- ticular in overweight or obese patients.

关键词： Obstructive Sleep Apnea Syndrome (OSAS) Resistant Hypertension Continuous Positive Airway Pressure (CPAP)

Myocardial Perfusion Abnormalities in Patients with Hereditary Hypertrophic Cardiomyopathy: A Study of Three Cases and Review of the Literature

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World Journal of Cardiovascular Diseases 2023年第6期13卷 289-296页

作者： Ngardjibem Djita Ibrahima Sory Sylla Mamadou bassirou bah Felix Collard Sana Samoura Mamadou Aliou baldé Souleymane Diakité Ibrahima Sory barry Alpha Koné Elhadj Yaya baldé Mariame béavogui Mamadou Dadhi baldé Philippe Chevalier Department of Cardiology Alen&ccedilon Hospital Alen&ccedilon France Department of Cardiology CHU Ignace Deen Conakry Guinea Department of Cardiology Sino-Guinean Friendship Hospital Conakry Guinea Department of Cardiology CHU Lyon Lyon France

Introduction: Hypertrophic cardiomyopathy (HCM) belongs to the very heterogeneous group of cardiomyopathies. This study aimed to study myocardial perfusion abnormalities on scintigraphy and assess the risk of sudden death from ventricular arrhythmia in hereditary sarcomeric HCM. Patients and Methods: This is a retrospective and prospective descriptive study over 18 months (January 01, 2021, to July 31, 2022) on the records of patients over 18 with the diagnosis of hypertrophic sarcomeric cardiomyopathy with or without ventricular rhythm disorders and who have undergone myocardial scintigraphy. Results: Three patients were included. The average age of our patients was 66 years old. Dyspnea is the primary symptomatology found in our patients. One patient presented with syncope and unsustained ventricular tachycardia. His risk score for sudden death from ESC at five years is estimated at 6.45%, and the patient received an ICD in primary prevention. The average sudden death risk score of our patients was 3.78%. The mean LV wall thickness was 20 mm. The mean maximum left intraventricular gradient was 39 mmHg. Myocardial fibrosis was present in all our patients. Myocardial scintigraphy was normal in all cases. Conclusion: Hypertrophic cardiomyopathy is a very heterogeneous group of cardiomyopathies. The rhythmic risk is multifactorial and constitutes a significant prognostic factor.

关键词： Hypertrophic Cardiomyopathy Myocardial Scintigraphy Sudden Death Ven-tricular Arrhythmia

小芯径硫系玻璃光纤的制备及其非线性光学应用

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无机材料学报 2016年第2期31卷 180-184页

作者：郭威张斌翟诚诚祁思胜余懿杨安平李雷杨志勇王荣平唐定远陶光明 Luther-Davies barry 江苏省先进激光材料与器件重点实验室江苏师范大学物理与电子工程学院徐州221116 Centre for Ultra-high-bandwidth Devices for Optical Systems(CUDOS) Laser Physics CentreResearch School of Physics and EngineeringAustralian National UniversityCanberraACT 2600Australia CREOL The College of Optics&PhotonicsUniversity of Central FloridaOrlandoFlorida 32816USA

通过动态蒸馏提纯技术制备了高纯Ge-As-Se和Ge-As-S硫系玻璃。采用两步棒管法拉制了以Ge-As-Se玻璃为纤芯、Ge-As-S玻璃为包层的小芯径阶跃折射率光纤,并使用飞秒激光抽运光纤测试了超连续谱的产生。以Al和GaCl_3分别作为除氧剂和C/H纯... 详细信息

通过动态蒸馏提纯技术制备了高纯Ge-As-Se和Ge-As-S硫系玻璃。采用两步棒管法拉制了以Ge-As-Se玻璃为纤芯、Ge-As-S玻璃为包层的小芯径阶跃折射率光纤,并使用飞秒激光抽运光纤测试了超连续谱的产生。以Al和GaCl_3分别作为除氧剂和C/H纯化剂可以有效消除玻璃中的C、H和O杂质。制备的Ge As Se/Ge As S光纤在2~9μm波段表现出优异的传输性能,光纤数值孔径约为1.3;采用重复频率为10.5 MHz、脉冲宽度为320 fs、中心波长为4.0μm、峰值功率为4.6 k W激光抽运长度为22 cm、芯径为6μm的光纤,获得了覆盖1.9~8.2μm、光谱平坦度为±10 d b、平均功率为4.5 m W的超连续谱。

关键词：非线性光学硫系玻璃光纤中红外超连续谱产生

Cardio-Renal Syndrome: Epidemiological, Clinical, Paraclinical, Etiological Aspects and Prognostic Factors in the Cardiology Department of the CHU Ignace Deen in Conakry

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World Journal of Cardiovascular Diseases 2023年第4期13卷 189-197页

作者： barry Ibrahima Sory Diakité Foussény Fofana Fatoumata baldé El Hadj Yaya bah Mamadou bassirou Mariama béavogui Mariam Soumaoro Morlaye Camara Abdoulaye Samoura Aly Koïvogui Diarra Koïvogui Kokoulo Diallo Salématou baldé Mamadou Dadhi Cardiology Department CHU Ignace Deen Conakry Guinea CHU Donka National Hemodialysis Center Conakry Guinea

Introduction: Heart and kidney diseases are common among patients admitted to hospital and they coexist in a significant number of cases. The interactions between the cardiovascular system and the kidney have been known and described for many years and have led to the description of cardio-renal syndrome. The objective of this study was to determine the frequency;to describe the clinical, etiological and prognostic aspects of acute renal failure in patients hospitalized for chronic congestive heart failure. Method: This was a descriptive retrospective study from January 2, 2018 to December 31, 2022. Included in this study were all the complete records of patients hospitalized for chronic congestive heart failure with serum creatinine ≥120 μmol/I. We’re not included in this study, incomplete files, records of patients hospitalized for other pathologies, records of patients hospitalized for chronic congestive heart failure with normal renal function. Our study variables were qualitative and quantitative divided into clinical, paraclinical and prognostic data. Our data were analyzed using the EPI-info 7.***.2.6 software. Data entry and presentation were carried out using Word, Excel and PowerPoint from the 2016 Office Pack. Results: We collected 830 files of which 114 met our selection criteria, a frequency of 13.73%. The mean age of the patients was 47 ± 19 years. The F/M sex ratio was 1.23. The dominant etiologies were hypertension followed by diabetes with respectively 60.5% and 23.7%. Toxic factors including tobacco accounted for 7.9% of cases. Dyspnea accounted for 86.8%. Most of our patients were grade 3 or 36% based on systolic blood pressure on admission with an average of 164.16 ± 33.95 mmHg and an average diastolic blood pressure of 93.24 ± 20.40 mmHg. biologically, the serum creatinine revealed a high frequency of 201 - 400 μmol/l (33% of cases) with an average value of 586.49 ± 631.44 μmol/l with the extremes 2.960 and 2448.68 μmol/I. Anemia was moderate in 3

关键词： Cardio-Renal Syndrome Ignace Deen

Takayasu Disease Revealed by Arterial Hypertension in a 47-Year-Old Man

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World Journal of Cardiovascular Diseases 2023年第7期13卷 341-348页

作者： bah Mamadou bassirou baldé Thierno Hamidou Wann Thierno Amadou baldé Elhadj Yaya baldé Aissatou Tiguidanké Koné Alpha Doumbouya Amadou Diouldé Diallo Hafsatou barry Ibrahima Sory Samoura Sana Diakité Souleymane béavogui Mariam baldé Mamadou Dadhi Cardiology Department Ignace Deen Hospital Conakry Guinea Department of Imaging Ignace Deen Hospital Conakry Guinea Department of Internal Medicine Donka Hospital Conakry Guinea Cardiology Department Donka Hospital Conakry Guinea

Takayasu disease is a chronic vasculitis of the large vessels. It is rare in sub- Saharan Africa and probably under-diagnosed. Arterial hypertension (AH) is a frequent finding. We report the case of a 46-year-old man with Takayasu disease revealed by hypertension. The American College of Rheumatology (ACR) criteria were used for diagnosis, with 4 out of 6 criteria. Echodoppler and angioscanner showed signs of left subclavian stenosis and circumferential, regular arterial thickening. He had a biological inflammatory syndrome. He was treated with prednisone and amlodipine. After 6 months of follow-up, he was diagnosed with tuberculosis and put on anti-tuberculosis treatment.

关键词： Takayasu Disease Hypertension Man

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教你一个哮喘长期治疗方案

实用乡村医生杂志 2003年第1期10卷 37-39页

作者： Robert b.Mellins Dadid Evans Noreen Clark barry Zimmerman Sandra Wiesemann 刘嘉嘉 Columbia University College of Physicians and Surgeons Columbia University School of Public Health NewYorkNewYorkPH.D. University of Michigan School of Public Health City University of New York Graduate School and University Center Medical Health Research Association of NewYork NewYorkNewYorkR.N.M.P.H. 中国医科大学84期日文2班沈阳110001

据了解,目前约有40%～50%的医嘱得不到患者的正确执行,而通过医生与患者进行有效的沟通,可以提高患者对用药方案的依从性.本文介绍了一种针对哮喘患者制定的长期治疗方案,并强调了治疗方案涉及患者及其家属从而提高其依从性的重要性,同... 详细信息

据了解,目前约有40%～50%的医嘱得不到患者的正确执行,而通过医生与患者进行有效的沟通,可以提高患者对用药方案的依从性.本文介绍了一种针对哮喘患者制定的长期治疗方案,并强调了治疗方案涉及患者及其家属从而提高其依从性的重要性,同时利用比较容易理解和运用的图表形式使治疗方案简单易行.该方案要求医生向患者提供治疗指导,患者或其家属能够根据每次发病的病情自行调整治疗方案.

关键词：哮喘治疗方案症状预防

Ankylosing Spondylitis in a West African Hospital

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Open Journal of Rheumatology and Autoimmune Diseases 2023年第1期13卷 8-16页

作者： Abdoulaye barry Oumar Diouhé bah Adama bah Mamadou Lamine Diallo Kaba Condé Samba Frein Condé Aly badra Kamissoko Rheumatology Department of the National Ignace Deen Hospital in Conakry Conakry Guinea biomar 24 Medical Laboratory Conakry Guinea

Introduction: Ankylosing spondylitis (AS) is an inflammatory rheumatic disease characterized by predominant axial and peripheral (enthesitis, sacroiliitis) involvement affecting young subjects aged 30 to 40 years, 80% to 98% of cases are associated with HLA-b27. Objective: To determine the epidemiological profile of ankylosing spondylitis in the rheumatology department of the Ignace Deen National Hospital in Conakry (Guinea). Materials and Methods: This was a descriptive cross-sectional study carried out within the said department over a period of 18 months from July 1, 2018 to December 31, 2020, including all patients seen in consultation and/or hospitalized in the department in which the diagnosis of ankylosing spondylitis had been retained according to the modified New York criterion. The parameters studied were sociodemographic, clinical, paraclinical and therapeutic. Result: We collected 73 cases or 4.1% of ankylosing spondylitis out of a total of 1781 patients seen during the study period. The male gender was represented with 54.8% for a sex ratio of 1.2 M/F. The average age of our patients was 32.18 ± 12.44 years with extremes ranging from 17 to 54 years. Axial involvement was present in 89.9% of cases with a lumbar predominance (95.2%), followed by the sacroiliac seat (35.5%), cervical (14.5%) and dorsal at 4.8%. The pain was chronic in 93.2% of cases. The most common drug treatment was taking analgesics and NSAIDs (100%) followed by cortisone infiltration (41.1%), corticosteroids (30%), and physiotherapy (21.9%). Ankylosing spondylitis represents 83% of spondyloarthritis followed by undifferentiated spondyloarthritis (9.1%) and juvenile spondylitis (3.4%) were the most common conditions.

关键词： Ankylosing Spondylitis Rheumatology Ignace Deen Guinea

In situ determination of U-Pb ages and Sr-Nd-Hf isotopic constraints on the petrogenesis of the Phalaborwa carbonatite Complex,South Africa

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In situ determination of U-Pb ages and Sr-Nd-Hf isotopic con...