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Evidence of a conservative gait strategy in athletes with a history of concussions

journal of Sport and Health Science 2016年第4期5卷 417-423页

作者： Thomas A.Buckley Srikant Vallabhajosula jessie R.Oldham barry A.Munkasy Kelsey M.Evans David A.Krazeise Caroline j.Ketcham Eric E.Hall Department of Kinesiology and Applied Physiology University of Delaware Department of Physical Therapy Education Elon University Department of Health and Kinesiology Georgia Southern University Department of Intercollegiate Athletics Stetson University Department of Exercise Science Elon University

Background：A history of 3 or more concussions is frequently associated with numerous short-and long-term *** in postural control are a known acute consequence of concussion;however,limited evidence exists on the effects of multiple concussions on *** purpose of this study was to assess gait stepping characteristics in collegiate aged student-athletes based on concussion ***：There were 63 participants divided into 3 even groups based on concussion history：≥3 concussions,1–2 concussions,and 0 *** participants completed 10 trials of gait on a 4.9 m instrumented *** dependent variables of interest included both gait stepping characteristics（step velocity,length,and width,double support time,and the percentage of the gait cycle in stance） and coefficien of variability（CoV） measures（step length,time,and width）.The gait stepping characteristics were compared firs with a MANOVA with follow-up 1-way ANOVAs and Tukey post hoc tests as *** Co V measures were compared with 1-way ANOVAs and Tukey post hoc ***：There were main effects for group for step velocity,length,width,and double support ***,the 0 concussion group displayed typical healthy young gait parameters and performed significant y better than either concussion *** 0 concussion group had a significant y greater step length Co V,but there were no differences in the step time or width Co ***：This findin provides evidence of subtle impairments in postural control during gait among individuals with prior history of concussion which could be an early indicator of future neurological deficiencies The limited difference in the variability measures is consistent with prior static stance studies and could suggest the individuals constrain their motor systems to reduce *** together,these findi gs suggest a conservative gait strategy which is adopted by individuals with a history of concussions.

关键词： Balance Brain injury Gait performance Locomotion Mild traumatic Postural control Postural stability Variability

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现代深海砂的碎屑模式及其与构造环境的关系:首次尝试

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地球与环境 1983年第4期 34-38页

作者： Renzo Valloni ,j. barry Maynard ,高计元

引言砂岩岩石学是阐明盆地历史的一个潜在的有力工具。它常用于浅水陆棚和大陆环境中的现代砂岩和古代砂岩的研究。然而奇怪的是,对深海砂样的研究几乎只是依赖于古代岩石样品,例如,仅在近年来才对深海钻探计划(DSDP)的岩心砂样进行了... 详细信息

引言砂岩岩石学是阐明盆地历史的一个潜在的有力工具。它常用于浅水陆棚和大陆环境中的现代砂岩和古代砂岩的研究。然而奇怪的是,对深海砂样的研究几乎只是依赖于古代岩石样品,例如,仅在近年来才对深海钻探计划(DSDP)的岩心砂样进行了岩石学研究,而且主要是以逐点为基础的。因此,为了了解古代深海砂,就需要有一个现代沉积物的可靠基准。在本文中,我们试图利用我们在深海砂方面的工作结果并与前人工作进行对比,初步提出这种数据基准。

关键词：深海砂构造环境长石质岩石学盆地地质构造碎屑

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大气、天气和气候

大气、天气和气候

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1982年

作者：巴里（R.G.barry）乔利（R.j.Chorley）施尚文等译

本书深入浅出地阐明了天气学与气候学的基本原理和最新成果.

ISBN: (纸本)12010·030

本书深入浅出地阐明了天气学与气候学的基本原理和最新成果.

关键词：气象学

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Changes in otolaryngology application requirements and match outcomes:Are we doing any better?

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World journal of Otorhinolaryngology-Head and Neck Surgery 2023年第2期9卷 144-152页

作者： Emma De Ravin Ariel S.Frost Neal R.Godse Amber D.Shaffer Noel jabbour barry M.Schaitkin jason Newman Leila j.Mady Department of Otorhinolaryngology-Head and Neck Surgery University of Pennsylvania Health SystemPhiladelphiaPennsylvaniaUSA Head and Neck Institute Cleveland ClinicClevelandOhioUSA Division of Pediatric Otolaryngology Children's Hospital of Pittsburgh of UPMCPittsburghPennsylvaniaUSA Department of Otolaryngology University of Pittsburgh Medical CenterPittsburghPennsylvaniaUSA Department of Otolaryngology-Head and NeckSurgery Medical Universityof South CarolinaCharlestonSouth CarolinaUSA MUSC Hollings Cancer Center CharlestonSouthCarolinaUSA Department of Otolaryngology-Head and Neck Surgery Thomas Jefferson UniversityPhiladelphiaPennsylvaniaUSA Cancer Risk and Control Program of Excellence Sidney Kimmel Cancer CenterPhiladelphiaPennsylvaniaUSA

Objectives:Otolaryngology-specific requirements were piloted to minimize applicant and program *** investigated the impact of introducing and then removing these requirements on Match ***:2014-2021 National Resident Matching Program?data were *** primary outcome was the impact of Otolaryngology Resident Talent Assessment(ORTA;prematch 2017,postmatch 2019)and Program-Specific Paragraph(PSP;implemented 2016,optional 2018)on applicant numbers and match *** survey analysis assessed candidate perceptions of PSP/***:Applicant numbers declined significantly during PSP/ORTA(18.9%;p=0.001).With the optional PSP and postmatch ORTA,applicant numbers increased significantly(39.0%;p=0.002).Examined individually,mandatory PSP was associated with a significant decline in applicants(p=0.007),whereas postmatch ORTA was associated with significant increases in applicants(p=0.010).ORTA and PSP negatively impacted the decision to apply to otolaryngology in 59.8%and 51.3%of applicants,***,match rate success improved significantly from 74.8%to 91.2%during PSP/ORTA(p=0.014),followed by a significant decline to 73.1%after PSP was made optional and ORTA moved to postmatch(p=0.002).Conclusions:ORTA and PSP correlated with decreased applicant numbers and increased match rate *** programs seek ways to remove barriers to applying to otolaryngology,the potential consequences of an increasing pool of unmatched candidates must also be considered.

关键词： academic success internship and residency medical students otolaryngology surveys and questionnaires

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Late Mesozoic and Cenozoic thermotectonic evolution along a transect from the north China craton through the Qinling orogen into the Yangtze craton,central China

Late Mesozoic and Cenozoic thermotectonic evolution along a ...

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中国科学院地质与地球物理研究所2006学术年会

作者： Asaf Raza Kyoungwon Min barry P.Kohn Peter W.Reiners Richard A.Ketcham Andrew j.W.Gleadow School of Earth Sciences University of MelbourneMelbourneAustralia Department of Geology and Geophysics Yale UniversityNew HavenConnecticutUSA Department of Geological Sciences University of Texas at AustinAustinTexasUSA

Cretaceous and Cenozoic reactivation of the Triassic Qinling-Dabie orogen between the north China and Yangtze cratons resulted from the combined effects of Pacific subduction-back-arc extension in east China and collisions in west *** report new apatite fission track and apatite and zircon(U-Th)/He data from east Qinling along a >400-km-long N-S transect from Huashan through the Qinling orogen to *** ages show a general pattern of younging *** major cooling phases are defined by modeling the multiple thermochronologic data *** first phase occurred locally in the North and South Qinling during the late Triassic to early jurassic,following heating associated with the Triassic Yangtze subduction and exhumation of the Wudang metamorphic core complex on the cratonal edge.A second phase represents regional exhumation between 100 and 60 Ma,coeval with rifting marked by the Late Cretaceous-Eocene(K2-E) red bed deposition in eastern China and possibly indicating a link with Pacific subduction-back-arc extension in eastern China;however,it may also have been superimposed by eastward tectonic escape resulting from the Lhasa-West Burma-Qiangtang-Indochina *** third cooling phase was initiated at 5 Ma exclusively in the north Qinling and in the footwall of the graben-bounding normal fault of the Weihe graben in the Lesser *** suggest the third phase was related to reactivation of the Qinling fault system as a result of eastward tectonic escape imposed by the India-Asia collision at 0 Ma.

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新致病基因在颅缝早闭Crouzon综合征中的初步机制研究

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组织工程与重建外科杂志 2012年第5期8卷 256-263页

作者：杨娴娴 jodie T Hatfield Susan j Hinze 穆雄铮 Peter j Anderson barry C Powell 上海交通大学医学院附属第九人民医院整复外科上海市200011 澳大利亚颅颌面外科中心阿德莱德妇女儿童健康研究中心复旦大学医学院附属华山医院整形外科上海市200040

目的研究Rbp4(Retinol binding protein 4)、Gpc3(Glypican family of growth factor binding protein 3)、C1qtnf3(Collagenous repeat-containing sequence of 26 KDa protein)等新致病基因在颅缝早闭症中的发病机制,为疾病非手术治疗奠定理论基础。方法以Crouzon综合征Fgfr2cC342Y/+小鼠为实验模型,应用MicroCT和组织学染色,研究小鼠颅缝闭合模式;以Fgfr2cC342Y/+模型,RT-qPCR研究Rbp4、Gpc3、C1qtnf3等新致病基因的表达差异,初步探讨其在颅缝闭合过程中的调控作用;以体外培养的Fgfr2cC342Y/+小鼠颅缝细胞为模型,研究基因突变动物细胞增殖与代谢改变。结果获得Fgfr2cC342Y/+小鼠后额缝、冠状缝、人字缝、矢状缝等颅缝闭合模式,随颅骨发育、颅缝闭合,OC(Osteocalcin)、ALP(Alkalinephosphatase)表达增加,目的基因Rbp4、Gpc3、C1qtnf3表达下降,Msx2(Muscle segment homeobox gene 2)表达增加,杂合子与野生型小鼠之间均存在显著统计学差异,与前期人颅缝组织Microarray研究结果一致。Gpc1(Glypican family ofgrowth factor binding protein 1)、FliI(Flightless I)在颅缝闭合中的表达较恒定,野生型与杂合子之间未见明显统计学差异。体外培养Fgfr2cC342Y/+小鼠颅缝细胞,CellTiter96 MTS和Quant-iT Picogreen dsDNA细胞增殖与代谢分析结果显示,Fgfr2功能获得性突变可促进冠状缝细胞的增殖,从而导致成骨增加,颅缝早闭。结论 Fgfr2cC342Y/+模型新致病基因表达趋势与前期人颅缝组织Microarray研究结果一致,Rbp4、Gpc3、C1qtnf3可能在颅缝早闭中具重要调控作用。

关键词：颅缝早闭症 Fgfr2cC342Y/+小鼠 Crouzon综合征 RT-qPCR 微量CT Rbp4 Gpc3 Clqtnf3

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贝多芬钢琴奏鸣曲全集（35首）卷3

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丛书名：英国皇家音乐学院联合委员会提供版权

2010年

作者：巴里·库珀（barry Cooper）编订

本书是贝多芬35首钢琴奏鸣曲的新版本, 也是目前世界上最新的版本, 编者研究了之前的所有版本并且编写了评注, 这一版本又补遗了3首奏鸣曲, 成为较为权威的35首贝多芬奏鸣曲全集。

ISBN: (纸本)9787807515524

关键词：钢琴谱近代德国奏鸣曲选集

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贝多芬钢琴奏鸣曲全集（35首）卷2

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丛书名：英国皇家音乐学院联合委员会提供版权

2010年

作者：巴里·库珀（barry Cooper）编订

本书包括：《贝多芬钢琴奏鸣曲全集(35首)(卷1)》、《贝多芬钢琴奏鸣曲全集(35首)(卷2)》和《贝多芬钢琴奏鸣曲全集(35首)(卷3)》。《贝多芬钢琴奏鸣曲全集(35首)(套装共3册)(精)》内容简介：由贝多芬权威巴里·库珀教授编订的本版《贝... 详细信息

ISBN: (纸本)9787807515517

本书包括：《贝多芬钢琴奏鸣曲全集(35首)(卷1)》、《贝多芬钢琴奏鸣曲全集(35首)(卷2)》和《贝多芬钢琴奏鸣曲全集(35首)(卷3)》。《贝多芬钢琴奏鸣曲全集(35首)(套装共3册)(精)》内容简介：由贝多芬权威巴里·库珀教授编订的本版《贝多芬钢琴奏鸣曲全集(35首)》，深入浅出，

关键词：钢琴谱近代德国奏鸣曲选集

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颅缝早闭症相关实验荧光定量PCR内参基因的选择研究

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组织工程与重建外科杂志 2012年第3期8卷 140-145页

目的探讨用于颅缝早闭症相关实验的荧光定量PCR的最佳内参基因。方法应用与颅骨成骨、颅缝闭合相关的3组实验标本,分别为:Fgfr2cC342Y/+Crouzon综合征小鼠颅缝组织、颅缝早闭患者体外培养颅缝原代细胞和体外培养的小鼠Kusa 4b 10成骨细... 详细信息

目的探讨用于颅缝早闭症相关实验的荧光定量PCR的最佳内参基因。方法应用与颅骨成骨、颅缝闭合相关的3组实验标本,分别为:Fgfr2cC342Y/+Crouzon综合征小鼠颅缝组织、颅缝早闭患者体外培养颅缝原代细胞和体外培养的小鼠Kusa 4b 10成骨细胞株。以常用的候选管家基因作为研究对象,利用geNorm软件对RT-qPCR结果进行比较分析,以筛选出在不同组织细胞中表达最为稳定的管家基因作为内参。结果Fgfr2cC342Y/+小鼠颅缝组织,Cyc1-Gapdh-Canx为最佳组合;颅缝早闭症患者体外培养颅缝原代细胞,18S rRNA和ATP5B为最佳组合;体外培养的小鼠Kusa 4b10成骨细胞株,18S rRNA和Canx为最佳组合。选择不同内参基因对目的基因RT-qPCR的结果影响显著。结论在设计RT-qPCR实验之前,应针对所选择的标本类型与种类进行管家基因稳定性分析,以增加结果的可信度。

关键词：颅缝早闭症荧光定量聚合酶链反应geNorm分析

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Detrital zircon(U-Th)/He thermochronometry of the Mesozoic Daba Shan Foreland Basin,central China:Evidence for timing of post-orogenic denudation

Detrital zircon(U-Th)/He thermochronometry of the Mesozoic D...

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中国科学院地质与地球物理研究所2012年度（第12届）学术年会

作者： Yuntao Tian Nansheng Qiu barry P.Kohn Chuanqing Zhu Shengbiao Hu Andrew j.W.Gleadow Brent I.A.Mclnnes State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of Sciences State Key Laboratory of Petroleum Resource and Prospecting China University of Petroleum CSIRO Exploration & Mining KensingtonWestern AustraliaAustralia

The timing of the transition of a peripheral foreland basin from underfilled to overfilled provides important insights into the post-orogenic dynamics of its coupled orogenic *** information is lacking in the Mesozoic foreland basins surrounding the Qinling Orogen,central China,such as the Daba Shan Foreland Basin(DSFB),the northeastern part of the Sichuan *** an effort to constrain the timing of maximum burial and onset of denudation,we report detrital zircon(U-Th)/He(ZHe) data from four deep boreholes in the *** show that ZHe ages from the oldest foreland basin formations(Upper Triassic-lower Middle jurassic) are mostly younger than their depositional age,whereas non-reset ZHe ages characterize younger *** suggests that the oldest strata attained maximum temperatures between -130℃and 200℃(ZHe partial retention zone),which is consistent with previous independent paleotemperatures (organic matter reflectance and illite crystallinity) reported in two of the boreholes and another nearby. The fully reset ages apparently show the youngest peaks at -80 Ma and -100 Ma,which are interpreted as the minimum constraints on the timing of maximum basinal burial and subsequent *** that the regional deposition has lasted to Aptian time,it is proposed that the onset of the basin exhumation in the DSFB started at Aptian-Albian time(～100-125 Ma),heralding the termination of regional tectonic shortening in the hinterland(Southern Qinling).

关键词： Daba Shan Foreland Basin Sichuan Basin Southern Qinling Zircon(U-Th)/He Denudation Post-orogenic evolution

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