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Clinical, Therapeutic and Evolutionary Profiles of Hypertensive Emergencies in the Cardiology Department of the Ignace Deen National Hospital (Conakry)

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World Journal of Cardiovascular Diseases 2023年第12期13卷 827-836页

作者： Balde Elhadj Yaya Bah Mamadou Bassirou barry ibrahima sory Kone Alpha Keita Fatoumata Binta Soumaoro Morlaye Toure Aboubacar Doumbouya Amadou Dioulde Sylla ibrahima sory Diakite Souleymane Balde Mamadou Dadhi Cardiology Department of the Ignace Deen Hospital Conakry Guinea

Introduction: Hypertensive emergencies are a reality in the cardiology department of the Ignace Deen National Hospital. The aim of this study was to determine the clinical, therapeutic and evolutionary profile of hypertensive emergencies in the cardiology department of the Ignace Deen National Hospital. Methods: This was a longitudinal descriptive study of patients admitted to the cardiology department of the Ignace Deen National Hospital for hypertensive emergencies, over a period of six (6) months from 1 October 2020 to 31 March 2021. Results: Among the 638 patients admitted to the cardiology department during the study period, 102 cases of hypertensive emergencies were identified, representing a frequency of 15.99%. The mean age of the patients was 56.65 ± 13.33 years, with extremes of 23 and 90 years, and the sex ratio was 1.91 in favour of men. The associated cardiovascular risk factors were: age (76.47%), smoking (41.18%), sedentary lifestyle (31.37%), obesity (16.67%), dyslipidaemia (12.75%), diabetes (11.76%) and excessive alcohol consumption (11.76%). The various clinical pictures found were: acute pulmonary oedema 39 cases (38.23%), acute coronary syndrome 31 cases (30.39%), stroke 17 cases (16.67%), hypertensive encephalopathy 11 cases (10.78%), acute renal failure 3 cases (2.94%) and aortic dissection 1 case (0.98%). The drugs used on admission were calcium antagonists (Nicardipine 10mg) in 58 cases (56.86%), diuretics (Furosemide 20mg) in 44 cases (43.13%), nitrates (Risordan 20mg) in 39 cases (38.23%) and beta-blockers in 31 cases (30.39%). In terms of outcome, 88 (86.27%) patients had improved. However, 12 (11.76%) deaths were recorded. Conclusion: Hypertensive emergencies are a worrying condition with a high prevalence in the cardiology department of the Ignace Deen National Hospital.

关键词： Emergency Hypertension Prevalence National Hospital Ignace Deen

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Family Dyslipidemia Revealed by a Cornean Bow in a Guinean

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World Journal of Cardiovascular Diseases 2020年第7期10卷 455-459页

作者： Bah Mamadou Bassirou Balde El Hadj Yaya Balde Alpha ibrahima Beavogui Mariame Camara Abdoulaye barry ibrahima sory Balde Mamadou Aliou Sylla ibrahima sory Kone Alpha Ngaide Alhassane Aliou Mamy Adrien Balde Mamadou Dadh Ignace Deen National Hospital Cardiology Department Conakry Republic of Guinea Department of Ophthalmology Department of the Armed Forces Conakry Republic of Guinea Cardiology Department of Donka National Hospital Conakry Republic of Guinea Department of Hospital Cardiology of Grand Yoff Dakar Senegal

Object: The aim of this study was to describe a familial dyslipidemia revealed by a corneal arch. Familial hypercholesterolemia is a rare and severe hereditary dyslipidemia with an exceptional homozygous form. He was a 43-year-old patient admitted with visual disturbance, xanthomatous papule and orange coloring at the level evolving for 5 years, no personal history of cardiovascular disease, having a family history of lipid disorders in siblings, as a cardiovascular risk factor: age over 50 and the male gender, normal cardio pulmonary examination, blood pressure at 120/80 mmhg, heart rate 78 bpm, in whom the ophthalmological examination shows a yellowish spot on the cornea (Figure 1). We report the case of familial dyslipidemia revealed by a corneal spot in Guinea.More recent studies increasingly suggest that it is much more widespread than previously thought: 1/200 to 1/400. Familial dyslipidemia is a rare and severe metabolic abnormality. It should be screened as early as possible like any other cardiovascular risk factor for atheroma to avoi

关键词： Corneal Arch Familial Dyslipidemia Guinea

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A Very Severe Obstructive Sleep Apnea Syndrome: In a Cause of Resistant Hypertension with One Sample Case

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World Journal of Cardiovascular Diseases 2021年第3期11卷 223-229页

作者： Baldé Elhadj Yaya Bah Mamadou Bassirou barry ibrahima sory Béavogui Mariama Sylla ibrahima sory Baldé Mamadou Aliou Koné Alpha Diallo Mamadou Camara Abdoulaye Baldé Siradiou Baldé Mamadou Dadhi Dièye Ousmane Condé Mamady Cardiology Department of the Ignace Deen Hospital Conakry Guinea Cardiology Department of Donka Hospital Conakry Guinea Sakina Clinic in Dakar Dakar Senegal

When blood pressure values remain above the target in a hypertensive patient treated concomitantly with three anti-hypertensive drugs including a diuretic, maximum well-tolerated doses, this is a resistant arterial hypertension. In this case, it is advisable to look for a secondary cause such as a drug intake that influencing the blood pressure or the presence of obstructive sleeping syndrome (OSAS). We report a clinical case of a patient with a high cardiovascular risk at the age of 50, hypertensive and diabetic, with dyslipidemia and obesity. He was on anti-hypertensive triple therapy at an optimal dose. Her diabetes was balanced with 6.4% glycated hemoglobin. Dyslipidemia has being treated. Despite healthy diet including a low sodium diet and weight loss, blood pres- sure target was not reached. With self-measurement, the mean arterial pressure was 180/110 mmHg and on ABPM it was 167/113 mmHg. The ventilatory polygraphy finds a severe OSA with an IAH = 56.6. Treatment with PCP (Con- tinuous positive pressure) allowed this patient to control blood pressure. The search for OSA should be systematic in face of resistant hypertension, in par- ticular in overweight or obese patients.

关键词： Obstructive Sleep Apnea Syndrome (OSAS) Resistant Hypertension Continuous Positive Airway Pressure (CPAP)

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Arterial and Venous Thrombosis following Vaccination against COVID-19 with Astra-Zeneca Vaccine Revealing Thrombophilia

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World Journal of Cardiovascular Diseases 2023年第4期13卷 198-204页

作者： Bah Mamadou Bassirou Doumbouya Amadou Dioulde Balde Mamadou Aliou Balde Thierno Hamidou Sylla ibrahima sory Balde Elhadj Yaya Kone Alpha barry ibrahima sory Samoura Sana Beavogui Mariam Diakité Souleymane Balde Mamadou Dadhi Cardiology Department Ignace Deen Hospital Conakry Guinea Imaging Department Ignace Deen Hospital Conakry Guinea

Vaccination against COVID-19 is the most recognised means of containing the pandemic. Vaccines are not without side effects, particularly vascular thrombosis. But before blaming the vaccines, a thorough assessment of thrombotic risk factors is necessary. We report a case of arterial and venous thrombosis after vaccination with AstraZeneca revealing an exaggeration of factor VIII in a 37-year-old female patient. The angioscanner showed a venous thrombosis of the right subclavian, a pulmonary embolism and the presence of a thrombus in the aorta. The biology was in favour of a high level of factor VIII. The patient was treated with an antivitamin K, and the clinical evolution was favourable.

关键词： Thrombophilia Thrombosis Vaccine AstraZeneca

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Epidemiological, Clinical and Therapeutic Aspects of Arterial Hypertension at the General Medicine Department of Nzerekore Regional Hospital

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World Journal of Cardiovascular Diseases 2021年第11期11卷 533-538页

作者： Beavogui Mariama Balde Elhadj Yaya Doumbouya Idrissa barry ibrahima sory Samoura Aly Camara Abdoulaye Bah Mamadou Bassirou Mariama Sylla ibrahima sory Balde Mamadou Dadhi Bah Abdoul Mazid Mariama Kone Alpha Balde Mamadou Aliou Conde Mamady Cardiology Department Ignace Deen National Hospital Conakry Guinea Department of Neurology Ignace Deen National Hospital Conakry Guinea Cardiology Department Donka National Hospital Conakry Guinea

Introduction: High blood pressure is a public health problem in Guinea as well as everywhere in Africa. The objective of our study was to assess the epidemiological, clinical and therapeutic aspects of High blood pressure in the general medicine department of the Nzérékoré regional hospital. Methodology:This was a prospective study of a descriptive type, lasting 06 months, from July 1 to December 31, 2014. Results: We recorded 156 cases of High blood pressure among a total of 570 patients, for a hospital frequency of 27%. The 56 - 65 age group was the most affected, at 29.4%, with a predominance of men (sex ratio: 1.5). Alcoholism was the most common cardiovascular risk factor with a frequency of 51.2%, smoking and physical inactivity were found in 35.8% and 30.7% respectively;psychosocial stress was found in 24.3% of patients. The clinic was dominated by headache (100%) and dizziness (57.6%). All our patients were subjected to a healthy diet. Fixed dual therapy was the most widely used treatment regimen, i.e. 91 patients (58.3%) and included a diuretic in 37.1% of cases, a calcium channel blocker in 25% of cases and an ACE inhibitor in 24.3%. Conclusion: This study revealed a high frequency of hypertension in the general medicine department of the regional hospital of N’zérékoré.

关键词： Epidemiology Clinical Therapeutic Hypertension

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Inter Atrial Communication in Adults: About 5 Cases in Guinea

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World Journal of Cardiovascular Diseases 2019年第11期9卷 820-824页

作者： barry ibrahima sory Baldé El Hadj Yaya Camara Abdoulaye Samoura Aly Koivogui Diarra Koivogui Kokoulo Baldé Mamadou Dadhi Condé Mamady Cardiac Service Ignace Deen CHU Conakry Republic of Guinea

Inter auricular communication (AIC) is the most common congenital heart disease after aortic bicuspid disease with an incidence of 5%?-?10% in children and 30%?-?40% in adults. It represents 6% to 10% of congenital heart defects with septal defect. Inter auricular communications (AIC) are the most common cardiac malformations in adults. This was a retrospective study of 5 cases of inter-auricular communication discovered in adulthood in the cardiology department of the Ignace Deen National Hospital between 01 November 2018 and 31 May 2019. The diagnosis was made by the Cardiac Doppler ultrasound. During the study period,?5 cases of AIC were registered at the cardiac department Ignace Deen. The average age of our patients was 51.8 years with extremes of 20 and 70 years. This average age is comparable to that of the literature that reports most develop symptoms after 40 years. In this study, male dominance was noted with 60% versus 40% of female cases. The evolution was marked by a death case of 20% who had AIC associated with an?inter ventricularcommunication (CIV) with signs of global heart failure and four cases had a favorable evolution or 80%.

关键词： CIA Adult Guinea

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Face of the Myocardial Infarction and Diabetes: Epidemiological and Clinical Aspects in the Cardiology Department of the University Hospital Ignace Deen about 46 Cases

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World Journal of Cardiovascular Diseases 2019年第9期9卷 692-697页

作者： Samoura Aly Samoura Sana Camara Abdoulaye barry ibrahima sory Soumaoro Morlaye Koivogui Diarra Doumbouya Mohamed Toure Demba Balde Elhadj Yaya Beavogui Mariama Balde Mamadou Dadhi Conde Mamady Cardiac Service Ignace Deen CHU Conakry Guinea Pneumology Service Ignace Deen CHU Conakry Guinea

The purpose of this study was to describe myocardial infarction in diabetics at the Cardiology Department Ignace Deen. Introduction: New international recommendations defined myocardial infarction, any coronary syndrome accompanied by a modification of cardiac troponin even minimal Tc or Ic [1]. Then for diabetes is defined by the World Health Organization (WHO) a blood glucose greater than 1.10 g/l and/or capillary blood glucose greater than 2.26 g/l after eight hours of fasting [2].?Patients and Methods: Were eligible for both male and female patients at any age admitted to cardiology for myocardial infarction and receiving an ECG echocardiogram;A biological evaluation including blood glucose and troponin Tc or Ic. Discussion: The risk of myocardial infarction is clearly increased in diabetics and is a determinant of coronary heart disease severity and a potential test for other cardiovascular risk factors at the Ignatius Deen Cardiac Department with a frequency of 16.08%. Our result is lower than that of DIOUMM et al. in the Fanh cardiology department of Dakar, Senegal [6], which should reduce the frequency of 22.3%. The high frequency of this pathology in the study DIOUMM is related to the size of their sample on the one hand and secondly the duration of the study, the service capacity on the other hand that could be explained. Conclusion: Diabetes mellitus is a scary medium and long-term disease that causes complications. In addition to infectious and metabolic complications, heart and coronary heart attacks are becoming more common. The tare is dominated by atherosclerosis, which must be prevented through the analysis of diabetic responsibility, with cardiovascular control of risk factors and monitoring of myocardial ischemia, and good cooperation between diabetes specialists, cardiologists and patients.

关键词： Diabetic Myocardial Infarction University Hospital Ignace Deen

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Takayasu Disease Revealed by Arterial Hypertension in a 47-Year-Old Man

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World Journal of Cardiovascular Diseases 2023年第7期13卷 341-348页

作者： Bah Mamadou Bassirou Baldé Thierno Hamidou Wann Thierno Amadou Baldé Elhadj Yaya Baldé Aissatou Tiguidanké Koné Alpha Doumbouya Amadou Diouldé Diallo Hafsatou barry ibrahima sory Samoura Sana Diakité Souleymane Béavogui Mariam Baldé Mamadou Dadhi Cardiology Department Ignace Deen Hospital Conakry Guinea Department of Imaging Ignace Deen Hospital Conakry Guinea Department of Internal Medicine Donka Hospital Conakry Guinea Cardiology Department Donka Hospital Conakry Guinea

Takayasu disease is a chronic vasculitis of the large vessels. It is rare in sub- Saharan Africa and probably under-diagnosed. Arterial hypertension (AH) is a frequent finding. We report the case of a 46-year-old man with Takayasu disease revealed by hypertension. The American College of Rheumatology (ACR) criteria were used for diagnosis, with 4 out of 6 criteria. Echodoppler and angioscanner showed signs of left subclavian stenosis and circumferential, regular arterial thickening. He had a biological inflammatory syndrome. He was treated with prednisone and amlodipine. After 6 months of follow-up, he was diagnosed with tuberculosis and put on anti-tuberculosis treatment.

关键词： Takayasu Disease Hypertension Man

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Cardio-Renal Syndrome: Epidemiological, Clinical, Paraclinical, Etiological Aspects and Prognostic Factors in the Cardiology Department of the CHU Ignace Deen in Conakry

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World Journal of Cardiovascular Diseases 2023年第4期13卷 189-197页

作者： barry ibrahima sory Diakité Foussény Fofana Fatoumata Baldé El Hadj Yaya Bah Mamadou Bassirou Mariama Béavogui Mariam Soumaoro Morlaye Camara Abdoulaye Samoura Aly Koïvogui Diarra Koïvogui Kokoulo Diallo Salématou Baldé Mamadou Dadhi Cardiology Department CHU Ignace Deen Conakry Guinea CHU Donka National Hemodialysis Center Conakry Guinea

Introduction: Heart and kidney diseases are common among patients admitted to hospital and they coexist in a significant number of cases. The interactions between the cardiovascular system and the kidney have been known and described for many years and have led to the description of cardio-renal syndrome. The objective of this study was to determine the frequency;to describe the clinical, etiological and prognostic aspects of acute renal failure in patients hospitalized for chronic congestive heart failure. Method: This was a descriptive retrospective study from January 2, 2018 to December 31, 2022. Included in this study were all the complete records of patients hospitalized for chronic congestive heart failure with serum creatinine ≥120 μmol/I. We’re not included in this study, incomplete files, records of patients hospitalized for other pathologies, records of patients hospitalized for chronic congestive heart failure with normal renal function. Our study variables were qualitative and quantitative divided into clinical, paraclinical and prognostic data. Our data were analyzed using the EPI-info 7.***.2.6 software. Data entry and presentation were carried out using Word, Excel and PowerPoint from the 2016 Office Pack. Results: We collected 830 files of which 114 met our selection criteria, a frequency of 13.73%. The mean age of the patients was 47 ± 19 years. The F/M sex ratio was 1.23. The dominant etiologies were hypertension followed by diabetes with respectively 60.5% and 23.7%. Toxic factors including tobacco accounted for 7.9% of cases. Dyspnea accounted for 86.8%. Most of our patients were grade 3 or 36% based on systolic blood pressure on admission with an average of 164.16 ± 33.95 mmHg and an average diastolic blood pressure of 93.24 ± 20.40 mmHg. Biologically, the serum creatinine revealed a high frequency of 201 - 400 μmol/l (33% of cases) with an average value of 586.49 ± 631.44 μmol/l with the extremes 2.960 and 2448.68 μmol/I. Anemia was moderate in 3

关键词： Cardio-Renal Syndrome Ignace Deen

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Right Atrium Myxoma in an 11-Year-Old Girl in Guinea

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World Journal of Cardiovascular Diseases 2020年第7期10卷 432-436页

作者： barry ibrahima sory Balde El Hadj Yaya Camara Abdoulaye Koivogui Kokoulo Samoura Aly Koivogui Diarra Soumaoro Morlaye Toure Demba Camara Aboubacar Bah Mamadou Bassirou Sylla Fatou Beavogui Mariame Balde Mamadou Dadhi Conde Mamady Department of Cardiology at Ignace Deen National Hospital CHU Conakry Republic of Guinea Pneumology department of the Ignace Deen National Hospital CHU Conakry Republic of Guinea

The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl. It was an 11-year-old girl weighing 22 kg, admitted for exertional dyspnea, dry cough, palpitations, hepatitis, abdominal bloating, fever evolving for more than 9 months without a history of known cardiovascular disease;referral from a pulmonology department for cardiomegaly and right pleurisy. At cardiac auscultation, the rhythm was irregularly fast at 130 beats without added noise with a blood pressure of 110/65 mmhg. In the lungs, there was silence and a decrease in vocal vibrations at the right base, SaO2 at 70%. Elsewhere a thoracic collateral venous circulation was visible. Electrocardiogram recorded rapid atrial fibrillation at 134 cycles. The cardiac ultrasound concluded that there was a mobile mass in the right atrium prolapsing in the right ventricle measuring 25 mm × 18.9 mm suggesting a myxoma. The myxoma of the right atrium is of a rare localization with a polymorphic clinical manifestation. It should be diagnosed as early as possible to avoid the occurrence of dreaded complications. Its management is surgical.

关键词： Myxoma Right Atrium 11-Year-Old Girl Guinea

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