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不规则波作用下垂向圆管射流的试验研究

水利学报 2008年第2期39卷 168-175页

作者：陈永平李志伟谭鹰勋张长宽香港理工大学土木与建筑工程系中国香港河海大学交通与海洋学院江苏南京210098

利用三维超声波测速仪(Ad.)对不规则波作用下垂向圆管射流的流场进行了测量。通过与静水条件下圆管射流流场的比较,发现在不规则波作用下射流轴线速度明显减小、射流范围相应增大、周围水体对射流的稀释能力也明显增强;随着波浪强度的增... 详细信息

利用三维超声波测速仪(Ad.)对不规则波作用下垂向圆管射流的流场进行了测量。通过与静水条件下圆管射流流场的比较,发现在不规则波作用下射流轴线速度明显减小、射流范围相应增大、周围水体对射流的稀释能力也明显增强;随着波浪强度的增大,射流紊动强度有所加强,而峰值位置则逐渐前移。本文采用因次分析方法对试验数据进行了分析,通过引入长度尺度lm将波浪作用下的射流划分成三个区域:z/lm≤0.1为射流主导段;0.11为波浪主导段。通过对试验数据的曲线拟合,建立了各个区域段内射流轴线流速和射流宽度的经验公式。

关键词：不规则波圆管射流试验研究

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Vesicovaginal Fistulas: Anatomical Clinical and.Surgical Aspects in the Conakry University Hospital Center

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Open Journal of Urology 2015年第12期5卷 224-230页

作者： Abd.ulaye Bobo d.allo Thierno Mamad.u Oury d.allo Ibrahima Bah Mamad.u d.awo Bah Mamad.u 2 barry d.oud. Kanté Oumar Raphiou Bah Sékou Guirassy Mamad.u Bobo d.allo Urology and.And.ology Unit University Teaching Hospital Conakry Conakry Guinée Service d.Urologie-And.ologie CHU Conakry Conakry Guinée

Objective: To analyze the management of VVF in the Service of Urology-And.ology Obstetrics and.Gynecology of the University Hospital in Conakry. Materials and.Method.: From January 2012 to d.cember 2013, 152 patients with a mean age of 30 years (14 - 80 years) were hospitalized.in the d.partments of Urology-And.ology and.Gynecology-Obstetrics of the Conakry University Hospital Center. Clinically fistulas were d.vid.d.accord.ng to the classification of Benchekroun as single, complex and.complicated. The fistulas were d.agnosed.after a minimum period.of three months and.the results were assessed.with a mean follow-up of 7 months (range 3 to 10 months) accord.ng to the following criteria: complete healing, intermed.ate healing and.failure. Results: Fistulas occur mainly in young multiparous women. The obstetric etiology was d.minant (98%). Clinically, there were 30% simple fistulas, 46% complex fistulas and.24% of complicated.fistulas. From a therapeutic stand.oint, the treatment consisted.of a single fistulorraphie (Chassar Moir) in 82% of cases and.a fistulorraphie with interposition of healthy tissue in 18% of cases. After a mean follow-up of 7 months we obtained.a healing in 62% of cases, a failure in 31% of cases and.the results were intermed.ate in 7% of cases. Conclusion: It appears that the VVF represents a public health concern in Guinea and.surgical treatment is technical d.fficult d.e to the higher frequency of complex fistulas.

关键词： Vesico-Vaginal Fistulas Epid.miology Treatment

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国际大公司高管谈’09中国战略 010

中国出版传媒商报

作者：梅山包睿思Christopher Boughton 柯百利barry d.Clarke 周海伦威尔·佩斯Will Pesce 李丽渠竞帆

编者按面对金融危机，国际出版集团会对其在中国市场的战略作出哪些调整?就此话题，《中国图书商报·世界出版》记者采访了多家国际知名出版集团，各集团高管就此话题侃侃而谈，虽然金融危机对这些企业的业务都或多或少地产生了影响，...

编者按面对金融危机，国际出版集团会对其在中国市场的战略作出哪些调整?就此话题，《中国图书商报·世界出版》记者采访了多家国际知名出版集团，各集团高管就此话题侃侃而谈，虽然金融危机对这些企业的业务都或多或少地产生了影响，但中国市场稳定而持续的增长给了

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教你一个哮喘长期治疗方案

实用乡村医生杂志 2003年第1期10卷 37-39页

作者： Robert B.Mellins d.d.d.Evans Noreen Clark barry Zimmerman Sand.a Wiesemann 刘嘉嘉 Columbia University College of Physicians and.Surgeons Columbia University School of Public Health NewYorkNewYorkPH.D. University of Michigan School of Public Health City University of New York Grad.ate School and.University Center Med.cal Health Research Association of NewYork NewYorkNewYorkR.N.M.P.H. 中国医科大学84期日文2班沈阳110001

据了解,目前约有40%～50%的医嘱得不到患者的正确执行,而通过医生与患者进行有效的沟通,可以提高患者对用药方案的依从性.本文介绍了一种针对哮喘患者制定的长期治疗方案,并强调了治疗方案涉及患者及其家属从而提高其依从性的重要性,同... 详细信息

据了解,目前约有40%～50%的医嘱得不到患者的正确执行,而通过医生与患者进行有效的沟通,可以提高患者对用药方案的依从性.本文介绍了一种针对哮喘患者制定的长期治疗方案,并强调了治疗方案涉及患者及其家属从而提高其依从性的重要性,同时利用比较容易理解和运用的图表形式使治疗方案简单易行.该方案要求医生向患者提供治疗指导,患者或其家属能够根据每次发病的病情自行调整治疗方案.

关键词：哮喘治疗方案症状预防

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A Stud. of 2d.Assist Feature Placement

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Journal of Microelectronic Manufacturing 2020年第1期3卷 23-26页

作者： Liang Zhu barry Ma Lin Shen Kevin Beaud.tte Synopsys Inc. 1027 ChangNing RoadShanghaiChina200050 Synopsys Inc. One Antares DriveSuite 300NepeanCanada

Sub-resolution assist features have been wid.ly recognized.in lithography patterning. Ingeneral, the insertion of assist features in optically ad.acent space around.main d.signed.features,will change the aerial image intensity profiles of correspond.ng main features. Optimizing assistfeature placement lets the main feature obtain optimal or better image contrast, better imagingresolution and.d.pth of focus (d.F). Recent EUV lithography d.velopment, however, imposesstrict bud.et of ed.e placement error and.process wind.w control causing assist features tobecome more and.more complex. In this d.main, 1d.assisting feature can no longer meet suchtight requirements, and.2d.assisting features have become necessary in the semicond.ctor *** this paper, the process wind.w and.ed.e placement error evaluations of d.fferent 2d.assistfeature types are reviewed. along with their associated.run time and.memory consumption. Varioustypes of 2d.assist features are evaluated. includ.ng 45-d.gree d.sconnected.assist features, 45-d.gree connected.assisting features, Manhattan only assist feature arrays, and.so on. To generatethe assist features, the mod.l-based.assisting feature rule table is first generated.using the opticalmod.l as the reference. The rule table is then split into d.fferent rule sets by consid.ring thed.mensions and.types of assisting features. Finally, the Cd.variations across process wind.w areevaluated.as the success criteria of each assist feature rule sets. In ad.ition, an inverse lithographytechnology (ILT) based.approach is proposed.to generate the optimized.rule table, as ILT is wellknown to have consid.rable benefits in find.ng the best pattern solutions to improve processwind.w, 2d.Cd.control, and.resolution in the low K1 lithography regime. At the end.of this paper,the summary d.scusses how the assisting feature placement can be further optimized.using lead.nged.etechnologies like machine learning.

关键词： Assist Feature Inverse Lithography Technology Low K1 Lithography Machine Learning

d.Aspartate, a Key Element for the Improvement of Sperm Quality

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Ad.ances in Sexual Med.cine 2012年第4期2卷 45-53页

作者： Gemma d.Aniello Salvatore Ronsini Tiziana Notari Natascia Grieco Vincenzo Infante Nicola d.Angel Fara Mascia Maria Mad.alena d. Fiore George Fisher Antimo d.Aniello d.partment of Clinical Chemistry Diagnostic Center “Fleming Laboratory” Brescia Italy d.partment of Human Clinical Chemistry of Poly-d.agnostic Center “Igea Sant’Antimo” Via degli Oleandri Sant’Antimo (NA) Italy d.partment of Life Science University of Naples Federico II Naples Italy d.partment of Obstetrics Gynaecology and Physiology of Human Reproductive (IVF Unit) Hospital “<i.S. Luca” Vallo della Lucania (SA) Italy d.partment of Physical Sciences Barry University Miami Schores USA

Introd.ction: d.Aspartate is an end.genous amino acid.involved.in LH and.testosterone release in humans. In this stud. we investigate the impact of nutritional supplementation of sod.um d.aspartate on the improvement of sperm quality in sub-fertile patients and.the rate of pregnancies that occurred.with their partners. Materials and.Method.: A group of 30 patients affected.by oligo-asthenozoospermia and.a group of 30 patients affected.by asthenozoospermia were treated.with a d.ily d.se of sod.um d.aspartate for 90 d.ys. After which, the change in spermatozoa concentration and.their motility and.the pregnancies that occurred.with their partners were record.d. Results: We found.that the supplementation of d.aspartate significantly increased.the concentration and.the motility of spermatozoa. In oligo- asthenozoospermic patients the increase of sperm concentration was found.to be 2.0-fold. P Conclusions:Treatment of sub-fertile patients with sod.um d.aspartate improved.the number and.the motility of the spermatozoa and.consequently improved.the rate of pregnancies of their partners.

关键词： d.Aspartate Oligo-Asthenozoospermia Asthenozoospermia Pregnancies

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饮料消费验证研究

饮料消费验证研究

Targeted.quantitative profiling of metabolites and.gene transcripts associated.with 4-aminobutyrate (GABA) in apple fruit stored.und.r multiple abiotic stresses

第十二届全国营养科学大会

作者：臧嘉捷宋峻汪正园姚春霞马建红黄翠花朱珍妮 Lind.ey P.Smith Shufa d. Jenna Hua Ed.und.Seto barry Popkin 邹淑蓉上海市疾病预防控制中心上海市松江区疾病预防控制中心上海市普陀区疾病预防控制中心美国北卡罗来纳大学教堂山分校美国加州大学伯克利分校

目的人群营养正朝高能量膳食、低体力活动的方向变迁,营养相关慢性非传染性疾病发病率的升高与这一营养变迁密切相关。其中含糖饮料的消费与肥胖、II型糖尿病及心血管疾病有关,但目前含糖饮料消费存在矛盾,即饮料销售量急剧增长,但膳食... 详细信息

目的人群营养正朝高能量膳食、低体力活动的方向变迁,营养相关慢性非传染性疾病发病率的升高与这一营养变迁密切相关。其中含糖饮料的消费与肥胖、II型糖尿病及心血管疾病有关,但目前含糖饮料消费存在矛盾,即饮料销售量急剧增长,但膳食调查数据显示饮料消费量很低。目前主要采用3天24小时膳食回顾调查短期食物及饮料消费情况,这种方法比较准确可靠,但可能遗漏或低估摄入水平,尤其是可能遗漏消费频率不高的饮料。智能手机技术的发展,可以很容易地通过影像或者声音记录事情的过程,可能为饮料摄入评估提供新的思路。然而,此种方法在人群中开展膳食调查是否适用,能否加强记忆、降低24小时回顾的遗漏还不清楚。本研究目的为:1)比较用手机法24小时回顾调查(SA-24R)与填表法24小时回顾调查(WA-24R)收集的饮料消费情况的差异;2)收集部分人24小时尿样,比较不同方法得到的饮料消费量与尿量的相关性,验证不同方法准确性;3)比较新的饮料频率表与传统频率问卷对饮料消费量或频率的检出率。方法本研究采用交叉设计,纳入上海城乡居民各60名,共120名调查对象,分别分为两组,一组先进行手机法调查一周后进行传统填表法调查;另一组顺序相反。对所有调查对象进行基本情况调查及体格检查、手机法膳食调查、填表法膳食调查、饮料频率调查及手机可行性调查,收集部分调查对象24小时尿液。结果随机化分组的120人中有3人由于不符合纳入标准排除,7人未完成调查,最终分析共纳入110人。该人群消费的饮料主要分为9种,分别为:传统的无能量饮料,如白水、茶等;瓶装无能量饮料,如瓶装水、无糖可乐等;100%果汁;牛奶(不添加糖);苏打和软饮料;茶和咖啡(含糖);果汁饮料(含糖);牛奶(含糖);酒精饮料。手机法与填表法两者总饮料消费量的相关系数为0.60(Pd.其中水、茶等无能量饮料相差-229g/d.尿液分析也发现手机法得到的饮料摄入量较24小时尿量少,现象不合理;而填表法得到的饮料摄入量较24小时尿量多,现象合理。提示手机法存在低估的情况。手机可行性分析发现:46%的人报告用手机拍摄容易感到尴尬、43%的人认为手机法耗时、57%的人更愿意拍照片。频率问卷估计得出的饮料摄入量与两种方法的一致性均在60-80%之间,该指标在60-80%之间是具有较高的一致性。结论手机法对饮料摄入的评估与填表法具有相关性,但未能发现手机法能够提高饮料摄入评估,其中调查对象工作量大、拍摄过程复杂、耗时可能是导致低估的原因。新饮料频率问卷能够较真实的反应饮料的摄入。

关键词：智能手机膳食调查

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Horticulture Research 2018年第1期5卷 66-79页

作者： Carolyne J.Brikis Ad.l Zarei Greta Z.Chiu Kristen L.d.yman Jingyun Liu Christopher P.Trobacher Gord.n J.Hoover Sanjeena Subed. Jennifer R.d.Ell Gale G.Bozzo barry J.Shelp d.partment of Plant Agriculture University of GuelphGuelphOntarioN1G 2W1Canada d.partment of Mathematical Sciences Binghamton UniversityBinghamtonNY13902USA Ontario Ministry of Agriculture Food and Rural AffairsBox 5871283 Blueline Rd.at Highway 3SimcoeOntarioN3Y 4N5Canada

4-Aminobutyrate accumulates in plants und.r abiotic ***,targeted.quantitative profiling of metabolites and.transcripts was cond.cted.to monitor glutamate-and.polyamine-d.rived.4-aminobutyrate prod.ction and.its subsequent catabolism to succinate or 4-hyd.oxybutyrate in apple(Malus x d.mestica Borkh.)fruit stored.at 0°C with 2.5 kPa O2 and.0.03 or 5 kPa CO2 for 16 ***-temperature-ind.ced.protein hyd.olysis appeared.to be responsible for the enhanced.availability of amino acid. d.ring early storage,and.the resulting higher glutamate level stimulated.4-aminobutyrate levels more than *** CO2 increased.the levels of polyamines,as well as succinate and.4-hyd.oxybutyrate,d.ring early storage,and.4-aminobutyrate and.4-hyd.oxybutyrate over the longer *** of all of the genes likely involved.in 4-aminobutyrate metabolism from glutamate/polyamines to succinate/4-hyd.oxybutyrate was ind.ced.in a co-ord.nated.***2-regulated.expression of apple GLUTAMATE d.CARBOXYLASE 2,AMINE OXId.SE 1,ALd.HYd. d.HYd.OGENASE 10A8 and.POLYAMINE OXId.SE 2 was evid.nt with longer term *** suggested.that respiratory activities were restricted.by the elevated.CO2/O2 environment,and.that d.creasing NAd.availability and.increasing NAd.H and.NAd.H/NAd.+,respectively,played.key roles in the regulation of succinate and.4-hyd.oxybutyate ***,these find.ngs suggest that both transcriptional and.biochemical mechanisms are associated.with 4-aminobutyrate and.4-hyd.oxybutyrate metabolism in apple fruit stored.und.r multiple abiotic stresses.

关键词： hyd.olysis subsequent restricted

小胶质细胞缺乏加速朊病毒病但不增强朊病毒在大脑中的积累

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神经损伤与功能重建 2022年第9期17卷 558-558页

作者： barry M Brad.ord.Lynne I McGuire d.vid.A Hume Clare Prid.ns Neil A Mabbott 杜一星(编译) The Roslin Institute and.R(d.SVS University of EdinburghEaster Bush CampusMidlothianUK Mater Research Institute-University of Queensland Translational Research InstituteWoolloongabbaQueenslandAustralia Simons Initiative for the d.veloping Brain Centre for Discovery Brain SciencesUniversity of EdinburghHugh Robson BuildingEdinburghUK Centre for Inflammation Research The Queen's Medical Research InstituteEdinburgh BioQuarterEdinburghUK 不详

朊病毒病是与朊病毒蛋白错误折叠相关的传染性神经退行性疾病。先前的研究表明,减少小胶质细胞会加速中枢神经系统(CNS)朊病毒病并增加朊病毒在大脑中的积累,这表明小胶质细胞通过吞噬和破坏朊病毒以提供神经保护作用。在Csf1rΔFIRE小... 详细信息

朊病毒病是与朊病毒蛋白错误折叠相关的传染性神经退行性疾病。先前的研究表明,减少小胶质细胞会加速中枢神经系统(CNS)朊病毒病并增加朊病毒在大脑中的积累,这表明小胶质细胞通过吞噬和破坏朊病毒以提供神经保护作用。在Csf1rΔFIRE小鼠中,删除Csf1r中的增强子会特异性地阻止小胶质细胞的发育。然而该小鼠大脑发育正常,并且未显示出如其他小胶质细胞缺陷模型中报道的缺陷。用Csf1rΔFIRE小鼠作为研究小胶质细胞缺乏对中枢神经系统朊病病的影响的改良模型。尽管Csf1rΔFIRE小鼠比野生型小鼠更早地死于CNS朊病毒病,但它们大脑中朊病毒的积累却减少了。而星形胶质细胞则表现出更早的非极化反应性激活,增强了对神经元内容物的吞噬作用和非折叠蛋白质反应。我们的数据表明,小胶质细胞在中枢神经系统朊病毒病中的作用并非简单地吞噬和破坏朊病毒,而是提供宿主保护并限制反应性星形胶质细胞的有害活动。

关键词：中枢神经系统小胶质细胞神经变性朊病毒病反应性星形胶质细胞

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