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海洋石油 1988年第2期 20-23页

作者： Eric j.barron 张龙渔

已有一些关于全球白垩纪古地理实例的报导(Termier,1952;B(?)rron 等,1981;Zie-gler 等,1982)。这次国际际协调计划191号项目的主要目的是利用最新的板块重建和白垩纪滨线位置的资料编制白垩纪的每一个阶的全球综合性古地理基础图。编... 详细信息

已有一些关于全球白垩纪古地理实例的报导(Termier,1952;B(?)rron 等,1981;Zie-gler 等,1982)。这次国际际协调计划191号项目的主要目的是利用最新的板块重建和白垩纪滨线位置的资料编制白垩纪的每一个阶的全球综合性古地理基础图。编制这一基础图的目

关键词：古地理图协调计划自然地理图滨线地质

太平洋地区新第三纪事件的时代、性质和相互关系

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宝石和宝石学杂志(中英文) 1989年第3期 16-16页

作者： j.A.barron 吴益宏

国际地质对比计划246项目研究的主要内容为,整个太平洋和东印度洋地区新第三纪地层中可辨认的主要气候,构造、演化事件和化石组合的识别、特征以及时代.十月份,在由该计划领导人,日本静岗大学的***组织的一次会议上,述评了该项目的最新... 详细信息

国际地质对比计划246项目研究的主要内容为,整个太平洋和东印度洋地区新第三纪地层中可辨认的主要气候,构造、演化事件和化石组合的识别、特征以及时代.十月份,在由该计划领导人,日本静岗大学的***组织的一次会议上,述评了该项目的最新进展,这次会议由日本科学促进会和藤原科学基金会赞助。这次会议讨论四类主要的事件:大约16Ma前新第三纪中期的气候适宜期;大约15—13Ma、6—7Ma和2.5Ma前的新第三纪中大的气温升降事件:大约15Ma前日本海的张开和有关的太平洋构造事件;发

关键词：北太平洋新第三纪气候晚第三纪国际地质对比计划依豆半岛伊豆半岛

红细胞输注与儿童重症监护病房院内感染的相关性研究

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中国小儿急救医学 2010年第4期 291-291页

作者： White M barron j Gombein j 杨明首都医科大学附属北京儿童医院

目的成人研究发现输红细胞与院内感染相关。本研究旨在探讨输红细胞是否同样与儿童重症监护病房(PICU)院内感染相关,淋巴细胞计数减少是否为可能的机制之一。设计历史性对列研究。场所单中心,一所大学附属儿童医院含内外科的综合性PIC... 详细信息

目的成人研究发现输红细胞与院内感染相关。本研究旨在探讨输红细胞是否同样与儿童重症监护病房(PICU)院内感染相关,淋巴细胞计数减少是否为可能的机制之一。设计历史性对列研究。场所单中心,一所大学附属儿童医院含内外科的综合性PICU。对象 2005年1月1日至7月3日PICU收住的18岁以下患儿。干预无。测量指标和主要结果院内感染(呼吸系统感染、尿路感染和血流感染)为主要观察指标,输红细胞后14 d内发生者被认为是输血后感染。在209例纳入研究的患儿中,32例(15%)发生院内感染,45例(22%)输过红细胞。发生院内感染的患儿输红细胞的比率显著高于无院内感染者(OR 18.0,95%CI 7.6～45.9,P<0.001)。经剂量依赖性分析发现,输红细胞≥3次的患儿院内感染发生率与输1～2次红细胞者相当(61%vs 44%,P=0.365),但前者病死率更高(22%vs 0,P=0.04)。多元Logistic回归分析在控制了性别、年龄、PICU住院时间、侵入性导管操作、机械通气和手术等因素的影响后,发现输红细胞仍与院内感染风险相关(OR 3.73,95%CI 1.19～11.85,P=0.023)。输血患儿淋巴细胞绝对数较未输血者低(1 605/μl vs 2 054/μl,P=0.041),但白细胞总数相当(10.4×10~3/μl vs 11.4×10~3/μl,P=0.52)。结论 PICU输红细胞的患儿发生院内感染的风险增加。

关键词：红细胞输注细菌感染儿童重症监护病房淋巴细胞计数回顾性研究疾病严重程度指数

Particle image velocimetry evaluation of flow-altering countermeasures for local scour around a submerged circular cylinder

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International journal of Sediment Research 2022年第4期37卷 411-423页

作者： Priscilla Williams Ram Balachandar Vesselina Roussinova Ronald barron Department of Civil and Environmental Engineering University of Windsor Department of Mechanical Automotive and Materials EngineeringUniversity of Windsor Department of Mathematics and Statistics University of Windsor

The effect of scour countermeasures on the mechanism of local scour around a cylinder requires clarification in order to develop design methodology for use in practice. Previous investigations on countermeasure performance, though useful, have not provided adequate measurements to support this understanding. In the present investigation, particle image velocimetry(PIV) measurements were acquired at several streamwise-vertical planes in the flow field surrounding a submerged circular cylinder with a vertical splitter plate and with a rectangular collar(a horizontal base plate). Analysis of the distribution of mean streamwise velocity and Reynolds shear stress as well as the scour formation indicated that the splitter plate disrupted shear layer interaction in the wake region, reducing the width of scour downstream of the cylinder by 3%. The collar eliminated scour upstream of the cylinder entirely by providing protection at the sides of the cylinder where the shear stress exceeds the critical bed shear stress, and the streamwise velocity distribution in the region between the cylinder and the channel sidewall indicated that installation of a rectangular collar causes flow separation at a point further upstream on the cylinder surface.

关键词： Scour and erosion Local scour Pier scour Scour countermeasures Hydraulic modelling Particle image velocimetry (PIV)

Superchiral near fields detect virus structure

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Light(Science & Applications) 2020年第1期9卷 103-112页

作者： Tarun Kakkar Chantal Keijzer Marion Rodier Tatyana Bukharova Michael Taliansky Andrew j.Love joel j.Milner Affar S.Karimullah Laurence D.barron Nikolaj Gadegaard Adrian j.Lapthorn Malcolm Kadodwala School of Chemistry Joseph Black BuildingUniversity of GlasgowGlasgow G128QQUK Institute of Molecular Cell and Systems Biology and School of Life SciencesUniversity of GlasgowG128QQ GlasgowUK james Hutton Inst Cell&Mol SciDundee DD25DAUK Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS Moscow 117997Russia School of Engineering Rankine BuildingUniversity of GlasgowGlasgow G128LTUK

Optical spectroscopy can be used to quickly characterise the structural properties of individual ***,it cannot be applied to biological assemblies because light is generally blind to the spatial distribution of the component *** insensitivity arises from the mismatch in length scales between the assemblies(a few tens of nm)and the wavelength of light required to excite chromophores(≥150 nm).Consequently,with conventional spectroscopy,ordered assemblies,such as the icosahedral capsids of viruses,appear to be indistinguishable isotropic spherical *** limits potential routes to rapid high-throughput portable detection appropriate for point-of-care ***,we demonstrate that chiral electromagnetic(EM)near fields,which have both enhanced chiral asymmetry(referred to as superchirality)and subwavelength spatial localisation(∼10 nm),can detect the icosahedral structure of virus ***,they can detect both the presence and relative orientation of a bound virus *** illustrate the potential uses of the exquisite structural sensitivity of subwavelength superchiral fields,we have used them to successfully detect virus particles in the complex milieu of blood serum.

关键词： chiral detect fields

Multiple myeloma survival in New South Wales, Australia, by treatment era to 2020

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Cancer Biology & Medicine 2024年第8期21卷 703-711页

作者： Eleonora Feletto Qingwei Luo Anna Kelly Marianne Weber David Goldsbury Katherine barron Karen Canfell Xue Qin Yu The Daffodil Centre The University of SydneyA Joint Venture with Cancer Council NSWSydney NSW 2006Australia

Objective: Australia has relatively high multiple myeloma(MM) incidence and mortality rates. Advancements in MM treatment over recent decades have driven improvements in MM survival in high-income countries;however, reporting in Australia is limited. We investigated temporal trends in population-wide MM survival across 3 periods of treatment advancements in New South Wales(NSW), ***: Individuals with an MM diagnosis in the NSW Cancer Registry between 1985 and 2015 with vital follow-up to 2020, were categorized into 3 previously defined treatment eras according to their diagnosis date(1985±1995, chemotherapy only;1996±2007, autologous stem cell transplantation;and 2008±2015, novel agents including proteasome inhibitors and immunomodulatory drugs). Both relative survival and cause-specific survival according to Fine and Gray's competing risks cumulative incidence function were calculated by treatment era and age at ***: Overall, 11,591 individuals were included in the study, with a median age of 70 years at diagnosis. Five-year relative survival improved over the 36-year(1985±2020) study period(31.0% in 1985±1995;41.9% in 1996±2007;and 56.1% in 2008±2015). For individuals diagnosed before 70 years of age, the 5-year relative survival nearly doubled, from 36.5% in 1985±1995 to 68.5% in 2008±2015. Improvements for those > 70 years of age were less pronounced between 1985±1995 and 1996±2007;however, significant improvements were observed for those diagnosed in 2008±2015. Similar overall and age-specific patterns were observed for causespecific survival. After adjustment for gender and age at diagnosis, treatment era was strongly associated with both relative and cause-specific survival(P < 0.0001).Conclusions: Survival of individuals with MM is improving in Australia with treatment advances. However, older age groups continue to experience poor survival outcomes with only modest improvements over time. Given the increasing prevalence of MM in

关键词： Multiple myeloma cancer epidemiology survival analysis competing risk analysis Australia

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Radiofrequency electric-field heating behaviors of highly enriched semiconducting and metallic single-walled carbon nanotubes

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Nano Research 2015年第9期8卷 2859-2870页

作者： Stuart j. Corr Mustafa Raoof Brandon T. Cisneros Alvin W. Orbaek Matthew A. Cheney justin j. Law Nadia C. Lara Andrew R. barron Lon j. Wilsor Steven A. Curley Division of Surgery Baylor College of Medicine Houston TX 77030 USA Department of Surgical Oncology University of Texas M.D. Anderson Cancer Center Houston TX 77030 USA Department of Chemistry and the Richard E. Smalley Institute for Nanoscale Science and Technology Rice University Houston TX 77005 USA Department of Surgery The University of Arizona College of Medicine Tucson AZ 85724 USA Department of Chemistry and Biochemistry University of California San Diego La Jolla CA 92093 USA College of Engineering Swansea University Singleton Park Swansea SA2 8PP Wales UK Department of Mechanical Engineering and Materials Science Rice University Houston TX 77005 USA

It is theorized that enhanced thermal heating may result from exposing single-walled carbon nanotubes （SWNTs） embedded in a conductive host to radiofrequency （RF） electric fields. We examine the RF-induced （13.56 MHz） heating behaviors of 95% metallic- and semiconducting-enriched SWNTs （m-/s-SWNTs） suspended in aqueous solutions with varying NaC1 molarity （0.001 mM-1 M）. The heating effects were only evident for host molarities below 1 mM （equivalent to 0.1 S/m） at which the s-SWNT heating rates dominated those of the m-SWNTs. The heating effects were localized to aligned and aggregated ＂SWNT ropes＂ -1 cm in length that formed in suspension, parallel to the electric-field vector, during the RF exposure. For molarities above 1 mM, no enhancements were evident, owing to the large heating effects of the bulk ionic NaC1 suspensions, which were observed in previous studies. Although larger enhancement effects proportional to the host conductivity have been theoretically predicted for m-/s-SWNT suspensions, this was not observed most likely because of the aggregation and screening effects, which diminished the scattered electric field near the m-/s-SWNTs. Our research may further the development of better nanoparticle heating agents for applications such as non-invasive RF-induced cancer hyperthermia.

关键词： rad.iofrequency,carbon nanotubes,metallic,semiconducting,hyperthermia

Solvent-free microwave-assisted synthesis of tenorite nanoparticle-decorated multi-walled carbon nanotubes

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journal of Materials Science & Technology 2019年第6期35卷 1121-1127页

作者： jennifer A. Rudd Cathren E. Gowenlock Virginia Gomez Ewa Kazimierska Abdullah M. Al-Enizi Enrico Andreoli Andrew R. barron Energy Safety Research Institute Swansea University Bay Campus Swansea SA1 8EN UK Chemistry Department College of Sciences KingSaud University Riyadh Saudi Arabia Department of Chemistry Rice University Houston Texas 77005 USA Department of Materials Science and Nanoengineering Rice University Houston Texas 77005 USA

Copper-decorated carbon nanotubes(CNTs) have important applications as precursors for ultraconductive copper wires. Tenorite-decorated CNTs(CuO-CNTs) are ideal candidates and are currently developed using laborious processes. For this reason, we have developed a facile and scalable method for the synthesis of CuO-CNTs from copper acetate. It was found that the optimal loading of copper acetate onto the CNTs was 23.1 wt% and that three 1-minute microwave treatments were sufficient for the decomposition of copper acetate to copper oxide. The loading of copper oxide onto the nanotubes was confirmed using X-ray photoelectron spectroscopy, energy-dispersive X-ray spectroscopy and thermogravimetric analysis. The materials were characterised using X-ray diffraction and scanning electron microscopy.

关键词： Microwave-assisted synthesis Multi-walled carbon nanotubes Tenorite Nanoparticle

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Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium

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Bone Research 2017年第2期5卷 123-136页

作者： Melissa L barron Mark S Rybchyn Sutharshani Ramesh Rebecca S Mason S Fiona Bonar Paul Stalley Sundeep Khosla Bernie Hudson Christopher Arthur Edward Kim Roderick j Clifton-Bligh Phillip B Clifton-Bligh Department of Physiology School of Medical Sciences Bosch Institute University of Sydney Sydney 2006 New South Wales Australia Douglas HanlyMoir Pathology Macquarie Park 2113 New South Wales Australia Department of Orthopaedics Royal Prince Alfred HospitalCamperdown 2050 New South Wales Australia Department of Endocrinology Mayo Clinic Rochester 55905 MN USA Department of Microbiology Royal North Shore Hospital St Leonards 2065 New South Wales Australia Department ofMicrobiology Royal North Shore Hospital St Leonards 2065 New South Wales Australia Department of Haematology Royal North Shore Hospital St Leonards 2065 New South Wales Australia Department of Endocrinology Royal North Shore Hospital St Leonards 2065 New SouthWales Australia and Faculty of Medicine University of Sydney Sydney 2006 New South Wales Australia

Fibrogenesis imperfecta ossium is a rare disorder of bone usually characterized by marked osteopenia and associated with variable osteoporosis and osteosclerosis, changing over time. Histological examination shows that newly formed collagen is abnormal, lacking birefringence when examined by polarized light. The case presented demonstrates these features and, in addition, a previously undocumented finding of a persistent marked reduction of the serum C3 and C4. Osteoblasts established in culture from a bone biopsy showed abnormal morphology on electron microscopy and increased proliferation when cultured with benzoylbenzoyl-ATP and 1,25-dihydroxyvitamin D, contrasting with findings in normal osteoblasts in culture. A gene microarray study showed marked upregulation of the messenger RNA(mRNA) for G-protein-coupled receptor 128(GPR 128), an orphan receptor of unknown function and also of osteoprotegerin in the patient's osteoblasts in culture. When normal osteoblasts were cultured with the patient's serum, there was marked upregulation of the mRNA for aquaporin 1. A single pathogenetic factor to account for the features of this disorder has not been defined, but the unique findings described here may facilitate more definitive investigation of the abnormal bone cell function.

关键词： ultrastructural cellular Clinical

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