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Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： baoqi hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou Bo Ma Yan Luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan Kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell ***,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development ***,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo *** this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in ***,we used SOX2 and PAX6 immunostaining to identify retinal progenitor *** then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between ***,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,*** timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant *** study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina *** findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

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白内障超声乳化术源性散光影响因素分析

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西安交通大学学报（医学版） 2023年第2期44卷 263-270页

作者：黄瑶瑶胡宝琪王欣龙潭马挺王睿西北大学生命科学学院陕西西安710069 西北大学附属第一医院陕西西安710002 西安市第一医院陕西西安710002 陕西省眼科研究所陕西西安710002 西安交通大学第一附属医院眼科陕西西安710061

目的观察白内障超声乳化术源性散光(surgically induced astigmatism,SIA)的影响因素。方法对2021年12月-2022年3月的69例具有角膜规则散光的白内障患者进行白内障超声乳化手术,术后观测以角膜顶点为中心3 mm、5 mm、7 mm直径范围内的... 详细信息

目的观察白内障超声乳化术源性散光(surgically induced astigmatism,SIA)的影响因素。方法对2021年12月-2022年3月的69例具有角膜规则散光的白内障患者进行白内障超声乳化手术,术后观测以角膜顶点为中心3 mm、5 mm、7 mm直径范围内的角膜前表面、后表面以及角膜前表面的模拟角膜屈率(Sim K)的SIA,使用矢量分析计算XSIA、YSIA和SIA均值(|SIA|),并对SIA与年龄、眼轴长度(axial length,AL)、前房深度(anterior chamber depth,ACD)、角膜直径(white-to-white,WTW)、中央角膜厚度(central corneal thickness,CCT)使用Pearson相关性分析,使用多元线性回归进行SIA影响因素的分析。结果69例患者的平均年龄为(63.25±14.74)岁,其中男性28例(40.58%)。分析发现,Sim K的|SIA|与WTW呈负相关(r=-0.265,P=0.028);3 mm、5 mm、7 mm前表面|SIA|与WTW呈负相关(r=-0.320,P=0.007;r=-0.337,P=0.005;r=-0.287,P=0.017);3 mm、5 mm、7 mm后表面|SIA|与AL呈负相关(r=-0.390,P=0.001;r=-0.352,P=0.003;r=-0.317,P=0.008)。多元回归分析结果显示,WTW与Sim K、3 mm、5 mm、7 mm前表面及3 mm后表面的|SIA|呈负相关(B=-0.261,P=0.047;B=-0.387,P=0.016;B=-0.323,P=0.009;B=-0.297,P=0.041;B=-0.085,P=0.049),而与3 mm前表面XSIA、5 mm、7 mm前表面YSIA呈正相关(B=0.347,P=0.040;B=0.318,P=0.034;B=0.403,P=0.010);AL与3 mm、5 mm后表面的|SIA|呈负相关(B=-0.023,P=0.021;B=-0.034,P=0.030)。结论在进行白内障超声乳化手术时,应考虑患者的眼部生物参数,如眼轴长度、角膜直径等对SIA的影响。

关键词：白内障超声乳化术源性散光角膜后表面眼轴长度角膜直径

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自控系统在秦皇岛污水处理厂的应用

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仪器仪表标准化与计量 2006年第4期 43-45页

作者：肖顺利胡宝琦中自控环境工程有限公司北京市100083 秦皇岛市第三污水处理厂秦皇岛市066000

通过秦皇岛海港区污水处理厂工程实例,详细介绍自控系统的构成,主要工艺部分自动控制的实现方法和运行过程中的改进。

关键词：自控系统 PLC 现场总线

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复合材料层板疲劳过程中疲劳寿命计的电阻变化规律研究

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数据采集与处理 1999年第2期14卷 204-209页

作者：周克印陶宝祺胡明敏南京航空航天大学测试工程系

采用疲劳寿命计对复合材料层板的疲劳过程进行了监测，研究了复合材料层板在单级和多级载荷下的疲劳累积损伤与疲劳寿命计电阻变化之间的关系。结果表明疲劳寿命计的输出电阻的累积变化能较好地反映层板的疲劳状态。

关键词：复合材料层板疲劳过程疲劳寿命计电阻变化

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Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi Guo Bin hu Haiwen Luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

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Co/Co_(7)Fe_(3)heterostructures with controllable alloying degree on carbon spheres as bifunctional electrocatalyst forrechargeable zinc-air batteries

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 476-487页

作者： Junkang Chen Yongyue Zhuang Yanxin Qiao Yu Zhang Aihua Yuan hu Zhou School of Materials Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China School of Environmental and Chemical Engineering Jiangsu University of Science and TechnologyZhenjiang 212003China

Exploring efficient and nonprecious metal electrocatalysts of oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)is crucial for developing rechargeable zinc-air batteries(ZABs).Herein,an alloying-degree control strategy was employed to fabricate nitrogen-doped carbon sphere(NCS)decorated with dual-phase Co/Co_(7)Fe_(3)heterojunctions(CoFe@NCS).The phase composition of materials has been adjusted by controlling the alloying *** optimal CoFe_(0.08)@NCS electrocatalyst displays a half-wave potential of 0.80 V for ORR and an overpotential of 283 mV at 10 mA·cm^(-2)for OER in an alkaline *** intriguing bifunctional electrocatalytic activity and durability is attributed to the hierarchically porous structure and interfacial electron coupling of highly-active Co_(7)Fe_(3)alloy and metallic Co *** the CoFe_(0.08)@NCS material is used as air-cathode catalyst of rechargeable liquid-state zinc-air battery(ZAB),the device shows a high peak power-density(157 mW·cm^(-2))and maintains a stable voltage gap over 150 h,outperforming those of the benchmark(Pt/C+RuO_(2))-based *** particular,the as-fabricated solid-state flexible ZAB delivers a reliable compatibility under different bending *** work provides a promising strategy to develop metal/alloy-based electrocatalysts for the application in renewable energy conversion technologies.

关键词： bifunctional electrocatalysts oxygen reduction reaction oxygen evolution reaction zinc-air battery metal/alloy carbon sphere

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Photo‑Energized MoS_(2)/CNT Cathode for High‑Performance Li–CO_(2)Batteries in a Wide‑Temperature Range

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Nano-Micro Letters 2025年第1期17卷 160-175页

作者： Tingsong hu Wenyi Lian Kang hu Qiuju Li Xueliang Cui Tengyu Yao Laifa Shen Jiangsu Key Laboratory of Materials and Technologies for Energy Storage College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Li–CO_(2) batteries are considered promising energy storage systems in extreme environments such as Mars;however,severe performance degradation will occur at a subzero temperature owning to the sluggish reaction ***,a photo-energized strategy adopting sustainable solar energy in wide working temperature range Li–CO_(2) battery was achieved with a binder-free MoS_(2)/carbon nanotube(CNT)photo-electrode as *** unique layered structure and excellent photoelectric properties of MoS_(2) facilitate the abundant generation and rapid transfer of photo-excited carriers,which accelerate the CO_(2) reduction and Li_(2)CO_(3) decomposition upon *** illuminated battery at room temperature exhibited high discharge voltage of 2.95 V and mitigated charge voltage of 3.27 V,attaining superior energy efficiency of 90.2%and excellent cycling stability of over 120 *** at an extremely low temperature of−30℃,the battery with same electrolyte can still deliver a small polarization of 0.45 V by the photoelectric and photothermal synergistic mechanism of MoS_(2)/CNT *** work demonstrates the promising potential of the photo-energized wide working temperature range Li–CO_(2) battery in addressing the obstacle of charge overpotential and energy efficiency.

关键词： Li-CO_(2)batteries Photo-energized Wide operation-temperature Kinetics MoS_(2)

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溶剂脱沥青组合工艺生产重交通道路沥青

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石化技术与应用 2006年第6期24卷 477-480,497页

作者：易发军罗勇傅徐刚胡宝其谢斌中国石化荆门分公司环保车间湖北荆门448000

中国石化荆门分公司以江汉-阿曼混合原油和江汉-鲁宁混合原油为原料,分别采用减压蒸馏—丙烷脱沥青和减压蒸馏—添加催化裂化油浆—丙烷脱沥青工艺,生产出符合SH 0522—2000的100号道路沥青。结果表明,江汉-阿曼混合原油减压渣油中掺兑... 详细信息

中国石化荆门分公司以江汉-阿曼混合原油和江汉-鲁宁混合原油为原料,分别采用减压蒸馏—丙烷脱沥青和减压蒸馏—添加催化裂化油浆—丙烷脱沥青工艺,生产出符合SH 0522—2000的100号道路沥青。结果表明,江汉-阿曼混合原油减压渣油中掺兑质量分数为30%的催化裂化油浆后,脱油沥青的各项性能均满足AH-70或AH-90重交通道路沥青的要求,而且薄膜烘箱试验表明,试样延度超过标准要求。

关键词：重交通道路沥青原油催化裂化油浆脱油沥青针入度延度

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Electrochemical conversion of methane to bridge the gap in the artificial carbon cycle

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Journal of Energy Chemistry 2025年第1期100卷 286-308页

作者： Yuhao Peng Yuefeng Song Ihar Razanau Juanxiu Xiao Wei Xiao Di hu Guoxiong Wang College of Chemistry and Molecular Sciences Hubei Key Laboratory of Electrochemical Power Sources Wuhan University State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy iChEM (Collaborative Innovation Center of Chemistry for Energy Materials) Dalian Institute of Chemical Physics Chinese Academy of Sciences Laboratory of Physical-Chemical Technologies SSPA Scientific and Practical Materials Research Centre of NAS of Belarus State Key Laboratory of Marine Resources Utilization in South China Sea Collaborative Innovation Center of Marine Science and Technology School of Marine Science and Engineering Hainan University Department of Chemical and Environmental Engineering University of Nottingham Ningbo China

Methane, an abundant one-carbon（C1） resource, is extensively used in the industrial production of vital fuels and value-added chemicals. However, current industrial methane conversion technologies are energy-and carbon-intensive, mainly due to the high activation energy required to break the inert C–H bond, low selectivity, and problematic side reactions, including CO2emissions and coke deposition. Electrochemical conversion of methane（ECM） using intermittent renewable energy offers an attractive solution, due to its modular reactor design and operational flexibility across a broad spectrum of temperatures and pressures. This review emphasizes conversion pathways of methane in various reaction systems, highlighting the significance and advantages of ECM in facilitating a sustainable artificial carbon cycle. This work provides a comprehensive overview of conventional methane activation mechanisms and delineates the complete pathways of methane conversion in electrolysis contexts. Based on surface/interface chemistry, this work systematically analyzes proposed reaction pathways and corresponding strategies to enhance ECM efficiency towards various target products, including syngas, hydrocarbons, oxygenates, and advanced carbon materials. The discussion also encompasses opportunities and challenges for the ECM process, including insights into ECM pathways, rational electrocatalyst design, establishment of benchmarking protocols, electrolyte engineering, enhancement of CH4conversion rates, and minimization of CO2emission.

关键词： Methane Electrochemical conversion Reaction mechanism Catalyst design Electrode Electrocatalysis

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A Novel Model for Describing Rail Weld Irregularities and Predicting Wheel-Rail Forces Using a Machine Learning Approach

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 555-577页

作者： Linlin Sun Zihui Wang Shukun Cui Ziquan Yan Weiping hu Qingchun Meng State Key Laboratory of High-Speed Railway Track System China Academy of Railway Sciences Corporation LimitedBeijing100081China Railway Engineering Research Institute China Academy of Railway Sciences Corporation LimitedBeijing100081China School of Aeronautic Science and Engineering Beihang UniversityBeijing100191China

Rail weld irregularities are one of the primary excitation sources for vehicle-track interaction dynamics in modern high-speed *** can cause significant wheel-rail dynamic interactions,leading to wheel-rail noise,component damage,and *** researchers have employed the vehicle-track interaction dynamic model to study the dynamic interactions between wheel and rail induced by rail weld geometry ***,the cosine wave model used to simulate rail weld irregularities mainly focuses on the maximum value and neglects the geometric *** this study,novel theoretical models were developed for three categories of rail weld irregularities,based on measurements of the high-speed railway from Beijing to *** vertical dynamic forces in the time and frequency domains were compared under different running *** forces generated by the rail weld irregularities that were measured and modeled,respectively,were compared to validate the accuracy of the proposed ***,based on the numerical study,the impact force due to rail weld irrregularity is modeled using an Artificial Neural Network(ANN),and the optimum combination of parameters for this model is *** results showed that the proposed model provided a more accurate wheel/rail dynamic evaluation caused by rail weld irregularities than that established in the *** ANN model used in this paper can effectively predict the impact force due to rail weld irrregularity while reducing the computation time.

关键词： Rail weld irregularity high-speed railway vehicle-track coupled dynamics wheel/rail dynamic vertical force artificial neural networks

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