检索结果-南通市图书馆

Hypoxia Affects Autophagy in Human Umbilical Vein Endothelial Cells via the IRE1 Unfolded Protein Response

在线全文

学校读者我要写书评

暂无评论

Current Medical Science 2023年第4期43卷 689-695页

作者： Zi-qi TAO bao-zhu wei Min ZHAO Xin-xin ZHANG Ya ZHONG Jing WAN Department of Cardiology Wuhan University Zhongnan HospitalWuhan 430072China School of Basic Medical Sciences Wuhan UniversityWuhan 430072China Department of Cardiology Wuhan No.1 HospitalWuhan 430030China

Objective:The purpose of this study was to investigate the role of the unfolded protein response,specifically the inositol-requiring enzyme 1(IRE1)signaling pathway,in hypoxia-induced autophagy in human umbilical venous endothelial cells(HUVECs).Methods:The expression of IRE1 and autophagy relative protein in HUVECs with hypoxia was explored by Western blotting,qRT-PCR and confocal ***,we evaluated the biological effects of HUVECs by tube formation assay and wound healing assay in ***,we examined the function of IRE1 in local blood vessels through animal models,Results:Hypoxia activated the IRE1 signaling pathway and induced autophagy in a time-dependent manner in HUVECs and further influenced the biological effects of *** injection of IRE1 inhibitors inhibited local vascular autophagy levels and lipid accumulation in model ***:Hypoxia can induce autophagy and activate the IRE1 signaling pathway in HUVECs and the IRE1 signaling pathway is involved in autophagy in hypoxic conditions.

关键词： hypoxia autophagy endoplasmic reticulum stress unfolded protein response IREl JNK

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie Wang wei Wang Xuheng Chen Junfang bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

在线全文

学校读者我要写书评

暂无评论

Java网络传输中字符编码问题的研究

计算机工程与应用 2007年第4期43卷 93-95页

作者：包竹苇李淼张建中国科学院合肥智能机械研究所合肥230031

针对Java客户端与服务器端通信,客户端浏览器显示等中文字符编码常常出现编解码错误、显示乱码的问题,从操作系统内部,Java虚拟机和网络传输过程进行研究,分析各种字符编码的表现形式,服务器端Servlet缺省字符集等,找出了问题的根源;提... 详细信息

针对Java客户端与服务器端通信,客户端浏览器显示等中文字符编码常常出现编解码错误、显示乱码的问题,从操作系统内部,Java虚拟机和网络传输过程进行研究,分析各种字符编码的表现形式,服务器端Servlet缺省字符集等,找出了问题的根源;提出在Java网络传输中中文字符编码问题的解决方法,并有效地应用于农业专家系统开发平台(DET6.0)的网络发布和知识推理中。

关键词： Java虚拟机网络传输中文编码 DET

Boosting Oxygen Evolution Reaction Performance on NiFe‑Based Catalysts Through d‑Orbital Hybridization

在线全文

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第1期17卷 281-292页

作者： Xing Wang wei Pi Sheng Hu Haifeng bao Na Yao wei Luo State Key Laboratory of New Textile Materials and Advanced Processing Technology Key Laboratory of New Textile Materials and Applications of Hubei ProvinceSchool of Materials Science and EngineeringWuhan Textile UniversityWuhan 430200People’s Republic of China College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072People’s Republic of China

Anion-exchange membrane water electrolyzers(AEMWEs)for green hydrogen production have received intensive attention due to their feasibility of using earth-abundant NiFe-based *** introducing a third metal into NiFe-based catalysts to construct asymmetrical M-NiFe units,the d-orbital and electronic structures can be adjusted,which is an important strategy to achieve sufficient oxygen evolution reaction(OER)performance in ***,the ternary NiFeM(M:La,Mo)catalysts featured with distinct M-NiFe units and varying d-orbitals are reported in this *** and theoretical calculation results reveal that the doping of La leads to optimized hybridization between d orbital in NiFeM and 2p in oxygen,resulting in enhanced adsorption strength of oxygen intermediates,and reduced rate-determining step energy barrier,which is responsible for the enhanced OER *** critically,the obtained NiFeLa catalyst only requires 1.58 V to reach 1 A cm^(−2) in an anion exchange membrane electrolyzer and demonstrates excellent long-term stability of up to 600 h.

关键词： NiFe-based catalysts d-orbital coupling Oxygen evolution reaction Anion exchange membrane electrolyzer

在线全文

学校读者我要写书评

暂无评论

甘蔗种植深耕深松技术应用效果试验

广西农业科学 2006年第5期37卷 520-521页

作者：韦宝珠柳江县土博镇糖业站广西柳州545108

甘蔗种植深耕深松技术是甘蔗优质高产、抗旱抗寒、抗倒伏、保水保肥栽培的重要措施之一。2005年对蔗地进行拖拉机深耕深松与牛耕对比试验，结果表明：使用48KW中型拖拉机悬挂深耕犁、深松机进行深耕深松作业，甘蔗出苗率比牛耕提高19．... 详细信息

甘蔗种植深耕深松技术是甘蔗优质高产、抗旱抗寒、抗倒伏、保水保肥栽培的重要措施之一。2005年对蔗地进行拖拉机深耕深松与牛耕对比试验，结果表明：使用48KW中型拖拉机悬挂深耕犁、深松机进行深耕深松作业，甘蔗出苗率比牛耕提高19．3％，分蘖率提高28．9％，根数增多3．8条／株，根长增21．1cm，根重增19.8g，土壤含水量增加0．5％～1．5％，干旱时达1．7％；每公顷增产原料蔗18．15t，增值4719元。

关键词：甘蔗深耕深松应用效果

在线全文

学校读者我要写书评

暂无评论

高桩码头增加钢管桩沉桩入土深度的施工措施

水运工程 2019年第2期 196-199页

作者：魏宝柱王凤杰丹东港集团有限公司辽宁丹东118300

在丹东港大东港区317~#高桩码头工程中,为增加钢管桩在卵石层中的入土深度,满足桩基嵌固长度要求,通过采用增加外箍的开口桩尖,有效缩减了沉桩过程中卵石层的侧摩阻力,入土深度增加2 m以上,侧模阻力在沉桩后30d逐渐恢复,满足桩基承载力... 详细信息

在丹东港大东港区317~#高桩码头工程中,为增加钢管桩在卵石层中的入土深度,满足桩基嵌固长度要求,通过采用增加外箍的开口桩尖,有效缩减了沉桩过程中卵石层的侧摩阻力,入土深度增加2 m以上,侧模阻力在沉桩后30d逐渐恢复,满足桩基承载力要求。结果表明,增加外箍桩尖能够有效缩减施工过程中卵石的侧摩阻力,增加桩入土深度,满足嵌固长度要求。

关键词：高桩码头钢管桩入土深度

Magnetic resonance imaging evaluation and nuclear receptor binding SET domain protein 1 mutation in the Sotos syndrome with attention-deficit/hyperactivity disorder

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第2期13卷 5-9页

作者： wei zhu Shanghai XiRong Information Science and Technology Co. LtdNational Science and Technology ParkSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China

Sotos syndrome is characterized by overgrowth features and is caused by alterations in the nuclear receptor binding SET domain protein 1 ***/hyperactivity disorder(ADHD)is considered a neurodevelopment and psychiatric disorder in *** characteristics and clinical presentation could play an important role in the diagnosis of Sotos syndrome and *** resonance imaging(MRI)has been used to assess medical images in Sotos syndrome and *** images process is considered to display in MRI while wavelet fusion has been used to integrate distinct images for achieving more complete information in single image in this *** the future,genetic mechanisms and artificial intelligence related to medical images could be used in the clinical diagnosis of Sotos syndrome and ADHD.

关键词： Sotos syndrome Attention-deficit/hyperactivity disorder Genetic mutation Magnetic resonance imaging Wavelet fusion

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

计算应力强度因子的离散分离变量法(英文)

计算物理 2000年第5期17卷 483-496页

作者：韩厚德黄忠亿包维柱清华大学数学科学系北京100084

提出一种用于数值求解带有一条边界裂纹的多角形区域上的Navier’s方程组边值问题的半离散方法。做一个适当的坐标变换后 ,将原边值问题化为半无限长条上的不连续系数问题。将其半离散化以后 ,等价于一个常系数常微分方程组的边值问题... 详细信息

提出一种用于数值求解带有一条边界裂纹的多角形区域上的Navier’s方程组边值问题的半离散方法。做一个适当的坐标变换后 ,将原边值问题化为半无限长条上的不连续系数问题。将其半离散化以后 ,等价于一个常系数常微分方程组的边值问题。进一步 ,用直接法来求解这个边值问题 ,便得到原问题的半离散近似解。值得指出的是 ,这个用分离变量形式给出的半离散近似解自然地具有原问题的奇性。数值例子显示 ,用该方法可以很方便地计算出在裂纹顶端的应力强度因子的近似值。

关键词：离散分离变量法应力强度因子 NAVIER'S方程组

Sequence-activated chemiluminescence probes: programmable illumination for high-contrast in vivo sensing and imaging

在线全文

学校读者我要写书评

暂无评论

Science China Chemistry 2025年第01期 26-34页

作者： Yutao Zhang Juan Li wei-Hong zhu Zhiqian Guo Shanghai Key Laboratory of Functional Materials Chemistry Joint International Research Laboratory of Precision Chemistry and Molecular Engineering Institute of Fine Chemicals School of Chemistry and Molecular Engineering East China University of Science and Technology State Key Laboratory of Bioreactor Engineering Shanghai Frontier Science Research Base of Optogenetic Techniques for Cell MetabolismEast China University of Science & Technology

Sequence-activated chemiluminescence(CL) technique offers a unique approach to detecting specific biomolecules or cellular events with high sensitivity and spatial resolution. The fundamental principle behind sequence-activated CL probes involves tailoring highly-controllable CL signals in response to specific sequences or events of interest, thus enabling high-contrast signals under complex physiological conditions. This sequential activation could be triggered by enzymes, reactive oxygen species(ROS), biothiols or changes in the microenvironment. These unique sequence-activated CL probes bestow several advantages, including minimal background, deep-tissue penetration, and the ability of non-invasive or minimally invasive detection. The sequence-activated CL techniques represent a significant advancement in molecular imaging and diagnostics. In this mini-review, we focus on the latest developments in sequential CL probes, addressing the technical challenges and discussing the future trajectory by harnessing CL signaling and molecular recognition.

关键词：

同方期刊数据库