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Continuous versus bolus cardiac output monitoring during orthotopic liver transplantation

Hepatobiliary & Pancreatic Diseases International 2008年第2期7卷 138-144页

作者： bao, fang-ping Wu, Jian Zhejiang Univ Sch Med Dept Anesthesiol Affiliated Hosp 1 Hangzhou 310003 Zhejiang Peoples R China

BACKGROUND: Cardiac output monitoring is important for critical patients. This study aimed to determine the delayed response of continuous cardiac output (CCO) thermodilution measurement, whether CCO and bolus cardiac output (BCO) thermodilution agree sufficiently to be used interchangeably, and whether CCO monitoring is reliable for patients undergoing liver transplantation. METHODS: Thirteen patients undergoing liver transplantation without veno-venous bypass were studied (37-66 years old, weight 46-75 kg). Continuous and bolus thermodilution measurements were performed at predefined time points using an 'Opti-Q' SvO(2)/CCO monitor (Abbott Laboratories, North Chicago, IL, USA). Bias and 95% limits of agreement were calculated according to Bland and Altman analysis. The limits of agreement by which two methods are judged to be interchangeable were defined in advance as +/-(13%X BCO(mean)) L/min. The repeatability and relative error of CCO, and the differences between CCO and the mean of the two measurements were calculated. RESULTS: Cardiac output measurements yielded 196 data pairs with ranges of 1.9 to 17.9 L/min for CCO and 2.1 to 18.3 L/min for BCO. The response time of CCO was delayed in the early phases after caval clamping and after reperfusion. At most of the measurement points, bias and 95% limits of agreement were -0.18 +/- 1.91 L/min. 95% limits of agreement did not fall within the predetermined limits of agreement of +/- 1.14 L/min. The repeatability coefficient of CCO was 0.36 L/min and the relative error was 4.6 +/- 4.7%. The mean difference between CCO and the average of the two methods was -0.09 L/min (0.49 L/min). CONCLUSIONS: In patients undergoing liver transplantation, the delayed response of CCO limits its application during the early phases after caval clamping and after reperfusion of the graft. The two methods are not interchangeable even in hemodynamic stability. Continuous thermodilution monitoring, however, is reliable or acceptable for c

关键词： cardiac output thermodilution anesthesia liver transplantation

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Dynamics of vascular volume and hemodilution of lactated Ringer’s solution in patients during induction of general and epidural anesthesia

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2006年第9期7卷 738-744页

作者： LI Yu-hong LOU Xian-feng bao fang-ping Department of Anesthesiology the First Affiliated Hospital School of Medicine Zhejiang University Hangzhou 3 10003 china Department of Orthopedics the First Affiliated Hospital School of Medicine Zhejiang university Hangzhou 310003 china

Objective： To investigate the dynamics of vascular volume and the plasma dilution of lactated Ringer＇s solution in patients during the induction of general and epidural anesthesia. Methods： The hemodilution of i.v. infusion of 1000 ml of lactated Ringer＇s solution over 60 min was studied in patients undergoing general （n=31） and epidural （n= 22） anesthesia. Heart rate, arterial blood pressure and hemoglobin （Hb） concentration were measured every 5 rain during the study. Surgery was not started until the study period had been completed. Results： General anesthesia caused the greater decrease of mean arterial blood pressure （MAP）（mean 15% versus 9%; P〈0.01） and thereby followed by a more pronounced plasma dilution, blood volume expansion （VE） and blood volume expansion efficiency （VEE）. A strong linear correlation between hemodilution and the reduction in MAP （r=-0.50;P〈0.01） was found. At the end of infusion, patients undergoing general anesthesia retained 47% （SD 19%） of the infused fluid in the circulation, while epidural anesthesia retained 29% （SD 13%）（P〈0.001）. Correspondingly, a fewer urine output （mean 89 ml versus 156 ml; P〈0.05） and extravascular expansion （454 ml versus 551 ml; P〈0.05） were found during general anesthesia. Conclusion： We concluded that the induction of general anesthesia caused more hemodilution, volume expansion and volume expansion efficiency than epidural anesthesia, which was triggered only by the lower MAP.

关键词： Hemodilution Volume expansion Ringer's solution General anesthesia Epidural anesthesia

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New Exact Solutions and Localized Structures for (3+1)-Dimensional Burgers System

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Communications in Theoretical Physics 2008年第4期49卷 955-959页

作者： LI Jiang-Bo MA Song-Hua REN Qing-bao fang Jian-ping ZHENG Chun-Long College of Mathematics and Physics Lishui University Lishui 323000 China

With an extended mapping approach and a linear variable separation method, new families of variable separation solutions （including solitary wave solutions, periodic wave solutions, and rational function solutions） with arbitrary functions for （3＋1）-dimensionai Burgers system is derived. Based on the derived excitations, we obtain some novel localized coherent structures and study the interactions between solitons.

关键词： extended mapping approach variable separation method (3+1)-dimensional Burgers system localized coherent structures the interactions between solitons

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Gender Affects the Median Effective Dose and 95% Effective Dose of Oxycodone for Blunting the Hemodynamic Response to Tracheal Intubation in Narcotic-Naive Adult Patients

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Chinese Medical Journal 2018年第16期131卷 1958-1963页

作者： Xian-Hui Kang fang-ping bao Hong-Gang Zhang Dan-Jun Yu Ke Ha Qing Xie Sheng-Mei Zhu Department of Anesthesiology The First Affiliated Hospital College of Medicine Zhejiang University Hangzhou Zhejiang 310003 China Department of Anesthesiology Changxing Hospital of Traditional Chinese Medicine Changxing County Huzhou Zhejiang 313100 China

Background： Intravenous （IV） oxycodone has been used at induction to prevent an intubation reaction. The aims of the current study were to calculate the median effective dose （ED50） and the 95% effective dose （ED95） of an IV bolus ofoxycodone that blunts the hemodynamic response to tracheal intubation with propofol according to gender and to observe the adverse events of induction-dose oxycodone. Methods： Adult patients who required general anesthesia and tracheal intubation were enrolled. Tracheal intubation was performed using unified TD-C-IV video laryngoscopy and an ordinary common endotracheal tube. Dixon＇s up-and-down method was used to obtain ED50, data for women and men separately. The initial dose of oxycodone was 0.2 mg/kg for women and 0.3 mg/kg for men （step size was 0.01 mg/kg）. Next, a dose-response curve from the probit analysis was generated to determine the ED50 and ED95 to blunt the intubation reaction in female and male patients. Adverse events following oxycodone injection were observed for 5 ,in before propofol injection. Results： Sixty-three patients were analyzed, including 29 females and 34 males. According to the probit analysis, the ED50, and ED95 of oxycodone required to blunt the intubation reaction in women were 0.254 mg/kg （95% confidence interval [CI], 0.220-0.328 mg/kg） and 0.357 mg/kg （95% （21, 0.297-2.563 mg/kg）, respectively. In men, the ED50 and ED95 were 0.324 mg/kg （95% CL 0.274-0.381 mg/kg） and 0.454 mg/kg （95% CI, 0.384-2.862 mg/kg）, respectively. Men required 28% more oxycodone than women for induction （P 〈 0.01 ）. The most common adverse events were dizziness （87.3%）, vertigo （66.7%）, sedation （74.6%）, and respiratory depression （66.7%）. Conclusions： Oxycodone can be used for induction to prevent intubation reactions. Gender affected the ED50 and ED95 ofoxycodone for blunting the tracheal intuhation reaction.

关键词： Adverse Events Hemodynamics Induction Intubation Oxycodone

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区块链共识机制下海运物流运输管理模式和责任研究

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物流工程与管理 2021年第2期43卷 91-93页

作者：鲍方平扬州大学法学院江苏扬州225000

海运物流沿袭了陆路物流的所有基本特点,但因其运输风险大、运输时间长等特点使得二者在货物运输管理中又有所不同。传统海运物流运输管理制度在信息交流、货物管理和交通运输等方面存在诸多缺陷,而区块链技术的提出和应用能作出有效弥... 详细信息

海运物流沿袭了陆路物流的所有基本特点,但因其运输风险大、运输时间长等特点使得二者在货物运输管理中又有所不同。传统海运物流运输管理制度在信息交流、货物管理和交通运输等方面存在诸多缺陷,而区块链技术的提出和应用能作出有效弥补。共识机制是区块链技术的核心,区块链共识机制的去中心化、信用构造和不可篡改等特点,能有效克服契约自由泛滥的风险,优化海上物流运输管理模式,改进责任承认的合理性,保障交易效率和运输安全,顺应现代化海上交易灵活多变的趋势。

关键词：海上物流共识机制管理模式责任承担

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在中国实施院前心肺复苏需要人工通气

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浙江大学学报（医学版） 2014年第5期43卷 505-512页

作者：包芳萍潘渊明郑树森浙江大学医学院附属第一医院麻醉科浙江杭州310003 浙江大学医学院附属第一医院肝胆胰外科浙江杭州310003

心肺复苏（CPR）是针对心脏骤停的一系列救援措施用以挽救患者生命.及早有效的院前CPR是挽救患者生命的重要措施.近年来国际CPR的指南有较大改变,更重视通过胸外按压环节以维持循环,弱化了人工通气环节.单纯胸外按压而不需要人工通气的... 详细信息

心肺复苏（CPR）是针对心脏骤停的一系列救援措施用以挽救患者生命.及早有效的院前CPR是挽救患者生命的重要措施.近年来国际CPR的指南有较大改变,更重视通过胸外按压环节以维持循环,弱化了人工通气环节.单纯胸外按压而不需要人工通气的基础CPR广为流传.本文综述近现代CPR的发展及相关研究结果.考虑无氧6 min可导致脑损伤、在中国救护车到达现场和转运时间较长、单纯胸外按压容易疲劳等情况,我们认为在中国实施单纯胸外按压的CPR并不合适.一些非专业人员虽然感到口对口人工通气比较难实施,但是大部分还是愿意施行人工通气操作的.广泛开展公众CPR培训,提高对包括人工通气和胸外按压环节的CPR认知度和掌握度,以维持有效通气和循环是目前中国CPR发展的重点.

关键词：心肺复苏术呼吸,人工心脏按摩综述

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VCM含汞废水的处理与职业卫生分析

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中国氯碱 2014年第2期 36-38页

作者：王伟房宝平陕西北元化工集团有限公司陕西榆林719000

针对VCM合成生产过程中含汞废水,处理方法进行介绍,并重点提出了汞危害及防护对策。

关键词：含汞废水水质汞危害

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硬膜外阻滞与全身麻醉下老年患者乳酸钠林格氏液容量动力学的比较

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中华麻醉学杂志 2013年第11期33卷 1376-1379页

作者：徐建红李玉红张雄信包芳萍项燕祝胜美浙江大学医学院附属第一医院麻醉科杭州市310003

目的比较乳酸钠林格氏液用于硬膜外阻滞和全身麻醉下老年患者的容量动力学。方法择期手术的老年患者40例，性别不限，年龄66—86岁，体重45～86kg，ASA分级Ⅰ或Ⅱ级。硬膜外阻滞组（EA组，n=20）于硬膜外注射局麻药前10rain开始恒速静... 详细信息

目的比较乳酸钠林格氏液用于硬膜外阻滞和全身麻醉下老年患者的容量动力学。方法择期手术的老年患者40例，性别不限，年龄66—86岁，体重45～86kg，ASA分级Ⅰ或Ⅱ级。硬膜外阻滞组（EA组，n=20）于硬膜外注射局麻药前10rain开始恒速静脉输注乳酸钠林格氏液，全身麻醉组（GA组，n=20）于麻醉诱导前20min开始恒速静脉输注乳酸钠林格氏液，乳酸钠林格氏液的容量为1000ml，输注时间60min。每隔5min采集动脉血样，检测血红蛋白浓度，采用物质平衡规律动态分析公式计算血浆稀释度、单位体重血容量增加量及血容量扩张效率。结果与EA组比较，GA组输注乳酸钠林格氏液30—60min时血浆稀释度、单位体重血容量增加量及血容量扩张效率升高（P〈0．05或0．01）。结论与硬膜外阻滞相比，全身麻醉下老年患者乳酸钠林格氏液的血容量扩张效率更强。

关键词：麻醉硬膜外麻醉全身老年人乳酸钠晶体溶液补液疗法

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Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie Wang Wei Wang Xuheng Chen Junfang bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

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CaH2-promoted activity of Ni-carbonate interface for CO2 methanation

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Journal of Energy Chemistry 2025年第1期100卷 522-532页

作者： Jin-Peng Wang Guo-Cui Mao Hui-Lin Jiang bao-Xia Dong Yun-Lei Teng School of Chemistry and Chemical Engineering Yangzhou University

Transition metal-carbonate interfaces often act as active sites in heterogeneous catalytic *** interface between transition metal and metal carbonate exhibits a dynamic equilibrium during the CO2hydrogenation reaction,involving surface carbonate hydrogenation and ***,there have been few reports on engineering the activity of the interface between transition metal and alkaline earth metal carbonate for catalytic *** work demonstrated that the incorporation of CaH2in Ni/CaCO3enhances the CO2methanation activity of the *** CO2conversion for Ni/CaH2-CaCO3reached 68.5%at 400°C,which was much higher than that of the Ni/CaCO3（31.6%） and Ni/CaH2-CaO （42.4%） ***,the Ni/CaH2-CaCO3catalysts remained stable during the stability test for 24 h at 400°C and 8 *** research revealed that CaH2played a crucial role in promoting the activity of the Ni-carbonate interface for ***2could modify the electronic structure of Ni and tune the structural properties of CaCO3to generate medium basic sites （OH groups）,which are favorable for the activation of H2and ***-situ Fourier transform infrared spectroscopy （FTIR） analysis combined with density functional theory calculations demonstrated that CO2activation occurs at the hydroxyl group （OH） on the CaH2-modified Ni-carbonate surface,leading to the formation of CO3H****,our study has confirmed that CO2methanation over the Ni/CaH2-CaCO3catalysts proceeds via the formate pathway.

关键词： Metal hydride Ni catalysts Carbonate Metal-carbonate interface

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