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Petroleum Science 2024年第2期21卷 1171-1189页

作者： Kun-Peng Zhang Mian chen Chang-Jun Zhao Su Wang Yong-dong Fan State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China MOE Key Laboratory of Petroleum Engineering in China University of Petroleum Beijing102249China Beijing International Center for Gas Hydrate School of Earth and Space SciencesPeking UniversityBeijing100871China

A method for in-situ stress measurement via fiber optics was proposed. The method utilizes the relationship between rock mass elastic parameters and in-situ stress. The approach offers the advantage of long-term stress measurements with high spatial resolution and frequency, significantly enhancing the ability to measure in-situ stress. The sensing casing, spirally wrapped with fiber optic, is cemented into the formation to establish a formation sensing nerve. Injecting fluid into the casing generates strain disturbance, establishing the relationship between rock mass properties and treatment ***, an optimization algorithm is established to invert the elastic parameters of formation via fiber optic strains. In the first part of this paper series, we established the theoretical basis for the inverse differential strain analysis method for in-situ stress measurement, which was subsequently verified using an analytical model. This paper is the fundamental basis for the inverse differential strain analysis method.

关键词： In-situ stress Fiber optic Orthotropic elastic Differential evolution AbaQUS

Alkali-resistant NO_(x) reduction over FeVO_(4)/TiO_(2)catalysts via regulating the electron transfer between Fe and V

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Chinese Chemical Letters 2024年第2期35卷 489-495页

作者： Yunang dong Penglu Wang Xiangyu Liu Jiang Deng Aling chen Lupeng Han Dengsong Zhang International Joint Laboratory of Catalytic Chemistry State Key Laboratory of Advanced Special SteelCollege of SciencesShanghai UniversityShanghai 200444China

The presence of alkali metals in exhaust gas from stationary resources causes a grand challenge for the practical application of selective catalytic reduction(SCR)of NO_(x) with NH_(3).Here,alkali-resistant NO_(x) reduction has been successfully implemented via tailoring the electron transfer over Fe and V species on FeVO_(4)/TiO_(2)*** strong interaction between Fe and V induced electron transfer from V to Fe and strengthened the adsorption and activation of NH_(3)and NO over active VO_(x) *** the presence of K_(2)O,the strong electron withdrawing effect of Fe offset the electron donating effect of K on the VO_(x) species,thus protecting the active species VO_(x) to maintain the NO_(x) reduction *** enhanced adsorption and activation of NH_(3) allowed SCR reaction to proceed via E-R mechanism even after K_(2)O *** work elucidated the electronic effects on the alkali metals resistance of traditional ferric vanadate SCR catalysts and provided a promising strategy to design SCR catalysts with superior alkali resistance.

关键词： Air pollution control NO_(X)reduction Selective catalytic reduction Alkali metals Electron transfer

The Wnt-dependent and Wnt-independent functions of BCL9 in development,tumorigenesis,and immunity:Implications in therapeutic opportunities

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Genes & Diseases 2024年第2期11卷 701-710页

作者： Minjie Wu Heng dong Chao Xu Mengqing Sun Haojin Gao Fangtian Bu Jianxiang chen College of Pharmacy and Department of Hepatology Institute of Hepatology and Metabolic DiseasesThe Affiliated Hospital of Hangzhou Normal UniversityHangzhou Normal UniversityHangzhouZhejiang 311121China Laboratory of Cancer Genomics Division of Cellular and Molecular ResearchNational Cancer CentreSingapore 169610Singapore Key Laboratory of Elemene Class Anti-Cancer Chinese Medicines Engineering Laboratory of Development and Application of Traditional Chinese MedicinesCollaborative Innovation Center of Traditional Chinese Medicines of Zhejiang ProvinceHangzhou Normal UniversityHangzhouZhejiang 311121China

B-cell CLL/lymphoma 9(BCL9)is considered a key developmental regulator and a well-established oncogenic driver in multiple cancer types,mainly through potentiating the Wnt/β-catenin ***,increasing evidences indicate that BCL9 also plays multiple Wnt-independent ***,we summarized the updates of the canonical and non-canonical functions of BCL9 in cellular,physiological,or pathological ***,we also concluded that the targeted inhibitors disrupt the interaction ofβ-catenin with BCL9 reported recently.

关键词： BCL9 Development Immunity Multifaceted functions Therapeutic target Tumorigenesis

Long non-coding RNA H19 regulates neurogenesis of induced neural stem cells in a mouse model of closed head injury

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Neural Regeneration Research 2024年第4期19卷 872-880页

作者： Mou Gao Qin dong Zhijun Yang Dan Zou Yajuan Han Zhanfeng chen Ruxiang Xu Department of Neurosurgery Sichuan Academy of Medical Sciences and Sichuan Provincial People's HospitalSchool of MedicineUniversity of Electronic Science and Technology of China Department of Neurosurgery Chinese PLA General Hospital Zhongsai Stem Cell Genetic Engineering Co. Ltd. Department of Neurology Fu Xing HospitalCapital Medical University

Stem cell-based therapies have been proposed as a potential treatment for neural regeneration following closed head *** previously reported that induced neural stem cells exert beneficial effects on neural regeneration via cell ***,the neural regeneration efficiency of induced neural stem cells remains *** this study,we explored differentially expressed genes and long non-coding RNAs to clarify the mechanism underlying the neurogenesis of induced neural stem *** found that H19 was the most downregulated neurogenesis-associated lnc RNA in induced neural stem cells compared with induced pluripotent stem ***,we demonstrated that H19 levels in induced neural stem cells were markedly lower than those in induced pluripotent stem cells and were substantially higher than those in induced neural stem cell-derived *** predicted the target genes of H19 and discovered that H19 directly interacts with mi R-325-3p,which directly interacts with Ctbp2 in induced pluripotent stem cells and induced neural stem *** H19 or Ctbp2 impaired induced neural stem cell proliferation,and mi R-325-3p suppression restored the effect of H19 inhibition but not the effect of Ctbp2 ***,H19 silencing substantially promoted the neural differentiation of induced neural stem cells and did not induce apoptosis of induced neural stem ***,silencing H19 in induced neural stem cell grafts markedly accelerated the neurological recovery of closed head injury *** results reveal that H19 regulates the neurogenesis of induced neural stem cells.H19 inhibition may promote the neural differentiation of induced neural stem cells,which is closely associated with neurological recovery following closed head injury.

关键词： closed head injury Ctbp2 induced neural stem cell lncRNA H19 miR-325-3p neurogenesis

Microbiome subsets determine tumor prognosis and molecular characteristics of clear-cell renal cell carcinoma:a multi-center integrated analysis of microbiome,metabolome,and transcriptome data

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Frontiers of Medicine 2024年第2期18卷 399-402页

作者： Wenjin chen Xiuwu Pan Wang Zhou Da Xu Jiaxin chen Keqin dong Weijie chen Brian Rini Xingang Cui Department of Urology Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghai200092China Department of Urology Third Affiliated Hospital of the Second Military Medical UniversityShanghai201805China Division of Hematology Oncology Vanderbilt University Medical CenterNashvilleTN37232USA

Dear editor,Patients with clear-cell renal cell carcinoma(ccRCC)potentially have a high recurrence rate of more than 40%[1].Patients receive radical or partial nephrectomy,sometimes assisted by targeted therapies or/and immune checkpoint inhibitors(ICIs),to improve overall survival(OS)[2].Large-cohort studies and large-scale human tissue sequencing have provided a series of molecular subtyping methods for precision medicine-based ccRCC risk stratification and therapeutic regimens,such as ClearCode34,the prognostic risk predictor[3],and seven subsets for ICI and angiogenesis blockade outcomes[4].However,these subtyping results are all based on human genomes without including the host microbiota,which may be non-negligible genome components.

关键词： editor negligible characteristics

Engineering FeOOH/Ni(OH)_(2) heterostructures on Ni_(3)S_(2)surface to enhance seawater splitting

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Rare Metals 2024年第5期43卷 1989-1998页

作者： chen Yang Ya-dong Li Li-Juan Cao Xi-Long Wang Han-Pu Liang Qingdao Institute of Bioenergy and Bioprocess Technology Chinese Academy of SciencesQingdao 266101China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China Sino-Danish College University of Chinese Academy of SciencesBeijing 100049China

The construction of highly stable and efficient electrocatalysts is desirable for seawater splitting but remains challenging due to the high concentration of Cl-in ***,FeOOH/Ni(OH)_(2)heterostructure supported on Ni_(3)S_(2)-covered nickel foam(Fe–Ni/Ni_(3)S_(2)/NF)was fabricated by hydrothermal and etching methods,as well as anodic oxidation *** electronic structure of FeOOH and Ni(OH)_(2)could be modulated after depositing FeOOH nanoparticles on Ni(OH)_(2)nanosheet,which greatly boosted the catalytic *** the catalyst used as an electrode for oxygen evolution reaction(OER),it needed low overpotentials of 266 and 368 m V to achieve current densities of 100 and 800 m A·cm^(-2),respectively,in 1 mol·L^(-1)KOH+seawater *** can operate continuously at 100 m A·cm^(-2)for 400 h without obvious ***,in situ generated SO_(4)^(2-)from inner Ni_(3)S_(2)during electrolysis process would accumulate on the surface of active sites to form passivation layers to repel Cl^(-),which seemed to be responsible for superior *** study not only synthesizes an OER catalyst for highly selective and stable seawater splitting,but also gives a novel approach for industrial hydrogen production.

关键词： Anodic oxidation Heterostructure Oxygen evolution reaction Seawater splitting

Deformation Characteristics of Hydrate-Bearing Sediments

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Journal of Ocean University of China 2024年第1期23卷 149-156页

作者： dong Lin LI Yanlong ZHANG Yajuan HU Gaowei LIAO Hualin chen Qiang WU Nengyou Key Laboratory of Gas Hydrate Ministry of Natural ResourcesQingdao Institute of Marine GeologyQingdao 266237China Laboratory for Marine Mineral Resources Laoshan LaboratoryQingdao 266237China College of Oceanography Hohai UniversityNanjing 210098China College of Petroleum Engineering China University of Petroleum(East China)Qingdao 266555China

The safe and efficient development of natural gas hydrate requires a deep understanding of the deformation behaviors of *** this study,a series of triaxial shearing tests are carried out to investigate the deformation properties of hydrate-bearing *** of volumetric and lateral strains versus hydrate saturation are analyzed *** indicate that the sediments with high hydrate saturation show dilative behaviors,which lead to strain-softening characteristics during *** volumetric strain curves have a tendency to transform gradually from dilatation to compression with the increase in effective confining *** easy prediction model is proposed to describe the relationship between volumetric and axial *** model coefficientβis the key dominating factor for the shape of volumetric strain curves and can be determined by the hydrate saturation and stress ***,a modified model is established for the calculation of lateral *** corresponding determination method is provided for the easy estimation of model coefficients for medium sand sediments containing *** study provides a theoretical and experimental reference for deformation estimation in natural gas hydrate development.

关键词： gas hydrate deformation characteristics volumetric strain lateral strain prediction model

Enhanced cyclic stability of partially disordered spinel cathodes through direct fluorination with gaseous fluorine

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Rare Metals 2024年第4期43卷 1635-1646页

作者： Yong-Nian Ma Ling-chen Kong Shao-Shan chen Yong Wang Li-dong Sun Cong Peng Meng-Meng Qin Yu Li Wei Feng Tianjin Key Laboratory of Composite and Functional Materials School of Materials Science and EngineeringTianjin UniversityTianjin300072China Institute of Advanced Technology and Equipment Beijing University of Chemical TechnologyBeijing100029China

Spinel-type cathodes are considered an optimal substitute for conventional layered oxide cathodes owing to their use of inexpensive and earth-abundant manganese as the redox-active ***,the introduction of cation disorder can effectively suppress the detrimental two-phase reaction to realize high capacities in a wide voltage ***,the continuous capacity decay during cycles has hindered the widespread application of these cathode *** fluorides exhibit excellent electrochemical stability at high voltage;therefore,in this study,the direct F2 gas reaction with a partially disordered spinel cathode(Li_(1.6)Mn_(1.6)O_(3.7)F_(0.3,)LMOF1.6)was initially applied to investigate the impacts of fluorination on the surface structure and electrochemical *** inorganic fluorinated layer,mainly containing LiF,was distributed uniformly on the surface of LMOF1.6nanoparticles after fluorination for an appropriate time without the turbulence caused by the valency of manganese cation,which improved the capacity retention and rate capability by the suppression of structural damage,parasitic reaction,and cation *** LMOF1.6cathode fluorinated for 0.5 h exhibited a capacity of283.6 mAh·g^(-1)at 50 mA·g^(-1)and an enhanced capacity retention of 29.6%after 50 cycles in the voltage range of1.5-4.8 V,as compared to the pristine LMOF1.6 with only27.9%capacity retention.

关键词： Spinel-type cathodes Direct fluorination Capacity retention ability High rate capability

Temperature-Dependent Tearing Behavior of Rubber Materials:Characterization and Modeling

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Acta Mechanica Solida Sinica 2024年第2期37卷 316-326页

作者： Qinyuan Yao Feilong Zhang Pan dong Ziyuan Zhao Yi He Weiguo Li Liming chen State Key Laboratory of Coal Mine Disaster Dynamics and Control Chongqing UniversityChongqing400044China College of Aerospace Engineering Chongqing UniversityChongqing400044China

With the increasingly widespread application of rubber in many fields,there is a growing demand for quantitative characterization of temperature-dependent mechanical properties in high-temperature service *** critical tearing energy is an important criterion for determining whether rubber materials will experience tearing instability,while tear strength is a key parameter for rubber materials to resist *** is necessary to quantitatively characterize their evolution with *** theoretical research mainly relies on fitting a large amount of experimental data,which is not convenient for engineering ***,in this work,a temperature-dependent critical tearing energy model is firstly developed based on the force-heat equivalence energy density *** model considers the equivalent relationship between the critical tearing energy required for crack instability propagation and the thermal energy stored in the rubber *** is demonstrated that our model has higher prediction accuracy when compared to other ***,combining with the Griffith fracture theory,temperature-dependent tear strength models applicable to three different crack modes are separately *** models are validated using experimental data for Mode I opening cracks and ModeⅢtearing cracks,and good consistency is ***,a quantitative analysis of the influence of elastic modulus on tear strength at different temperatures is *** work provides a reliable way for predicting temperature-dependent tearing instability behavior and offers beneficial suggestions for improving the tear strength of rubber materials at different temperatures.

关键词： Temperature-dependent Critical tearing energy Tear strength Rubber Theoretical model

A Three-Dimensional DEM Method for Trajectory Simulations of Rockfall under Irregular-Shaped Slope Surface and Rock Blocks

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Journal of Earth Science 2024年第1期35卷 306-312页

作者： Liang chen Weiqian Zeng Xianbiao Wang Yang Ye Yunfeng Ge dongming Gu Shan dong Huadong Engineering Corporation Limited Fuzhou 350003China Faculty of Engineering China University of GeosciencesWuhan 430074China badong National Observation and Research Station of Geohazards China University of GeosciencesWuhan 430074China

0 *** is a common geological hazard that poses a serious threat to residents and infrastructures(Gao et al.,2022;Ye et al.,2022).The precise prediction of rockfall trajectories is essential to the design of protection engineering structures of rockfall(Ma et al.,2021).The discrete element modelling(DEM)is increasingly used to analyse rockfall movement *** et al.(2022)used Rockyfor3D software to obtain the possible trajectory of falling rock blocks.

关键词： rock prediction hazard