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Maintaining moderate levels of hypochlorous acid promotes neural stem cell proliferation and differentiation in the recovery phase of stroke

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Neural Regeneration Research 2025年第3期20卷 845-857页

作者： Lin-Yan Huang Yi-De Zhang Jie Chen Hai-Di Fan Wan Wang bin Wang Ju-Yun Ma Peng-Peng Li Hai-Wei Pu Xin-Yian guo Jian-Gang shen su-Hua Qi school of Medical Technology Xuzhou Key Laboratory of Laboratory DiagnosticsXuzhou Medical UniversityXuzhouJiangsu ProvinceChina school of Pharmacy Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina Department of Laboratory Medicine Branch Hospital of Huai’an First People’s HospitalHuai’anJiangsu ProvinceChina Department of Laboratory Medicine the Affiliated Hospital of Xuzhou Medical UniversityXuzhouJiangsu ProvinceChina school of Chinese Medicine The University of Hong KongHong Kong Special Administrative RegionChina

It has been shown clinically that continuous removal of ischemia/reperfusion-induced reactive oxygen species is not conducive to the recovery of late ***,previous studies have shown that excessive increases in hypochlorous acid after stroke can cause severe damage to brain *** previous studies have found that a small amount of hypochlorous acid still exists in the later stage of stroke,but its specific role and mechanism are currently *** simulate stroke in vivo,a middle cerebral artery occlusion rat model was established,with an oxygen-glucose deprivation/reoxygenation model established in vitro to mimic *** found that in the early stage(within 24 hours)of ischemic stroke,neutrophils produced a large amount of hypochlorous acid,while in the recovery phase(10 days after stroke),microglia were activated and produced a small amount of hypochlorous ***,in acute stroke in rats,hypochlorous acid production was prevented using a hypochlorous acid scavenger,taurine,or myeloperoxidase inhibitor,4-aminobenzoic acid *** results showed that high levels of hypochlorous acid(200μM)induced neuronal apoptosis after oxygen/glucose deprivation/***,in the recovery phase of the middle cerebral artery occlusion model,a moderate level of hypochlorous acid promoted the proliferation and differentiation of neural stem cells into neurons and *** suggests that hypochlorous acid plays different roles at different phases of cerebral ischemia/reperfusion *** levels of hypochlorous acid(5 and 100μM)promoted nuclear translocation ofβ-*** transfection of single-site mutation plasmids,we found that hypochlorous acid induced chlorination of theβ-catenin tyrosine 30 residue,which promoted nuclear ***,our study indicates that maintaining low levels of hypochlorous acid plays a key role in the recovery of neurological function.

关键词： cell differentiation cerebral ischemia/reperfusion injury chlorination hypochlorous acid microglia neural stem cell neurogenesis nuclear translocation stroke β-catenin

Generalization of solovev's approach to finding equilibrium solutions for axisymmetric plasmas with flow

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Plasma science and Technology 2018年第3期20卷 19-32页

作者： M s CHU Yemin HU Wenfeng guo Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People's Republic of China Center for Magnetic Fusion Theory Chinese Academy of SciencesHefei 230031People's Republic of China

solovev's approach of finding equilibrium solutions was found to be extremely useful for generating a library of linear-superposable equilibria for the purpose of shaping *** set of solutions was subsequently expanded to include the vacuum solutions of Zheng,Wootton and solano,resulting in a set of functions{sOLOVEV_ZWs}that were usually used for all toroidally symmetric plasmas,commonly recognized as being able to accommodate any desired plasma shapes(complete-shaping capability).The possibility of extending the solovev approach to toroidal equilibria with a general plasma flow is examined *** found that the only meaningful extension is to plasmas with a pure toroidal rotation and with a constant Mach *** also show that the simplification ansatz made to the current profiles,which was the basis of the solovev approach,should be applied more systematically to include an internal boundary condition at the magnetic axis;resulting in a modified and more useful set{sOLOVEV_ZWsm}.Explicit expressions of functions in this set are given for equilibria with a quasi-constant current density profile,with a toroidal flow at a constant Mach number and with specific heat capacity *** properties of{sOLOVEV_ZWsm}are studied *** examples of achievable equilibria are *** the shaping capability of the set{sOLOVE_ZWsm}is quite extensive,it nevertheless still does not have complete shaping capability,particularly for plasmas with negative curvature points on the plasma boundary such as the doublets or indented bean shaped tokamaks.

关键词： theory plasma equilibrium plasma flow

Numerical study of equilibrium solutions for axisymmetric plasmas with toroidal flow obtained using solovev approach

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Plasma science and Technology 2019年第5期21卷 79-92页

作者： Yemin HU M s ZHU Wenfeng guo Institute of Plasma Physics Chinese Academy of SciencesHefei 230031People's Republic of China Center for Magnetic Fusion Theory Chinese Academy of SciencesHefei 230031People's Republic of China

solovev approach of finding equilibrium solutions,which was extended to include the vacuum solutions provided by Zheng,Wooton,and solano,was found extremely useful for the purpose of shaping *** extension to toroidal equilibria with a general plasma flow was examined theoretically in a companion paper by Chu,Hu and *** only meaningful extension was found for plasmas with a pure toroidal rotation and with a constant Mach number.A set of functions{sOLOVEV_ZWsm}was obtained which fixed location of the magnetic axis for equilibria with quasi-constant current density profile,with toroidal flow at constant Mach number and with specific heat capacity *** set{solovev_ZWsm}should have complete shaping capability for plasma shapes with positive curvature at the boundary;but not for plasmas with negative curvature boundary points,*** doublets or bean shaped *** report here extensive numerical studies showing the shaping capability of{solovev_ZWsm}for plasmas with pure toroidal rotations,including the change in topology of the solution when the rotation mach number *** plasma topology are the sphere(spheromaks);and the tokamaks(including the doublets).

关键词： solovev approach toroidal flow linear-superposable equilibria

Negative refractions by triangular lattice sonic crystals in partial band gaps

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Chinese Physics b 2015年第4期24卷 310-321页

作者： s.Alagoz b.b.Alagoz A.sahin s.Nur Department of Physics Inonu University Department of Electrical and Electronics Engineering Inonu University Vocational school of Health services Medical Imaging Techniques Inonu University

This study numerically demonstrates the effects of partial band gaps on the negative refraction properties of sonic crystal. The partial band gap appearing at the second band edge leads to the efficient transmissions of scattered wave envelopes in the transverse directions inside triangular lattice sonic crystal, and therefore enhances the refraction property of sonic crystal. Numerical simulation results indicate a diagonal guidance of coupled scattered wave envelopes inside crystal structure at the partial band gap frequencies and then output waves are restored in the vicinity of the output interface of sonic crystal by combining phase coherent scattered waves according to Huygens＇ principles. This mechanism leads to two operations for wavefront engineering： one is spatial wavefront shifting operation and the other is convex-concave wavefront inversion operation. The effects of this mechanism on the negative refraction and wave focalization are investigated by using the finite difference time domain （FDTD） simulations. This study contributes to a better understanding of negative refraction and wave focusing mechanisms at the band edge frequencies, and shows the applications of the slab comer beam splitting and sC-air multilayer acoustic system.

关键词： sonic crystal negative refraction wave focusing partial band gap

Perturbation and variational approach for the equation of state for hard-sphere and Lennard-Jones fluids

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Chinese Physics b 2012年第4期21卷 383-395页

作者： s. b. Khasare Department of Physics Science College Congress Nagar Nagpur India

The present work uses the concept of a scaled particle along with the perturbation and variation approach, to develop an equation of state （EOs） for a mixture of hard sphere （Hs）, Lennar-Jones （L J） fluids. A suitable flexible functional form for the radial distribution function G（R） is assumed for the mixture, with R as a variable. The function G（R） has an arbitrary parameter m and a different equation of state can be obtained with a suitable choice of m. For m = 0.75 and m = 0.83 results are close to molecular dynamics （MD） result for pure Hs and LJ fluid respectively.

关键词： equation of state Lennard-Jones potential hard-sphere potential liquid mixture com- puter simulation

Dynamics of the plane and solitary waves in a Noguchi network:Effects of the nonlinear quadratic dispersion

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Chinese Physics b 2020年第3期29卷 105-111页

作者： s A T Fonkoua M s Ngounou G R Deffo F b Pelap s b Yamgoue A Fomethe Unite de Recherche de Matiere Condensee d’Electronique et de Traitement du signal(UR-MACETs) Faculte des SciencesUniversite de DschangBP 67 DschangCameroun Unite de Recherche de Mecanique et de Modelisation des systemes Physiques(UR-2MsP) Faculte des SciencesUniversite de DschangBP 69 DschangCameroun Department of Physics Higher Teacher Training College BambiliUniversity of BamendaP.O.Box 39 BamendaCameroon

We consider a modified Noguchi network and study the impact of the nonlinear quadratic dispersion on the dynamics of modulated waves. In the semi-discrete limit, we show that the dynamics of these waves are governed by a nonlinear cubic schrodinger equation. From the graphical analysis of the coefficients of this equation, it appears that the nonlinear quadratic dispersion counterbalances the effects of the linear dispersion in the frequency domain. Moreover, we establish that this nonlinear quadratic dispersion provokes the disappearance of some regions of modulational instability in the dispersion curve compared to the results earlier obtained by Pelap et al.(Phys. Rev. E 91 022925(2015)). We also find that the nonlinear quadratic dispersion limit considerably affects the nature, stability, and characteristics of the waves which propagate through the system. Furthermore, the results of the numerical simulations performed on the exact equations describing the network are found to be in good agreement with the analytical predictions.

关键词： Noguchi network nonlinear quadratic dispersion modulational instability soliton

separation of hematite from banded hematite jasper(bHJ) by magnetic coating

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Journal of Central south University 2015年第2期22卷 437-444页

作者： subhashree singh H.sahoo s.s.Rath b.b.Palei b.Das CsIR-Institute of Minerals and Materials Technology

The separation of iron oxide from banded hematite jasper(bHJ) assaying 47.8% Fe, 25.6% si O2 and 2.30%Al2O3 using selective magnetic coating was studied. Characterization studies of the low grade ore indicate that besides hematite and goethite,jasper, a microcrystalline form of quartzite, is the major impurity associated with this ore. beneficiation by conventional magnetic separation technique could yield a magnetic concentrate containing 60.8% Fe with 51% Fe recovery. In order to enhance the recovery of the iron oxide minerals, fine magnetite, colloidal magnetite and oleate colloidal magnetite were used as the coating material. When subjected to magnetic separation, the coated ore produces an iron concentrate containing 60.2% Fe with an enhanced recovery of56%. The AFM studies indicate that the coagulation of hematite particles with the oleate colloidal magnetite facilitates the higher recovery of iron particles from the low grade bHJ iron ore under appropriate conditions.

关键词： banded hematite jasper ore selective coating oleate colloidal magnetite magnetic separation atomic force microscopy

A Comprehensive survey on Federated Learning Applications in Computational Mental Healthcare

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Computer Modeling in Engineering & sciences 2025年第1期142卷 49-90页

作者： Vajratiya Vajrobol Geetika Jain saxena Amit Pundir sanjeev singh Akshat Gaurav savi bansal Razaz Waheeb Attar Mosiur Rahman brij b.Gupta Institute of Informatics and Communication University of DelhiDelhi110021India Maharaja Agrasen College University of DelhiDelhi110096India Computer Engineering Ronin InstituteMontclairNJ 07043USA Department of Research and Innovation Insights2TechinfoJaipur302001India University Centre for Research and Development(UCRD) Chandigarh UniversityChandigarh140413India Management Department College of Business AdministrationPrincess Nourah bint Abdulrahman UniversityRiyadh11671Saudi Arabia CCRI&Department of Computer science and Information Engineering Asia UniversityTaichung413Taiwan symbiosis Centre for Information Technology(sCIT) Symbiosis International UniversityPune411057India Center for Interdisciplinary Research University of Petroleum and Energy Studies(UPES)Dehradun248007India

Mental health is a significant issue worldwide,and the utilization of technology to assist mental health has seen a growing *** aims to alleviate the workload on healthcare professionals and aid *** applications have been developed to support the challenges in intelligent healthcare ***,because mental health data is sensitive,privacy concerns have *** learning has gotten some *** research reviews the studies on federated learning and mental health related to solving the issue of intelligent healthcare *** explores various dimensions of federated learning in mental health,such as datasets(their types and sources),applications categorized based on mental health symptoms,federated mental health frameworks,federated machine learning,federated deep learning,and the benefits of federated learning in mental health *** research conducts surveys to evaluate the current state of mental health applications,mainly focusing on the role of Federated Learning(FL)and related privacy and data security *** survey provides valuable insights into how these applications are emerging and evolving,specifically emphasizing FL’s impact.

关键词： Depression emotional recognition intelligent healthcare systems mental health federated learning stress detection sleep behaviour

基于分子束外延技术可控制备bi原子团簇的研究

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原子与分子物理学报 2025年第2期42卷 79-84页

作者：马玉麟郭祥丁召贵州大学大数据与信息工程学院贵阳550025 贵州省微纳电子与软件技术重点实验室贵阳550025 半导体功率器件可靠性教育部工程研究中心贵阳550025

本研究基于分子束外延(MbE)技术在si(111)衬底表面成功制备金属bi原子团簇.首先,分别在100℃、125℃、150℃、175℃、200℃的生长温度下,制备了大小均一、密度不同的bi原子团簇.实验结果表明,可以通过改变生长温度来精细控制bi原子团簇... 详细信息

本研究基于分子束外延(MbE)技术在si(111)衬底表面成功制备金属bi原子团簇.首先,分别在100℃、125℃、150℃、175℃、200℃的生长温度下,制备了大小均一、密度不同的bi原子团簇.实验结果表明,可以通过改变生长温度来精细控制bi原子团簇的密度,当温度升高100℃,密度从1.05×10^(11)cm^(-2)降低至2.5×10^(7)cm^(-2),实现对团簇密度4个数量级的可控调节,并且发现bi原子团簇密度对生长温度的依赖性符合经典成核理论.其次,分别在10 s、15 s、20 s的沉积时长下,制备了密度相同、尺寸各异的bi原子团簇.实验结果表明,可以通过改变沉积时长来精细控制bi原子团簇的尺寸:当沉积时长增加10 s,高度和直径分别从8.5 nm和65 nm增大到13.7 nm和100 nm,实现对团簇尺寸在10 nm高度、80 nm直径范围的可控调节,并且发现bi原子团簇尺寸对沉积时长的依赖性符合晶体生长动力学.与分子束外延制备传统的Ⅲ族(Al,Ga,In)原子团簇做对比,这些结果可以为制备Ⅴ族原子团簇提供实验参考和指导,从而促进纳米级含bi材料的制备.

关键词：分子束外延 bi原子团簇生长温度沉积时长经典成核理论晶体生长动力学

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