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Cluster sampling methodology to evaluate immunization coverage

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World Journal of Methodology 2024年第3期14卷 78-89页

作者： Aishwarya Sharma rb Jain Jitesh Satija Aditi Sharma Avani Sharma Sudhir Shekhawat Department of Community Medicine School of Medical Sciences&ResearchSharda UniversityGreater Noida 201306UPIndia Department of Community Medicine World College of Medical Sciences&ResearchJhajjar 124103HaryanaIndia Department of Community Medicine ESIC Medical College&HospitalFaridabad 121012HaryanaIndia Department of Community Medicine Hamdard Institute of Medical Sciences&ResearchNew Delhi 110062India Department of Community Medicine Pt.B.D.Sharma Post Graduate Institute of Medical SciencesRohtak 124001HaryanaIndia Independent biostatistician Ghaziabad 201014UPIndia

bACKGROUND Immunization is a key component of primary health care and an indisputable human *** are critical to the prevention and control of infectious disease *** coronavirus disease 2019(COVID-19)pandemic and associated disruptions over the past two years have strained the health systems,with many children missing out on essential childhood *** To evaluate the immunization coverage among 12-23-month-old children in the rural areas of Community Health Centre(CHC)dighal and to determine the factors influencing the existing immunization *** A coverage evaluation survey was conducted according to the 30-cluster sampling technique,which is the standard methodology for such surveys devised by World Health Organization.A total of 300 children aged 12-23 months were included,whose immunization details were noted from their immunization *** Full immunization rate was noted in 86.7%of the children,with partial and non-immunized children accounting for 9%and 4.3%*** full immunization dropout rate was 4.2%.The common reasons for partial or non-immunization were family problem including illness of mother,vaccine not being available and child being *** of birth(P=0.014)and availability of immunization card(Pdictors of the immunization *** the study was conducted in 2020/2021,health services were disrupted due to the COVID-19 *** Due to the coverage being higher than the national average,it was concluded that the immunization coverage was optimal and not affected by the COVID-19 pandemic.

关键词： Immunization coverage Children COVID 19 pandemic Vaccines Family health Routine immunization

Robust hybrid bismuth perovskites as potential photocatalysts for overall water splitting

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Nano Research 2024年第5期17卷 4593-4601页

作者： Antonio J.Chacón-García Herme G.baldovi Artem A.babaryk Antonio Rodríguez-diéguez Sergio Navalón Yolanda Pérez Hermenegildo García Patricia Horcajada Advanced Porous Materials Unit IMDEA Energy InstituteAvda.Ramón y Cajal 328935 MóstolesMadridSpain Departamento de Química Universitat Politècnica de València46022 ValènciaSpain Departamento Química Inorgánica Universidad de Granada1807GranadaSpain Departamento de biología y Geología Física y Química Inorgánica.ESCET.Universidad Rey Juan Carlos28933 MóstolesMadridSpain Instituto de tecnología química CSIC-UPV Universitat Politècnica de València(UPV)46022Spain

Organic-inorganic hybrid perovskites have gained great attention as promising photocatalysts for hydrogen ***,due to their poor stability in water,the use of aqueous hydrohalic acid solutions is specifically required for an efficient hydrogen ***,three novel photoactive lead-free hybrid perovskites based on bismuth and triazolium cations(denoted as IEF-15,IEF-16,and IEF-17(IEF stands for IMDEA energy frameworks))were synthesized and fully characterized(structural,compositional,optical,etc.).Further,these solids were proposed as photocatalysts for the challenging gas phase overall water splitting(OWS)***,IEF-16 thin films exhibited a remarkable photocatalytic activity in both H_(2) and O_(2) evolution,as a consequence of its appropriate bandgap and energy-band alignment,achieving hydrogen evolution rates ofμmol·g_(H_(2))^(-)1846 and 360 after 24 h under ultraviolet-visible(UV-vis)irradiation or simulated solar irradiation,*** study additionally highlights the remarkable structural and photochemical stability of IEF-16 under different operational conditions(*** volume,irradiation and temperature),paving the way for green hydrogen production from OWS using perovskite-based photocatalysts.

关键词： bismuth-based hybrid perovskites thin films photocatalysis overall water splitting green hydrogen

Development and characterization of whey protein films incorporated with tarbush polyphenols and candelilla wax

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Food bioscience 2022年第1期45卷 1-7页

作者： Olga b.Alvarez-Perez Janeth M.ventura-Sobrevilla Cristian Torres-Leon Romeo Rojas-Molina raúl Rodríguez-Herrera Miguel A.Aguilar-Gonzalez Cristobal N.Aguilar bioprocesses and bioproducts Research Group Food Research DepartmentSchool of ChemistryUniversidad Autonoma de Coahuila25280SaltilloCoahuilaMexico School of Health Sciences Universidad Autonoma de Coahuila26090Piedras NegrasCoahuilaMexico School of Agronomy Research Center and Development for Food IndustryUniversidad Autonoma de Nuevo Leon6050General EscobedoNuevo LeonMexico Center for Research and Advanced Studies of the National Polytechnique Institute Parque Industrial Saltillo-Ramos ArizpeCoahuilaMexico

Edible films were prepared with whey protein incorporating candelilla wax,and glycerol in aqueous *** polyphenols were added as bioactive *** optimization based on the water vapor permeability(WVP)of the formulation was performed using a box-behnken *** films were characterized by the determination of WVP,moisture,solubility,color,antioxidant and antifungal *** electron microscopy(SEM)was also performed to observe the surface and cross-section *** lowest permeability values were found with concentrations of 1.27,0.3 and 0.5% of protein,wax and glycerol *** was proved that the addition of polyphenols into films causes a significant effect only on solubility and transparency *** films have suitable properties as a barrier for the goods they could be applied *** is proposed for use in foods such as fresh or minimally processed fruits and vegetables.

关键词： Edible films Whey protein Shelf life Candelilla wax Euphorbia antisyphilitica Fluorensia cernua polyphenols

One ring is sufficient to inhibit α-synuclein aggregation

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Neural Regeneration Research 2022年第3期17卷 508-511页

作者： Samuel Peña-Díaz Salvador ventura Institut de biotecnologia i biomedicina Universitat Autònoma de BarcelonaBellaterraSpain Departament de bioquímica i biologia Molecular Universitat Autònoma de BarcelonaBellaterraSpain InstitucióCatalana de Recerca i Estudis Avançats(ICREA) BarcelonaSpain

Parkinson's disease,the second most prevalent neurodegenerative disorder worldwide,is characterized by a progressive loss of dopaminergic neurons in substantia nigra pars compacta,causing motor *** disorder's main hallmark is the formation of intraneuronal protein inclusions,named Lewy bodies and *** major component of these arrangements is α-synuclein,an intrinsically disordered and soluble protein that,in pathological conditions,can form toxic and cell-to-cell transmissible amyloid *** α-synuclein aggregation has attracted significant effort in the search for a disease-modifying therapy for Parkinson's *** molecules like Synu Clean-D,epigallocatechin gallate,trodusquemine,or anle138 b exemplify this therapeutic ***,we describe a subset of compounds containing a single aromatic ring,like dopamine,ZPDm,gallic acid,or entacapone,which act as molecular chaperones against α-synuclein *** simplicity of their structures contrasts with the complexity of the aggregation process,yet the block efficiently α-synuclein assembly into amyloid fibrils,in many cases,redirecting the reaction towards the formation of non-toxic off-pathway ***,some of these compounds can disentangle mature α-synuclein amyloid *** simple structures allow structure-activity relationship analysis to elucidate the role of different functional groups in the inhibition of α-synuclein aggregation and fibril dismantling,making them informative lead scaffolds for the rational development of efficient drugs.

关键词： amyloid aromatic rings dopamine inhibition neurodegeneration oligomers Parkinson's disease protein aggregation α-synuclein

为波士顿非洲裔居民提供食品以帮助未经治疗的高血压成人终止高血压试验的基本原理和设计

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中华高血压杂志(中英文) 2024年第1期32卷 100-100页

作者： Turkson-Ocran RN Cluett JL Fitzpatrick SL Kraemer KM Mc Manus K Mukamal KJ Davis rb Elborki M Ferro K Ismail N Laura AE Larbi KF Castilla-Ojo N Grobman b Seager R Hines AL Miller ER Crews DC Juraschek SP 刘青

不健康的膳食是影响非洲裔成年人高血压差异的重要因素。终止高血压膳食疗法(dietary approaches to stop hypertension,DASH)的膳食模式可以降低血压,但食品荒漠的城市居民难以接触到DASH模式的食品,这是主要的障碍。方法:为波士顿非...

不健康的膳食是影响非洲裔成年人高血压差异的重要因素。终止高血压膳食疗法(dietary approaches to stop hypertension,DASH)的膳食模式可以降低血压,但食品荒漠的城市居民难以接触到DASH模式的食品,这是主要的障碍。方法:为波士顿非洲裔居民提供食品以帮助未经治疗的高血压成人终止高血压(Go Feshr,GF)研究是解决预防高血压的社会决定因素(addressing social determinants to prevent hypertension,RESTORE)网络的五个项目之一。

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Reciprocating sliding wear properties of sintered Al-b_(4)C composites

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International Journal of Minerals,Metallurgy and Materials 2022年第6期29卷 1261-1269页

作者： Mahmut Can Şenel Yusuf Kanca Mevlüt Gürbüz Mechanical Engineering Department Ondokuz Mayıs UniversitySamsun 55169Turkey Mechanical Engineering Department Hitit UniversityÇorum 19169Turkey

The fabrication of boron carbide reinforced aluminum matrix composites(Al-b_(4)C)with various contents of b_(4)C(1wt%,6wt%,15wt%,and 30wt%)was performed by powder metallurgy,and the influence of the content of b_(4)C on their mechanical and tribological behavior was *** Al-30b_(4)C composites recorded the highest density(~2.54 g/cm^(3)),lowest porosity(4%),maximum Vickers hardness(HV~75),lowest weight loss(0.4 mg),and lowest specific wear rate(0.00042 mm^(3)/(N·m))under a load of 7 N,with an enhancement of 167%in hardness,a decrease of 75.8%in weight loss,and a decrease of 76.7%in the specific wear rate compared with pure *** addition,the scanning electron microscope images of the worn surface revealed that the Al-b_(4)C composite has the narrowest wear groove of 0.85 mm at a load of 7 N,and the main wear mechanism was observed as an abrasive wear *** to the friction analysis,the coefficient of friction between surfaces increased with increasing boron carbide content and with decreasing applied *** conclusion,b_(4)C is an effective reinforcement material in terms of tribological and mechanical performance of the Al-b_(4)C composites.

关键词： aluminum boron carbide composite wear friction

Physics package based on intracavity laser cooling ^(87)rb atoms for space cold atom microwave clock

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Chinese Physics b 2024年第7期33卷 22-26页

作者：邓思敏达任伟项静峰赵剑波李琳张迪万金银孟艳玲蒋小军李唐刘亮吕德胜 Aerospace Laser Technology and System Department Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800China Mechanics Chinese Academy of SciencesShanghai 201800China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China

This article proposes a new physics package to enhance the frequency stability of the space cold atom clock with the advantages of a microgravity environment. Clock working processes, including atom cooling, atomic state preparation,microwave interrogation, and transition probability detection, are integrated into the cylindrical microwave cavity to achieve a high-performance and compact physics package for the space cold atom clock. We present the detailed design and ground-test results of the cold atom clock physics package in this article, which demonstrates a frequency stability of 1.2×10^(-􀀀12) τ^(-1/2) with a ramsey linewidth of 12.5 Hz, and a better performance is predicted with a 1 Hz or a narrower ramsey linewidth in microgravity environment. The miniaturized cold atom clock based on intracavity cooling has great potential for achieving space high-precision time-frequency reference in the future.

关键词： atomic clock microgravity microwave cavity space station frequency stability

Major,trace element and Sr-Nd isotope evidence for a sublithospheric mantle source for the Umkondo large igneous province

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Geoscience Frontiers 2024年第1期15卷 263-285页

作者： ben Hayes Lewis D.Ashwal Khulekani b.Khumalo Linda M.Iaccheri School of Geosciences University of the WitwatersrandJohannesburg2050South Africa

The Mesoproterozoic(1.11 Ga)Umkondo large igneous province(LIP)in southern Africa and Antarctica was emplaced in<5 Myr and is dominated by low-Ti tholeiitic doleritic-gabbroic *** is of particular interest because it ... 详细信息

The Mesoproterozoic(1.11 Ga)Umkondo large igneous province(LIP)in southern Africa and Antarctica was emplaced inby low-Ti tholeiitic doleritic-gabbroic *** is of particular interest because it is the least studied LIP in southern Africa with both sublithospheric and lithospheric mantle sources proposed and it coincides with the early assembly of Rodinia,so it has importance in understanding the nature of magmatism and tectonics in and around the Kalahari craton during the *** this study,we compiled a large database of existing(~750)and new(~100)major and trace element data for the Umkondo province,as well as 42 new Sr-Nd isotopic measurements,to provide constraints on its magma sources and geochemical *** element compositional variations in the low-Ti tholeiites are explained by low-pressure(1 kbar)three-phase fractional crystallisation(olivine,clinopyroxene and plagioclase)of a parent magma with~10 wt.%MgO in oxidising conditions(QFM+1).Inverse models show that the low-Ti tholeiitic magmas were derived as residual melts after the crystallization of 12%-33%olivine from primary komatiitic-basaltic magmas(up to~20 wt.%MgO)in equilibrium with mantle olivine(Fo90).Low Sm/Yb and TiO2/Yb-Nb/Yb indicate that the primary magmas were derived by 2%-20%shallow(40-50 km)partial melting of spinel *** Sm/Yb is restricted to dyke swarms and may imply limited magma production from deeper(up to~70 km)garnet lherzolite-like *** low-Ti tholeiites of the Umkondo province are enriched in large ion lithophile elements(rb-Sr-Cs-K)and depleted in high-field strength elements(Zr-Hf-Nb-Ta),indicating the involvement of crustal material and/or the subcontinental lithospheric *** is supported by covariations in Th/Nb,Nb/Yb,Nb/La and Ce/Sm with generally negativeΔ***-Nd isotopes lend support to the notion that the Umkondo magmas were derived from depleted and/or enriched sublithospheric mantle sources and subs

关键词： Umkondo large igneous province Low-Ti magma Continental tholeiites Sublithospheric mantle sources Kalahari craton Rodinia

Debaryomyces hansenii supplementation in low fish meal diets promotes growth,modulates microbiota and enhances intestinal condition in juvenile marine fish

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Journal of Animal Science and biotechnology 2024年第1期15卷 253-276页

作者： Ignasi Sanahuja Alberto Ruiz Joana P.Firmino Felipe E.Reyes-López Juan b.Ortiz-Delgado Eva Vallejos-Vidal Lluis Tort Dariel Tovar-ramírez Isabel M.Cerezo Miguel A.Moriñigo Carmen Sarasquete Enric Gisbert Aquaculture Program Institute of Agrifood Research and Technology(IRTA)La Rapita 43540Spain Centro de biotecnologia Acuicola Universidad de Santiago de ChileSantiagoChile Instituto de Ciencias Marinas de Andalucia(ICMAN-CSIC) Avda.Republica Saharaui no 2Campus Universitario Rio San PedroPuerto RealCadiz 11510Spain Nucleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronomicas Facultad de Medicina Veterinaria y AgronomiaUniversidad de Las AmericasSantiagoChile Department of Cell biology Physiologyand ImmunologyUniversitat Autonoma de BarcelonaBarcelonaSpain Centro de Investigaciones biologicas del Noroeste SC CIBNORLa PazMexico Department of Microbiology Instituto de Biotecnologia Y Desarrollo Azul(IBYDA)Faculty of SciencesUniversity of Malaga29010 MalagaSpain SCbI Bioinformatic UnitUniversity of Malaga29590 MalagaSpain

background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed *** hansenii is a yeast species that can be used as a probiotic in aquaculture due to its capacity to i)promote cell proliferation and differen-tiation,ii)have immunostimulatory effects,iii)modulate gut microbiota,and/or iv)enhance the digestive *** provide inside into the effects of *** on juveniles of gilthead seabream(Sparus aurata)condition,we inte-grated the evaluation of the main key performance indicators coupled with the integrative analysis of the intestine condition,through histological and microbiota state,and its transcriptomic *** After 70 days of a nutritional trial in which a diet with low levels of fishmeal(7%)was supplemented with 1.1%of ***(17.2×10^(5) CFU),an increase of ca.12%in somatic growth was observed together with an improve-ment in feed conversion in fish fed a yeast-supplemented *** terms of intestinal condition,this probiotic modu-lated gut microbiota without affecting the intestine cell organization,whereas an increase in the staining intensity of mucins rich in carboxylated and weakly sulphated glycoconjugates coupled with changes in the affinity for certain lectins were noted in goblet *** in microbiota were characterized by the reduction in abundance of several groups of Proteobacteria,especially those characterized as opportunistic *** microarrays-based transcrip-tomic analysis found 232 differential expressed genes in the anterior-mid intestine of ***,that were mostly related to metabolic,antioxidant,immune,and symbiotic *** dietary administration of *** enhanced somatic growth and improved feed efficiency param-eters,results that were coupled to an improvement of intestinal condition as histochemical and transcriptomic tools *** probiotic ye

关键词： Debaryomyces hansenii Intestine condition Low fish meal diet Microbiota Transcriptomics Yeast probiotic