检索结果-南通市图书馆

The RNA binding protein EHD6 recruits the m^(6)A reader YTH07 and sequesters OsCOL4 mRNA into phase-separated ribonucleoprotein condensates to promote rice flowering

引用

Molecular Plant 2024年第6期17卷 935-954页

作者： Song Cui Peizhe Song Chaolong Wang Saihua Chen benyuan Hao Zhuang Xu Liang Cai Xu Chen Shanshan Zhu Xiangchao Gan Hui Dong Yuan Hu Liang Zhou Haigang hou Yunlu Tian Xi Liu Liangming Chen Shijia Liu Ling Jiang Haiyang Wang Guifang Jia Shirong Zhou Jianmin Wan State Key Laboratory for Crop Genetics&Germplasm Enhancement and Utilization Zhongshan Biological Breeding LaboratoryNational Observation and Research Station of Rice Germplasm ResourcesNanjing Agricultural UniversityNanjing 210095China State Key Laboratory for Crop Gene Resources and breeding Institute of Crop ScienceChinese Academy of Agricultural SciencesBeijing 100081China Synthetic and Functional biomolecules Center Beijing National Laboratory for Molecular SciencesKey Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of EducationCollege of Chemistry and Molecular EngineeringPeking-Tsinghua Center for Life SciencesBeijing Advanced Center of RNA BiologyPeking UniversityBeijingChina Jiangsu Key Laboratory of Crop Genomics and Molecular breeding Agricultural College of Yangzhou UniversityYangzhou 225009China Max Planck Institute for Plant breeding Research Carl-von-Linne´-Weg 1050829 KolnGermany

N6-Methyladenosine(m^(6)A)is one of the most abundant modifications of eukaryotic mRNA,but its comprehensive biological functionality remains further *** this study,we identified and characterized a new flowering-promoting gene,EARLY HEADING DATE6(EHD6),in ***6 encodes an RNA recognition motif(RRM)-containing RNA binding protein that is localized in the non-membranous cytoplasm ribonucleoprotein(RNP)granules and can bind both m^(6)A-modified RNA and unmodified RNA *** found that EHD6 can physically interact with YTH07,a YTH(YT521-b homology)domain-containing m^(6)A *** showed that their interaction enhances the binding of an m^(6)A-modified RNA and triggers relocation of a portion of YTH07 from the cytoplasm into RNP granules through phase-separated *** these condensates,the mRNA of a rice flowering repressor,CONSTANS-like 4(OsCOL4),becomes sequestered,leading to a reduction in its protein abundance and thus accelerated flowering through the Early heading date 1 *** together,these results not only shed new light on the molecular mechanism of efficient m^(6)A recognition by the collaboration between an RNA binding protein and YTH family m^(6)A reader,but also uncover the potential for m^(6)A-mediated translation regulation through phaseseparated ribonucleoprotein condensation in rice.

关键词： N6-methyladenosine m^(6)A EHD6 YTH domain-containing protein phase separation heading date

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于流域底栖动物完整性指数评价延河的水生态健康

引用

应用生态学报 2024年第3期35卷 806-816页

作者：贺瑶孙长顺侯易明胡恩侯湘然冯治远张旭达潘保柱西安理工大学西北旱区生态水利国家重点实验室西安710048 陕西省环境科学研究院西安710069

延河流域位于黄土高原丘陵沟壑区,水土流失严重。流域中下游人类活动干扰强烈导致生态环境脆弱。流域内不同地貌单元(峁梁丘陵沟壑区、峁状丘陵沟壑区、破碎塬区)水土流失状况不同,本研究于2021年4月(春季)和10月(秋季)对流域底栖动物... 详细信息

延河流域位于黄土高原丘陵沟壑区,水土流失严重。流域中下游人类活动干扰强烈导致生态环境脆弱。流域内不同地貌单元(峁梁丘陵沟壑区、峁状丘陵沟壑区、破碎塬区)水土流失状况不同,本研究于2021年4月(春季)和10月(秋季)对流域底栖动物群落进行调查,通过构建底栖动物生物完整性指数(b-IbI)对流域水生态进行健康评价,并探究不同地貌单元对底栖动物生物完整性的影响。共鉴定底栖动物4门73属113种,两季度中水生昆虫均为绝对优势类群。对26个候选指标进行筛选发现:春季b-IbI由优势分类单元个体相对丰度、科级耐污指数(FbI)、捕食者个体相对丰度3个指标构成;秋季b-IbI由蜉蝣目分类单元数、FbI、捕食者个体相对丰度3个指标构成。b-IbI评价结果显示,上游干支流83.3%的采样点处于健康状态,而中下游干支流仅有28.6%的采样点处于健康状态,流域春季健康状况优于秋季。Kruskal-Wallis非参数检验表明,破碎塬区秋季底栖动物密度、物种数和b-IbI均显著低于春季,且在秋季时显著低于峁梁丘陵沟壑区、峁状丘陵沟壑区,丰水期集中降雨导致水土流失加剧是造成这种差异的主要原因。冗余分析结果显示,影响春季底栖动物群落结构的关键因子为大石底质、叶绿素a、氧化还原电位、浊度、电导率、溶解氧,影响秋季群落结构的关键因子为硝态氮、氧化还原电位、pH。

关键词：延河流域水土流失底栖动物完整性指数健康评价地貌单元

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

可生物降解塑料取代传统塑料--对碳排放的影响

引用

Engineering 2024年第1期32卷 152-162页

作者： Guanyi Chen Jianyuan Li Yunan Sun Zhi Wang Gary ALeeke Christian Moretti Zhanjun Cheng Yuan Wang Ning Li Lan Mu Jinyu Li Junyu Tao beibei Yan Li'an hou Interdisciplinary Innovation Lab for Environment and Energy School of Mechanical Engineering&School of Biotechnology and Food ScienceTianjin University of CommerceTianjin 300134China School of Environmental Science and Engineering Tianjin UniversityTianjin 300350China School of Ecology and Environment Tibet UniversityLhasa 850012China Tianjin Key Laboratory of biomass Wastes UtilizationTianjin Engineering Research Center for Organic Wastes Safe Disposal and Energy UtilizationTianjin 300072China School of Chemical Engineering University of BirminghamBirmingham B152TTUK Department of Environmental Systems Science ETH ZürichZürich CH-8092Switzerland

In recent years,a great deal of attention has been focused on the environmental impact of plastics,includ-ing the carbon emissions related to plastics,which has promoted the application of biodegradable *** worldwide have shown high interest in replacing traditional plastics with biodegradable ***,no systematic comparison has been conducted on the carbon emissions of biodegrad-able versus traditional plastic *** study evaluates the carbon emissions of traditional and biodegradable plastic products(bPPs)over four stages and briefly discusses environmental and economic *** scenarios-namely,the traditional method,chemical recycling,industrial composting,and anaerobic digestion-are considered for the disposal of waste bPPs(WbPPs).The analysis takes China as a case *** results show that the carbon emissions of 1000traditional plastic products(plastic bags,lunch boxes,cups,etc.)were52.09-150.36 carbon emissions equivalent of per kilogram(kg CO_(2)eq),with the stage of plastic production contributing 50.71%-50.77%.In comparison,1000 similar bPPs topped out at 21.06-56.86 kg CO_(2)eq,approximately 13.53%-62.19%lower than traditional plastic *** difference was mainly at the stages of plastic production and waste disposal,and the bPPs showed significant carbon reduction potential at the raw material acquisition *** disposal plays an important role in environmental impact,and composting and anaerobic digestion are considered to be preferable disposal methods for ***,the high cost of biodegradable plastics is a challenge for their widespread *** study has important reference significance for the sustainable development of the biodegradableplastics industry.

关键词： Carbon emissions biodegradable plastics Different disposal scenarios Daily life consumption Environmental and economic discussion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator

引用

Food Science and Human Wellness 2024年第5期13卷 2917-2936页

作者： Peng Ma Jie Xiao biyu hou Ping He Xinyu Yang Yisa Wang Zijing Wang Tianshu Xu Xiuying Yang Xuan Zhu Shasha Xiang Song Li Guanhua Du Jian Ying Guifen Qiang State Key Laboratory of bioactive Substance and Function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical College and Beijing Key Laboratory of Drug Target and Screening ResearchBeijing 100050China COFCO Nutrition and Health Research Institute Beijing 102209China Department of Pharmacy The Eighth Affiliated HospitalSun Yat-sen UniversityShenzhen 518000China Faculty of biology Medicine and Health SciencesThe University of ManchesterManchester M139PLUnited Kingdom Changchun University of Chinese Medicine Changchun 130117China School of Food Science and biotechnology Zhejiang Gongshang UniversityHangzhou 310018China China Tea Technology(beijing)Co. Ltd.Beijing 102209China beijing Key Laboratory of Nutrition Health and Food SafetyBeijing 102209China

Obesity is a metabolic disorder due to over-accumulation of adipose tissue and ultimately becomes a“disease”.brown adipose tissue(bAT)thermogenesis and white adipose tissue(WAT)browning emerge as a potential strategy of anti-obesity by dissipating energy as ***,drugs based on adipose tissue thermogenesis have not been successfully approved *** current study,we found that black tea extract(bTE)obtained by patentauthorized manufacturing process prevented body weight gain as novel thermogenic activator with reduction of adiposity,improvement of adipose distribution,and glucose metabolism improvement in diet-induced obesity ***,anti-obesity effect of bTE depends on promoting bAT thermogenesis and WAT browning with upregulation of uncoupling protein 1(UCP1),especially visceral adipose tissue(VAT)with browning ***,utilizing in silico approach of network pharmacology and molecular docking,we identified carbonic anhydrase 2(CA2)in nitrogen metabolism as anti-obesity target of bTE and further elucidated that protein kinase b(AKT)signaling pathway linked CA2 and *** gut microbiota regulation may prompt the CA2-dependent thermogenesis *** findings demonstrated anti-obesity effect of bTE as thermogenic activator through CA2-mediated bAT thermogenesis and WAT browning via CA2-AKT-UCP1 signaling pathway,which could be developed as promising anti-obesity agent with good safety and efficacy.

关键词： Obesity black tea Thermogenesis browning Adipose tissue

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

南水北调中线工程通水对沿线地区经济增长的影响——基于受水区和水源地的检验

引用

长江流域资源与环境 2024年第6期33卷 1168-1181页

作者：李祎雯侯瑞雪王莹河海大学商学院江苏南京210000

水资源配置深刻影响着地区经济发展格局。南水北调工程为优化水资源配置、缓解我国北方地区水资源严重短缺问题提供有力支撑,但工程运行通水能否进一步推动受水区和水源地经济增长呢?以南水北调中线工程为例,运用合成控制法,分析工程运... 详细信息

水资源配置深刻影响着地区经济发展格局。南水北调工程为优化水资源配置、缓解我国北方地区水资源严重短缺问题提供有力支撑,但工程运行通水能否进一步推动受水区和水源地经济增长呢?以南水北调中线工程为例,运用合成控制法,分析工程运行通水对受水地区以及水源地区经济增长的影响,并检验其中的作用机制。研究表明:(1)从整体效应来看,中线工程通水显著提高了受水区和水源地的人均GDP和夜间灯光亮度,说明工程通水有效促进了两地区经济增长量和经济活跃度的提升。就动态效应来看,工程通水对受水区经济增长的促进作用存在一定滞后性,通水后的前两年对水源地经济发展产生微弱冲击,此后呈现正向促进作用。(2)中线工程通水运行对受水区和水源地产业结构合理化均产生显著正向影响,产业结构合理化程度的加深进一步促进两地区经济增长。(3)中线工程通水提升了受水区产业结构高级化程度,但对水源区产业结构高级化的影响存在一定滞后性;工程通水运行所带来的产业结构高级化效应能够显著促进两地区经济增长。(4)从经济增长的不同维度来看,受水区和水源区人均经济量的增长主要依赖于工程通水所产生的产业结构合理化效应;而经济活跃度的提升则依赖于产业结构高级化效应。最后,对推进南水北调后续工程高质量发展,充分发挥工程战略性、基础性功能提出政策建议。

关键词：南水北调中线工程区域经济增长合成控制法产业结构升级

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

空位扩散诱导点缺陷环与富Cu相的相互作用

引用

稀有金属材料与工程 2024年第3期53卷 834-840页

作者：裴嘉琪侯华杨文奎赵宇宏中北大学山西太原030051 教育部共建高性能铝/镁合金材料开发及应用协同创新中心山西太原030051 北京科技大学北京市材料基因工程高精尖创新中心北京100083 太原科技大学山西太原030024

辐照诱导产生的点缺陷会加速核电站材料微观组织的演变,在很大程度上影响反应堆的寿命。本研究基于相场法的四元连续相场模型,耦合了空位和间隙原子,利用该模型模拟了Fe-15%Cu-1%Ni-1%Mn(原子分数)合金在空位扩散机制下的相分离,研究了... 详细信息

辐照诱导产生的点缺陷会加速核电站材料微观组织的演变,在很大程度上影响反应堆的寿命。本研究基于相场法的四元连续相场模型,耦合了空位和间隙原子,利用该模型模拟了Fe-15%Cu-1%Ni-1%Mn(原子分数)合金在空位扩散机制下的相分离,研究了点缺陷与富Cu相的相互作用机制。结果表明,空位和间隙原子会促进富Cu相的长大和粗化,点缺陷浓度的升高会促进相分离,加快析出相的失稳分解速率,并且升高温度会延缓Cu原子和空位环的生长和粗化,点缺陷也可以增加一定的屈服强度,为探究空位扩散机制影响抗辐照材料性能方面提供了新的思路。

关键词：相场法点缺陷富Cu析出相空位间隙原子

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Pb、Zn和Cd复合重金属潜在超富集植物的筛选与胁迫响应特征

引用

环境科学 2024年第8期45卷 4870-4882页

作者：范拴喜张楠孙旻涵侯宪东陕西地建西安交大土地工程与人居环境技术创新中心西安710049 宝鸡文理学院地理与环境学院宝鸡721013 陕西省灾害监测与机理模拟重点实验室宝鸡721013

为了筛选Pb、Zn和Cd复合重金属超富集植物,对宝鸡市典型铅锌矿和冶炼厂区优势植物进行调查、采样和分析,初步筛选出一种潜在的Pb、Zn和Cd复合重金属超富集植物,并采用土培盆栽试验观测其在Pb、Zn和Cd复合重金属胁迫下叶绿素(叶绿素a、... 详细信息

为了筛选Pb、Zn和Cd复合重金属超富集植物,对宝鸡市典型铅锌矿和冶炼厂区优势植物进行调查、采样和分析,初步筛选出一种潜在的Pb、Zn和Cd复合重金属超富集植物,并采用土培盆栽试验观测其在Pb、Zn和Cd复合重金属胁迫下叶绿素(叶绿素a、叶绿素b、类胡萝卜素、总叶绿素)、抗氧化酶(SOD、CAT、POD)和其他生理指标(MDA、脯氨酸)的响应特征,再通过大田试验,进一步验证并确定了其对Pb、Zn和Cd复合重金属的富集能力,以期为Pb、Zn和Cd复合重金属污染土壤修复提供科学依据和技术支撑.结果表明,野外调查发现聚合草对Pb、Zn和Cd的富集量、富集系数(bCF)和转移系数(TF)均满足国际上超富集植物指标限值要求,是一种潜在的Pb、Zn和Cd复合重金属超富集植物;土培盆栽试验显示,随着Pb、Zn和Cd复合重金属胁迫梯度的提高,聚合草叶片中叶绿素a、叶绿素b和总叶绿素含量逐渐降低,直至胁迫梯度大于等于Ⅳ时,导致植物光合系统紊乱;蓖麻叶片中的叶绿素含量呈现“低促高抑”现象,而胁迫过高则激发了自身其他保护系统使得毒害减轻而升高;另外,与CK相比,聚合草和蓖麻的叶绿素a、叶绿素b、类胡萝卜素和总叶绿素各自均存在显著性差异(Pb、Zn和Cd的富集量、bCF和TF均可以达到超富集植物指标限值要求,是一种潜在的Pb、Zn和Cd复合重金属超富集植物种质资源,能作为Pb、Zn和Cd复合重金属污染土壤修复的优选植物.

关键词： Pb、Zn和Cd复合污染超富集植物生理特性植物修复聚合草蓖麻

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

肝血管内大b细胞淋巴瘤1例

引用

中华病理学杂志 2024年第10期53卷 1042-1044页

作者：杨洁真侯英勇葛晓雯复旦大学附属中山医院厦门医院病理科厦门361015 复旦大学附属中山医院病理科上海200032

患者男,69岁。主要症状为腹痛和发热。腹部磁共振成像检查显示肝左叶异常信号,初步考虑肝脓肿或肝内胆管癌。穿刺肝组织镜下9个汇管区均见炎性细胞浸润,汇管区血管内见异型淋巴细胞增生,细胞体积大,空泡状核,核仁明显,核分裂象易见,呈... 详细信息

患者男,69岁。主要症状为腹痛和发热。腹部磁共振成像检查显示肝左叶异常信号,初步考虑肝脓肿或肝内胆管癌。穿刺肝组织镜下9个汇管区均见炎性细胞浸润,汇管区血管内见异型淋巴细胞增生,细胞体积大,空泡状核,核仁明显,核分裂象易见,呈非肝血窦内生长模式。免疫组织化学结果示肿瘤细胞位于血管腔内,并表达CD20等b淋巴细胞标志物。b淋巴细胞基因克隆性重排阳性。肝脏血管内大b细胞淋巴瘤呈非肝窦内生长模式病例罕见,易被漏诊或误诊,诊断时需与反应性炎症、转移性低分化癌或上皮样血管内皮瘤等鉴别。确诊需要依赖于组织形态学、免疫组织化学和基因重排等多方面的综合分析。

关键词：异型淋巴细胞上皮样血管内皮瘤汇管区肝内胆管癌肝左叶肝脓肿低分化癌免疫组织化学

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Disorder-to-order transition induced by spontaneous cooling regulation in robotic active matter

引用

Chinese Physics b 2024年第7期33卷 96-103页

作者：侯帅旭王高马星宇汪楚云王鹏陈怀城刘雳宇王璟 Chongqing Key Laboratory of Soft Condensed Matter Physics and Smart Materials College of PhysicsChongqing UniversityChongqing 401331China Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325011China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China School of Ophthalmology and Optometry Eye HospitalSchool of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325035China Postgraduate Training base Alliance Wenzhou Medical UniversityWenzhou 325035China

In classical matter systems, typical phase-transition phenomena usually stem from changes in state variables, such as temperature and pressure, induced by external regulations such as heat transfer and volume adjustment. However, in active matter systems, the self-propulsion nature of active particles endows the systems with the ability to induce unique collectivestate transitions by spontaneously regulating individual properties to alter the overall states. based on an innovative robot-swarm experimental system, we demonstrate a field-driven active matter model capable of modulating individual motion behaviors through interaction with a recoverable environmental resource field by the resource perception and *** the simulated model, by gradually reducing the individual resource-conversion coefficient over time, this robotic active matter can spontaneously decrease the overall level of motion, thereby actively achieving a regulation behavior like the cooling-down control. Through simulation calculations, we discover that the spatial structures of this robotic active matter convert from disorder to order during this process, with the resulting ordered structures exhibiting a high self-adaptability on the geometry of the environmental boundaries.

关键词： active matter robot swarm collective-state transitions environmental self-adaptability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Revisit of the anisotropic vortex states of 2H-NbSe_(2) towards the zero-field limit

引用

Chinese Physics b 2024年第6期33卷 80-86页

作者：张凡侯兴元姜宇轩张宗源涂玉兵朱相德陈根富单磊 beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100190China Center of Free Electron Laser and High Magnetic Field Anhui UniversityHefei 230601China Information Materials and Intelligent Sensing Laboratory of Anhui Province Institutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601China Key Laboratory of Structure and Functional Regulation of Hybrid Materials in Anhui University Ministry of EducationHefei 230601China School of Physics and Materials Science Anhui UniversityHefei 230601China Anhui Key Laboratory of Condensed Matter Physics at Extreme Conditions High Magnetic Field LaboratoryHFIPSAnhuiChinese Academy of Sciencesand University of Science and Technology of ChinaHefei 230031China Hefei National Laboratory Hefei 230088China

We revisited the vortex states of 2H-NbSe_(2) towards zero fields by a low-temperature scanning tunneling *** structures of the anisotropic vortex states were distinguished, one is a spatially non-splitting zero bias peak, and the other is an in-gap conductance anomaly resembling evolved crossing features around the center of the three nearest *** of them distribute solely along the next nearest neighboring direction of the vortex lattice and become unresolved in much higher magnetic fields, implying an important role played by the vortex–vortex interactions. To clarify these issues,we have studied the intrinsic vortex states of the isolated trapped vortex in zero fields at 0.45 K. It is concluded that the anisotropic zero bias peak is attributed to the superconducting gap anisotropy, and the spatially evolved crossing features are related to the vortex–vortex interaction. The vortex core size under the zero-field limit is determined. These results provide a paradigm for studying the inherent vortex states of type-II superconductors especially based on an isolated vortex.

关键词： vortex states zero-bias conductance peak scanning tunneling microscopy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：