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Applied Mathematics and Mechanics(English Edition) 2023年第4期44卷 653-668页

作者： b.J.GIREESHA M.l.KEERTHI Department of PG Studies and Research in Mathematics Kuvempu UniversityShankaraghatta 577451India

A moving trapezoidal profiled convective-radiative porous longitudinal fin wetted in a single-phase fluid is considered in the current *** periodic variation in the fin base temperature is taken into account along with the temperature sensitive thermal conductivity and convective heat transfer *** modeled problem,which is resolved into a non-linear partial differential equation(PDE),is made dimensionless and solved by employing the finite difference method(FDM).The results are displayed through graphs and *** effects of amplitude,frequency of oscillation,wet nature,Peclet number,and other relevant quantities on the distribution of temperature through the fin length and with the dimensionless time are *** is deciphered that the periodic heat transfer gives rise to the wavy nature of the fin thermal profile against *** analysis is beneficial in the design of fin structures for applications like solar collectors,space/airborne applications,and refrigeration industries.

关键词： convection fully wet porous fin trapezoidal profile moving fin unsteady periodic thermal condition

Fibrosing cholestatic hepatitis following cytotoxic chemotherapy for small-cell lung cancer

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World Journal of Gastroenterology 2009年第18期15卷 2290-2292页

作者： Jaime Ceb.llos-Viro José M lópez-Picazo José l Pérez-Gracia Jesús J Sola Gregorio Aisa Ignacio Gil-bazo Department of Oncology Clínica Universidad de NavarraPio XII 3631008 PamplonaSpain Department of Pathology Clínica Universidad de NavarraPio XII 3631008 PamplonaSpain

Fibrosing cholestatic hepatitis(FCH) is a variant of viral hepatitis reported in hepatitis b virus or hepatitis C virus infected liver,renal or bone transplantation recipients and in leukemia and lymphoma patients after conventional cytotoxic *** constitutes a well-described form of fulminant hepatitis having extensive fibrosis and severe cholestasis as its most characteristic pathological ***,we report a case of a 49-year-old patient diagnosed with small-cell lung cancer who developed this condition following conventional chemotherapy-induced *** is the first reported case in the literature of FCH after conventional chemotherapy for a solid *** addition to a detailed report of the case,a physiopathological examination of this potentially life-threatening condition and its treatment options are discussed.

关键词： Fibrosing cholestatic hepatitis Immunosuppression Chemotherapy lung cancer Hepatitis bvirus lamivudine

black hole shadows in Einstein-b.l-Robinson gravity

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Chinese Physics C 2024年第5期48卷 272-283页

作者： b.Hamil b.C.lütfüoğlu laboratoire de Physique Mathématique et Subatomique Facultédes Sciences ExactesUniversitéConstantine 1ConstantineAlgeria Department of Physics University of Hradec KrálovéRokitanského 6250003 Hradec KrálovéCzechia

Gravity models given by higher-order scalar curvature corrections are b.lieved to bear important consequences. Einstein-b.l-Robinson (EbR) gravity with quartic curvature modification motivated Sajadi et al. to explore static spherically symmetric black hole solutions using perturbative methods. In this study, inspired by their work, we investigate AdS black hole shadows in EbR gravity and demonstrate how the gravity parameter alters the energy emission rate. Finally, we address the same problem in the presence of plasma, because the black holes are thought to be surrounded by a medium that changes the geodesic of photons.

关键词： black hole shadows Einstein-b.l-Robinson gravity plasma

Combined Effects of Different Overload Ratios and Nitriding Process on Fatigue Crack Growth of AISI 4140 Steel

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Journal of Iron and Steel Research International 2014年第8期21卷 797-803页

作者： A.b.Sengül A.elik Department of Mechanical Engineering anakkale Onsekiz Mart University Department of Mechanical Engineering Ataturk University

The combined effects of different overload ratios（OlRs）and nitriding process on fatigue crack growth（FCG）were *** compact tension specimens made of AISI 4140 steel were subjected to the plasma nitrification process using agas mixture of 50% N2 and 50% H2 at 500℃for *** properties of the samples were studied by scanning electron microscopy,optical microscopy,microhardness testing and digital *** nitriding slowed down FCG,but the crack growth retardation caused by the overload was reduced when the OlR was 2.0and *** did not take effect when the OlR was 1.5and 3.0.

关键词： fatigue crack growth plasma nitriding overload ratio retardation digital image correlation

Treatment of inflammatory bowel disease:A review of medical therapy

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World Journal of Gastroenterology 2008年第3期14卷 354-377页

作者： Patricia l Kozuch Stephen b Hanauer Division of Gastroenterology and Hepatology Department of Medicine Thomas Jefferson University Hospital Philadelphia PA United States University of Chicago Hospitals Department of Medicine Section of Gastroenterology and Nutrition Chicago IL 60637 United States

Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory diseases of the gastrointestinal tract. While a cure remains elusive, both can be treated with medications that induce and maintain remission. With the recent advent of therapies that inhibit tumor necrosis factor (TNF) alpha the overlap in medical therapies for UC and CD has become greater. Although 5-ASA agents have been a mainstay in the treatment of both CD and UC, the data for their efficacy in patients with CD, particularly as maintenance therapy, are equivocal. Antibiotics may have a limited role in the treatment of colonic CD. Steroids continue to be the first choice to treat active disease not responsive to other more conservative therapy; non- systemic steroids such as oral and rectal budesonide for ileal and right-sided CD and distal UC respectively are also effective in mild-moderate disease. 6-mercaptopurine (6-MP) and its prodrug azathioprine are steroid-sparing immunomodulators effective in the maintenance of remission of both CD and UC, while methotrexate may be used in both induction and maintenance of CD. Infliximab and adalimumab are anti-TNF agents approved in the US and Europe for the treatment of Crohn's disease, and infliximab is also approved for the treatment of UC.

关键词： Inflammatory bowel disease Crohn's disease Ulcerative colitis Medical therapy

Immunotherapy and therapeutic vaccines in prostate cancer： an update on current strategies and clinical implications

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Asian Journal of Andrology 2014年第3期16卷 364-371页

作者： b Harpreet Singh James l Gulley Medical Oncology branch Center for Cancer Research National Cancer Institute National Institutes of Health 10 Center Drive Bethesda Maryland USA

In recent years, immunotherapy has emerged as a viable and attractive strategy for the treatment of prostate cancer. While there are multiple ways to target the immune system, therapeutic cancer vaccines and immune checkpoint inhibitors have been most successful in late-stage clinical trials. The landmark Food and Drug Administration approval of sipuleuceI-T for asymptomatic or minimally symptomatic metastatic prostate cancer set the stage for ongoing phase III trials with the cancer vaccine PSA-TRICOM and the immune checkpoint inhibitor ipilimumab. A common feature of these immune-based therapies is the appearance of improved overall survival without short-term changes in disease progression. This class effect appears to be due to modulation of tumor growth rate kinetics, in which the activated immune system exerts constant immunologic pressure that slows net tumor growth. Emerging data suggest that the ideal population for clinical trials of cancer vaccines is patients with lower tumor volume and less aggressive disease. Combination strategies that combine immunotherapy with standard therapies have been shown to augment both immune response and clinical benefit.

关键词： androgen deprivation immunotherapy prostate cancer therapeutic cancer vaccines

在同样结构尺寸下具有较高推力的F100—PW—229发动机

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航空发动机参考资料 1989年第2期 1-11页

作者： Koff,b.l 马海舟

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina Hromada Patrick Heimel Markus Kerbl lászlóGál Sylvia Nürnberger barbara Schaedl James Ferguson Nicole Swiadek Xavier Monforte Johannes C.Heinzel Antal Nógrádi Andreas H.Teuschl-Woller David Hercher Department life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria ludwig b.ltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of Hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availab.lity of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tub.lar nerve guidance conduits(tNGCs). However, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tub.lar walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tub.lar walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

A Search on Dirac Equation

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Chinese Physics letters 2007年第11期24卷 3024-3027页

作者： M. Kocak, b. Gonül Department of Engineering Physics Faculty of Engineering University of Gaziantep 27310 Gaziantep Turkey

The solutions, in terms of orthogonal polynomials, of Dirac equation with analytically solvable potentials are investigated within a novel formalism by transforming the relativistic equation into a Schrodinger-like one. Earlier results are discussed in a unified framework, and some solutions of a large class of potentials are given.

关键词： coated conductor buffer layer self-epitaxy CeO2

Remarks on Exact Solvab.lity of Quantum Systems with Spatially Varying Effective Mass

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Chinese Physics letters 2005年第11期22卷 2742-2745页

作者： b. Goenül M. Kocak Department of Engineering Physics Faculty of Engineering University of Gaziantep 27310 Gaziantep Türkiye

Within the frame of a novel treatment we make a complete mathematical analysis of exactly solvable onedimensional quantum systems with non-constant mass, involving their ordering ambiguities. This work extends the results recently reported in the literature and clarifies the relation between physically acceptable effective mass Hamiltonians.

关键词： DEPENDENT EFFECTIVE MASSES SUPERSYMMETRIC APPROACH SCHRODINGER-EQUATION PERTURbATION-THEORY POTENTIAlS SEMICONDUCTORS STATES