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FDNet: Fourier transform guided dual-channel underwater image enhancement diffusion network

Science China Technological Sciences 2025年第1期 62-78页

作者： zhen Zhu Xiaobo Li Qianwen MA Jingsheng ZHAi Haofeng hu School of Marine Science and Technology Tianjin University College of Mechanical Engineering and Automation Fuzhou University

Due to the scattering and absorption of light, underwater imaging yields suboptimal results characterized by low b.ightness, diminished image contrast, and the loss of details. Current learning-based underwater image enhancement(UiE)methods mainly focus on addressing these issues in the spatial domain, with limited attention to the Fourier frequency *** propose the Fourier transform guided dual-channel underwater image enhancement diffusion network(FDNet), aiming to fully leverage frequency domain information and the characteristics of a diffusion-based generation model. The amplitude-phase dualchannel not only effectively provides feedback on the energy distribution of the image but also incorporates crucial image structure and texture information. Capitalizing on these advantages, we first introduce a Fourier transform-based amplitude-phase dualchannel enhancement front-end network for UiE. This network significantly improves the quality of the network's image input,including b.ightness and contrast, by incorporating phase congruency edge enhancement and prior-driven amplitude mapping strategies. The preceding network mitigates the overall training challenges caused by poor input image quality. Simultaneously,the application of denoising networks based on lightweight transformers effectively improves the computational time required for each iteration during model training. The results indicate that FDNet outperforms many current learning-based UiE algorithms in restoring images across multiple real underwater image datasets, demonstrating more robust generalization capabilities in degraded underwater scenarios. The competitive performance advantage achieved in enhancing visual quality underscores the effectiveness of our method.

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brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing Chen Shuyuan b.i Qiong Wu Yushan Chen zhen Wei Yufei Mei Yan Zeng brain Science and Advanced Technology institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Pub.ic Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase b signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,bDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

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Liver as a new target organ in Alzheimer's disease:insight from cholesterol metabolism and its role in amyloid-beta clearance

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Neural Regeneration Research 2025年第3期20卷 695-714页

作者： b.ib.i Wu Yuqing Liu Hongli Li Lemei Zhu Lingfeng Zeng zhen Zhang Weijun Peng Department of integrated Traditional Chinese&Western Medicine The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Academician Workstation Changsha Medical UniversityChangshaHunan ProvinceChina Yangsheng College of Traditional Chinese Medicine Guizhou University of Traditional Chinese MedicineGuiyangGuizhou ProvinceChina Qinhuangdao Shanhaiguan Pharmaceutical Co. LtdQinhuangdaoHebei ProvinceChina National Clinical Research Center for Mental Disorder The Second Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Alzheimer's disease,the primary cause of dementia,is characterized by neuropathologies,such as amyloid plaques,synaptic and neuronal degeneration,and neurofib.illary *** amyloid plaques are the primary characteristic of Alzheimer's disease in the central nervous system and peripheral organs,targeting amyloid-beta clearance in the central nervous system has shown limited clinical efficacy in Alzheimer's disease *** abnormalities are commonly observed in patients with Alzheimer's *** liver is the primary peripheral organ involved in amyloid-beta metabolism,playing a crucial role in the pathophysiology of Alzheimer's ***,impaired cholesterol metabolism in the liver may exacerbate the development of Alzheimer's *** this review,we explore the underlying causes of Alzheimer's disease and elucidate the role of the liver in amyloid-beta clearance and cholesterol ***,we propose that restoring normal cholesterol metabolism in the liver could represent a promising therapeutic strategy for addressing Alzheimer's disease.

关键词： AbCA1 Alzheimer's disease amyloid-beta apolipoprotein E cholesterol metabolism liver liver X receptor low-density lipoprotein receptor-related protein 1 peripheral clearance tauroursodeoxycholic acid

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SensFL:Privacy-Preserving Vertical Federated Learning with Sensitive Regularization

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 385-404页

作者： Chongzhen Zhang Zhichen Liu Xiangrui Xu Fuqiang hu Jiao Dai b.igen Cai Wei Wang School of Automation and intelligence Beijing Jiaotong UniversityBeijing100044China Shuohuang Railway Development Co. Ltd.National Energy GroupCangzhou062350China b.ijing Key Laboratory of Security and Privacy in intelligent Transportation School of Computer Science and TechnologyBeijing Jiaotong UniversityBeijing100044China

in the realm of intelligent Railway Transportation Systems,effective multi-party collaboration is crucial due to concerns over privacy and data *** Federated Learning(VFL)has emerged as a promising approach to facilitate such collaboration,allowing diverse entities to collectively enhance machine learning models without the need to share sensitive training ***,existing works have highlighted VFL’s susceptibility to privacy inference attacks,where an honest but curious server could potentially reconstruct a client’s raw data from embeddings uploaded by the *** vulnerability poses a significant threat to VFL-based intelligent railway transportation *** this paper,we introduce SensFL,a novel privacy-enhancing method to against privacy inference attacks in ***,SensFL integrates regularization of the sensitivity of embeddings to the original data into the model training process,effectively limiting the information contained in shared *** reducing the sensitivity of embeddings to the original data,SensFL can effectively resist reverse privacy attacks and prevent the reconstruction of the original data from the *** experiments were conducted on four distinct datasets and three different models to demonstrate the efficacy of *** results show that SensFL can effectively mitigate privacy inference attacks while maintaining the accuracy of the primary learning *** results underscore SensFL’s potential to advance privacy protection technologies within VFL-based intelligent railway systems,addressing critical security concerns in collaborative learning environments.

关键词： Vertical federated learning privacy defenses

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Characteristic changes in astrocyte properties during astrocyte-to-neuron conversion induced by NeuroD1/Ascl1/Dlx2

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Neural Regeneration Research 2025年第6期20卷 1801-1815页

作者： Qing He zhen Wang Yuchen Wang Mengjie Zhu Zhile Liang Kanghong Zhang Yuge Xu Gong Chen GHM institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina

Direct in vivo conversion of astrocytes into functional new neurons induced by neural transcription factors has been recognized as a potential new therapeutic intervention for neural injury and degenerative disorders. However, a few recent studies have claimed that neural transcription factors cannot convert astrocytes into neurons, attributing the converted neurons to pre-existing neurons mis-expressing transgenes. in this study, we overexpressed three distinct neural transcription factors––NeuroD1, Ascl1, and Dlx2––in reactive astrocytes in mouse cortices subjected to stab.injury, resulting in a series of significant changes in astrocyte properties. initially, the three neural transcription factors were exclusively expressed in the nuclei of astrocytes. Over time, however, these astrocytes gradually adopted neuronal morphology, and the neural transcription factors was gradually observed in the nuclei of neuron-like cells instead of astrocytes. Furthermore,we noted that transcription factor-infected astrocytes showed a progressive decrease in the expression of astrocytic markers AQP4(astrocyte endfeet signal), CX43(gap junction signal), and S100β. importantly, none of these changes could be attributed to transgene leakage into preexisting neurons. Therefore, our findings suggest that neural transcription factors such as NeuroD1, Ascl1, and Dlx2 can effectively convert reactive astrocytes into neurons in the adult mammalian brain.

关键词： aquaporin-4 Ascl1 astrocyte cortex Dlx2 gap junction glia-to-neuron conversion neural regeneration NeuroD1 reprogramming

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A novel phenomenological model using a sine function for finite-element simulation of large-strain hot deformation

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Science China(Technological Sciences) 2018年第5期61卷 748-760页

作者： ZENG Fan hu ChengLiang ZHAO zhen institute of Forming Technology & Equipment Shanghai Jiao Tong University

in hot deformation, the flow stress curves of steels always present as two typical types: at relatively high temperature and low strain rate, the flow stress may first increase and then attain a steady value without reaching an ob.ious peak stress; in other situations, the flow stress decreases after reaching peak stress and then attains a steady value. A new phenomenological model,described by a sine-function equation, is proposed to define the relationship between flow stress and deformation parameters. A series of isothermal compressions for a carbon steel were carried out, as a case study, to obtain basic experimental *** of the new model were sequentially determined. The predicted results of the proposed model were compared with actual measured data. Good accuracy was found in the standard statistical parameters of correlation coefficient, root mean square error, and average absolute relative error with the values of 0.935, 7.137 MPa and 4.352%, respectively. Discussion of applications of different models in finite-element simulation demonstrated the benefit of the new model. When comparing the simulation results of three different deformation patterns with large strain, the new model showed 10%–20% lower predicted forming load than the original Arrhenius equation, and better applicability and reliability than modified Arrhenius equations.

关键词： phenomenological model high temperature large strain finite-element simulation

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"Clean"doping to advance 2D material phototransistors

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Light(Science & Applications) 2022年第7期11卷 1322-1323页

作者： zhen Wang Peng Wang Weida hu State Key Laboratory of infrared Physics Shanghai Institute of Technical PhysicsChinese Academy of Sciences200083ShanghaiChina

Doping is an essential element to develop next-generation electronic and optoelectronic devices and has to break the limit of specific steps during material synthesis and device *** the authors reveal“clean”doping to enhance the electric and photoelectric performance of two-dimensional(2D)indium selenide(inSe)via a neutron-transmutation method for the first time,even after device fab.ication.

关键词： optoelectronic doping Clean

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Fe、ir掺杂MoS_(2)表面对N_(2)气敏吸附与解离反应性能提升的第一性原理研究

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原子与分子物理学报 2025年第1期42卷 13-19页

作者：肖香珍胡林峰张建伟河南科技学院新乡453003

基于第一性原理方法,采用周期性平板模型,研究了N_(2)分子在掺杂体系TM-MoS_(2)(TM=Fe、ir)表面的吸附和解离行为.研究表明:N_(2)分子在TM-MoS_(2)(TM=Fe、ir)表面吸附能依次为0.62和0.47 eV,而完整MoS_(2)表面的吸附能只有0.08 eV,说... 详细信息

基于第一性原理方法,采用周期性平板模型,研究了N_(2)分子在掺杂体系TM-MoS_(2)(TM=Fe、ir)表面的吸附和解离行为.研究表明:N_(2)分子在TM-MoS_(2)(TM=Fe、ir)表面吸附能依次为0.62和0.47 eV,而完整MoS_(2)表面的吸附能只有0.08 eV,说明掺杂之后对N_(2)表现出略好的吸附性能.差分电荷密度分析表明,N_(2)吸附后,掺杂Fe、ir原子与两个N原子之间电荷有所增加,N-N键之间的区域电荷密度减少,N-N键的强度减弱.态密度计算结果发现,N_(2)在吸附过程中,主要是N原子的2p_(y)、2p_(z)轨道与ir的5d_(xy)和5d_(z^(2))以及Fe的3d_(xy)和3d_(z^(2))发生杂化作用.通过分析解离活化能,N_(2)在掺杂体系TM-MoS_(2)(TM=Fe、ir)表面解离需要活化能均较高,且远大于在相应掺杂表面的吸附能,说明N_(2)在掺杂体系TM-MoS_(2)(TM=Fe、ir)表面解离应该表现为分子吸附或脱附.

关键词： Fe、ir 掺杂单层MoS_(2) N_(2) 吸附与解离活化能密度泛函理论

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EbSD parameter assessment and constitutive models of crept HR3C austenitic steel

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Journal of iron and Steel Research international 2023年第4期30卷 772-781页

作者： Jie Zhang zheng-fei hu zhen Zhang Shanghai Key Laboratory for R&D and Application of Metallic Functional Materials School of Materials Science and EngineeringTongji UniversityShanghai 201804China School of Materials Science and Engineering Nanjing Institute of TechnologyNanjing 211167JiangsuChina

Creep damage and evolution of HR3C steel at 650℃ were investigated using electron backscatter diffraction(EbSD),and EbSD-based parameter assessments were *** analyses show that the grain size is almost unchanged and no ob.ious texture formed after creep at different creep *** lowest proportion of low Σ coincidence site lattice grain boundaries under 150 MPa implies that the primary twin structures are preserved under the low stress level,while some twin structures evolved into general grain boundaries at the high creep *** main damage features of microcracks and cavities can be seen along the grain boundaries:the former emerged at higher stress levels,while the latter appeared at the lower stress level,and both were shown under medium *** contrast shows that the most severe creep damage is present at 170 *** implies that the creep mechanism differs distinctly under different stress levels,and the transition point is around 170 *** average misorientation is better to describe the local plastic deformation related to the strain distribution while grain reference orientation deviation describes the inhomogeneous strain *** lifetime prediction models including the isothermal method,Larson-Miller parameter method and Monkman–Grant relation were evaluated by the experimental data and literature data,and they are valid for predicting creep behavior.

关键词： Austenitic heat-resistant steel Creep damage Electron backscatter diffraction Creep constitutive model Creep lifetime prediction

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Construction of a bacterial Artificial Chromosome Library of TM-1,a Standard Line for Genetics and Genomics in Upland Cotton

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Journal of integrative Plant biology 2009年第1期51卷 107-112页

作者： Yan hu Wang-zhen Guo Tian-zhen Zhang National Key Laboratory of Crop Genetics & Germplasm Enhancement Cotton Research Institute Nanjing Agricultural University Nanjing 210095 China

A bacterial artificial chromosome （bAC） library was constructed for Gossypium hirsutum acc. TM-1, a genetic and genomic standard line for Upland cotton. The library consists of 147 456 clones with an average insert size of 122.8 kb ranging from 97 to 240 kb. About 96.0% of the clones have inserts over 100 kb. Therefore, this library represents theoretically 7.4 haploid genome equivalents based on an AD genome size of 2 425 Mb. Clones were stored in 384 384- well plates and arrayed into multiplex pools for rapid and reliable library screening. bAC screening was carried out by four-round poiymerase chain reactions using 23 simple sequence repeats （SSR） markers, three sequence-related amplified polymorphism markers and one pair of primers for a gene associated with fiber development to test the quality of the library. Correspondingly, in total 92 positive bAC clones were identified with an average four positive clones per SSR marker, ranging from one to eight hits. Additionally, since these SSR markers have been localized to chromosome 12 （A12） and 26 （D12） according to the genetic map, these bAC clones are expected to serve as seeds for the physical mapping of these two homologous chromosomes, sequentially map-based cloning of quantitative trait loci or genes associated with important agronomic traits.

关键词： bacterial artificial chromosome library polymerase chain reaction screening simple sequence repeats markers TM-1 upland cotton.

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