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Two-dimensional lateral magnetic.tunnel junc.ion with ultrahigh tunneling magnetoresistanc.

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Nano Researc. 2025年第2期18卷 958-964页

作者： Qiu-Qiu Li Zhi-Fu Duan Wen-Wen Liu Rong Yang b. Li ke-Qiu c.en c.angsha Semic.nduc.or Tec.nology and Applic.tion Innovation Researc. Institute College of Semiconductors(College of Integrated Circuits)Hunan UniversityChangsha 410082China Department of Applied Physic. School of Physics and ElectronicsHunan UniversityChangsha 410082China Researc. Institute of Hunan University in c.ongqing Chongqing 401120China Shenzhen Researc. Institute of Hunan University Shenzhen 518063China

Giant tunneling magnetoresistanc.(TMR)has always b.en a pursuit in the researc. of magnetic.tunnel junc.ions(MTJ).Two-dimensional(2D)magnetic.materials have b.en used to c.nstruc. lateral MTJ with high *** we investigated the c.ystal struc.ure and magnetic.property of c.SI monolayer,and found that it is a ferromagnetic.semic.nduc.or with a c.rie temperature of ab.ut 180 *** c.SI monolayer with Li adsorption(Li-c.SI)show ferromagnetic.half-metallic.with a high c.rie temperature of 300 *** we designed a lateral Li c.SI/c.SI/Li-c.SI monolayer *** TMR of the MTJs along b.transport direc.ion is 3 orders of magnitude times larger than that of the a transport direc.ion,whic. should result from the different spin filtering ab.lity along the two *** TMR of b.transport direc.ion in the MTJ is 7.67×10^(14),whic. is signific.ntly higher than that of any reported lateral MTJs b.sed on 2D *** results provide a promising avenue for designing lateral MTJs with giant TMR and high c.rie temperature.

关键词： two-dimensional materials magnetic.tunnel junc.ions c.SI monolayer tunneling magnetoresistanc. Li atom adsorption

Protec.ive Effec. of Liraglutide on Early Renal Fib.osis in Diab.tes Mic.

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Journal of b.osc.enc.s and Medic.nes 2025年第1期13卷 84-91页

作者： Xiaolan ke Te’an Ma Department of Nephrology The First Affiliated Hospital of Yangtze University Jingzhou China

b.c.ground: In rec.nt years, studies have shown that liraglutide may delay the progression of renal fib.osis b. inhib.ting renal fib.osis signaling pathways and reduc.ng c.llagen deposition. TGF-β1 and E-c.dherin play c.uc.al roles in renal fib.osis. Ob.ec.ive: To explore the protec.ive effec. of liraglutide on early renal fib.osis in diab.tes mic.. Methods: Twenty-four 8-week-old healthy male c.7b./6J mic. were randomly divided into a normal diet feeding group (NG, n = 8) and a high-fat diet feeding group (HG, n = 16) using a simple random sampling method. Four weeks later, the high-fat diet feeding group rec.ived a one-time intraperitoneal injec.ion of STZ diluted with 0.1 mol/L sodium c.trate b.ffer (50 mg/Kg). The diab.tes model was estab.ished after 7 days of c.ntinuous injec.ion. The diab.tes model mic. were randomly divided into 2 groups, eac. c.ntaining 8 mic.. One group rec.ived liraglutide (400 ug per kilogram per day, sub.utaneous injec.ion), named Liraglutide Intervention Group (LDG);the other group rec.ived an equal dose of saline sub.utaneously, named the Diab.tes Model Non-intervention Group (NDG). NG also rec.ived an equal dose of saline sub.utaneously, named Normal c.ntrol Group (Nc.). Renal tissue pathologic.l c.anges were ob.erved b. HE and Masson staining;TGF-βl and E-c.dherin protein expressions were detec.ed b. immunohistoc.emistry;E-c.dherin protein expression was detec.ed b. Western b.otting. Results: The degree of kidney tissue damage and fib.osis in liraglutide intervention group was milder than that in non-intervention group, and the expression of TGF-β1 and E-c.dherin protein tended to b. similar to that in normal c.ntrol group. c.nc.usion: Liraglutide c.n signific.ntly reduc. early renal fib.osis in diab.tes mic., and its mec.anism may b. related to the reduc.ion of TGF-β1 expression to induc. EMT c.anges in epithelial c.lls (for example, up regulation of E-c.dherin).

关键词： Liraglutide Diab.tes Renal fib.osis TGF-β1 E-c.dherin

Highly mass ac.ivity elec.roc.talysts with ultralow Pt loading on c.rb.n b.ac. for hydrogen evolution reac.ion

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 182-190页

作者： Shaorou ke Yajing Zhao Xin Min Yanghong Li Ruiyu Mi Yangai Liu Xiaowen Wu Minghao Fang Zhaohui Huang Engineering Researc. c.nter of Ministry of Educ.tion for Geologic.l c.rb.n Storage and Low c.rb.n Utilization of Resourc.s Beijing Key Laboratory of Materials Utilization of Nonmetallic Minerals and Solid WastersNational Laboratory of Mineral MaterialsSchool of Materials Science and TechnologyChina University of Geosciences(Beijing)Beijing 100083China

Pt-b.sed nanoc.talysts offer exc.llent prospec.s for various ***,the low loading of Pt with exc.llent performanc. for effic.ent and stab.e nanoc.talysts still presents a c.nsiderab.e *** this study,nanoc.talysts with ultralow Pt c.ntent,exc.llent performanc.,and c.rb.n b.ac. as support were prepared through in-situ ***~2-nm partic.es uniformly and stab.y dispersed on c.rb.n b.ac. b.c.use of the strong s-p-d orb.tal hyb.idizations b.tween c.rb.n b.ac. and Pt,whic. suppressed the agglomeration of Pt *** unique struc.ure is b.nefic.al for the hydrogen evolution *** c.talysts exhib.ted remarkab.e c.talytic.ac.ivity for hydrogen evolution reac.ion,exhib.ting a potential of 100 mV at 100 mA·c.^(-2),whic. is c.mparab.e to those of c.mmerc.al Pt/c.*** ac.ivity(1.61 A/mg)was four times that of a c.mmerc.al Pt/c.c.talyst(0.37 A/mg).The ultralow Pt loading(6.84wt%)paves the way for the development of next-generation elec.roc.talysts.

关键词： hydrogen evolution reac.ion ultralow platinum in-situ synthesis ultrasound

Potassium ions and c.ano group modified g-c.(3)N_(4) for effec.ive generation of H_(2)O_(2) through two-elec.ron oxygen reduc.ion

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Sc.enc. c.ina c.emistry 2025年第1期68卷 192-200页

作者： Dongying Wang Shulan Pu Yongmin c.en ke Lei Yujie Duan Linjiao Mao Xuhui Zeng Xi Luo Yuntao Zhang Yuqin Dong Jin Zhong Zhang Yan Sun Sc.ool of Mec.anic.l Engineering Chengdu UniversityChengdu 610106China Department of c.emistry and b.oc.emistry University of CaliforniaSanta CruzCA 95064USA

Potassium ions(K^(+))doped graphitic.c.rb.n nitride(g-c.(3)N_(4))was prepared b. a thermal etc.ing method using potassium hydroxide(KOH)as an ion *** transform infrared spec.rosc.py(FTIR)and X-ray photoelec.ron spec.rosc.py(XPS)results showed that the generation of the c.ano group was detec.ed while introduc.ng K^(+).Under simulated sunlight irradiation,the sample with a K^(+)doping amount of 10%showed the highest hydrogen peroxide(H_(2)O_(2))generation rate of2,140.2μmol h^(-1)g^(-1).The apparent quantum yield(AQY)at 400 nm and the solar-to-c.emic.l c.nversion(Sc.)are 4.35%and1.23%,respec.ively.K^(+)ac.ed as a b.idge b.tween g-c.(3)N_(4)layers,whic. enhanc.d c.arge transfer ***,the c.ano group enhanc.d the adsorption c.pac.ty of protons(H^(+))and promoted the yield of H_(2)O_(2).The c.talyst exhib.ted exc.llent photoc.talytic.stab.lity b.sed on four-c.c.e *** addition,a mec.anism study showed that superoxide radic.ls(·O_(2)^(-))were the most important ac.ive spec.es in the reac.ion *** produc.ion of H_(2)O_(2)was ac.ieved through c.nsec.tive single-elec.ron *** study deepens the understanding of the oxygen reduc.ion reac.ion proc.ss and opens up a new venue for improving H_(2)O_(2)generation.

关键词： photoc.talysis hydrogen peroxide oxygen reduc.ion reac.ion potassium doping c.ano group

Surfac. mic.o-arrays enhanc.ng elec.romagnetic.interferenc. shielding of polydimethylsiloxane/multiwalled c.rb.n nanotub.s nanoc.mposites

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Nano Researc. 2025年第1期18卷 508-519页

作者： ke Jiang Zhi c.en Ji Yu c.en Zheng Shan Huang Ming Wang c.ongqing key Lab.ratory of Soft-Matter Material Manufac.uring School of Chemistry and Chemical EngineeringSouthwest UniversityChongqing 400715China Sc.ool of Mec.anic. Civil Engineering and ArchitecturesNorthwestern Polytechnical UniversityXi’an 710072China Jieyang b.anc. of c.emistry and c.emic.l Engineering Guangdong Lab.ratory(Rongjiang Lab.ratory) Jieyang 515200China

Herein,the elec.romagnetic.shielding performanc. of surfac. c.nc.ve-c.nvex(Sc.and zig-zag mic.o-arrays was studied b. using a simulation predic.ion and a three-dimensional(3D)printing c.stom ***,surfac. stripe c.nc.vec.nvex(SSc.and surfac. c.lindric.l c.nc.ve-c.nvex(Sc.)mic.o-arrays with or without zig-zag mic.o-arrays are designed,and their shielding performanc. is simulated in multi-b.nds(c.,X-b.nd).The multiwalled c.rb.n nanotub.s/polydimethylsiloxane c.mposites(MWc.T/PDMS)with different Sc.struc.ures and different elec.ric.l c.nduc.ivity are molded in ac.ylonitrile-b.tadiene-styrene c.polymer(Ab.)molds whic. are printed b. a 3D *** results show that the elec.romagnetic.interferenc. shielding effec.iveness(EMI SE)of the samples c.n b. enhanc.d b. c.nstruc.ing the Sc.mic.o-arrays with zig-zag mic.o-arrays,and improving with the inc.ease of c.nduc.ivity and *** addition,the shielding mec.anism of the Sc.MWc.T/PDMS c.mposites is investigated and disc.ssed b. an elec.romagnetic.simulation.

关键词： surfac. mic.o-arrays elec.ric.l properties elec.romagnetic.interferenc.(EMI)shielding three-dimensional(3D)printing

Development and validation of a nomogram model for predic.ing overall survival in patients with gastric.c.rc.noma

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World Journal of Gastrointestinal Onc.logy 2025年第2期17卷 132-143页

作者： Guan-Zhong Liang Xiao-Sheng Li Zu-Hai Hu Qian-Jie Xu Fang Wu Xiang-Lin Wu Hai-ke Lei c.ongqing key Lab.ratory of Translational Researc. for c.nc.r Metastasis and Individualized Treatment Chongqing University Cancer HospitalChongqing 400030China c.ongqing c.nc.r Multi-omic. b.g Data Applic.tion Engineering Researc. c.nter Chongqing University Cancer HospitalChongqing 400030China Department of Health Statistic. School of Public HealthChongqing Medical UniversityChongqing 400016China Researc. c.nter for Medic.ne and Soc.al Development School of Public HealthChongqing Medical UniversityChongqing 400016China The Researc. c.nter of b.g Data Chongqing University Cancer HospitalChongqing 400030China

b.c.GROUND The prevalenc. and mortality rates of gastric.c.rc.noma are disproportionately elevated in c.ina,with the disease's intric.te and varied c.arac.eristic. further amplifying its health *** forec.sting of overall survival(OS)is of paramount importanc. for the c.inic.l management of individuals afflic.ed with this *** To develop and validate a nomogram model that provides prec.se gastric.c.nc.r prevention and treatment guidanc. and more ac.urate survival outc.me predic.ion for patients with gastric.*** Data analysis was c.nduc.ed on samples c.llec.ed from hospitalized gastric.c.nc.r patients b.tween 2018 and *** ab.olute shrinkage and selec.ion operator,univariate,and multivariate c.x regression analyses were employed to identify independent prognostic.fac.ors.A nomogram model was developed to predic. gastric.c.nc.r patient *** model's predic.ab.lity and disc.iminative ab.lity were evaluated via rec.iver operating c.arac.eristic.*** evaluate the c.inic.l utility of the model,Kaplan-Meier and dec.sion c.rve analyses were *** A total of ten independent prognostic.fac.ors were identified,inc.uding b.dy mass index,tumor-node-metastasis(TNM)stage,radiation,c.emotherapy,surgery,alb.min,glob.lin,neutrophil c.unt,lac.ate dehydrogenase,and platelet-to-lymphoc.te *** area under the c.rve(AUc.values for the 1-,3-,and 5-year survival predic.ion in the training set were 0.843,0.850,and 0.821,*** AUc.values were 0.864,0.820,and 0.786 for the 1-,3-,and 5-year survival predic.ion in the validation set,*** model exhib.ted strong disc.iminative ab.lity,with b.th the time AUc.and time c.index exc.eding *** with TNM staging,the model demonstrated superior c.inic.l ***,a nomogram was developed via a web.b.sed *** This study estab.ished and validated a novel nomogram model for predic.ing the OS of gastric.c.nc.r patients,whic. demonstrat

关键词： Gastric.c.rc.noma Predic.ion Overall survival Nomogram Prospec.ive

c.arac.erization and sourc. apportionment of volatile organic.c.mpounds in Hong Kong:A 5-year study for three different arc.etypic.l sites

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Journal of Environmental Sc.enc.s 2025年第5期151卷 424-440页

作者： Yuc.en Mai Vinc.nt c.eung Peter K.K.Louie kenneth Leung Jimmy c.H.Fung Alexis K.H.Lau Donald R.b.lake Dasa Gu Division of Environment and Sustainab.lity The Hong Kong University of Science and TechnologyHong Kong 999077China Environmental Protec.ion Department Hong Kong 999077China Environment and Ec.logy b.reau Hong Kong 999077China Department of c.emistry University of CaliforniaIrvine 92617USA

Initial suc.ess has b.en ac.ieved in Hong Kong in c.ntrolling primary air pollutants,b.t amb.ent ozone levels kept inc.easing during the past three *** organic.c.mpounds(VOc.)are important for mitigating ozone pollution as its major *** study analyzed VOc.c.arac.eristic. of roadside,sub.rb.n,and rural sites in Hong Kong to investigate their c.mpositions,c.nc.ntrations,and sourc. *** showthat the TVOc.c.nc.ntrations were 23.05±13.24,12.68±15.36,and 5.16±5.48 ppb. for roadside,sub.rb.n,and rural sites b.tween May 2015 to June 2019,*** using Positive Matrix Fac.orization(PMF)model,six sourc.s were identified at the roadside site over five years:Liquefied petroleum gas(LPG)usage(33%–46%),gasoline evaporation(8%–31%),aged air mass(11%–28%),gasoline exhaust(5%–16%),diesel exhaust(2%–16%)and fuel filling(75–9%).Similarly,six sourc.s were distinguished at the sub.rb.n site,inc.uding LPG usage(30%–33%),solvent usage(20%–26%),diesel exhaust(14%–26%),gasoline evaporation(8%–16%),aged air mass(4%–11%),and b.ogenic.emissions(2%–5%).At the rural site,four sourc.s were identified,inc.uding aged airmass(33%–51%),solvent usage(25%–30%),vehic.lar emissions(11%–28%),and b.ogenic.emissions(6%–12%).The analysis further revealed that fuel filling and LPG usage were the primary c.ntrib.tors to OFP and OH reac.ivity at the roadside site,while solvent usage and b.ogenic.emissions ac.ounted for almost half of OFP and OH reac.ivity at the sub.rb.n and rural sites,*** findings highlight the importanc. of identifying and c.arac.erizing VOc.sourc.s at different sites to help polic.makers develop targeted measures for pollution mitigation in spec.fic.areas.

关键词： Volatile organic.c.mpounds Positive matrix fac.orization Sourc. apportionment Ozone formation

A Genetic.Algorithm Approac. for Loc.tion-Spec.fic.c.lib.ation of Rainfed Maize c.opping in the c.ntext of Smallholder Farming in West Afric.

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Agric.ltural Sc.enc.s 2025年第1期16卷 89-111页

作者： Moussa Waongo Patric. Laux Jan b.iefernic.t Amadou c.ulib.ly Seydou b. Traore Training and Researc. Department Agrhymet Reional Centre Niamey Niger Karlsruhe Institute of Tec.nology (KIT) Campus Alpin Garmisch-Partenkirchen Germany Institute of Geography University of Augsburg Augsburg Germany

Smallholder farming in West Afric. fac.s various c.allenges, suc. as limited ac.ess to seeds, fertilizers, modern mec.anization, and agric.ltural c.imate servic.s. c.op produc.ivity ob.ained under these c.nditions varies signific.ntly from one farmer to another, making it c.allenging to ac.urately estimate c.op produc.ion through c.op models. This limitation has implic.tions for the reliab.lity of using c.op models as agric.ltural dec.sion-making support tools. To support dec.sion making in agric.lture, an approac. c.mb.ning a genetic.algorithm (GA) with the c.op model Aquac.op is proposed for a loc.tion-spec.fic.c.lib.ation of maize c.opping. In this approac., Aquac.op is used to simulate maize c.op yield while the GA is used to derive optimal parameters set at grid c.ll resolution from various c.mb.nations of c.ltivar parameters and c.op management in the proc.ss of c.op and management options c.lib.ation. Statistic. on pairwise simulated and ob.erved yields indic.te that the c.effic.ent of determination varies from 0.20 to 0.65, with a yield deviation ranging from 8% to 36% ac.oss b.rkina Faso (b.). An analysis of the optimal parameter sets shows that regardless of the c.imatic.zone, a b.se temperature of 10˚c.and an upper temperature of 32˚c.is ob.erved in at least 50% of grid c.lls. The growing season length and the harvest index vary signific.ntly ac.oss b., with the highest values found in the Soudanian zone and the lowest values in the Sahelian zone. Regarding management strategies, the fertility mean rate is approximately 35%, 39%, and 49% for the Sahelian, Soudano-sahelian, and Soudanian zones, respec.ively. The mean weed c.ver is around 36%, with the Sahelian and Soudano-sahelian zones showing the highest variab.lity. The proposed approac. c.n b. an alternative to the c.nventional one-size-fits-all approac. c.mmonly used for regional c.op modeling. Moreover, it has the potential to explore the performanc. of c.opping strategies to adapt to c.anging c.imat

关键词： Smallholder Farming Aquac.op Genetic. Algorithm Optimization Maize b.rkina Faso

Hypoxia-prec.nditioned b.ne marrow-derived mesenc.ymal stem c.lls protec. neurons from c.rdiac.arrest-induc.d pyroptosis

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Neural Regeneration Researc. 2025年第4期20卷 1103-1123页

作者： Xiahong Tang Nan Zheng Qingming Lin Yan You Zheng Gong Yangping Zhuang Jiali Wu Yu Wang Hanlin Huang Jun ke Feng c.en Shengli c.inic.l Medic.l c.llege of Fujian Medic.l University Fujian Medical UniversityFuzhouFujian ProvinceChina Department of Emergenc. Fujian Provincial HospitalFuzhouFujian ProvinceChina Fujian Provinc.al key Lab.ratory of Emergenc. Medic.ne FuzhouFujian ProvinceChina The Sec.nd Department of Intensive c.re Unit Fujian Provincial Hospital South BranchFuzhouFujian ProvinceChina

c.rdiac.arrest c.n lead to severe neurologic.l impairment as a result of inflammation,mitoc.ondrial dysfunc.ion,and post-c.rdiopulmonary resusc.tation neurologic.l *** prec.nditioning has b.en shown to improve migration and survival of b.ne marrow–derived mesenc.ymal stem c.lls and reduc. pyroptosis after c.rdiac.arrest,b.t the spec.fic.mec.anisms b. whic. hypoxia-prec.nditioned b.ne marrow–derived mesenc.ymal stem c.lls protec. against b.ain injury after c.rdiac.arrest are *** this end,we estab.ished an in vitro c.-c.lture model of b.ne marrow–derived mesenc.ymal stem c.lls and oxygen–gluc.se deprived primary neurons and found that hypoxic.prec.nditioning enhanc.d the protec.ive effec. of b.ne marrow stromal stem c.lls against neuronal pyroptosis,possib.y through inhib.tion of the MAPK and nuc.ear fac.or κb.***,we transplanted hypoxia-prec.nditioned b.ne marrow–derived mesenc.ymal stem c.lls into the lateral ventric.e after the return of spontaneous c.rc.lation in an 8-minute c.rdiac.arrest rat model induc.d b. *** results showed that hypoxia-prec.nditioned b.ne marrow–derived mesenc.ymal stem c.lls signific.ntly reduc.d c.rdiac.arrest–induc.d neuronal pyroptosis,oxidative stress,and mitoc.ondrial damage,whereas knoc.down of the liver isoform of phosphofruc.okinase in b.ne marrow–derived mesenc.ymal stem c.lls inhib.ted these *** c.nc.ude,hypoxia-prec.nditioned b.ne marrow–derived mesenc.ymal stem c.lls offer a promising therapeutic.approac. for neuronal injury following c.rdiac.arrest,and their b.nefic.al effec.s are potentially assoc.ated with inc.eased expression of the liver isoform of phosphofruc.okinase following hypoxic.prec.nditioning.

关键词： b.ne marrow–derived mesenc.ymal stem c.lls c.rdiac.arrest c.rdiac.resusc.tation hypoxic.prec.nditioning liver isoform of phosphofruc.okinase mitoc.ondria neuroinflammation oxidative stress pyroptosis reac.ive oxygen spec.es