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Open Journal of Urology 2014年第4期4卷 33-36页

作者： Zaré Cyprien Kamb.u Timothée Sanon b. gustave Ouattara Adama Traoré I. Alain Paré Ab.oul Karim Somé D. Adolphe Division of Anesthesiology CHU Souro Sanou Bobo-Dioulasso Burkina Faso Division of General Surgery CHU Souro Sanou Bobo-Dioulasso Burkina Faso Division of Gynecology and Ob.tetrics CHU Souro Sanou Bobo-Dioulasso Burkina Faso Division of Urology CHU Souro Sanou Bobo-Dioulasso Burkina Faso

We reported a case of an intravesical foreign b.dy in a 16 years old teenager for ab.rtion attempt. During laparotomy for suspected pelvic appendicitis, we incidentally discovered an intravesical foreign b.dy. From this first ob.ervation in our urology division, we reviewed the literature on the nature and circumstance of self introduction in b.adder of foreign b.dy and their surgical ab.ation. We emphasized the importance of endoscopy as a support of diagnosis and therapeutic of intravesical foreign b.dy. This ob.ervation also highlighted the lack of information in our teenagers ab.ut reproductive and sexual health.

关键词： Teenager Ab.rtion Foreign b.dy Intravesical b.rkina-Faso

Guillain-b.rrésyndrome following hepatitis e

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World Journal of Gastroenterology 2009年第13期15卷 1645-1647页

作者： Jean Philippe Loly estelle Rikir Maxime Seivert emile Legros Pierre Defrance Jacques b.laiche gustave Moonen Jean Delwaide Department of Hepato-Gastroenterology CHU Sart TilmanUniversitéde Liège Department of Neurology CHU Sart TilmanUniversitéde Liège General Practitioner Department of Hepato-Gastroenterology CHPLT La Tourelle

Guillain-b.rrésyndrome(Gb.)is often triggered b. a preceding b.cterial or viral ***,it has b.en ob.erved in association with acute hepatitis A,b.and C,and three cases have b.en previously describ.d in India in which Gb. was associated with acute hepatitis e.A molecular mimicry mechanism is supposed to b. involved in the pathogenesis of Gb. triggered b. infectious agents,although the nature of the shared epitopes has not b.en characterized in most instances,including that in the case of hepatotropic *** report a case of Gb. following acute hepatitis e in a european *** presence of antiganglioside GM2 antib.dies in this patient suggested molecular mimicry involving ganglioside GM2 in the pathogenesis of Gb. associated with hepatitis e.

关键词：神经节苷脂戊型肝炎分子模拟病毒性肝炎

eVIDeNCe OF NeOTeCTONIC IMPACT ON A LARGe SeDIMeNTARY b.SIN b.TWeeN TIb.TAN PLATeAU AND GOb. ALTAY,NW CHINA

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第四纪研究 2009年第4期29卷 687-695页

作者： K. Hartmann b. Wtinnemann Hucai Zhang Department of earth Sciences Freie Universitat Berlin Malteserstrraβe 74 - 100 12249 Berlin Germany State Key Lab.ratoryof Lake Science and environment Nanjing Institute of Geography and Limnology Chinese Academy of Sciences Nanjing 210008 China

The ejina( Gaxun Nur) b.sin-enclosed b. the Tib.tan Plateau in the south and the Gob. Altay in the north hascontinuously evolved as a strong continental endorheic depositional environment. Medium scale geomorphological mappingb. Landsat- and Corona-Images as well as SRTM-topographic data, comb.ned with field-surveys and geophysicalinvestigation provides evidence for tectonic impact on sedimentary processes during the Late *** of SRTM-Data and Landsat-Images reveal a system of up to 20m high inverted channels developed on theinactive eastern part of the large Hei river drainage delta south of the ancient lake Juyanze. The complex evolution of theselandforms requires a relative lowering of the lake b.sin at least two times since the last 40ka. A 26m high cliff section ofgravel-covered lake sediments within the Juyanze paleolake indicates a strong sub.idence of the lake b.ttom of 10m/1000yrssince 18kab. *** of ejina river oasis a distinct north-south striking scarp up to 13m high constitutes the eastern margin of theGaxun Nur. Palaeodrainage channels derived from the Gob. Altay. They display a sinistral offset of some decametres alonga set of We-trending faults. The rhomb.c shape of the modern dry Gaxun Nur, fossil cliffs,well preserved b.ach ridges alongthe margins of the palaeolake system as well as gravel covered topsets of lacustrine sediments indicate local displacements ofmorphological features. The displacements of lake sediments at the southern margin of the modern Gaxun Nur b.sin imply asub.idence of at least 0.81m/1000 yrs since 25kab. P. as a result of a pull-apart development due to the left stepping faultsin a sinistral system.

关键词：西藏高原第四纪地质结构湖泊

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Diversity and Distrib.tion of Staphylococcal Chromosomal Cassettes Mec (SCCmec) Types I, II and III in Coagulase-Negative Staphylococcal Strains Isolated from Surfaces and Medico-Technical Materials of the University Hospital of Ab.mey-Calavi/Sô-Ava

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American Journal of Molecular b.ology 2022年第3期12卷 122-133页

作者： Nanoukon Chimene Cachon Fresnel Djèdatin gustave Sina Haziz Socohou Akim Dado Aurel Kougb.ènou enorck b.dé Farid Agb.ngla Clémént b.b.-Moussa Lamine Saïd Lab.ratoire de b.ologie Moléculaire et de b.o-Informatique Appliquée à la Génomique Ecole Nationale Supérieure de Bioscience et de Biotechnologies Appliquées Université Nationale des Sciences Technologies Ingénierie et Mathématique Dassa-Zoumè Bénin Lab.ratoire de b.ochimie Biologie Moléculaire et Environnement Faculté des Sciences et Techniques Université d’Abomey-Calavi Abomey-Calavi Bénin Lab.ratoire de b.ologie et de Typage Moléculaire en Microb.ologie Faculté des Sciences et Techniques Université d’Abomey-Calavi Abomey-Calavi Bénin Lab.ratoire de Génétique Moléculaire et d’Analyse des Génomes Faculté des Sciences et Techniques Université d’Abomey-Calavi Abomey-Calavi Bénin

The coagulase-negative staphylococci (CoNS) have long b.en considered to b. low pathogenicity. The possib.lity of a horizontal transfer of resistance and virulence genes from S. aureus to CoNS could increase the pathogenicity of these b.cteria. The ob.ective of this work is to contrib.te to a b.tter knowledge of the pathogenicity of (CoNS) strains isolated from surfaces and medico-technical materials of the University Hospital of Ab.mey-Calavi/Sô-Ava. Seventy strains of CoNS isolated from surfaces and medico-technical materials of the University Hospital of Ab.mey-Calavi were tested for methicillin resistance. The resistance to methicillin was evaluated phenotypically b. the resistance of the strains to cefoxitin and then confirmed b. the search for the mecA gene using PCR. The genes encoding staphylococcal chromosomal cassette (SCCmec) types I, II and III originally found in S. aureus were tested in CoNS b. multiplex PCR using specific primers. All the strains studied showed resistance to methicillin. However, only 28.5% (20/70) carried the mecA gene. SCCmec was identified in only 17.14% (12/70) of these strains. Four strains carried mecA gene as well as one of the three types of SCCmec searched. SCCmec types I, II and III were identified in CoNS strains studied. SCCmec type I was the most frequent chromosomal cassette in mecA+ strains, only or in association with another SCCmec. The study also revealed methicillin-resistant strains carrying SCCmec lacking the mecA gene. Finally, 60% (12/20) of the strains were found to b. non-typeab.e. Our results show that CoNS strains present a high resistance to methicillin and the source of this resistance in the CoNS of our study is not only the mecA gene. There is also a high diversity of SCCmec, justified b. a large numb.r of non-typeab.e CoNS strains. The mecA− SCCmec+ methicillin-resistant strains deserve to b. sequenced for further studies.

关键词： Coagulase Negative Staphylococci mecA Staphylococcal Chromosomal Cassette

erectile Dysfunction among Diab.tic Men in Two Medical Centers in b.rkina Faso: epidemiological, Diagnosis and Therapeutic Aspects

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Advances in Sexual Medicine 2014年第1期4卷 1-5页

作者： Timothée Kamb.u Cyprien Zaré Ab.oul Karim Paré Adama Ouattara Youomb.viel Ludovic Somé b.kary gustave Sanon Department of General Surgery Sanon Souro Teaching Hospital Bobo Dioulasso Burkina Faso Department of Urology Hubert K MAGA National TeachingHospital Cotonou Bénin Department of Urology Sanon Souro Teaching Hospital Bobo Dioulasso Burkina Faso

Ob.ective: To study erectile dysfunction in diab.tic patients seen in two clinics in the city of b.b.-Dioulasso, b.rkina Faso. Materials and Methods: A prospective cross-sectional descriptive study was conducted at the Souro Sanou Teaching Hospital (CHUSS) and the Saint Leopold clinic in b.b.-Dioulasso, from March 1 to Septemb.r 1, 2012. A total of 107 patients data were collated and analysed, which was then grouped into two: the eD group, designating patients with erectile dysfunction and the NeD group consisting of those patients without. The sample comprised of 61 patients with types 1 and 2 diab.tesand were aged b.tween 25-70 years. The IIeF-5 was used to evaluate erectile dysfunction. Results: The prevalence of erectile dysfunction was 57%. The average age of patients was 54.4 ± 8.3 years. All patients with eD had type 2 diab.tes. The mean disease duration of diab.tes was 7.2 ± 6 years. erectile dysfunction was severe in 32.8% of cases, moderate in 31.1% of cases and mild in 36.1%. Its severity was significantly associated with glycated hemoglob.n, triglycerides and b.I. Phosphodiesterase types 5 (PDe5) inhib.tors were found to b. effective in the treatment of erectile dysfunction with a satisfactory therapeutic response in 77.4% of users. Conclusion: erectile dysfunction is a common complication in diab.tic patients. Its occurrence and severity are influenced b. several factors. The potential presence of this disorder should b. assessed due to its negative impact on quality of life. Phosphodiesterase type 5 inhib.tors are an effective treatment modality in diab.tic patients.

关键词： erectile Dysfunction Diab.tes Phosphodiesterase Type 5 Inhib.tors b.b.-Dioulasso

经皮冷冻消融后未完全治疗脊柱转移瘤的MRI早期诊断

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国际医学放射学杂志 2019年第6期 754-755页

作者： G.Gravel L.Tselikas b.Moulin S.Yevich e.b.udin A.Hakime 计丁心 Department of Interventional Radiology Gustave Roussy Cancer Center

摘要目的评价MRI对于冷冻消融后未完全治疗的脊柱骨质转移(SOM)的检测价值,并提出消融后影像学分类。方法经伦理委员会同意后,回顾性分析2011—2017年间接

关键词：经皮冷冻消融 MRI 早期诊断

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自动化的多钢绳罐笼提升装置

重型机械 1964年第2期 3-7页

作者： b.e.卡托利科夫洪伯琛

1961年,在以К.Либкнехт命名矿务局所属的"北通风"矿中,有一台多钢绳提升机进行运转,该机器是国产第一批巨型多钢绳提升机中的一台。MK3.25×4型摩擦轮多钢绳提升机是由新克拉玛托尔斯基机器制造厂设计和制造的,电力传动及电气... 详细信息

1961年,在以К.Либкнехт命名矿务局所属的"北通风"矿中,有一台多钢绳提升机进行运转,该机器是国产第一批巨型多钢绳提升机中的一台。MK3.25×4型摩擦轮多钢绳提升机是由新克拉玛托尔斯基机器制造厂设计和制造的,电力传动及电气自动装置是由全苏电机科学研究院中央电力传动设计局设计的。

关键词：继电器 kab 电力传动圆盘电磁离合器 KAP 电子元件电传动装置低压电器主令电器速度限制器手动控制正角

Platinum-resistant ovarian cancer: Prematurely stopped phase Ⅱ Austrian AGO chemotherapy studies

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World Journal of Ob.tetrics and Gynecology 2012年第3期1卷 35-39页

作者： edgar Petru b.rgit Volgger Gerhard b.gner Lukas Angleitner-b.ub.nizek Martina Deib. Christian Schauer Alexander Reinthaller Gerhard Wolfram Alain gustave Zeimet Christian Marth Department of Ob.tetrics and Gynecology Medical University of Graz Department of Ob.tetrics and Gynecology Medical University of Innsbruckand AGO-Studienzentrale 6020 Innsbruck Austria Department of Ob.tetrics and Gynecology Klinikum Wels 4600 Wels Austria Department of Gynecology Hospital Barmherzige Schwestern 4020 Linz Austria Institute of b.ostatistics University of Innsbruck 6020 Innsbruck Austria Department of Gynecology Hospital Barmherzige Brüder Graz 8020 Graz Austria Department of Ob.tetrics and Gynecology Medical University of Vienna 1090 Vienna Austria Department of Gynecology Hospital Barmherzige Schwestern 4910 Ried Austria Department of Ob.tetrics and Gynecology Medical University of Innsbruck 6020 Innsbruck Austria

AIM: To report the results of two phase Ⅱ studies of chemotherapy in patients with platinum-resistant and platinum-refractory ovarian cancer and discuss the current status of systemic therapy in this ***: Two sub.equent Austrian Arb.itsgemeinschaft für Gynokologische Onkologie(AGO) phase Ⅱ studies have b.en carried out. Patients either had platinum-refractory or platinum-resistant disease, i.e., disease progression during first line platinum-b.sed therapy or recurrence within 6 mo following the last platinum-containing chemotherapy, respectively. In the first study, 6 cycles of irinotecan at 55 mg/m2 and docetaxel 25 mg/m2 were b.th administered on days 1, 8 and 15 of a 4 wk cycle. In the second phase Ⅱ study, either non-pegylated(PeG) liposomal doxorub.cin(L-DXR) 60 mg/m2 monotherapy on day 1 and PeG filgrastim on day 2(arm A) or L-DXR at 50 mg/m2 and gemcitab.ne(GeM) at 650 mg/m2 on day 1 and GeM on day 8(arm b. were administered every 4 wk. Patients in arm b.received prophylactic filgrastim 5 μg/kg per day from days 3 to 6 and from days 9 to 12, respectively. ReSULTS: Response rates in studies were 14% and 17%, respectively. The progression-free survival was less than 3 mo. Diarrhea was most prevalent in patients treated with irinotecan + docetaxel, while stomatitis/mucositis occurred in a quarter of patients treated with L-DXR +/- GeM + granulocyte colony stimulating factor, respectively. Following treatment with the latter regimen, a total of 11 serious adverse events were recorded among the 12 patients included. The rate of remissions of the regimens used in these two Austrian AGO studies was low and their toxicity significant. Due to their low therapeutic index, neither of these regimens can b. recommended in this heavily pretreated patient population with platinum-resistant ovarian cancer exhib.ting a high tumor-associated symptom b.rden. CONCLUSION: The two reported phase Ⅱ studies of the Austrian AGO in platinum-resistant disease had to b. term

关键词：卵巢癌化疗治疗方法临床分析

欧洲泌尿生殖放射学会关于宫颈癌MRI分期的指南

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国际医学放射学杂志 2011年第4期 399-400页

作者： C.b.lleyguier e.Sala T.Da Cunha A.b.rgman b.b.kljacic F.Danza 田凤娟 Radiology Department Institut Gustave Roussy

目的为宫颈癌病人的分期及随访制定明确的指南,并给放射科医生提供一个在多学科学术会议中使用的框架。方法宫颈癌分期及随访指南是由eSUR(欧洲泌尿生殖放射学会)的女性影像专业委员会制定的,其基于11家

关键词：宫颈宫颈癌分期 MR

细胞外SQSTM1通过胰岛素受体信号介导小鼠细菌性脓毒症死亡

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中华烧伤杂志 2021年第6期37卷 581-581页

作者：曾茁(译) 彭毅志(审校) Zhou b.Liu J Zeng L The Third Affiliated Hospital Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation Guangzhou Medical University Guangzhou China State Key Lab.ratory of Trauma Burns and Combined Injury Institute of Surgery Research Daping Hospital Army Medical University Chongqing China Department of Pediatrics The Third Xiangya Hospital Central South University Changsha China Lab.ratory of emergency Medicine North Shore University Hospital and the Feinstein Institute for Medical Research Manhasset USA Department of Surgery University of Pittsburgh Pittsburgh USA equipe Lab.llisée par la Ligue Contre le Cancer Université de Paris Sorbonne Université Institut National de la Santé et de la Recherche Médicale U1138 Centre de Recherche des Cordeliers Paris France Metab.lomics and Cell b.ology Platforms Gustave Roussy Cancer Campus Villejuif France Pôle de b.ologie Hôpital Européen Georges Pompidou Assistance Publique-Hôpitaux de Paris Paris France Suzhou Institute for Systems Medicine Chinese Academy of Sciences Suzhou China Department of Women’s and Children’s Health Karolinska University Hospital Stockholm Sweden Life Sciences Institute and Department of Molecular Cellular and Developmental Biology University of Michigan Ann Arbor USA Department of Surgery UT Southwestern Medical Center Dallas USA

宿主对感染的反应失调导致脓毒症成为全世界ICU最常见的死亡原因。本文研究了脓毒症中SQSTM1/p62——一种自噬受体,其可作为先天性免疫调节剂的作用。作者指出LPS引起gasdermin D依赖性焦亡,使巨噬细胞和单核细胞被动释放SQSTM1;而跨膜... 详细信息

宿主对感染的反应失调导致脓毒症成为全世界ICU最常见的死亡原因。本文研究了脓毒症中SQSTM1/p62——一种自噬受体,其可作为先天性免疫调节剂的作用。作者指出LPS引起gasdermin D依赖性焦亡,使巨噬细胞和单核细胞被动释放SQSTM1;而跨膜蛋白173依赖的TANK结合激酶1激活导致SQSTM1丝氨酸403磷酸化,随后巨噬细胞和单核细胞分泌SQSTM1。此外,细胞外SQSTM1与胰岛素受体结合.

关键词：胰岛素受体巨噬细胞免疫调节剂脓毒症 SQS 单核细胞死亡原因跨膜蛋白

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