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Computers, Materials & Continua 2024年第8期80卷 3351-3377页

作者： TugbaÇelikten aytug onan Department of Software Engineering Faculty of TechnologyManisa Celal Bayar UniversityManisa45140Turkey Department of Computer Engineering Faculty of Engineering and ArchitectureIzmir KatipÇelebi UniversityIzmir35620Turkey

Class Title:Radiological imaging method a comprehensive overview *** GPT paper provides an overview of the different forms of radiological imaging and the potential diagnosis capabilities they offer as well as recent advances in the *** and Methods:This paper provides an overview of conventional radiography digital radiography panoramic radiography computed tomography and cone-beam computed *** recent advances in radiological imaging are discussed such as imaging diagnosis and modern computer-aided diagnosis ***:This paper details the differences between the imaging techniques the benefits of each and the current advances in the field to aid in the diagnosis of medical ***:Radiological imaging is an extremely important tool in modern medicine to assist in medical *** work provides an overview of the types of imaging techniques used the recent advances made and their potential applications.

关键词： Generative artificial intelligence AI-generated text detection attention mechanism hybrid model for text classification

AID4I:An Intrusion Detection Framework for Industrial Internet of Things Using Automated Machine Learning

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Computers, Materials & Continua 2023年第8期76卷 2121-2143页

作者： Anil Sezgin aytug Boyacı ATASAREN National Defence UniversityIstanbul34334Turkey Software in Motion Department Siemens AdvantaSiemens Corporate TechnologyIstanbul34870Turkey Department of Computer Engineering National Defence University Air Force AcademyIstanbul34149Turkey

By identifying and responding to any malicious behavior that could endanger the system,the Intrusion Detection System(IDS)is crucial for preserving the security of the Industrial Internet of Things(IIoT)*** benefit of anomaly-based IDS is that they are able to recognize zeroday attacks due to the fact that they do not rely on a signature database to identify abnormal *** order to improve control over datasets and the process,this study proposes using an automated machine learning(AutoML)technique to automate the machine learning processes for *** groundbreaking architecture,known as AID4I,makes use of automatic machine learning methods for intrusion *** automation of preprocessing,feature selection,model selection,and hyperparameter tuning,the objective is to identify an appropriate machine learning model for intrusion *** studies demonstrate that the AID4I framework successfully proposes a *** integrity,security,and confidentiality of data transmitted across the IIoT network can be ensured by automating machine learning processes in the IDS to enhance its capacity to identify and stop threatening *** a comprehensive solution that takes advantage of the latest advances in automated machine learning methods to improve network security,AID4I is a powerful and effective instrument for intrusion *** preprocessing module,three distinct imputation methods are utilized to handle missing data,ensuring the robustness of the intrusion detection system in the presence of incomplete *** selection module adopts a hybrid approach that combines Shapley values and genetic *** Parameter Optimization module encompasses a diverse set of 14 classification methods,allowing for thorough exploration and optimization of the parameters associated with each *** carefully tuning these parameters,the framework enhances its adaptability and accuracy in identifying potential

关键词： Automated machine learning intrusion detection system industrial internet of things parameter optimization

天麻素通过CCR5/JAK1/STAT1信号通路抑制缺血缺氧新生小鼠小胶质细胞介导的炎症反应

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中国病理生理杂志 2024年第2期40卷 309-316页

作者：石金沙石浩龙左涵珺郭涛张幸霖张皓南李经辉李娟娟昆明医科大学基础医学院人体解剖与组织胚胎学系云南昆明650500 昆明医科大学第一附属医院神经外二科云南昆明650032

目的:探究天麻素(GAS)通过C-C趋化因子受体5(CCR5)对新生小鼠缺血缺氧性脑损伤(HIBD)后小胶质细胞JAK1/STAT1信号通路及其介导的炎症反应的影响。方法:选择新出生10 d的C57BL/6J小鼠48只,随机分为假手术(sham)组、HIBD模型组和HIBD与GA... 详细信息

目的:探究天麻素(GAS)通过C-C趋化因子受体5(CCR5)对新生小鼠缺血缺氧性脑损伤(HIBD)后小胶质细胞JAK1/STAT1信号通路及其介导的炎症反应的影响。方法:选择新出生10 d的C57BL/6J小鼠48只,随机分为假手术(sham)组、HIBD模型组和HIBD与GAS联合处理(HIBD+GAS)组;体外培养BV-2小胶质细胞,分为对照(Con)组、氧糖剥夺(OGD)组、OGD+GAS组、GAS组、Maraviroc(MVC)组、OGD+MVC组和OGD+MVC+GAS组。通过RT-qPCR检测CCL4和CCR5的mRNA表达变化,Western blot检测CCR5、p-JAK1、p-STAT1、肿瘤坏死因子α(TNF-α)和白细胞介素1β(IL-1β)蛋白的表达变化,免疫荧光双标染色检测CCR5、p-JAK1和p-STAT1的表达变化。结果:(1)与sham组相比,HIBD组小鼠缺血侧胼胝体区CCL4和CCR5的mRNA水平,以及CCR5、p-JAK1和p-STAT1的蛋白水平明显增高(P<0.05),而HIBD+GAS组中CCL4和CCR5 mRNA水平,以及CCR5、p-JAK1和p-STAT1的蛋白水平显著低于HIBD组(P<0.05)。(2)与Con组相比,OGD组BV-2细胞中CCR5、p-JAK1和p-STAT1蛋白水平明显增高(P<0.05),而OGD+GAS组BV-2细胞中CCR5、p-JAK1和p-STAT1蛋白水平显著低于OGD组(P<0.05)。(3)CCR5拮抗剂MVC在0~80μmol/L范围内不会导致显著的BV-2细胞死亡。与OGD组相比,MVC+OGD组p-JAK1、p-STAT1、TNF-α和IL-1β蛋白水平显著降低(P<0.05),而MVC+OGD组与OGD+MVC+GAS组无明显差异。结论:GAS可通过靶向CCR5抑制小胶质细胞p-JAK1/p-STAT1通路及相关炎症因子的表达,发挥神经保护作用。

关键词：缺血缺氧性脑损伤氧糖剥夺天麻素小胶质细胞 CCR5/JAK1/STAT1信号通路

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A practical approach to imaging characteristics and standardized reporting of COVID-19:A radiologic review

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Military Medical Research 2021年第3期8卷 424-432页

作者： Deniz Esin Tekcan Sanli Duzgun Yildirim Ahmet Necati Sanli Suha Turkmen Neval Erozan Guray Husmen aytug Altundag FilizTuzuner Department of Radiology Acibadem Kozyatagi Hospital19 Mayis Mahinonu CadOkur SokNo.24/Af Kozyatagi34734 IstanbulTurkey Department of Radiology Acibadem Taksim Hospital34373 IstanbulTurkey Cerrahpasa Medical Faculty Department of General SurgeryIstanbul University-Cerrahpasa34098 IstanbulTurkey Department of Emergency Acibadem Taksim Hospital34373 IstanbulTurkey Department of Otolaryngology Acibadem Taksim Hospital34373 IstanbulTurkey Department of Anesthesiology Acibadem Taksim Hospital34373 IstanbulTurkey

Novel coronavirus(2019-nCoV),also known as severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),is a pathogen that has caused a rapidly spreading pandemic all over the *** primary mean of transmission is inhalation with a predilection for respiratory system involvement,especially in the distal *** disease that arises from this novel coronavirus is named coronavirus disease 2019(COVID-19).COVID-19 may have a rapid and devastating course in some cases leading to severe complications and *** imaging methods have an invaluable role in diagnosis,follow-up,and *** this review,radiological imaging findings of COVID-19 have been systematically reviewed based on the published literature so *** reporting templates are also emphasized from a different point of view,considering specific distinctive patterns of involvement.

关键词： Coronavirus disease 2019 Severe acute respiratory syndrome coronavirus 2 Computed tomography Pneumonia Acute respiratory distress syndrome Ground-glass opacities Crazy-paving pattern

中药在增殖性糖尿病视网膜病变玻璃体切割术围手术期应用的研究进展

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中国中医眼科杂志 2022年第5期32卷 404-407页

作者：高明雪严京马若楠吴正正中国中医科学院眼科医院北京100040

玻璃体切割术是增殖性糖尿病视网膜病变(PDR)的明确有效的重要治疗手段,给患者复明带来了希望,但术后仍存在玻璃体再出血、黄斑水肿等并发症。中药在玻璃体切割术围手术期能够起到止血、减轻水肿,促进出血吸收等作用,术前用药可减少术... 详细信息

玻璃体切割术是增殖性糖尿病视网膜病变(PDR)的明确有效的重要治疗手段,给患者复明带来了希望,但术后仍存在玻璃体再出血、黄斑水肿等并发症。中药在玻璃体切割术围手术期能够起到止血、减轻水肿,促进出血吸收等作用,术前用药可减少术中玻璃体出血,提高手术成功率;术后用药可减少术后并发症,提高术后视功能。临床术前大多采用凉血止血中药以防止术中玻璃体出血,术后大多采用凉血止血、活血化瘀、益气养阴中药治疗玻璃体再出血,采用活血利水、益气养阴中药治疗术后黄斑水肿。本文综述了近10年中药在PDR玻璃体切割术围手术期临床应用进展,以期发挥中医药优势,为临床治疗提供借鉴。

关键词：中药玻璃体切割术增殖性糖尿病视网膜病变围手术期

Evaluation （POE） of Yildiz Technical University （YTU） School of Foreign Languages （SFL）

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Journal of Civil Engineering and Architecture 2012年第9期6卷 1128-1137页

作者： Muzaffer Tolga Akbulut Cigdem Polatoglu Ayfer aytug Faculty of Architecture Yildiz Technical University Besiktas 34 349 Istanbul Turkey

Impact of adjuvant treatment modalities on survival outcomes in curatively resected pancreatic and periampullary adenocarcinoma

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Chinese Journal of Cancer Research 2015年第4期27卷 408-416页

作者： Nedim Turan Mustafa Benekli Olcun Umit Unal ?lkay Tugba Unek Didem Tastekin Faysal Dane Efnan Alg?n Sukran Ulger Tulay Eren Turkan Ozturk Topcu Esma Turkmen Nalan Akgül Babacan Gulnihal Tufan Zuhat Urakci Basak Oven Ustaalioglu Ozlem Sonmez Uysal Ozlem Balvan Ercelep Burcu Yapar Taskoylu Asude Aksoy Mustafa Canhoroz Umut Demirci Erkan Dogan Veli Berk Ozan Balakan Ahmet ?iyar Ekinci Mukremin Uysal ?brahim Petekkaya Sel?uk Cemil Ozturk ?nder Tonyal? Bülent ?etin Mehmet Naci Aldemir Kaan Helvac? Nuriye Ozdemir ?lhan Oztop Ugur Coskun aytug Uner Ahmet Ozet Suleyman Buyukberber Department of Medical Oncology Faculty of Medicine Cumhuriyet University Department of Medical Oncology Faculty of Medicine Gazi University Department of Medical Oncology Faculty of Medicine Dokuz Eylul University Department of Medical Oncology Faculty of Medicine Necmettin Erbakan University Department of Medical Oncology Faculty of Medicine Marmara University Department of Radiation Oncology Faculty of Medicine Gazi University Department of Medical Oncology Numune Education and Research Hospital Department of Medical Oncology Faculty of Medicine Karadeniz Technical University Department of Medical Oncology Faculty of Medicine Trakya University Department of Medical Oncology Rize Education and Research Hospital Department of Medical Oncology Faculty of Medicine Dicle University Department of Medical Oncology Dr.Lutfi Kirdar Kartal Education and Research Hospital Department of Medical Oncology Sakarya Education and Research Hospital Department of Medical Oncology Faculty of Medicine Pamukkale University Department of Medical Oncology Faculty of Medicine Inonu University Department of Medical Oncology Faculty of Medicine Firat University Department of Medical Oncology Dr.Abdurrahman Yurtaslan Education and Research Hospital Department of Medical Oncology Faculty of Medicine Yuzuncu Yil University Department of Medical Oncology Faculty of Medicine Erciyes University Department of Medical Oncology Faculty of Medicine Sutcu Imam University Department of Medical Oncology Diyarbakir Education and Research Hospital Department of Medical Oncology Faculty of Medicine Kocatepe University Department of Medical Oncology Dr.Ersin Arslan State Hospital Department of Medical Oncology Education and Research Hospital Ad?yaman University Department of Medical Oncology Faculty of Medicine Mustafa Kemal University Department of Medical Oncology Faculty of Medicine Ataturk University

Background： We examined the impact of adjuvant modalities on resected pancreatic and periampullary adenocarcinoma（PAC）.Methods： A total of 563 patients who were curatively resected for PAC were retrospectively analyzed between 2003 and ***： Of 563 patients, 472 received adjuvant chemotherapy（CT） alone, chemoradiotherapy（CRT） alone, and chemoradiotherapy plus chemotherapy（CRT-CT） were analyzed. Of the 472 patients, 231 were given CRT-CT, 26 were given CRT, and 215 were given CT. The median recurrence-free survival（RFS） and overall survival（OS） were 12 and 19 months, respectively. When CT and CRT-CT groups were compared, there was no significant difference with respect to both RFS and OS, and also there was no difference in RFS and OS among CRT-CT, CT and CRT groups. To further investigate the impact of radiation on subgroups, patients were stratified according to lymph node status and resection margins. In node-positive patients, both RFS and OS were significantly longer in CRT-CT than CT. In contrast, there was no significant differencebetween groups when patients with node-negative disease or patients with or without positive surgical margins were ***： Addition of radiation to CT has a survival benefit in patients with node-positive disease following pancreatic resection.

关键词： Pancreatic adenocarcinoma adjuvant chemotherapy(adjuvant CT) adjuvant radiotherapy

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生态文明理论和江苏的生态文明建设

污染防治技术 2012年第6期25卷 64-66页

作者：周永艳包晓男江苏省环境科学研究院

论述了生态文明理论的内涵及其特点,介绍了国内生态文明建设理论的应用,并归纳出中国生态文明建设的鲜明特点,即以生态省(市、县)建设为抓手,依托有形的载体扎实推进生态文明建设。结合江苏省可持续发展的战略,提出江苏生态文明建设的... 详细信息

论述了生态文明理论的内涵及其特点,介绍了国内生态文明建设理论的应用,并归纳出中国生态文明建设的鲜明特点,即以生态省(市、县)建设为抓手,依托有形的载体扎实推进生态文明建设。结合江苏省可持续发展的战略,提出江苏生态文明建设的实现途径,以生态省建设为载体加快推进生态文明建设,努力走出一条经济发展与环境保护双赢的可持续发展之路。

关键词：生态文明科学发展生态环境

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妊娠期处女膜自发性闭锁

世界核心医学期刊文摘（妇产科学分册） 2006年第1期2卷 9-9页

作者： onan M. A. Turp A. B. Taskiran C. 郭培奋(译) 李奎(校) Dr. M.A. onan Gazi University Faculty of Medicine Department of Obstetrics and Gynecology Besevler Ankara Turkey 不详

Imperforate hymen is a rare disorder that is usually discovered at the onset of menstruation. In the literature, secondary closure of the hymen has been reported in 2 cases, both of which occurred subsequent to surgical procedures that involved the hymen. We report an interesting case of the spontaneous formation of an imperforate hymen during pregnancy in the absence of previous surgical procedures. Electron microscopic findings indicate hymenal tissue reorganization.

关键词：处女膜闭锁自发性妊娠期电子显微镜月经初潮组织发生继发性手术后手术史检查表