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Primary hyperparathyroidism-induced acute pancreatitis in pregnancy:A systematic review with a diagnostic-treatment algorithm

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World Journal of Gastroenterology 2024年第32期30卷 3755-3765页

作者： Goran augustin Quirino Lai Maja Cigrovski Berkovic Department of Surgery University Hospital Centre Zagreb and School of Medicine University of ZagrebZagreb 10000Croatia General Surgery and Organ Transplantation Unit Department of SurgerySapienza University of RomeRome 00018Italy Department for Sport and Exercise Medicine Faculty of KinesiologyUniversity of ZagrebZagreb 10000Croatia

BACKGROUND Primary hyperparathyroidism(PHPT)-induced acute pancreatitis(AP)during pregnancy has rarely been *** to this rarity,there are no diagnostic or treatment algorithms for pregnant *** To determine appropriate diagnostic methods,therapeutic options,and factors related to maternal and fetal outcomes for PHPT-induced AP in *** A literature search of articles in English,Japanese,German,Spanish,and Italian was performed using PubMed(1946-2023),PubMed Central(1900-2023),and Google *** Preferred Reporting Items for Systematic reviews and Meta-Analyses(PRISMA)protocol was *** search terms included“pancreatite acuta,”“iperparatiroidismo primario,”“gravidanza,”“travaglio,”“puerperio,”“postpartum,”“akute pankreatitis,”“primärer hyperparathyreoidismus,”“Schwangerschaft,”“Wehen,”“Wochenbett,”“pancreatitis aguda,”“hiperparatiroidismo primario,”“embarazo,”“parto,”“puerperio,”“posparto,”“acute pancreatitis,”“primary hyperparathyroidism,”“pregnancy,”“labor,”“puerperium,”and“postpartum.”Additional studies were identified by reviewing the reference lists of retrieved ***,imaging,surgical,obstetric,and outcome data were *** Fifty-four cases were collected from the 51 *** median maternal age was 29 ***-induced AP starts at the 20th gestational week;higher gestational weeks were seen in mothers who died(mean gestational week 28).Median values of amylase(1399,Q1-Q3=519-2072),lipase(2072,Q1-Q3=893-2804),serum calcium(3.5,Q1-Q3=3.1-3.9),and parathormone(PTH)(384,Q1-Q3=123-910)were *** 46 cases,adenoma was the cause of PHPT,followed by 2 cases of carcinoma and 1 case of *** the remaining 5 cases,the diagnosis was not *** ultrasound was positive in 34 cases,whereas sestamibi was performed in 3 cases,and neck computed tomography or magnetic resonance imaging was performed in 9 cases(the enlarged parathyroid gland was not localized in 3 cases).Surgery was the prefer

关键词： Primary hyperparathyroidism Acute pancreatitis Pregnancy Diagnosis Maternal mortality Fetal mortality Algorithm

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Evaluation of the Efficacy of an Aloe barbadensis Based Biological Insecticide against Pests of Abelmochus esculentus for Promoting Ecological Agriculture (Far-North, Cameroon)

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Agricultural Sciences 2024年第5期15卷 590-603页

作者： Mba Félicité Obono Laurentine Naoutissa Samuel Ntamack augustin Goudoum Department of Environmental Science National Advanced School of Engineering The University of Maroua Maroua Cameroon Department of Agriculture Livestock and Derived Products National Advanced School of Engineering The University of Maroua Maroua Cameroon

Chemical insecticides have been considered as a means to combat crop pests. Although their effectiveness is evident, their impact on the environment is increasingly being discussed. The aim of this study is to determine the agro-ecological potential of a biological insecticide (C25H32O12) based on Aloe barbadensis in a Sahelian context. For this purpose, a completely randomized block experimental design with 3 replications and 4 treatments was set up to experiment with Aloe barbadensis as a bioinsecticide against pests of Abelmoschus esculentus. However, data were collected using an observation and parameter monitoring grid. This includes the cultivation of Abelmoschus esculentus, soil preparation, seeding and watering, plot labeling, preparation of the bioinsecticide (selection and preparation of raw materials, grinding of Aloe barbadensis miller and extraction of the crude bioinsecticide, quantification of treatment doses and dilution, and obtaining the formulated bioinsecticide), plant watering, plant treatment, and finally parameter monitoring. The results obtained reveal that the level of damage is significantly high in the control treatment T0 (63%) compared to the other treatments, with 29% for treatment T1, 7% for T2, and 1% for T3, implying a strong action capability of this insecticide against pests of Abelmoschus esculentus. Therefore, it can be concluded that for a normal growing season of Abelmoschus esculentus, this biological insecticide should be sprayed 12 times. Furthermore, this biological insecticide is unique in that it does not inflict any gastric toxicity on the pests, which gives it the characteristic of being a repellent. It is a biological insecticide whose efficacy period has been tested, with a minimum duration of 21 days. In conclusion, this formulated bioinsecticide based on Aloe barbadensis demonstrates significant efficacy against pests of Abelmoschus esculentus. In the future, we will consider experim

关键词： Aloe Biological Insecticide Pests Agro-Ecological

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Study of Factors Associated with the Practice of Vaccination against COVID-19 among Medical Science Students in Dakar (Senegal)

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Open Journal of Epidemiology 2024年第2期14卷 199-220页

作者： Chafika Ibrahim Zanguina Theresa Stella Esperance Fouckou Moko Jean augustin Diegane Tine Department of Medicine El Hadji Ibrahima Niasse University of Dakar Dakar Senegal Department of Preventive Medicine and Public Health Faculty of Medicine Pharmacy and Odontology Cheikh Anta Diop University Dakar Senegal

Introduction: Almost a year after the start of the COVID-19 pandemic, Senegal embarked on a vaccination campaign to protect its population. The objective of this study was to identify the factors influencing the COVID-19 vaccination practices within a health training university in Dakar. Methodology: This was a cross-sectional, descriptive and analytical study carried out from October 21 2021 to February 21 2022 among students at the Elhadj Ibrahima Niass private University in Dakar, Senegal. A 28-question online questionnaire was sent to all students enrolled at the university during this period. Results: Of the 576 students who responded, the average age was 22.60 years, with females predominating (57.81%). Medical students accounted for 66.14% of participants, pharmacy 22.40% and dental surgery 11.46%. Of these, 42.01% were bachelor’s students, 29.51% master’s students and 28.47% doctoral students. Vaccination coverage was 50.35%. Students who considered COVID-19 to be very dangerous were more likely to be vaccinated (OR = 5.05 [2.24-11.9]). Those with poor knowledge of vaccines were less likely to be vaccinated (OR = 0.07 [0.03-0.18]), as were those with poor knowledge of contraindications to vaccination (OR = 0.49 [0.28-0.86]). No association was found between vaccination status and socio-demographic or educational characteristics. Conclusion: In view of the importance of knowledge about COVID-19 vaccination, our results suggest that it is important to involve health students in the Ministry of Health’s awareness-raising strategies, because their support is necessary for better public awareness.

关键词： COVID-19 Vaccination Health Students Senegal

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The Role of Music Therapy in Supporting Intellectually Disabled Youth in Senegal

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Health 2024年第5期16卷 521-534页

作者： Raymond Birane Youm Kadidiatou Diarra Mathias Pouye Jean augustin Diégane Tine National School of Arts (ENA) Dakar Senegal EDSEV in Cheikh Anta Diop University (UCAD) Dakar Senegal ISED in Cheikh Anta Diop University (UCAD) Dakar Senegal

Introduction: Music therapy is a practice for helping and supporting people with intellectual and relational difficulties. This study illustrated the benefits of music therapy for young people living with intellectual disabilities (YLID) in an African context. Methodology: This study investigated six young individuals with intellectual disabilities who had undergone three years of music therapy. They were participants in the inclusive non-academic training program at the National School of Arts in Dakar from 2017 to 2019. Data collection utilized individual interviews with the youths, evaluation grids from teachers and psychiatrists. Guardians provided informed consent along with the assent of the young participants. Results: The six young were aged between 18 and 30 years old, with an average age of 24.6 years. Four of the YLID were male. Three young people with intellectual disabilities had delayed psychomotor development. Observations revealed the beneficial influence of music therapy on the health and well-being of young individuals. Music played a role in alleviating stress and anxiety among youth with intellectual disabilities (YLID), enhancing their mood and mental health. It assisted in navigating challenging situations and heightened alertness among YLID. Additionally, music therapy contributed to improvements in dyslexia, fine and gross motor skills, and memory development among intellectually disabled youth, ultimately facilitating their integration into society. Conclusion: In light of our results, music therapy makes a major contribution to the empowerment of YLID. Engaging in musical activities helps young people connect with others through instrumental expression and a sense of accomplishment. By facilitating music therapy, it becomes possible to combat discrimination and stigmatization, thus promoting the social inclusion of intellectually disabled youth. Therefore, it is important to promote music therapy in Senegal to meet the needs of YLID.

关键词： Music Therapy Young Intellectual Disabilities Senegal

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Physicochemical Characterisation of Flours from Local Cereals and Powder from Cassava (Manihot esculenta Crantz) Leaves Varieties Cultivated in the Northern-Cameroon in Order to Supplement Infant Flours

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Open Journal of Applied Sciences 2024年第8期14卷 2009-2026页

作者： Mathieu Barbi Charles Touwang Emmanuel Panyoo Akdowa augustin Goudoum Armand Abdou Bouba Department of Agriculture Livestock and Derivated Products National Advanced School of Engineering University of Maroua Maroua Cameroon Institute of Agricultural Research for Development (IRAD) Food Technology and Post-Harvest Laboratory of Garoua Garoua Cameroon Department of Food Sciences and Nutrition National Advanced School of Agro-Process Industries University of Ngaoundr Ngaoundr Cameroon

The aim of the present study was to investigate on the inventory and determination of the nutritional value of cereals flour and cassava leaves powder in order to analyse their use in the production of infant flour. In this paper, a A survey to identify the cereals used in the preparation of infant porridge in the Northern Cameroon was done by using 447 mothers having children between 06 and 59 months from areas (Gbakoungue, Sassa-Mbersi, Sanguere-Ngal and Kotkong-Wouldata) with high rate on malnourished children. Flour was prepared from the most preponderant cereals and Cassava leaves powder from varieties identified by the Regional Centre of Agricultural Research (CRRA) of Wakwa and local population. Flour and powder samples obtained were subjected to chemical composition analysis. Parameters analysed were crude proteins, total carbohydrates, ash, total fats, total phenols, total tannins, total carotenoids, vitamin C or cyanide. Also Iron, calcium and zinc were determined. The results revealed that white maize (62%) was the main cereal used in the preparation of infant porridge followed respectively by red sorghum, white rice and muskwari. Ten cassava varieties were identified: three (03) by CRRA (TME, 96/1/14 and IRAD 4115) and seven (south, gambada, sweet, Benin, six months, M. glaziovii and grouna) by local population. Amongst cereals flour, those from white maize indicated high protein (10.09%), carbohydrates (84.46%) and total fat (7.46%) contents. The powder from 96/14/14 cassava variety showed high amount of iron (11.98 mg/100g), calcium (751.02 g/100g) and low cyanide content (1.21 ppm) amongst all the cassava leaves powder samples. The supplementation of white maize flour by cassava leaves powder from 96/14/14 variety could therefore be recommended for the preparation of infant flours.

关键词： Infant Flour Cereals Flour Cassava Leaves Powder Chemical Composition Northern Cameroon

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Epidemiological Profile of Men Who Have Sex with Men: First Data about Male Sex Workers in Central African Republic (CAR)

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Advances in Sexual Medicine 2024年第1期14卷 1-11页

作者： Hermione Dahlia Mossoro-Kpinde bal.kouzou augustin Paola Julienne Demba Henri Saint Calvaire Diemer Direction de la Médecine du Travail Ministère du Travail de l’Emploi de la Protection Sociale et de la Formation Professionnelle Ban-gui République Centrafricaine Comité National de Lutte contre le Sida Bangui République Centrafricaine Faculté des Sciences de la Santé Université de Bangui Bangui République Centrafricaine Département de Santé Publique Faculté des Sciences de la Santé Université de Bangui Bangui République Centrafricaine

Objectives: Sex work is not well documented among African men. The aim of this study was to describe the epidemiological profile of men who have sex with men (MSM) and eventually to determine the proportion of sex workers (SW) among them, as well as the proportion of MSM who have been victims of gender-based violence (GBV). Material and Methods: A cross-sectional study coordinated by the Direction de la Médecine du Travail was carried out at the headquarters of the association ALTERNATIVES in Bangui Bangui from July 1 to October 31, 2021. Consenting MSM present during the study period were systematically included. Sociodemographic variables, those relating to the future vision of the activity and to GBV were collected and analyzed using Epi-Info version 7 software. Results: Forty MSM with an average age of 23 years and mainly secondary education (75.0%) were included. The vast majority of MSM were unemployed (85.0%). 45.0% had been victims of GBV and wanted to stop working as an MSM (47.5%), and almost 2/3 (65.0%) would accept another income-generating activity in exchange for the MSM. Violence was sexual (32.5%), economic (22.5%), physical (20.0%), verbal (12.5%) and psychological (12.5%). Conclusion: The MSM were mainly young, poorly educated, unemployed, and almost half were victims of GBV. The desire to change MSM activity to another income-generating activity alongside that of MSM shows that many of them are SW, workers in the informal sector. This must be taken into account in prevention activities, even if the data needs to be confirmed on a much larger sample.

关键词： Men Who Have Sex with Men Sex Workers Gender-Based Violence Informal Sector Central Africa

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Contribution of Metabolic Imaging in the Exploration of Cognitive Disorders Related to COVID-19

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Advances in Molecular Imaging 2024年第1期13卷 1-5页

作者： Serigne Moussa Badiane Amadou Barro Elhadji Amadou Lamine Bathily Louis augustin Diaga Diouf Biophysics and Nuclear Medicine Gaston Berger University Saint-Louis Senegal ENT Department Fann University Hospital Dakar Senegal Biophysics and Nuclear Medicine Cheikh Anta Diop University Dakar Senegal

On March 11, 2019, the WHO declared COVID-19 a pandemic disease. It is a respiratory tropism SARS COV 2 infection. In the emergency of the pandemic, in medical imaging, only computed tomography (CT) of the lungs was favored to assess lung lesions. In addition, many cases of post-COVID-19 cognitive disorders have been reported. As the curve dips and services restart correctly, other imaging techniques have been used to better explore the disease. The objective of this presentation is to illustrate the contribution of metabolic imaging in the exploration of post COVID-19 cognitive disorders and to discuss the pathophysiological mechanisms. Hypometabolism brain lesions are objective signs of functional impairment whose pathophysiological mechanism is not yet fully understood. Metabolic imaging with PET-SCAN is a suitable tool for exploring these disorders, both for the severity and extent of the lesions and for the topography of the brain damage.

关键词： COVID-19 Nuclear Medicine Cognitive Disorders PET-SCAN

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科特迪瓦传统饮食生活方式下的产品设计风格——以餐具为例

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创意与设计 2024年第4期 61-69页

作者： Pokou augustin Nelson 南京艺术学院国际教育学院

本文过论了科特迪瓦传统生活方式与当代产品设计之间的交集。它紧跟产品设计趋势,致力于通过创新产品的开发改善和丰富生活方式。通过审视科特迪瓦丰富的文化遗产,特别是饮食方式和相关物品,我们强调了将传统价值观和实践融入现代产品... 详细信息

本文过论了科特迪瓦传统生活方式与当代产品设计之间的交集。它紧跟产品设计趋势,致力于通过创新产品的开发改善和丰富生活方式。通过审视科特迪瓦丰富的文化遗产,特别是饮食方式和相关物品,我们强调了将传统价值观和实践融入现代产品设计过程的重要性。通过文化分析的结合,本文一方面强调了向基于非洲哲学和智慧的产品设计范式转变的必要性。另一方面,本文突出了拥抱土著知识以促进设计产业更健康发展的重要性,从而加强科特迪瓦文化在全球范围内的身份认同。

关键词：传统生活方式产品设计科特迪瓦文化科特迪瓦哲学

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Influence of Solvent onto Chemical Extraction of America-Type Coconut (Coco nucifera L.) Fbers: Analysis of Physicochemical, Mechanical and Morphological Properties

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Journal of Textile Science and Technology 2024年第3期10卷 64-81页

作者： Delphine Korgai Gandai Zara Haman Djoda Pagore Frederic Memtine Ndong augustin Abdourhamane Nsangou Niraka Blaise Hambate Gomdje Valery National Advanced School of Engineering of Maroua University of Maroua Maroua Cameroon School of Chemical Engineering and Mineral Industries University of Ngaoundere Ngaoundere Cameroon Department of Mechanical Engineering ENSET University of Douala Douala Cameroon

In this study, the natural fibers from Coconuts of the species Coco nucifera L. were Chemically extracted in different solvents such as sodium hydroxide (SH), acetone (AC) and sodium hydroxide-acetone (SHA) for their applications in the textile industries. Structural, morphological and physico-mechanical characterizations such as X-ray diffraction (XRD), Fourier transform infrared spectrometry (FTIR), scanned electron microscopy (SEM), measurements of density, Young’s modulus, water absorption rate and humidity were evaluated. The XRD and FTIR results show that Coco nucifera L. fibers contains type I cellulose. Mechanical characterizations were also carried out. These results show that by varying the different solvents used, the physico-chemical, mechanical and morphological properties of the fibers change, which implies that the solvent has an influence on the properties of these fibers. The fibers extracted by the sodium hydroxide-acetone mixture have a linear density of 1.636, the percentage of water absorption is 62.428%, the percentage of moisture absorption 9.605% compared to other values in the literature shows that this solvent mixture improves the properties of coconut fibers which contain type I cellulose. The tensile stress is 0.013 GPa, the percentage strain is 49.836% and the Young’s modulus is 0.114 GPa as well as the percentage elongation show that these fibers are elasto-plastic. The values obtained mean that these fibers are suitable for use in textiles.

关键词： Chemical Extraction Cellulose Coco nucifera L. Fibers Elasto-Plastic Textiles

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Eudragit^®-PEG Nanoparticles: Physicochemical Characterization and Interfacial Tension Measurements

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Open Journal of Biophysics 2024年第2期14卷 121-131页

作者： Papa Mady Sy Sidy Mouhamed Dieng Alphonse Rodrigue Djiboune Louis augustin Diaga Diouf Boucar Ndong Gora Mbaye Mounibé Diarra Laboratory of Physics and Pharmaceutical Biophysics Faculty of Medicine Pharmacy and Odontology UCAD Dakar Senegal Laboratory of Galenic Pharmacy Faculty of Medicine Pharmacy and Odontology UCAD Dakar Senegal Laboratory of Medical Biophysics and Nuclear Medicine Faculty of Medicine Pharmacy and Odontology UCAD Dakar Senegal

The objectives of this study are to understand the mechanisms involved in the stabilization of water/oil interfaces by polymeric nanoparticles (NPs) (Eudragit®). Eudragit L100 NPs of various sizes and Zeta potentials were studied and compared at a water/cyclohexane model interface using a droplet tensiometer (Tracker Teclis, Longessaigne, France). The progressive interfacial adsorption of the NPs in the aqueous phase was monitored by tensiometry. The model interface was maintained and observed in a drop tensiometer, analyzed via axisymmetric drop shape analysis (ADSA), to determine the interfacial properties. Given the direct relationship between the stability of Pickering emulsions (emulsions stabilized by solid nanoparticles) and the interfacial properties of these layers, different nanoparticle systems were compared. Specifically, Eudragit NPs of different sizes were examined. Moreover, the reduction of the Zeta potential with PEG-6000 induces partial aggregation of the NPs (referred to as NP flocs), significantly impacting the stability of the interfacial layer. Dynamic surface tension measurements indicate a significant decrease in interfacial tension with Eudragit® nanoparticles (NPs). This reduction correlates with the size of the NPs, highlighting that this parameter does not operate in isolation. Other factors, such as the contact angle and wettability of the nanoparticles, also play a critical role. Notably, larger NPs further diminished the interfacial tension. This study enhances our understanding of the stability of Pickering emulsions stabilized by Eudragit® L100 polymeric nanoparticles.

关键词： Nanoparticles Eudragit® PEG Interfacial Tension Pickering Emulsion

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