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下巴秘史

新发现 2016年第8期 74-78页

作者： aude Rambaud 陈雯洁

有下巴才算现代人！其他灵长目动物都没有下巴，为何单单人类会长下巴！让我们试着解开谜团……

关键词：下巴灵长目动物演化速度科学研究工作

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深层巩膜切除术后复发性—过性视力下降

美国医学会眼科杂志（中文版） 2002年第1期14卷 48-49页

作者： aude Ambresin 任泽钦等

Multi-scale high-throughput phenotyping of apple architectural and functional traits in orchard reveals genotypic variability under contrasted watering regimes

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Horticulture Research 2019年第1期6卷 1015-1029页

作者： aude Coupel-Ledru Benoit Pallas Magalie Delalande Frederic Boudon Emma Carrie Sebastien Martinez Jean-Luc Regnard Evelyne Costes UMR AGAP Univ MontpellierCIRADINRAMontpellier SupAgro34398 Montpellier Cedex 5France CIRAD 34398 Montpellier Cedex 5France University of Bristol School of Biological SciencesLife Science Building24 Tyndall AvenueBristol BS81TQUK

Despite previous reports on the genotypic variation of architectural and functional traits in fruit trees,phenotyping large populations in the field remains *** this study,we used high-throughput phenotyping methods on an apple tree core-collection(1000 individuals)grown under contrasted watering ***,architectural phenotyping was achieved using T-LiDAR scans for estimating convex and alpha hull volumes and the silhouette to total leaf area ratio(STAR).Second,a semi-empirical index(IPL)was computed from chlorophyll fluorescence measurements,as a proxy for leaf ***,thermal infrared and multispectral airborne imaging was used for computing canopy temperature variations,water deficit,and vegetation *** traits estimated by these methods were compared to low-throughput in planta *** indices and alpha hull volumes were significantly correlated with tree leaf area and trunk cross sectional area,while IPL values showed strong correlations with photosynthesis measurements collected on an independent leaf *** contrast,correlations between stomatal conductance and canopy temperature estimated from airborne images were lower,emphasizing discrepancies across measurement *** heritability values were obtained for almost all the traits except leaf photosynthesis,likely due to large intra-tree *** means were used in a clustering procedure that defined six classes of architectural and functional *** between groups showed several combinations between architectural and functional traits,suggesting independent genetic *** study demonstrates the feasibility and relevance of combining multi-scale high-throughput methods and paves the way to explore the genetic bases of architectural and functional variations in woody crops in field conditions.

关键词： architectural traits functional

Deciphering the Role of Klf10 in the Cerebellum

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Journal of Biomedical Science and Engineering 2022年第5期15卷 140-156页

作者： Malek Kammoun Lydie Nadal-Desbarats Sandra Même aude Lafoux Corinne Huchet Géraldine Meyer-Dilhet Julien Courchet Frédéric Montigny Frédéric Szeremeta William Même Vladimir Veksler Jérôme Piquereau Philippe Pouletaut Malayannan Subramaniam John R. Hawse Jean-Marc Constans Sabine F. Bensamoun Biomechanics and Bioengineering CNRS UMR 7338 Sorbonne University—University of Technology of Compiègne Compiègne France iBrain CNRS UMR 1253 University of Tours Tours France Center for Molecular Biophysics CNRS UPR4301 Orléans France Therassay Platform University of Nantes Nantes France INSERM UMR1089 University of Nantes Nantes France CNRS UMR-5310 and INSERM U-1217 NeuroMyoGène Institute Villeurbanne France INSERM PST-ASB University of Tours Tours France INSERM UMR-S 1180 University of Paris-Saclay Chatenay-Malabry France Department of Biochemistry and Molecular Biology Mayo Clinic Rochester USA CHIMERE EA7516 UPJV Faire Faces Institute Amiens France

Recent studies have demonstrated a new role for Klf10, a Krüppel-like transcription factor, in skeletal muscle, specifically relating to mitochondrial function. Thus, it was of interest to analyze additional tissues that are highly reliant on optimal mitochondrial function such as the cerebellum and to decipher the role of Klf10 in the functional and structural properties of this brain region. In vivo (magnetic resonance imaging and localized spectroscopy, behavior analysis) and in vitro (histology, spectroscopy analysis, enzymatic activity) techniques were applied to comprehensively assess the cerebellum of wild type (WT) and Klf10 knockout (KO) mice. Histology analysis and assessment of locomotion revealed no significant difference in Klf10 KO mice. Diffusion and texture results obtained using MRI revealed structural changes in KO mice characterized as defects in the organization of axons. These modifications may be explained by differences in the levels of specific metabolites (myo-inositol, lactate) within the KO cerebellum. Loss of Klf10 expression also led to changes in mitochondrial activity as reflected by a significant increase in the activity of citrate synthase, complexes I and IV. In summary, this study has provided evidence that Klf10 plays an important role in energy production and mitochondrial function in the cerebellum.

关键词： Klf10 Cerebellum Mice Magnetic Resonance Imaging and Spectroscopy Metabolomics Mitochondria

Complications of Peripartum Cardiomyopathy at the Departmental University Hospital Teaching of Borgou (Benin) in 2022: About 3 Cases

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World Journal of Cardiovascular Diseases 2022年第11期12卷 514-526页

作者： Léopold Houétondji Codjo Serge Hugues Mahougnon Dohou Sèdjro Raoul Atade Fabrice Atika Hamondji Nicolas Amegan Chabi Olaniran Alphonse Biaou Kayivi Murielle Hounkponou Djidjoho Arnaud Sonou Mahouna Philippe Adjagba Marielle Dorine Soude Dominique Sacca Mèdéssè Rolande Quenum aude Sourou Bodjrenou Martin Dèdonougbo Houenassi Cardiology Teaching and Research Unit (CNHU-HKM) Faculty of Health Sciences University of Abomey Calavi Cotonou Benin Teaching and Research Unit in Cardiology (CHUD-B/A) Faculty of Medicine University of Parakou Parakou Benin Teaching and Research Department of Gynecology and Obstetric (CHUD-B/A) Faculty of Medicine University of Parakou Parakou Benin Doctoral School of Health Sciences University of Abomey Calavi Cotonou Benin Regional Institute of Public Health University of Abomey Calavi Cotonou Benin Cardiology Teaching and 6 Research Unit (CHU-MEL) Faculty of Health Sciences University of Abomey Calavi Cotonou Benin Cardiology Department of Atacora-Donga Department Hospital Center (CHD-A/D) Natitingou Benin Teaching and Research Unit in Cardiology Faculty of Medicine (CHU-OP) University of Abomey Calavi Cotonou Benin

Introduction: Peripartum cardiomyopathy (PPCM) is a dilated cardiomyopathy occurring in the last month of pregnancy or the first five months postpartum without pre-existing cardiovascular pathology. It is a major cause of pregnancy-related heart failure with high morbidity and mortality. In severe forms (10% to 15% of cases), thrombo-embolic complications are the main cause. The initial hemodynamic evolution is totally unpredictable and sometimes extremely brutal and fatal. The objective of this work was to show the often pejorative evolution of PPCM in our country. Methods: We report in this work three serious clinical cases revealing the complications of this PPCM among patients admitted to the cardiology department of the CHUD-B/A in 2022 for heart failure. The data were collected according to the Declaration of Helsinki. Patients and Observations: The first case was a PPCM with severe left ventricular (LV) systolic dysfunction complicated by spontaneous left intraventricular contrast and right superficial sylvian ischemic stroke. The second case reports a global cardiac decompensation of a PPCM with severe LV systolic dysfunction complicated by an apical thrombus. The third case is that of a state of cardiogenic shock complicating a PPCM with severe LV systolic dysfunction. Among our 03 patients presenting these severe forms of PPCM, the evolution, in spite of the symptomatic and prognostic treatments of the heart failure, and even of the complications, was unfavourable with death in two of them. Conclusion: Complications of PPCM are frequent and fatal in Benin.

关键词： Cardiomyopathy Peripartum Complications Parakou Benin

福斯厂炼钢车间CAS—OB工艺的理率与初步操作结果

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国外钢铁 1990年第10期15卷 30-34页

作者： aude.,S. 崔树芳

孩子们不允许我们绝望玛丽-奥德·缪莱尔在2023年法兰克福书展上的演讲

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阅读与成才 2023年第5期 113-114页

作者：玛丽-奥德·缪莱尔奇想国(翻译整理) 奇想国

在法国文化中心图书办公室为德国学生举办的展览中,有我为年轻人写的第四本书《轻松学荷兰语》(Le Hollandais sans peine)。这本书讲的是一个法国小男孩学习荷兰语的故事:小男孩和父母一起在德国的露营地度假,但令他父亲失望的是,他完... 详细信息

在法国文化中心图书办公室为德国学生举办的展览中,有我为年轻人写的第四本书《轻松学荷兰语》(Le Hollandais sans peine)。这本书讲的是一个法国小男孩学习荷兰语的故事:小男孩和父母一起在德国的露营地度假,但令他父亲失望的是,他完全拒绝学习德语。为了使父亲高兴——也多亏了他在露营地认识的一个朋友——小男孩假装学习荷兰语。

关键词：法兰克福书展露营地小男孩德国年轻人

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南通圆融华润西地块概念方案设计

建筑与文化 2015年第5期 33-35页

作者： Bolei Zhou Liu Liu aude Oliva Antonio Torralba Massachusetts Institute of Technology

位置中国江苏省面积20000平方米设计时间2012-2013年本地块是一个在今天看来,非常具有典型性的城市商业＂飞地＂：被商业巨鳄的超大体量MALL挤在城市快速路的路口一隅,面积亦不大。开发商对于是否有取地价值,是否具有运营盈利前景有犹... 详细信息

位置中国江苏省面积20000平方米设计时间2012-2013年本地块是一个在今天看来,非常具有典型性的城市商业＂飞地＂：被商业巨鳄的超大体量MALL挤在城市快速路的路口一隅,面积亦不大。开发商对于是否有取地价值,是否具有运营盈利前景有犹豫。在2014年的这个取地方案中,我们提出了自己的情景型商业的理解。

关键词：城市快速路城市商业中国江苏省动线盈利前景设计时间圆融体量 “飞地” 方案设计