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Health 2022年第2期14卷 236-245页

作者： Nozomu Mandai Jun sato Mayumi Watanabe Aki Ibe Simon R. Downes Hiroyuki Umiyama atsuko Uchinuno Faculty of Nursing Science Tsuruga Nursing University Tsuruga Japan Ibaraki Prefectural University of Health Sciences Ibaraki Japan Kansai University of Health Sciences Osaka Japan Faculty of Science and Engineering Chuo University Tokyo Japan Avalon University School of Medicine Willemstad Cura&#231 ao

Background: Happiness varies across the life course in a U shape, with the least happiness in mid-life during the working years. Therefore, choosing a career may be an important factor in life’s happiness. However, the relationship between the career selection process and happiness remains unclear. Methods: We surveyed 805 schoolteachers, office workers, and nurses from an available marketing database using an ad hoc questionnaire assessing happiness and career selection type. Results and Discussion: We found that happiness was significantly greater among schoolteachers and nurses than for office workers in Japan. Furthermore, among schoolteachers and office workers, an evasive/avoidance type of career-selection process had an unfavorable effect on happiness. However, among nurses, no such association was observed. Conclusion: Paying attention to the career-selection process may be helpful to improve happiness.

关键词： Happiness Career Selection Nursing Teaching Survey

Dehydrogenation of n-Butane to Butenes and 1,3-Butadiene over PtAg/Al2O3Catalysts in the Presence of H2

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Journal of Materials Science and Chemical Engineering 2018年第7期6卷 16-24页

作者： Hideki Kurokawa Hayato Namoto atsuko Horinouchi Mitsuhiko sato Mitsuki Usui Hitoshi Ogihara Hiroshi Miura Graduate School of Science & Engineering Saitama University Saitama Japan

The Al2O3-supported PtAg catalysts were prepared and evaluated for the dehydrogenation of n-butane at 550°C in the presence of H2. The PtAg/Al2O3 catalyst prepared by an impregnation method using the Cl- removing Pt/Al2O3 and AgNO3 showed a higher activity and selectivity to butenes and 1,3-butadiene compared to the Pt/Al2O3 catalyst, but a large amount of coke (about 30 wt% versus the catalyst weight) was formed during the dehydrogenation. The free Ag metal on the prepared catalyst dramatically promoted the coke formation, because the dehydrogenation of 1-butene over the Ag/Al2O3 catalyst produced a large amount of coke. The Cl- addition to the Cl- free Pt/Al2O3 catalyst decreased the coke formation by the reaction of the free Ag particles and Cl to form AgCl which was inactive for the coke formation. The highest initial conversion (50.3%) was obtained with the selectivity to butenes and 1,3-butadiene (butenes = 80.2% and 1,3-butadiene = 5.9%) when the PtAg/Al2O3 catalyst modified with Cl- was used.

关键词： PtAg Simple Dehydrogenation Coke Formation 1-Butene 2-Butene

Simplifying Laparoscopic Surgery for Left Side Colon and Rectal Cancer Using Linear Stapler for Vascular Ligation: A Prospective Cohort Study

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Journal of Cancer Therapy 2017年第4期8卷 341-348页

作者： Masanori Naito Takeo sato Takatoshi Nakamura Takahiro Yamanashi Hirohisa Miura atsuko Tsutsui Masahiko Watanabe Department of Surgery School of Medicine Kitasato University Sagamihara Japan

Introduction: Systematic lymphadenectomy and ligation of the feeding artery is extremely important when performing radical resection in colorectal cancer. However, vascular surgery via laparoscopy requires advanced skills and techniques;thus, this procedure needs to be simplified while maintaining quality of the surgery to make it a preferred technique for the surgeons. Methods: There were 49 patients who underwent laparoscopic sigmoidectomy or anterior resection till T2 level for sigmoid colon cancer and recto-sigmoid colon cancer. We analyzed short-term and long-term outcomes between stapling ligation and clipping ligation techniques used in these surgeries. Results: The mean volume of blood loss in the stapling ligation group was 12.8 ± 12.3 ml, which was significantly lower than 41.9 ± 71.2 ml of mean volume of blood loss in the clipping ligation group. There was no significant difference in the mean duration of surgery, the mean number of harvested lymph nodes, morbidity, recurrence, and 5-year relapse free survival rates between the 2 groups. Conclusions: This study demonstrates a surgical technique using staplers for vascular treatment of tumor-feeding arteries as a new technical improvement in laparoscopic colectomy for the treatment of early-stage colon cancer. We found that the described procedure was technically safe, simple, convenient, and oncologically valid.

关键词： Laparoscopic Surgery Colorectal Cancer Vascular Ligation Linear Stapler

Analysis of Residual Solvents in Annatto Extracts Using a Static Headspace Gas Chromatography Method

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American Journal of Analytical Chemistry 2012年第9期3卷 638-645页

作者： Yusai Ito Kyoko Ishizuki Wakana Sekiguchi atsuko Tada Takumi Akiyama Kyoko sato Takeshi Yamazaki Hiroshi Akiyama Division of Food Additives National Institute of Health Sciences: Kamiyoga Setagaya-ku Tokyo Japan

An analytical method for the quantification of residual solvents in annatto extracts, natural food colorants, was established using a static headspace gas chromatography (HSGC) coupled with a flame ionization detector (FID). As a sample diluent in a headspace sampling, dimethylformamide (DMF) was selected owing to its high capacity for dissolving both bixin-based and norbixin-based annatto extracts. The quantification of residual solvents was performed using the external standard method. The linearity of the calibration curves was assured with relative coefficients (R2) that were greater than 0.999. The recoveries of all standard solvents spiked in the annatto extracts were in the range from 95.1% to 107.1% to verify the accuracy and the relative standard deviation (RSD%) values (n = 3) were in the range from 0.57% to 3.31%. The quantification limits (QL) were sufficiently lower than the limits specified by Joint FAO/WHO Expert Committee on Food Additives (JECFA). With the established HSGC method, six residual solvents (methanol, ethanol, 2-propanol, acetone, ethyl acetate, and hexane) in 23 commercial annatto-extract products that consist of seven bixin-based and 16 norbixin-based products were quantified. The levels of residual ethyl acetate and hexane in all products were lower than the specified limits of JECFA. However, three samples of bixin-based products showed higher levels of residual 2-propanol (approximately 313.9 - 427.7 ppm) than the specified limit. Other bixin products also showed higher concentrations of residual methanol (approximately 166.6 - 394.7 ppm) and residual acetone (approximately 75.2 - 179.8 ppm) than the limits of JECFA. In the case of norbixin-based products, nine samples showed higher levels of residual acetone (approximately 42.6 - 139.5 ppm) than the limits of JECFA. This is the first survey of residual solvents in annatto extracts using the validated HSGC method.

关键词： Annatto Extracts Bixin Norbixin Headspace Gas Chromatography Residual Solvents