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Treatment of portosystemic shunt-borne hepatic encephalopathy in a 97-year-old woman using balloon-occluded retrograde transvenous obliteration:A case report

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World Journal of Clinical Cases 2023年第4期11卷 945-951页

作者： Akihiro Nishi Tsuneaki Kenzaka Misa Sogi Shuichiro Nakaminato Takahiro suzuki General Medicine Awa Regional Medical CenterTateyama 2940014ChibaJapan Division of Community Medicine and Career Development Kobe University Graduate School of MedicineKobe 6500017HyogoJapan Department of Radiology Kameda Medical CenterKamogawa 2968602ChibaJapan

BACKGROUND Hyperammonemia and hepatic encephalopathy are common in patients with portosystemic *** shunt occlusion has been standard treatment,although recently the less invasive balloon-occluded retrograde transvenous obliteration(B-RTO)has gained increasing *** far,there have been no reports on the treatment of portosystemic shunts with B-RTO in patients aged over 90 *** this study,we present a case of hepatic encephalopathy caused by shunting of the left common iliac and inferior mesenteric veins,successfully treated with *** SUMMARY A 97-year-old woman with no history of liver disease was admitted to our hospital because of disturbance of *** had no jaundice,spider angioma,palmar erythema,hepatosplenomegaly,or *** blood tests showed hyperammonemia,and abdominal contrast-enhanced computed tomography revealed a portosystemic shunt running between the left common iliac vein and the inferior mesenteric *** was diagnosed with hepatic encephalopathy secondary to a portosystemic *** patient did not improve with conservative treatment:Lactulose,rifaximin,and a low-protein diet.B-RTO was performed,which resulted in shunt closure and improvement in hyperammonemia and disturbance of ***,there was no abdominal pain or elevated levels of liver enzymes due to *** patient was discharged without further consciousness *** Portosystemic shunt-borne hepatic encephalopathy must be considered in the differential diagnosis for consciousness disturbance,including abnormal behavior and speech.

关键词： Hepatic encephalopathy Hyperammonemia Portosystemic shunt Balloon-occluded retrograde transvenous obliteration Elderly Case report

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Obstructive and secretory complications of diverting ileostomy

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World Journal of Gastroenterology 2022年第47期28卷 6732-6742页

作者： Shingo Tsujinaka Hideyuki suzuki Tomoya Miura Yoshihiro Sato Chikashi Shibata Department of Gastroenterological Surgery Tohoku Medical and Pharmaceutical UniversitySendai 983-8536MiyagiJapan

This review aimed to highlight the etiology,diagnosis,treatment,and prevention of obstructive and secretory complications associated with diverting ileostomy(DI).Obstructive complications at the stoma site are termed stoma outlet obstruction(SOO)or stoma-related obstruction(SRO).The incidence of SOO/SRO is 5.4%-27.3%,and the risk factors are multifactorial;however,the configuration of the stoma limb and the thickness of the rectus abdominis muscle(RAM)may be of particular ***-stomal tube decompression is initially attempted with a success rate of 33%-86%.A thick RAM may carry the risk of *** refinement,including a wider incision of the anterior sheath and adequate stoma limb length,avoids tension and immobility and may decrease SOO/*** complications of DI are termed high output stoma(HOS).Persistent HOS lead to water and sodium depletion,and secondary hyperaldosteronism,resulting in electrolyte imbalances,such as *** incidence of HOS is 14%-24%,with an output of 1000-2000 mL/d lasting up to three *** of HOS is commenced after excluding postoperative complications or enteritis and includes fluid intake restriction,antimotility and antisecretory drug therapies,and magnesium *** monitoring and surveillance programs have been successful in decreasing readmissions for dehydration.

关键词： Small bowel obstruction Stoma outlet obstruction Stoma-related obstruction High output stoma High output syndrome Dehydration

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Ketone bodies and inflammation modulation:A mini-review on ketogenic diet’s potential mechanisms in mood disorders

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BIOCELL 2023年第8期47卷 1897-1906页

作者： YAN ZHENG SIHUI MA KATSUHIKO suzuki HISANORI KATO HUIJUAN JIA College of Physical Education Jilin UniversityChangchun130012China China Japan Union Hospital Jilin UniversityChangchun130012China Health Nutrition Graduate School of Agricultural and Life SciencesThe University of Tokyo1130032Japan Faculty of Sport Sciences Waseda UniversityTokorozawa3591192Japan

Mental disorders such as depression and anxiety inflict significant burdens on individuals and *** prescribed treatments often involve cognitive therapy and ***,for patients resistant to these conventional methods,alternative therapies like the Ketogenic Diet(KD)offer a promising *** and its key metabolite,β-hydroxybutyrate(BHB),have been hypothesized to alleviate mental disorders through antiinflammatory actions,a crucial pathway in the pathophysiology of *** mini-review examines 15 clinical trials exploring the influence of KD and BHB on inflammation and their potential roles in managing mental *** human and animal studies were scrutinized to elucidate possible cellular and molecular *** of the 15 trials,10 reported reduced levels of at least one inflammatory mediator or mRNA post KD or BHB treatment,while two observed an elevation in anti-inflammatory *** findings suggest that KD and BHB could modulate cellular inflammatory pathways,highlighting their potential for therapeutic application in mental disorders.

关键词： Ketone body Ketogenic diet Depression Anxiety Neuroinflammation

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Pyrolysis Characteristics and Kinetics of Municipal Solid Waste

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Transactions of Tianjin University 2005年第5期11卷 353-359页

作者：李海英张书延赵新华 EIJI suzuki School of Environment Science and Technology Tianjin University Department of Fine Material Engineering Shinshu University

Based on a systemic survey, the pyrolysis characteristics and apparent kinetics of the municipal solid waste （ MSW） under different conditions were researched using a special pyrolysis reactor, which could overcome the disadvantage of thermo-gravimetric analyzer. The thermal decomposition behaviour of MSW was investigated using thermo-gravimetric （ TG ） analysis at rates of 4.8,6.6,8.4, 12.0 and 13. 2 K/min. The pyrolysis characteristics of MSW were also studied in different function districts. The pyrolysis of MSW is a complex reaction process and three main stages are found according to the results. The first stage represents the degradation of cellulose and hemicellulose, with the maximum degradation rate occuring at 150℃ -200 ℃： the second stage represents dehydrochlorination and depolymerization of intermediate products and the differential thermogravimetric （ DTG ） curves have shoulder peaks at about 300℃： the third stage is the decomposition of the residual big molecular organic substance and lignin at 400 ℃- 600 ℃. Within the range of given experimental conditions, the results of non-linear fitting algorithm and experiment are in agreement with each other and the correlation coefficients are over0. 99. The kinetic characteristics are concerned with the material component and heating rate. The activation energy of reaction decreases with the increase of heating rate.

关键词： mun cipal solid waste pyrolysis characteristics, kinetic, non-linear fitting algorithm

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Automated crystal structure analysis based on blackbox optimisation

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npj Computational Materials 2020年第1期6卷 1022-1028页

作者： Yoshihiko Ozaki Yuta suzuki Takafumi Hawai Kotaro Saito Masaki Onishi Kanta Ono Artificial Intelligence Research Center(AIRC) National Institute of Advanced Industrial Science and Technology(AIST)TokyoJapan GREE Inc.TokyoJapan Institute of Materials Structure Science(IMSS) High Energy Accelerator Research Organization(KEK)IbarakiJapan SOKENDAI(The Graduate University for Advanced Studies) IbarakiJapan Paul Scherrer Institute VilligenSwitzerland Medley IncTokyoJapan

In the present study,we show that time-consuming manual tuning of parameters in the Rietveld method,one of the most frequently used crystal structure analysis methods in materials science,can be automated by considering the entire trial-and-error process as a blackbox optimisation *** automation is successfully achieved using Bayesian optimisation,which outperforms both a human expert and an expert-system type automation despite the absence of *** approach stabilises the analysis quality by eliminating human-origin variance and bias,and can be applied to various analysis methods in other areas which also suffer from similar tiresome and unsystematic manual tuning of extrinsic parameters and human-origin variance and bias.

关键词： analysis black structure

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Fabrication,nanostructures and electronic properties of nanodiamond-based solar cells

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Progress in Natural Science:Materials International 2010年第1期20卷 38-43页

作者： Akihiko NAGATA Takeo OKU Kenji KIKUCHI Atsushi suzuki Yasuhiro YAMASAKI Eiji OSAWA Department of Materials Science The University of Shiga Prefecture Orient Chemical industries Co.Ltd. Department of New Business8-1 Sanra-Higashi-MachiNeyagawaOsaka572-8581Japan 3. NanoCarbon Research Institute Ltd.3-15-1 TokidaUedaNagano386-8567Japan

Nanodiamond-based solar cells were fabricated and the photovoltaic properties were ***(C60)and fullerenol(C60(OH)10-12)were used as n-type semiconductors,and diamond nanoparticles and metal phthalocyanine derivative were used as p-type *** nanostructures of the solar cells were investigated by transmission electron microscopy and X-ray diffracometry,and the electronic property was discussed.

关键词： solar cell nanodiamond C60 phthalocyanine

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Hypoxia and fatty liver

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World Journal of Gastroenterology 2014年第41期20卷 15087-15097页

作者： Tomohiro suzuki Satoko Shinjo Takatomo Arai Mai Kanai Nobuhito Goda Department of Life Science and Medical BioScience Waseda University School of Advanced Science and Engineering

The liver is a central organ that metabolizes excessive nutrients for storage in the form of glycogen and lipids and supplies energy-producing substrates to the peripheral tissues to maintain their function,even under starved *** processes require a considerable amount of oxygen,which causes a steep oxygen gradient throughout the hepatic *** consumption and/or excessive food intake can alter the hepatic metabolic balance drastically,which can precipitate fatty liver disease,a major cause of chronic liver diseases worldwide,ranging from simple steatosis,through steatohepatitis and hepatic fibrosis,to liver *** hepatic metabolism and tissue remodeling in fatty liver disease further disrupt hepatic oxygen homeostasis,resulting in severe liver *** master regulators of adaptive responses to hypoxic stress,hypoxia-inducible factors(HIFs) modulate various cellular and organ functions,including erythropoiesis,angiogenesis,metabolic demand,and cell survival,by activating their target genes during fetal development and also in many disease conditions such as cancer,heart failure,and *** the past decade,it has become clear that HIFs serve as key factors in the regulation of lipid metabolism and fatty liver *** review discusses the molecular mechanisms by which hypoxia and HIFs regulate lipid metabolism in the development and progression of fatty liver disease.

关键词： Hypoxia Fatty liver disease Hypoxia-inducible factor Lipid metabolism Obstructive sleep apnea

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Indirect photocatalytic reduction of arsenate to arsenite in aqueous solution with TiO_2 in the presence of hole scavengers

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Chinese Journal of Chemical Engineering 2018年第3期26卷 529-533页

作者： Abdus Samad Shamim Ahsan Ikki Tateishi Mai Furukawa Hideyuki Katsumata Tohru suzuki Satoshi Kaneco Department of Chemistry Jagannath University Department of Earth and Atmospheric Sciences Metropolitan State University of Denver Department of Chemistry for Materials Graduate School of Engineering Mie University Mie Global Environment Center for Education & Research Mie University

The indirect photocatalytic reduction of arsenate to arsenite in aqueous solution with titanium dioxide(TiO_2)was investigated with various hole scavengers such as methanol, ethanol, 2-propanol, formaldehyde, acetone,formic acid and acetic acid. Although the direct photocatalytic reduction of arsenate to arsenite with TiO_2 was impossible, an indirect reduction of As(V) was possible in the presence of sacrificial electron donors to form strongly reductive radicals. The addition of ethanol was very effective for indirect photocatalytic reduction of As(V) in aqueous solution with TiO_2 photocatalyst. The indirect photocatalytic reduction rate of As(V) may be related with both the reaction rate constants of reaction of hydroxyl radicals with hole scavenger and the reactivities for the radicals M· which are produced by the reaction of ·OH with hole scavenger.

关键词： Indirect photocatalytic reduction Arsenate Arsenite Titanium dioxide Hole scavenger

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Extraction of resonance parameters from meson production reaction

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Chinese Physics C 2009年第12期33卷 1140-1145页

作者： T. Sato N. suzuki T. -S. H. Lee Department of Physics Osaka University Toyonaka Osaka 560-0043 Japan Excited Baryon Analysis Center(EBAC) Thomas Jefferson National Accelerator Facility Newport News Virginia 23606 USA Physics Division Argonne National Laboratory Argonne IL 60439 USA

We have developed an analytic continuation method for extracting parameters of nucleon resonances within a Hamiltonian formulation of meson-nucleon reactions. The method was tested for simple solvable models and then applied for our recent coupled channels model （πN, ηN, π△, ρN, and σN ） of the π＊N and γ＊N reactions. The resonance pole positions and their properties are studied for P11and P11 channels.

关键词： baryon resonance meson production reaction resonance pole

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Metallic Contaminant Detection using a High-Temperature Superconducting Quantum Interference Devices Gradiometer

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Chinese Physics Letters 2010年第8期27卷 253-255页

作者： Saburo Tanaka Tomohiro Akai Makoto Takemoto Yoshimi Hatsukade Takeyoshi Ohtani Yoshio Ikeda Shuichi suzuki Toyohashi University of Technology 1-1 Hibarigaoka Tempaku-cho Toyohashi Aichi 441-8580 Japan Advance Food Technology Co. Ltd. Toyohashi Aichi 441-8113 Japan

We develop magnetic metallic contaminant detectors using high-temperature superconducting quantum interference devices （HTS-SQUIDs） for industrial products. Finding ultra-small metallic contaminants is an important issue for manufacturers producing commercial products such as lithium ion batteries. If such contaminants cause damages, the manufacturer of the product suffers a big financial loss due to having to recall the faulty products. Previously, we described a system for finding such ultra-smafi particles in food. In this study, we describe further developments of the system, for the reduction of the effect of the remnant field of the products, and we test the parallel magnetization of the products to generate the remnant field only at both ends of the products. In addition, we use an SQUID gradiometer in place of the magnetometer to reduce the edge effect by measuring the magnetic field gradient. We test the performances of the system and find that tiny iron particles as small as 50 × 50 μm^2 on the electrode of a lithium ion battery could be clearly detected. This detection level is difficult to achieve when using other methods.

关键词： HIGH temperature superconductors SUPERCONDUCTING quantum interference devices PHYSICAL measurements INDUSTRIAL goods LITHIUM-ion batteries MAGNETIZATION PERFORMANCE evaluation

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