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Asian Journal of Andrology 2015年第5期17卷 797-801,I0008-I0009页

作者： Nilgun Gurbuz Arif Kol Tumay Ipekci Erhan Ates asli Baykal Mustafa F Usta Department of Biochemistry Akdeniz University School of Medicine Antalya Turkey Department of Urology Section of Andrology Akdeniz University School of Medicine Antalya Turkey

The relationship between erectile dysfunction （ED） and chronic renal failure （CRF） has been reported in several studies. This study aimed to investigate whether the chronic use of sildenafil could enhance the erectile capacity in CRF-induced rats. In addition, we assessed the effect of that treatment on certain molecules, which have been suggested to play crucial roles in erectile physiology and CRF-related ED as well. Three groups of animals were utilized：（1） age-matched control rats, （2） CRF-induced rats, （3） CRF-induced rats treated with chronic administration of sildenafil （5 mg kg^-1 p.o. for 6 weeks [treatment started after 6 weeks of CRF induction]）. At 3 months, all animals underwent cavernosal nerve stimulation （CNS） to assess erectile function. Penile tissue advanced glycation end products （AGE＇s）/5-hydroxymethyl-2-furaldehyde, malondialdehyde （MDA）, cGMP （ELISA）, inducible nitric oxide synthase （iNOS） and neuronal NOS （nNOS）（Western blot） analyses were performed in all rat groups. CRF-induced rats had a significant decrease in erectile function when compared to control rats （P 〈 0.05）. The increase in both intracavernosal pressure （ICP） and area under the curve of CRF-induced rats treated with sildenafil （Group 3） was greater than CRF-induced rats （Group 2）. Additionally, sildenafil treatment decreased AGE, MDA and iNOS levels, while it preserved nNOS and cGMP contents in CRF-induced penile tissue. Decreased AGE, MDA, iNOS and increased nNOS, cGMP levels at the sildenafil-treated group increased both ICP and Total ICP to CNS, which led to improve erectile function in CRF-induced rats. The results of the present study revealed the therapeutic effect of chronic sildenafil administration on erectile function in CRF-induced rats.

关键词： chronic renal failure erectile function sildenafil

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The Effect of Storage Solutions on Mineral Content of Enamel

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Materials Sciences and Applications 2013年第7期4卷 439-445页

作者： asli Secilmis Erhan Dilber Nilgun Ozturk Fatma Gokmen Yilmaz Department of Prosthodontics Faculty of DentistryUniversity of GaziantepGaziantepTurkey Department of Prosthodontics Faculty of DentistrySifa UniversityİzmirTurkey Department of Prosthodontics Faculty of DentistryUniversity of SelcukKonyaTurkey Department of Soil Science Faculty of AgriculturalUniversity of SelcukKonyaTurkey

Purpose: This study evaluated the influence of different storage times and storage solutions on the mineral content of enamel. Methods: Ninety enamel slabs were randomly divided into 2 groups of 45: a 45-day group and a 90-day group. Each of these main groups was further subdivided into 9 experimental groups of 5 slabs, and each subgroup was stored in a different storage solution. The mean percentage weights of 5 elements (calcium, potassium, sodium, phosphorus, and magnesium) presented in each enamel slab was measured after storage using inductively coupled plasmaatomic emission spectrometry. Two-way analysis of variance (ANOVA) and Turkey’s honestly significant difference tests were used to analyze differences between the groups. Results: Storage conditions significantly affected the levels of calcium, potassium, sodium, and phosphorus (p 0.05). Storage procedures can significantly affect the calcium, potassium, sodium, and phosphorus contents of enamel.

关键词： Storage Solution Storage Time Enamel ICP-AES Mineral Content

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Effect of Surface Treatment on Elemental Composition of Recast NiCr Alloy

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Materials Sciences and Applications 2012年第3期3卷 163-167页

作者： Tevfik Yavuz asli Acar Serhan Akman Atiye Nilgun Ozturk Department of Prosthodontics Selcuk UniversityKonyaTurkey Department of Prosthodontics Gaziantep UniversityGaziantepTurkey

Objective: The aim of this study was to compare the effects of different surface treatments on the elemental composition stability of as-received and recast types of NiCr casting alloys. Material and Methods: Six commercial NiCr dental casting alloys (Kera N, Nodelco, Bellabond, Wiron 99, Metaplus VK, and Tritech D) were used in this study. Seventy-two specimens (12 × 12 × 1.2 mm) were produced using the lost-wax casting process. Three casting protocols were established in relation to the proportion of as-received and recast alloys: Group A (100% as-received metal), Group B (50 wt% new metal, 50 wt% once-recast metal), and Group C (100% once-recast metal). Two specimens in every group received two different surface treatments: sandblasting with 110 μmm Al2O3 or oxidation firing. An elemental analysis was performed with x-ray energy-dispersive spectroscopy. Results were subjected to one-way analysis of variance and Tukey HSD tests. Results: The elemental composition was significantly different in the casting groups and treatment groups (p < 0.05). The lowest mean weight percentage Ni value was recorded for Group C and the highest for Group A. Aluminum-oxide sandblasting of the alloy surface reduced the mean weight percentage for Cr. Conclusion: Recasting metal alloys may adversely affect surface quality.

关键词： Recasting Elemental Composition NiCr Alloy

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Magnetohydrodynamic Calculations of Toroidal Fusion Reactor to Ensure Stable Control

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Open Journal of Applied Sciences 2016年第7期6卷 402-408页

作者： Aybaba Hançerlioğullari asli Kurnaz Yosef G. Ali Madee Department of Physics Faculty of Arts and Sciences Kastamonu University Kastamonu Turkey

The development of magnetic configurations to confine the stability fluid plasmas for fusion energy is a challenge that is a mixture of basic fusion engineering and invention. In order to keep the fusion reactions in the plasma to be continuing in the fusion reactors, the speed of tritium breeding (TBR) should be kept above a certain value. At the Apex fusion reactor, a fast flowing thin liquid wall has replaced the solid first wall concept of the traditional reactors. Behind the fast flowing thin liquid wall, a slower and thicker second liquid wall (coat) is present. Monte Carlo Random method (MCRS) is the general name for the solution of experimental and statistical problems with a random approach. This method is dependent upon the theory of probability. In the present work, Mhd impacts are investigated quite unimportant for Flibe salt solutions. In this study, the fissile fuel production calculations are done for a neutron wall load of 10 MW/m2 fissile fuel production rates of 238U(n, γ)239Pu and 232Th(n,γ)233U increases almost linearly with increased heavy metal content.

关键词： Fusion Reactor Monte Carlo Magnetohydrodynamic Tritium Breeding (TBR)

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A case of sarcoidosis associated with chronic eosinophilic pneumonia

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Case Reports in Clinical Medicine 2014年第2期3卷 89-91页

作者： Halil Yanardag Cuneyt Tetikkurt asli Sezgin Ertugrul Oruc Muammer Bilir Department of Internal Medicine Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey Department of Pulmonary Diseases Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey Department of Pathology Cerrahpasa Medical FacultyIstanbul UniversityIstanbulTurkey

A 78-year-old woman was referred to our university hospital due to dry cough, fever, and weight loss. Laboratory revealed blood eosinophilia, high ESR, CRP and LDH. Rheumatologic markers were negative. Chest X-ray showed ground glass opacities in upper lobes. Uveitis developed in the left eye 1 week after admission. Thorax CT revealed ground glass opacities, reticular appearence in the upper lobes, enlarged axillary and mediastinal lymph nodes. Bronchoalveolar lavage CD4/CD8 was 2.1 and had 48% eosinophils. Histopathologic examination revealed eosinophilic infiltration and non-caseating epitheloid granulomas in the lung and mediastinal lymph nodes without vasculitis. Symptoms, blood eosinophilia and initial thorax CT findings improved after two months of methylprednisolone treatment. Chronic eosinophilic pneumonia is a rare disease characterized by systemic and pulmonary manifestations. It may be associated with other diseases.

关键词： Sarcoidosis Chronic Eosinophilic Pneumonia Pulmonary Eosinophilia

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Coffee:The magical bean for liver diseases

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World Journal of Hepatology 2017年第15期9卷 689-696页

作者： Ryan D Heath Mihir Brahmbhatt asli C Tahan Jamal A Ibdah Veysel Tahan Division of Gastroenterology and Hepatology University of MissouriColumbiaMU 65201United States

Coffee has long been recognized as having hepatoprotective properties,however,the extent of any beneficial effect is still being *** appears to reducerisk of hepatocellular carcinoma,reduce advancement of fibrotic disease in a variety of chronic liver diseases,and perhaps reduce ability of hepatitis C virus to *** review aims to catalog the evidence for coffee as universally beneficial across a spectrum of chronic liver diseases,as well as spotlight opportunities for future investigation into coffee and liver disease.

关键词：咖啡 Hepatocellular 癌肝肝炎脂肪肝

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A Life-Threatening Condition in A Child With Chicken Pox: Eczema Herpeticum

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Open Journal of Pediatrics 2011年第1期1卷 1-3页

作者： Coskun CELTIK Yasemin KARAL asli KIBRIS Deniz KIRCUVAL Binnur TUZUN Trakya University Faculty of Medicine Department of Pediatrics Trakya University Faculty of Medicine Department of Dermatology

Eczema herpeticum is a severe infectious eruption caused by Herpes group viruses. The disease usually occurs in the patients with pre existing dermatosis, expecially atopic dermatitis. A three-year-old boy who has high fever and widespread skin eruptions with vesiculopustuler eruptions, erosions and ulcers was brought out to our emergency clinic. The patient had no pre-existing dermatosis, but he had suffered from chicken-pox. As serological, the antibodies of Varicella-IgM and Herpes simplex-IgM were positive. Eczema Herpeticum which occurred on a chicken-pox was diagnosed according to his history, physical examination, laboratory and pathologic findings. Acyclovir and empiric antibiotherapy together with the symptomatic therapy were used for treatment. His skin lesions recovered in one week after these therapies. The aim of this case-report is to emphasize the features of eczema herpeticum which occurred on a pre-existing varicella eruption.

关键词： Eczema herpeticum Kaposi’s varicelliform eruption varicella chicken pox herpes virus dermatitis child.

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家长与教师对校园护士角色期望的量表研制

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International Journal of Nursing Sciences 2017年第3期4卷 303-310页

作者： Ayla Bayik Temel Julide Gulizar Yildirim asli Kalkim Leyla Muslu Nilufer Yildirim Izmir Katip(C)elebi University Faculty of Health SciencesPublic Health Nursing Department(I)zmirTurkey Ege University Faculty of Nursing Public Health Nursing Department35100BornovaIzmirTurkey Akdeniz University Antalya School of HealthAntalyaTurkey Izmir Turkey

目的开发一个有效、可靠的评估工具,用以评判家长和教师对校园护士角色的期望。方法设计家长和教师对校园护士角色期望量表,应用于土耳其中小学。采用条目变异评估、内部一致性评价、因子分析、各量表总分与各维度的相关系数、量表重测... 详细信息

目的开发一个有效、可靠的评估工具,用以评判家长和教师对校园护士角色的期望。方法设计家长和教师对校园护士角色期望量表,应用于土耳其中小学。采用条目变异评估、内部一致性评价、因子分析、各量表总分与各维度的相关系数、量表重测信度进行数据分析。结果量表的内容效度指数为0.94。主成分分析方差最大化旋转结果,从54个项目获得了7个因子。其Cronbach's a系数为0.82~0.92。重测信度的组内相关系数为0.859。结论该量表是一个有效和可靠的评估工具,可用于评判家长和教师对校园护士角色的期望。

关键词：护士作用中小学校护理量表信度效度

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Current state and clinical outcome in Turkish patients with hepatocellular carcinoma

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World Journal of Hepatology 2018年第1期10卷 51-61页

作者： Omer Ekinci Bulent Baran asli Cifcibasi Ormeci Ozlem Mutluay Soyer Suut Gokturk Sami Evirgen Arzu Poyanli Mine Gulluoglu Filiz Akyuz Cetin Karaca Kadir Demir Fatih Besisik Sabahattin Kaymakoglu Department of Gastroenterohepatology Istanbul Faculty of Medicine Istanbul University Department of Internal Medicine Istanbul Faculty of Medicine Istanbul University Department of Gastroenterology Ko? University Hospital Department of Radiology Istanbul Faculty of Medicine Istanbul University Department of Pathology Istanbul Faculty of Medicine Istanbul University

AIM To investigate clinical, etiological, and prognostic features in patients with hepatocellular *** Patients with hepatocellular carcinoma who were followed-up from 2001 to 2011 were included in the study. The diagnosis was established by histopathological and/or radiological criteria. We retrospectively reviewed clinical and laboratory data, etiology of primary liver disease, imaging characteristics and treatments. ChildPugh and Barcelona Clinic Liver Cancer stage was determined at initial diagnosis. Kaplan-Meier survival analysis was done to find out treatment effect on survival. Risk factors for vascular invasion and overall survival were investigated by multivariate Cox regression analyses. RESULTS Five hundred and forty-five patients with hepatocellular carcinoma were included in the study. Viral hepatitis was prevalent and 68 patients either had normal liver or were non-cirrhotic. Overall median survival was 16(13-19) mo. Presence of extrahepatic metastasis was associated with larger tumor size(OR = 3.19, 95%CI: 1.14-10.6). Independent predictor variables of vascular invasion were AFP(OR = 2.95, 95%CI: 1.38-6.31), total tumor diameter(OR = 3.14, 95%CI: 1.01-9.77), and hepatitis B infection( OR = 5.37, 95 % CI : 1.23-23.39). Liver functional reserve, tumor size/extension, AFP level and primary treatment modality were independent predictors of overall survival. Transarterial chemoembolization(HR = 0.38, 95%CI: 0.28-0.51) and radioembolization(HR = 0.36, 95%CI: 0.18-0.74) provided a comparable survival benefit in the real life setting. Surgical treatments as resection and transplantation were found to be associated with the best survival compared with loco-regional treatments(log-rank, P < 0.001).CONCLUSION Baseline liver function, oncologic features including AFP level and primary treatment modality determines overall survival in patients with hepatocellular carcinoma.

关键词： Hepatocellular carcinoma Cirrhosis Alfafetoprotein Prognosis Treatment Survival

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Propolis reduces bacterial translocation and intestinal villus atrophy in experimental obstructive jaundice

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World Journal of Gastroenterology 2007年第39期13卷 5226-5231页

作者： Mehmet Zafer Sabuncuoglu Kemal Kismet Sibel Serin Kilicoglu Bulent Kilicoglu Serap Erel Sabahattin Muratoglu asli Elif Sunay Esra Erdemli Mehmet Ali Akkus 4th General Surgery Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Department of Histology and EmbriologyUfuk University School of Medicine Ankara 06520 Turkey Microbiology Department Ankara Training and Research Hospital Ulucanlar Ankara 06340 Turkey Food Engineer Balparmak Pazarlama Cekmekoy 34760 Istanbul Turkey Department of Histology and Embriology Ankara University School of Medicine 06100 Ankara Turkey

AIM: To investigate the effects of propolis on bacterial translocation and ultrastructure of intestinal morphology in experimental obstructive jaundice. METHODS: Thirty Wistar-Albino male rats were randomly divided into three groups, each including 10 animals: group—effect on ileal mucosa and reduced bacterial translocation in the experimental obstructive jaundice model. Further studies should be carried out to explain the mechanisms of these effects.

关键词：梗阻性黄疸细菌传播肠阻塞肠绒毛

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