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Redefining hemorrhoid therapy with endoscopic polidocanol foam sclerobanding

World Journal of Gastroenterology 2024年第36期30卷 4021-4024页

作者： asad gul rao Abdulqadir J Nashwan Department of Clinical Medicine Dow Medical CollegeKarachi 74200Pakistan Department of Nursing&Midwifery Research Hamad Medical CorporationDoha 3050Qatar

Hemorrhoids are a common and painful condition,with conventional treatments such as endoscopic rubber band ligation(ERBL)and injection sclerotherapy often falling short due to high recurrence rates and significant post-operative pain.A clinical trial by Qu et al introduces a novel approach called endoscopic polidocanol foam sclerobanding(EFSB).This multicenter randomized trial involved 195 patients with grade II and III internal hemorrhoids and demonstrated that EFSB significantly reduced recurrence rates and post-procedural pain while improving symptom relief and patient satisfaction compared to *** study's strengths include its robust design,comprehensive outcome evaluation,and patient-centered *** limitations such as the single-blind design and relatively short follow-up period,the findings suggest that EFSB could enhance clinical practice by offering a more effective and patient-friendly treatment *** research is needed to validate these results and explore the long-term benefits and cost-effectiveness of EFSB.

关键词： Hemorrhoids Endoscopic polidocanol foam sclerobanding Rubber band ligation Injection sclerotherapy Hemorrhoids recurrence Post-operative pain

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A Game-Theoretic Approach to Safe Crowd Evacuation in Emergencies

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Computers, Materials & Continua 2024年第4期79卷 1631-1657页

作者： Maria gul Imran Ali Khan Gohar Zaman Atta Rahman Jamaluddin Mir Sardar asad Ali Biabani May IssaAldossary Mustafa Youldash Ashraf Saadeldeen Maqsood Mahmud Asiya Abdus Salam Dania Alkhulaifi Abdullah AlTurkey31Department of Computer Science COMSATS University IslamabadAbbottabad CampusAbbottabad22010Pakistan Department of Computer Science Abbottabad University of Science and TechnologyAbbottabad22010Pakistan Department of Computer Science College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Science and Technology Unit Umm Al-Qura UniversityMakkah21955Saudi Arabia Deanship of Scientific Research Umm Al-Qura UniversityMakkah21955Saudi Arabia Department of Computer Information Systems College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Department of Computer Engineering College of Computer Science and Information TechnologyImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Department of Computer Science Faculty of Computer Science and Information TechnologyOmdurman Islamic UniversityOmdurman14415Sudan Business Analytic Program Department of Management and MarketingCollege of Business AdministrationUniversity of BahrainSakhir32038Bahrain

Obstacle removal in crowd evacuation is critical to safety and the evacuation system efficiency. Recently, manyresearchers proposed game theoreticmodels to avoid and remove obstacles for crowd evacuation. Game theoreticalmodels aim to study and analyze the strategic behaviors of individuals within a crowd and their interactionsduring the evacuation. Game theoretical models have some limitations in the context of crowd evacuation. Thesemodels consider a group of individuals as homogeneous objects with the same goals, involve complex mathematicalformulation, and cannot model real-world scenarios such as panic, environmental information, crowds that movedynamically, etc. The proposed work presents a game theoretic model integrating an agent-based model to removethe obstacles from exits. The proposed model considered the parameters named: (1) obstacle size, length, andwidth, (2) removal time, (3) evacuation time, (4) crowd density, (5) obstacle identification, and (6) route *** proposed work conducts various experiments considering different conditions, such as obstacle types, obstacleremoval, and several obstacles. Evaluation results show the proposed model’s effectiveness compared with existingliterature in reducing the overall evacuation time, cell selection, and obstacle removal. The study is potentially usefulfor public safety situations such as emergency evacuations during disasters and calamities.

关键词： Safe crowd evacuation public safety emergency transition probability cooperation

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Tree ring derived summer temperature variability over the past millennium in the western Himalayas of northern Pakistan

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Frontiers of Earth Science 2023年第4期17卷 1026-1036页

作者： Fayaz asad Haifeng ZHU Tabassum YASEEN Ru HUANG Mukund Palat rao Department of Botany Bacha Khan University CharsaddaKhyber Dakhtun Khaw 24420Pakistan State Key Laboratory of Tibetan Plateau Earth System Resources and Environment(TPESRE)Institute of Tibetan Plateau ResearchChinese Academy of SciencesBeijing 100101China China Pakistan Joint Research Center on Earth Sciences CAS-HECIslamabad 45320Pakistan Centre de Recerca Ecològica i Aplicacions Forestals Barcelona 08193Spain Department of Plant Science University of California Davis(UC Davis)95616CaliforniaUSA Tree Ring Laboratory Lamont-Doherty Earth ObservatoryColumbia UniversityNY 10964USA

Long-term high resolution climate proxies are essential for understanding climate variability particularly,in regions such as the western Himalayas of northern Pakistan,where few long-term climate records are *** standard dendrochronological methods,an 1132-year(882 to 2013 C.E.)tree-ring chronology of Juniperus excelsa *** was established from the western Himalayas,northern Pakistan(WHNP).Tree growth was negatively and significantly(r=-0.65)correlated with the growing season(June-July)mean temperature,and positively and weakly(r=0.22)associated with *** inverse relationship of tree radial growth with temperature and positive association with precipitation demonstrated that forest growth is sensitive to high temperature related *** a reliable STD chronology and robust reconstruction model,a 928-year(1086 to 2013 C.E.)mean temperature reconstruction was developed for the WHNP using the substantial negative correlation between the summer temperature and standard tree ring-width *** to statistical validation,the reconstruction accounted for 41.6% of the climatic variation for the period of 1956-2013 *** *** extreme-warm periods occurred in 1093 C.E.(29.42℃)and extreme cold periods in 1088 C.E.(26.99℃)observed during the past 928 *** reconstruction's multi-taper method(MTM)spectral analysis reveals significant(p<0.05)2-3-year and 63.8-year *** the 2-3-year cycle occurred within the range of ENSO variation,which indicates that ENSO had an impact on the regional temperature in our studied area.

关键词： tree rings Juniperus excelsa dendrochronology reconstruction western Himalaya

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Physicochemical,rheological and antioxidant profiling of yogurt prepared from non-enzymatically and enzymatically hydrolyzed potato powder under refrigeration

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Food Science and Human Wellness 2023年第1期12卷 69-78页

作者： Ishtiaq Ahmad Zhouyi Xiong Hanguo Xiong Rana Muhammad Aadil Nauman Khalid Allah Bakash Jvaid Lakhoo Zia-ud-din asad Nawaz Noman Walayat rao Sanaullah Khan College of Food Science and Technology Huazhong Agricultural UniversityWuhan 430070China Fisheries Research Institute Wuhan Academy of Agricultural SciencesWuhan 430207China National Institute of Food Science and Technology University of AgricultureFaisalabad 38000Pakistan Schools of Food and Agricultural Sciences University of Management and TechnologyLahore 54000Pakistan College of Food Science and Technology Zhejiang University of TechnologyHangzhou 310014China

Evidences show that the storage period greatly affects the quality of *** this study,three types of yogurt:control yogurt(CY),non-hydrolyzed potato powder yogurt(PPY)and enzymatically hydrolyzed potato powder yogurt(EHPPY)were prepared at 42℃ for 5 h and stored for 28 days at 4℃.The yogurts were evaluated for quality characteristics at different storage *** differences in pH values,titratable acidities and viable counts were detected in all three types of yogurt during ***,compared to other yogurts,EHPPY exhibited desirable water holding capacity,throughout the storage *** from this,sensory properties and antioxidant activities(2-diphenyl-1-picryl-hydrazyl(DPPH)free radical scavenging activity and ferric reducing antioxidant power(FRAP))of EHPPY were also significantly improved during the storage ***,the storage(G’)and loss(G”)modulus of PPY,EHPPY were lower than CY at 4℃ while a hysteresis loop was shown by all yogurts at the temperature range of 4-50℃ indicating higher G’(elasticity)than G”(viscosity).Based on our findings,EHPP could be an important functional ingredient in improving the quality and storage stability of yogurt for its production at an industrial level.

关键词： Storage stability Potato powder Yogurt Rheology Microbiology Antioxidant activity

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Potential Antioxidant Activities Improve Salt Tolerance in Ten Varieties of Wheat (<i>Triticum aestivum</i>L.)

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American Journal of Plant Sciences 2013年第6期4卷 69-76页

作者： Aurangzeb rao Syed Dilnawaz Ahmad Syed Mubashar Sabir Shahid Iqbal Awan asad Hussain Shah Syed Rizwan Abbas Saima Shafique Fareed Khan Atia Chaudhary Department of Chemistry University of the Poonch Rawalakot Pakistan. Department of Plant Breeding and Molecular Genetics Faculty of Agriculture University of the Poonch Rawalakot Pakistan Department of Plant Breeding and Molecular Genetics Faculty of Agriculture University of the Poonch Rawalakot Pakistan University of Azad Jammu and Kashmir Muzaffarabad Pakistan

The activity of antioxidative enzymes system is affected by salt stress, chlorophyll content (CHL), leaf relative water content (RWC), Na+ and K+ contents, their ratio and some oxidative stress indices were studied in leaves of ten bread wheat cultivarsSehar-06, Lu-26, NARC-09, BARC-09 and Pirsbak-09’(salt-tolerant) and Kaghan-94, Rohtas-90, Soughat-90, Shaheen-94 and Zardana-89’(salt-sensitive), grown under salinity treatments carried out in five levels (1 dS·m-1 as control, 2, 4, 8, 16 dS·m-1) via sodium chloride. Under high salt potency significant increase for activities of antioxidant enzymes such as ascorbate peroxidase (APX) and guiacol peroxidase (GPX), occured in salt tolerant varieties. Meanwhile, under salinity condition the activities of antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) and (GPX) in sensitive cultivar were lower than control. Regarding (APX) activity there was no significant difference between salinity and control situation. Under salt stress membrane stability index (MSI) of both cultivars were negatively influenced. Hydrogen peroxide (H2O2) content of salinity sensitive cultivars was higher than control. Salt tolerant varieties had more amounts of K+ content, K+ and Na+ ratio, relative water content, yield and chlorophyll under salt conditions, and sensitive ones recorded higher Na+ content at tillering stage. The mechanism of salt stress might be achieved due to low lipid peroxidation, assumingly lower changes in membrane stability index and evasion of Na+ combination and amplified activity of antioxidant enzymes.

关键词： Antioxidant Enzymes Chlorophyll Content+/Na+ Ratio Relative Water Content Salinity Wheat

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