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World journal of Gastroenterology 2021年第26期27卷 4194-4207页

作者： Irving Levine arvind j trindade Division of Gastroenterology Long Island Jewish Medical CenterZucker School of Medicine at Hofstra/NorthwellNorthwell Health SystemNew Hyde ParkNY 11040United States

Endoscopic ultrasound tissue acquisition,in the form of both fine needle aspiration(EUS-FNA)and fine needle biopsy(EUS-FNB),is utilized for pancreatic mass lesions,subepithelial lesions,and lymph node *** procedures are safe and yield high diagnostic *** its high diagnostic yield,EUS-FNA has potential limitations associated with cytological aspirations,including inability to determine histologic architecture,and a small quantitative sample for further immunohistochemical ***-FNB,with its larger core biopsy needle,was designed to overcome these potential ***,it remains unclear which technique should be used and for which *** trials are plagued by heterogeneity at every stage of comparison;including variable needles used,and different definitions of endpoints,which therefore limit ***,we present a review of prospective trials,systematic reviews,and meta-analyses on studies examining EUS-FNA vs *** comparative trials of EUS-FNA vs EUS-FNB primarily focus on pancreatic mass lesions,and yield conflicting results in terms of demonstrating the superiority of one ***,consistent among trials is the potential for diagnosis with fewer passes,and a larger quantity of sample achieved for next generation *** regard to subepithelial lesions and lymph node biopsy,fewer prospective trials exist,and larger prospective studies are *** on the available literature,we would recommend EUS-FNB for peri-hepatic lymph nodes.

关键词： Endoscopic ultrasound fine needle aspiration Endoscopic ultrasound fine needle biopsy Pancreatic lesions Subepithelial lesions Lymph node biopsy

Advanced imaging in surveillance of Barrett’s esophagus: Is the juice worth the squeeze?

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World journal of Gastroenterology 2019年第25期25卷 3108-3115页

作者： Sara A Cerrone arvind j trindade Division of Gastroenterology Long Island Jewish Medical CenterZucker School of Medicine at Hofstra/NorthwellNorthwell Health System

Esophageal cancer is on the *** known precursor lesion is Barrett’s esophagus(BE).Patients with dysplasia are at higher risk of developing esophageal *** the gold standard for surveillance endoscopy involves taking targeted biopsies of abnormal areas as well as random biopsies every 1-2 cm of the length of the Barrett’*** studies have shown that this surveillance can miss dysplasia and *** imaging technologies have been developed that may help detect dysplasia in *** opinion review discusses advanced imaging in BE surveillance endoscopy and its utility in clinical practice.

关键词： Barrett’s esophagus Advanced imaging Chromoendoscopy Endomicroscopy

Management of Barrett’s esophagus with dysplasia refractory to radiofrequency ablation

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World journal of Gastroenterology 2020年第17期26卷 2030-2039页

作者： Kara L Raphael arvind j trindade Division of Gastroenterology Long Island Jewish Medical CenterZucker School of Medicine at Hofstra/NorthwellNorthwell Health SystemNew Hyde ParkNY 11040United States

Radiofrequency ablation(RFA)is very effective for eradication of flat Barrett’s mucosa in dysplastic Barrett’s esophagus after endoscopic resection of raised ***,in a minority of the time,RFA may be ineffective at eradication of the Barrett’s *** complete eradication of intestinal metaplasia can be challenging in these *** review article focuses on the management of patients with dysplastic Barrett’s esophagus refractory to RFA *** strategies discussed in this review include optimizing the RFA procedure,optimizing acid suppression(with medical,endoscopic,and surgical management),cryotherapy,hybrid argon plasma coagulation,and EndoRotor resection.

关键词： Low-grade dysplasia High-grade dysplasia Radiofrequency ablation Cryotherapy EndoRotor Hybrid argon plasma coagulation Argon plasma coagulation

Emergency department utilization for gastrointestinal care and patient characteristics associated with hospital admission in a national cohort

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Gastroenterology Report 2023年第1期11卷 566-568页

作者： Kelly Suchman Nina Kohn arvind j.trindade Division of Gastroenterology Zucker School of Medicine at Hofstra/NorthwellLong Island Jewish Medical CenterNew Hyde ParkNYUSA Institute of Health Innovations and Outcomes Research Feinstein Institutes for Medical ResearchNorthwell HealthManhassetNYUSA

Introduction Gastrointestinal diseases and care in the USA account for a significant amount of healthcare resources and spending,recently totaling>$119 billion dollars annually[1].In addition to ambulatory sites and clinics,a substantial portion of gastrointestinal care occurs through the emergency department(ED).Though the overall rate of ED visits in the USA has remained stable over the past 10 years[2],the number of visits for gastrointestinal complaints has been increasing[1,3],contributing to rising healthcare costs.

关键词： gastrointestinal diseases ambulatory

Clinical controversies in endoscopic ultrasound

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Gastroenterology Report 2013年第1期1卷 33-41页

作者： arvind j.trindade Tyler M.Berzin Center for Advanced Endoscopy Division of GastroenterologyBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMA.USA

The field of diagnostic and therapeutic endoscopic ultrasound(EUS)is growing *** EUS has enhanced our ability to diagnose and treat a wide variety of GI conditions,there are many controversial issues regarding the appropriate application of EUS *** this review we discuss five controversial topics in EUS:the utility of EUS in staging of esophageal and gastric cancer;selection of appropriate needle gauge for fine needle aspiration(FNA);use of the stylet in FNA;and the emerging role of contrast agents in endoscopic ultrasound.

关键词： Endoscopic ultrasound controversies gastric cancer esophageal cancer contrast enhanced fine needle aspiration

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A drop of immunity

Molecular Plant 2021年第9期14卷 1437-1438页

作者： Ines trindade Institute for Biochemistry and Biology University of Potsdam14476 PotsdamGermany

Editor's Highlight Molecular Plant snRNA-seq to bulk RNA-seq from whole roots and protoplast suspensions,and captured additional cell subtypes using snRNA-seq that were missed in other published single-cell RNA-seq(scRNA-seq)*** de novo clustering of nuclei based on chromatin accessibility and integration of snATAC-seq with snRNA-seq produced similar clusters,suggesting that the complex Arabidopsis root cellular identities can be revealed by single-nuclei chromatin accessibility profiles(Farmer et al.t 2021).

关键词： immunity roots Arabidopsis

License to flower:LEAFY has pioneer activity

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Molecular Plant 2021年第5期14卷 719-720页

作者： Inês trindade Institute for Biochemistry and Biology University of PotsdamD-14476 PotsdamGermany

The transition to reproductive development is a key step in the lifecycle of a plant and requires fine-tuning of gene expression through the concerted action of several transcription factors(TFs).While most TFs bind naked DNA(without nucleosomes)in a sequence-specific manner,in mammals a special group with key roles in cell fate reprogramming,named pioneer TFs,can bind nucleosome-occupied *** Arabidopsis,LEAFY(LFY)promotes floral fate through activation of floral homeotic genes(Parcy et al.,1998),some of which are targeted by the Polycomb Repressive Complex 2 and localize to closed chromatin ***,LFY has been proposed to act as a pioneer TF,but whether/how it can bind occluded DNA remained unknown.

关键词： nucleosome LEAFY programming

Fuzzy Logic Based Handover Authentication in 5g Telecommunication Heterogeneous Networks

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Computer Systems Science & Engineering 2023年第7期46卷 1141-1152页

作者： j.Divakaran arvind Chakrapani K.Srihari Vivekanandha College of Engineering for Women TiruchengodeNamakkal637205TamilnaduIndia Karpagam College of Engineering Coimbatore641032TamilnaduIndia SNS College of Technology Coimbatore641035TamilnaduIndia

Under various deployment circumstances,fifth-generation(5G)telecommunications delivers improved network compound management with fast communication *** to the introduction of the Internet of Things(IoT)in data management,the majority of the ultra-dense network models in 5G networks frequently have decreased spectral efficiency,weak handover management,and *** majority of traditional handover authentication models are seriously threatened,making them vulnerable to a variety of security *** authentication of networked devices is the most important ***,a model that incorporates the handover mechanism and authentication model must be *** article uses a fuzzy logic model to create a handover and key management system that focuses on cloud handover management and authentication *** order to decrease delays in 5G networks,the fuzzy logic is built with multiple criteria that aim to reduce the number of executed handovers and target cell *** simulation is run to evaluate the model’s performance in terms of latency,spatial complexity,and other metrics related to authentication attack validation.

关键词： Handover authentication mobility management fuzzy logic latency 5G IoT MATLAB 3gpp

Behavior of ring footing resting on reinforced sand subjected to eccentric-inclined loading

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journal of Rock Mechanics and Geotechnical Engineering 2018年第2期10卷 347-357页

作者： Vaibhav Sharma arvind Kumar Dr.B.R.Ambedkar National Institute of Technology Jalandhar144011India

Ring footings are suitable for the structures like tall transmission towers, chimneys, silos and oil *** types of structures are susceptible to horizontal loads(wind load) in addition to their dead *** the literature, very little or no effort has been made to study the effect of ring footing resting on reinforced sand when subjected to eccentric, inclined and/or eccentric-inclined loadings. This paper aims to study the behavior of ring footing resting on loose sand and/or compacted randomly distributed fiberreinforced sand(RDFS) when subjected to eccentric(0 B, 0.05 B and 0.1 B, where B is the outer diameter of ring footing), inclined(0°,5°,10°, 15°,-5°,-10° and-15°)and eccentric-inclined loadings by using a finite element(FE) software PLAXIS 3 D. The behavior of ring footing is studied by using a dimensionless factor called reduction factor(RF). The numerical model used in the PLAXIS 3 D has been validated by conducting model plate load tests. Moreover, an empirical expression using regression analysis has been presented which will be helpful in plotting a load-settlement curve for the ring footing.

关键词： Soil reinforcement Ring footing Numerical method Randomly distributed fibers Load inclination Load eccentricity Model tests Reduction factor(RF)

Geo-environmental application of municipal solid waste incinerator ash stabilized with cement

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journal of Rock Mechanics and Geotechnical Engineering 2017年第2期9卷 370-375页

作者： Davinder Singh arvind Kumar Department of Civil Engineering Dr. B.R. Ambedkar National Institute of TechnologyJalandharPunjabIndia

The behavior of soluble salts contained in the municipal solid waste incinerator(MSWI) ash significantly affects the strength development and hardening reaction when stabilized with *** present study focuses on the compaction and strength behavior of mixed specimens of cement and MSWI ash.A series of indices such as unconfined compressive strength,split tensile strength,California bearing ratio(CBR) and pH value was *** to this,the specimens were cured for 7 d,14 d,and 28 *** test results depict that the maximum dry density(MDD) decreases and the optimum moisture content(OMC)increases with the addition of *** test results also reveal that the cement increases the strength of the mixed ***,the combination of MSWI ash and cement can be used as a lightweight filling material in different structures like embankment and road construction.

关键词： Municipal solid waste incinerator(MSWI) ash Cement Compaction Stabilization California bearing ratio(CBR) test Geotechnical properties