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Adjunctive effects of acupressure therapy on pain and quality of life in patients with knee osteoarthritis:an interventional study

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Journal of Acupuncture and Tuina Science 2021年第4期19卷 300-306页

作者： Meenu Rani Lokendra sharma Uma Advani arun sharma Department of Pharmacology Sawai Man Singh Medical College and HospitalJaipurRajasthan 302004India Department of Orthopedics Sawai Man Singh Medical College and HospitalJaipurRajasthan 302004India

Objective To investigate the effect of acupressure therapy as an adjunctive therapy to pharmacological treatment on pain and health-related quality of life(QOL)among knee osteoarthritis(KOA)*** One hundred KOA patients were recruited from the orthopedic out-patient clinic of the *** patients were allocated randomly(flipping-coin simple randomization method)into an intervention group(n=50)and a control group(n=50).Patients in the intervention group received acupressure therapy along with pharmacological *** in the control group did not receive acupressure therapy but continued their pharmacological *** in pain(visual analog scale,VAS)and QOL(short-form 36-item health survey,SF-36)scores at baseline(A0),during training session(A1),follow-up at the 3rd month after training(A2)and follow-up at the 6th month after training session(A3)were collected and *** regression analysis was used to check the relationship between pain and SF-36 *** The VAS score of participants in the intervention group decreased at A3(P=0.001).Scores of physical functioning(PF),role limitations due to emotional problems(RE)and mental health(MH)of SF-36 in the intervention group improved more as compared with the control *** in the intervention group with improvement in VAS(pain)score showed greater changes in mean scores of all domains of SF-36 from baseline(all P<0.05).Except bodily pain(BP),the other domains of SF-36 were negatively correlated with pain *** Acupressure therapy with pharmacological treatment can improve health-related QOL and pain among KOA patients.

关键词： Acupoint Therapy Osteoarthritis,Knee Quality of Life Short-form Health Survey Visual Analog Scale

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Fuzzy AHP approach for legal judgement summarization

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Journal of Management Analytics 2019年第3期6卷 323-340页

作者： Neha Bansal arun sharma R.K.Singh Department of Information Technology Indira Gandhi Delhi Technical University for WomenDelhiIndia

Legal documents are generally big and complex documents because of specific vocabulary,semantics and *** of the major challenges in legal processing systems is to generate summary of legal *** date,in most of the legal systems,the summary of judgements is produced manually by legal experts which are then used by Lawyers,Judges and other legal *** manual process of summarization is very inefficient and *** text summarization(ATS)is the process of reducing the content of a textual document,while retaining the core description of text through the use of appropriate *** present work proposes a novel Fuzzy Analytical Hierarchical process(FAHP)based feature weighting scheme which helps in producing an efficient and effective summary of legal *** is applied on a number of legal judgements taken from Indian IT *** of the model is done using ROUGE(Recall-Oriented Understudy for Gisting Evaluation)tool with recall,precision,and f-measure as performance *** generated summaries are further assessed by legal experts and are found to be more promising than the summaries generated by traditional approaches.

关键词： summarization fuzzy AHP feature extraction feature weighting legal information system legal knowledge management social science

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Fragment emission and critical behavior in light and heavy charged systems

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Chinese Physics C 2021年第1期45卷 215-225页

作者： Samiksha Sood Rohit Kumar arun sharma Sakshi Gautam Rajeev K.Puri Department of Physics Panjab UniversityChandigarh 160014India Department of Physics G.D.College.BillawarJammu 185204India

We study the emission of fragments in central collisions of light and heavily charged systems of^4+Ar+^45 Sc and^s4Kr+^197 Au,respectively,using the Quantum Molecular Dynamics(QMD)model as the primary *** fragments are identified using an energy based clusterization algorithm,i.e.,the Simulated Annealing Clusterization Algorithm(SACA).The charge distributions of intermediate mass fragments[3≤Zf≤12]are fitted with power-law(∝Zf^-τ)and exp on ential(∝e^-λZf)fits in order to extract the parametersτandλ,whose minimum values are also sometimes linked with the onset of fragmentation or the critical point for a liquid-gas phase *** parameters such as the normalized second moment,,average size of the second largest cluster,phase separation parameter(Sp),bimodal parameter(P),information entropy(H),and Zipfs law are also analyzed to find the exact energy of the onset of *** detailed analysis predicts that an energy point exists between 20-23.1 MeV/nucleon,which is very close to the experimentally observed value of 23.9 MeV/nucleon for the^40Ar+^45Sc *** also find that the critical energy deduced using Zipfs law is higher than those predicted from other critical ***,no minimum is found for t values of the highly charged system of^84Kr+^197Au,in agreement with experimental findings and various theoretical *** observe that the QMD+SACA model calculations are in agreement with the experimental *** agreement supports our results regarding the energy point of the liquid-gas phase transition and the onset of fragmentation.

关键词： heavy-ion collisions transport model clusterization algorithm Monte-Carlo technique li・quid-gas phase transition

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Abdominal tuberculosis of the gastrointestinal tract: Revisited

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World Journal of Gastroenterology 2014年第40期20卷 14831-14840页

作者： Uma Debi Vasudevan Ravisankar Kaushal Kishor Prasad Saroj Kant Sinha arun Kumar sharma Division of GE Radiology Department of Superspeciality of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh 160 012 India Department of Radiodiagnosis Postgraduate Institute of Medical Education and Research Chandigarh 160 012 India Division of GE Histopathology Department of Superspeciality of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh 160 012 India Department of Superspeciality of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh 160 012 India Division of GE Virology Department of Superspeciality of Gastroenterology Postgraduate Institute of Medical Education and Research Chandigarh 160 012 India

Abdominal tuberculosis is an increasingly common disease that poses diagnostic challenge,as the nonspecific features of the disease which may lead to diagnostic delays and development of *** condition is regarded as a great mimicker of other abdominal pathology.A high index of suspicion is an important factor in early *** involvement mayoccur in the gastrointestinal tract,peritoneum,lymphnodes or solid *** investigative methods have been used to aid in the diagnosis of abdominal *** diagnosis and initiation of antituberculous therapy and surgical treatment are essential to prevent morbidity and *** of the patients respond very well to standard antitubercular therapy and surgery is required only in a minority of *** plays an important role in diagnosis of abdominal tuberculosis because early recognition of this condition is *** reviewed our experience with the findings on various imaging modalities for diagnosis of this potentially treatable disease.

关键词： Tuberculosis Abdomen Extrapulmonary Gastrointestinal tract

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A HWRF-POM-TC coupled model forecast performance over North Indian Ocean: VSCS TITLI & VSCS LUBAN

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Tropical Cyclone Research and Review 2021年第1期10卷 54-70页

作者： Akhil Srivastava V.S.Prasad Ananda Kumar Das arun sharma India Meteorological Department Ministry of Earth SciencesGovernment of IndiaNew-DelhiIndia National Center for Medium Range Weather Forecasting Ministry of Earth SciencesGovernment of IndiaUttar PradeshIndia

The HWRF-POM-TC coupled model is run operationally at India Meteorological Department(IMD).This study is first attempt to assess the IMD’s operational HWRF-POM-TC(Atmosphere-Ocean)coupled model forecast performance over North Indian Ocean(NIO).The two cyclonic storms one each in Arabian Sea and Bay of Bengal were *** them,VSCS LUBAN formed over Arabian Sea(AS)and was followed by the formation of VSCS TITLI over Bay of Bengal(Bo B).It constituted a rare case whereby two VSCS have formed in the north Indian Ocean(NIO)*** HWRF-POM-TC modeling system,which was developed at National Centers for Environmental Prediction(NCEP)based on Nonhydrostatic Mesoscale Model(NMM)dynamic core,was customized for NIO *** the two storms,VSCS LUBAN&VSCS TITLI,28 and 15 consecutive 6-hourly HWRF model runs were *** HWRF-POM-TC coupled model showed great skill in forecasting of Track and Intensity for examined *** result shows that the model predicted the intensification and landfall of VSCS Luban&Titli in agreement with the best track data as made available by Cyclone Warning Division(CWD),India Meteorological Department which is also recognized as Regional Specialized Meteorological Center(RSMC)by WMO for NIO.

关键词： Ocean coupled hurricane WRF POM-TC HWRF-POM-TC

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Significant Factors for Reliability Estimation of Component Based Software Systems

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Journal of Software Engineering and Applications 2014年第11期7卷 934-942页

作者： Kirti Tyagi arun sharma Ajay Kumar Garg Engineering College Ghaziabad India Department of Information Technology Indira Gandhi Delhi Technical University for Women (IGDTUW)Kashmere Gate Delhi

Software reliability is defined as the probability of the failure-free operation of a software system for a specified period of time in a specified environment. Traditional approaches for software reliability analysis are black box approaches. These approaches use the software as a whole. At present, main emphasis of software is on reuse, hence component based software applications came into existence. Black box models are not appropriate for these applications. This paper introduces some significant factors for reliability estimation of Component Based Software Applications. Reliability of Component Based Software Application depends upon these factors. This paper?also gives the definition of factors and explains its relation with reliability of software application.

关键词： Failure Rate Reliability Component Based Systems Flexibility Operational Profile

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Pharmacological potential of Manilkara zapota(L.)***(Sapodilla):a narrative review

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Journal of Traditional Chinese Medicine 2024年第2期44卷 403-407页

作者： Priyanka sharma Aakash Deep Harish Kumar Nitin Bansal Sanjiv Kumar arun Davinder Kumar Department of Pharmaceutical Sciences Chaudhary Bansi Lal UniversityBhiwani 127021India Department of Pharmaceutical Sciences Maharishi Dayanand UniversityRohtak 124001India

Herbal medicine is safe and effective in treating various *** herbal medicine plays a tremendous role in treatment of various diseases and accompanying complications,hence herbal medicine requires remarkable attention in further research for the development of numerous active formulations for treatment of health *** plant needs special consideration for development and research of unidentified compound and characterization of novel active molecules that overcome multiple pathological *** genus Manilkara contains 135 plants around the *** overview discusses all the virtues of most important and commonly used plant Manilkara zapota(L.)***(***),also known as *** has various traditional beneficial effects in treatment of various diseases and disorders dating back to prehistoric times and used in ancient traditional system of herbal medicine.

关键词： herbal medicine Manilkara zapota phytoconstituents pharmacological activity review

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Towards Multi-Faceted Test Cases Optimization

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Journal of Software Engineering and Applications 2011年第9期4卷 550-557页

作者： Manoj Kumar arun sharma Rajesh Kumar 不详

The target of software engineering is to produce high quality software product at low cost. Software testing is labour-intensive, ambiguous and error prone activity of software development. How to provide cost-effective strategies for software test cases optimization problem such as classification, minimization, selection, and prioritization has been one of the research focuses in software testing for a long time. Many researchers and academicians have addressed the effectiveness/fitness and optimization of test cases, and obtained many interesting results. However, one issue of paramount importance in software testing i.e. the intrinsic imprecise and uncertainty of test cases fitness, fitness parameters, multi-objective optimization, is left unaddressed. Test cases fitness depends on several parameters. Vagueness of fitness of test cases and their fitness parameters have created the uncertainty in test cases optimization. Cost and adequacy values are incorporated into multi-faceted optimization of test cases. This paper argues test cases optimization requires multi-faceted optimization in order to adequately cater realistic software testing. In this paper, authors have identified several parameters for test cases fitness and multiple objectives for test cases optimization. In addition above, authors have formulated the test cases optimization problem in three different ways using multi-faceted concept. These formulations can be used in future by authors and researchers.

关键词： Multi-Faceted Optimization Test Cases Test Data Adequacy Criteria Test Case Fitness

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Generation and improvement of insulin-producing cells from differentiating embryonic stem cells for diabetes therapy

Generation and improvement of insulin-producing cells from d...

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中国生理学会第23届全国会员代表大会暨生理学学术大会

作者： arun sharma Sai Kiang Lim Joslin Diabetes Center Harvard Medical School BostonUSA Institute of Medical Biology A*STAR Singapore

Most type 1 diabetic patients rely on daily insulin injections,yet still developing cardiovascular complications. Transplantation of human pancreas or isolated islets may cure the ***,shortage of cadaveric pancreata and requirement of life-long immune suppression are 2 major obstacles in transplantation therapy of insulin-dependent *** of functional insulin-producing cells from stem cells and immunoisolation by encapsulation may circumvent the *** had generated a dozen of unlimited and glucose-responsive insulin-producing cell lines(*** and ERoSHK) from mouse embryonic stem and progenitor *** of these cells in immune deficient diabetic mice could correct *** allo-transplantation studies were carried out in immune-competent,streptozotocin-induced diabetic ***-producing(MEPI-1) cells derived from mouse embryonic progenitor cells were immunoisolated by encapsulation with alginate and peritoneally transplanted into diabetic *** glucose and insulin levels,and glucose tolerance tests were *** were washed out to determine cell functions and *** was reversed within a few days after transplantation,followed by a period of stable normoglycemic or moderate hypoglycemic levels for 2.5 months before *** reappeared immediately upon washing out of capsules.A second transplantation in relapsed mice corrected hyperglycemia as in the first *** from washed-out capsules remained the capability of glucose-stimulated insulin *** spite of fibrotic overgrowth on the capsules,the permeability of capsules seemed not *** transplantation,the number of viable cells in capsules was increased initially and then decreased to less than the transplanted cell number after 75 *** examinations showed the presence of proliferating cells and a necrotic core in the encapsulated cell clusters beyond 40 *** chang

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Mechanism of microbial spore inactivation through electromagnetic radiations:a review

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Journal of Future Foods 2024年第4期4卷 324-334页

作者： Piyush sharma arun Prasath Venugopal Parag Prakash Sutar Hong-wei Xiao Qi Zhang Deparment of Food Process Engineering.National Institute of Techmology Rourkela Odisha 769008India College of Engineering China Agriculural UniversityBeijing 100083China School of Mechanical Engineering Yangzhou UTniversiny Yangzhou 225002China

Spores are the biological structures formed out of sporulation from vegetative cells in adverse *** tolerant to many extreme environment and conditions,they escape and survives critical processing steps in the food industry that poses food and health safety problems,as is evident from the increase in reports of food-bome outbreaks due to *** radiation(EM)is used for rapid decontamination and sterilization purposes in the food *** studies have reported a greater reduction in spore population upon irradiation with EM rays due to its impact on genomic material and other components of spores that destabilises overall structue and brings clonogenic death However,there is scattered literature regarding the mechanism of its inactivation and resistance against such *** review attempts to concisely evaluate the potential of electromagnetic radiations in spore inactivation and details its mechanism through a collective study of scientific results and *** also briefs about the process of sporulation,the structure of spores and the role of its components in the resistance of spores to *** studies,which demonstrated that combining various EM treatments might be an effective way for inactivation of spores,were discussed in detail.

关键词： Spore structure Electromagnetic radiations Mechanism of inactivation Damage resistance

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