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Anti-inflammatory mechanism of electroacupuncture involves the modulation of multiple systems,levels and targets and is not limited to“driving the vagus-adrenal axis”

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Journal of Integrative Medicine 2023年第4期21卷 320-323页

作者： arthur Yin Fan American TCM Association ViennaVA 22182USA McLean Center for Complementary and Alternative Medicine PLCViennaVA 22182USA

In October 2021,an international collaborative study on the use of electroacupuncture(EA)to treat inflammation was published in the journal Nature by *** Ma’s *** on the results of EA on inflammation in the mouse model of lipopolysaccharide inflammatory storm,the study showed that the distal effect of acupuncture can be achieved by“driving the vagus-adrenal axis(through the adrenal medulla,by releasing catecholamines).”PROKR2Cre-marked sensory neurons,which innervate the deep hindlimb fascia but not the abdominal fascia,are crucial for driving this *** study suggests the existence of specificity distribution of acupoints,that different EA stimulation intensities or different needle penetration depths have different therapeutic effects,that photosensitive stimulation may be a substitute for needle acupuncture,and that massage,stretching and body movements may also activate PROKR2Cremarkable dorsal root ganglion sensory neurons and elicit anti-inflammatory ***,results of some other studies are contrary to the conclusions of Ma’s *** examples:low-intensity EA at GB30 point significantly reduced the inflammation in the rat model of persistent inflammation,which is more relevant to the real daily acupuncture practice,and this effect was partly related to the adrenal cortex and associated with the stimulation of corticosterone and adrenocorticotropic hormone;manual acupuncture(similar to the low-intensity EA)at KI3,Zhichuan point(an extra point),*** effective in a severe COVID-19 patient with sepsis;stimulating ST25 with low-intensity EA or manual acupuncture was effective against gastrointestinal inflammations;the above mentioned points are not in an area enriched with PROKR2Cre-marked sensory nerve *** shows that the mechanism of EA against inflammation includes modulating multi-systems,multi-levels and multi-targets,which does not limit to“driving the vagus-adrenal axis.”

关键词： Electric acupuncture Acupuncture Anti-inflammation Mechanism Adrenal Autonomic nerves

Expediting the transition from replacement medicine to tissue engineering

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Regenerative Biomaterials 2016年第2期3卷 111-113页

作者： arthur J.Coury Department of Chemical Engineering Northeastern UniversityBostonMAUSA

In this article,an expansive interpretation of“Tissue Engineering”is proposed which is in congruence with classical and recent published definitions.I further simplify the definition of tissue engineering as:“Exerting systematic control of the body’s cells,matrices and fluids.”As a consequence,many medical therapies not commonly considered tissue engineering are placed in this category because of their effect on the body’s *** the progress of tissue engineering strategies is inexorable and generally positive,it has been subject to setbacks as have many important medical *** practice is currently undergoing a transition on several fronts(academics,start-up companies,going concerns)from the era of“replacement medicine”where body parts and functions are replaced by mechanical,electrical or chemical therapies to the era of tissue engineering where health is restored by regeneration generation or limitation of the body’s tissues and functions by exploiting our expanding knowledge of the body’s biological processes to produce natural,healthy outcomes.

关键词： tissue engineering medical devices combination products regenerative medicine

Degree of nutrient consumption as an aging index of upwelling or vertically mixed water in the northern Taiwan Strait

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Acta Oceanologica Sinica 2005年第1期24卷 115-124页

作者： CHEN Chentung arthur HSING Liyu Institute of Marine Geology and Chemistry National Sun Yat-sen University Kaohsiung ChinaInstitute of Marine Geology and Chemistry National Sun Yat-sen University Kaohsiung China

In order to determine the relative aging status of upwelled or vertically mixed water in the northern Taiwan Strait, a recently developed method of calculating the degree of nutrient consumption (DNC) was employed. Upwelling was detected at a water depth of about 75 m in summer. Bottom waters in the aphotic zone and newly-upwelled waters in the euphoric zone were found to be low in terms of their DNC. In general, a low DNC was noted alongside the other traditional upwelling indicators, such as lower temperature and degree of oxygen saturation, but higher salinity, apparent oxygen utilization, nutrient contents and chlorophyll-a. Enhanced vertical mixing, but without an apparent upwelling signal, was detected near the same location in winter.

关键词： upwelling degree of nutrient consumption Taiwan Strait dissolved organic nitrogen dissolved organic phosphorus

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赛马“银光”

疯狂英语（新悦读） 2024年第3期 42-44,76页

作者：阿瑟·柯南·道尔不详

作品简介:侦探必须眼观六路,耳听八方,还得记住与案件相关的所有细节。他们必须通晓人情世故,对狗、羊和马都得有所知。甚至,他们还必须了解赛马这项帝王的娱乐运动……一匹著名赛马——“银光”——失踪了,夏洛克·福尔摩斯和华生医生... 详细信息

作品简介:侦探必须眼观六路,耳听八方,还得记住与案件相关的所有细节。他们必须通晓人情世故,对狗、羊和马都得有所知。甚至,他们还必须了解赛马这项帝王的娱乐运动……一匹著名赛马——“银光”——失踪了,夏洛克·福尔摩斯和华生医生来到了位于达特穆尔的马厩。

关键词：作品简介人情世故赛马银光娱乐运动

Pitfalls in Assessing Risks from Carcinogens

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Biomedical and Environmental Sciences 1991年第3期4卷 242-249页

作者： arthur FURST Institute of Chemical Biology University of San Francisco San Francisco CA 94117-1080

The decision to classify a chemical as a human carcinogen must depend upon agreed conclusions from epidemiology, bioassays, and some short-term corroborating tests; information from only one of these disciplines is inadequate. Most pitfalls appear in interpreting the results from animal bioassays; this report will concentrate on them. Often the conclusion is accepted that a chemical is an animal carcinogen without a critical appraisal of the experimental design. By manipulating the experiment, 90 + % of all chemicals can induce some tumor in a rodent. Pitfalls encountered in bioassays result from not specifying the exact agent under test and how it relates to human exposure, using inappropriate routes of administration unrelated to humans, administering illogically high doses, or concluding that a cancer was induced without adequate histopathological description of the lesion. Importance of animal husbandry is often overlooked. Pitfalls are also related to short-term tests. Finally, a major pitfall in assessing carcinogenic risk from chemicals is drawing global conclusions about the carcinogenicity of an agent after the detection of only one or two tumors in the treated group.

关键词： Pitfalls in Assessing Risks from Carcinogens

Duality of graph invariants

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Science China Mathematics 2020年第8期63卷 1613-1626页

作者： Kaifeng Bu Weichen Gu arthur Jaffe Harvard University CambridgeMA 02138USA School of Mathematical Science Zhejiang UniversityHangzhou 310027China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100080China

We study a new set of duality relations between weighted,combinatoric invariants of a graph *** dualities arise from a non-linear transform B,acting on the weight function *** define B on a space of real-valued functions O and investigate its *** show that three invariants(the weighted independence number,the weighted Lovasz number,and the weighted fractional packing number)are fixed points of B^2,but the weighted Shannon capacity is *** interpret these invariants in the study of quantum non-locality.

关键词： duality graph invariants quantum non-locality

Evidence-based Practice of Chinese Medicine in Physical Rehabilitation Science

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Chinese Journal of Integrative Medicine 2013年第10期19卷 723-729页

作者： arthur de Sá Ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Program of Rehabilitation ScienceCentro Universitario Augusto MottaRio de JaneiroRJBrazil(21041-021) Department of Physical Therapy UniversidadeSalgado de OliveiraNiteróiRJBrazil(21041-021)

Chinese medicine is among other traditional medical systems practiced either as a coadjutant intervention to Greek medicine or as the unique therapeutic intervention for illness prevention, treatment or rehabilitation. The complete spectrum from that traditional system includes acupuncture and moxibustion, herbal and food therapy, massage therapy （tuina）, physical exercises （taijiquan）, and breathing exercises （qigong）. In this article, it is presented several randomized controlled trials and systematic reviews on the application of all therapeutic modalities from Chinese medicine in the physical rehabilitation scenario. The discussed studies encompasses both ＂positive＂ and ＂negative＂ results of Chinese medicine intervention for disabilities due to illnesses of the nervous, musculoskeletal or cardiovascular systems. Additionally, the importance of the personalized approach for Chinese medicineand rehabilitation is emphasized together with the need for reproducible methods for pattern differentiation and intervention selection. Chinese medicine resources are recognized as promising methods for therapeutic rehabilitation and can be incorporated into the rehabilitation science. The wide variety of therapeutic resources explains why Chinese medicine is currently a multidisciplinary practice for health protection and promotion, early diagnosis and treatment as well as rehabilitation with roles in the public health care system.

关键词： rehabilitation physical therapy Chinese medicine

Distribution of licensed acupuncturists and educational institutions in the United States in early 2015

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Journal of Integrative Medicine 2018年第1期16卷 1-5页

作者： arthur Yin Fan Sarah Faggert McLean Center for Complementary and Alternative Medicine PLC Vienna VA 22182 USA American Traditional Chinese Medicine Association Vienna VA 22182 USA

In recent decades, acupuncture has been used more widely and extensively in the United States （U.S.）. However, there have been no national surveys or analyses reported in academic journals on the number of practicing or licensed acupuncturists, This study was conducted to identify the approximate number of licensed acupuncturists active in 2015. The Board of Acupuncture or Board of Medicine in each state or U.S. territory was contacted to collect data, Online license information searching was also performed in order to get accurate numbers of licensed acupuncturists for those states in which a board was unable to be contacted. The study found that the number of licensed acupuncturists in 2015 in the U,S, was 34,481. Of this, more than 50% were licensed in three states alone： California （32.39%）, New York （11,89%） and Florida （7.06%）. The number of licensed acupuncturists increased 23.30% and 52.09%, compared to the year 2009 （n = 27,965） and 2004 （n = 22,671）, respectively; increasing about 1,266 per year. There were 62 and 10 accredited acupuncture institutions providing master and doctoral degrees, respectively. The West Coast comprised 51.39% of degree granting programs, while the East Coast comprised 29.17%; together the coastal states housed more than 80% of all programs, with the remainder sprinkled across the southern （9.72%）, northern （8.33%）, and the middle/central states （1.39%）. Forty-four states and the District of Columbia regulated acupuncture practice by law at the time of data collection. Acupuncture continues to be a quickly growing profession in the U.S,

关键词： Acupuncturist Acupuncture educational institution Acupuncture regulation Oriental medicine United States

Holographic software for quantum networks

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Science China Mathematics 2018年第4期61卷 593-626页

作者： arthur Jaffe Zhengwei Liu Alex Wozniakowski Departments of Mathematics and Physics Harvard UniversityCambridgeMA 02138USA School of Physical and Mathematical Sciences and Complexity Institute Nanyang Technological UniversitySingapore 637723Singapore

We introduce a pictorial approach to quantum information, called holographic software. Our software captures both algebraic and topological aspects of quantum networks. It yields a bi-directional dictionary to translate between a topological approach and an algebraic approach. Using our software, we give a topological simulation for quantum networks. The string Fourier transform(SFT) is our basic tool to transform product states into states with maximal entanglement entropy. We obtain a pictorial interpretation of Fourier transformation, of measurements, and of local transformations, including the n-qudit Pauli matrices and their representation by Jordan-Wigner transformations. We use our software to discover interesting new protocols for multipartite communication. In summary, we build a bridge linking the theory of planar para algebras with quantum information.

关键词： quantum information picture language string Fourier transform Clifford gate multipartite entanglement quantum protocol