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Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care

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Journal of Integrative Medicine 2021年第5期19卷 460-466页

作者： Xin yin Shu-bin Cai Lan-ting Tao Lu-ming Chen Zhong-de Zhang Su-hong Xiao arthur yin fan Xu Zou Department of Critical Care Medicine Second Clinical CollegeGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Department of General Medicine No.3 Division Second Clinical CollegeGuangzhou University of Chinese Medicine.Guangzhou 510120Guangdong ProvinceChina Department of Emergency Medicine Second Clinical CollegeGuangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina Second Clinical College Guangzhou University of Chinese MedicineGuangzhou 510120Guangdong ProvinceChina SH Clinic for Acupuncture&Chinese Medicine Indianapolis.IN 46268USA TCM American Alumni Association(TCMAAA) IndianapolisIN 46268USA American TCM Association(ATCMA) ViennaVA 22182USA McLean Center for Complementary and Alternative Medicine PLCViennaVA 22182USA

There is currently no drug or therapy that can cure the coronavirus disease 2019(COVID-19), which is highly contagious and can be life-threatening in severe cases. Therefore, seeking potential effective therapies is an urgent task. An older female at the Leishenshan Hospital in Wuhan, China, with a severe case of COVID-19 with significant shortness of breath and decrease in peripheral oxygen saturation(SpO_(2)),was treated using manual acupuncture and Chinese herbal medicine granule formula Fuzheng Rescue Lung with Xuebijing Injection in addition to standard care. The patient’s breath rate, SpO_(2), heart rate,ratio of neutrophil/lymphocyte(NLR), ratio of monocyte/lymphocyte(MLR), C-reactive protein(CRP),and chest computed tomography were monitored. Acupuncture significantly improved the patient’s breathing function, increased SpO_(2), and decreased her heart rate. Chinese herbal medicine might make the effect of acupuncture more stable;the use of herbal medicine also seemed to accelerate the absorption of lung infection lesions when its dosage was increased. The combination of acupuncture and herbs decreased NLR from 14.14 to 5.83, MLR from 1.15 to 0.33 and CRP from 15.25 to 6.01 mg/L. These results indicate that acupuncture and Chinese herbal medicine, as adjuvants to standard care, might achieve better results in treating severe cases of COVID-19.

关键词： COVID-19 Severe case Case report Acupuncture Chinese herbal medicine Integrative therapy

Decoding an Old 1907 Prescription of *** Hay(“Doc Hay”):One of the Earliest Chinese Medicine Doctors in the United States

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Chinese Medicine and Culture 2020年第4期3卷 232-240页

作者： arthur yin fan Louis Lei Jin Boling Huang Mingxia Yu Xiaoyin Zhao Sarah Faggert Alem American TCM Association McLean Center for Complementary and Alternative Medicine PLCVienna International Institute of Systems Medicine Inc.MilwaukeeWI 53222USA Nanjing Institute of Chinese Medicine Nanjing University of Chinese Medicine the Third HospitalNanjingChina Eastern Roots Wellness PLCMcLeanVA 22101

Objectives:Chinese medicine doctors have practiced in the United States since April of 1854,the world's first Chinese medicine doctor's memorial is Kam Wah Chung Museum in John Day,Oregon,U.S.,to commemorate *** Hay(“Doc Hay”伍于念)and his business partner Lung On(梁光荣).There were few studies to explore Doc Hay's real practice and prescription,while most of papers focused on Doc Hay's legend *** paper aims to analyze and interpret one of the intriguing herbal prescriptions that Doc Hay had *** and Methods:*** yin fan made an academic travel to Kam Wah Chung museum on August 5,2018 and examined the books and hand-written prescriptions of Doc Hay,which were not exhibited to the public at that *** paper analyzes and interprets one of herbal prescriptions that Doc Hay had hand-written in *** process included four steps:(1):Transform Doc Hay's hand-written prescription(with original herb names)to standard herb names in Chinese.(2):Induct and rearrange the herb name into groups based on herb property characteristics and then translate them into both Pinyin names and English *** of the prescription may include in what classic formula(s)routinely introduced in Chinese medicine textbooks.(3):Analyze the herbal action for each group and potential symptoms or conditions the patient may have *** analysis of classic formula(s)used in the prescription may represent what clinical condition was being treated at that time.(4):Combine the analysis to give a comprehensive picture of the ***:The prescription consists of 67 herbs,total 934.6 grams,and including yin Qiao Powder(银翘散),Sang Ju Decoction(桑菊饮),Zhi Sou Powder(止嗽散),Qing ying Decoction(清营汤),Xi Jiao Di Huang Decoction(犀角地黄汤),Long Dan Xie Gan Decoction(龙胆泻肝汤)and Chai Hu Shu Gan Powder(柴胡疏肝散).Speculation indicated that the prescription was for a patient who had obvious pulmonary infection accompanied by severe cough,and probably had prolonged pulmonary

关键词： Prescription composition Ing Hay(伍于念) Kam Wah Chung(金华昌) epidemic disease Spanish flu COVID-19

Discussions on real-world acupuncture treatments for chroni clow-back pain in older adults

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Journal of Integrative Medicine 2019年第2期17卷 71-76页

作者： arthur yin fan Hui Ouyang Xinru Qian Hui Wei David Dehui Wang Deguang He Haihe Tian Changzhen Gong Amy Matecki Sarah Faggert Alemi American TCM Association (ATCMA) McLean Center for Complementary and Alternative Medicine PLC yin & YANG Healthcare Rusk Rehabilitation at NYU Langone Health Wei’s Chinese Medical Center Ohio State Integrative Medicine Wexner Medical Center Ohio State University New England School of Acupuncture Chinese Acupuncture and Herbs Center American Academy of Acupuncture & Oriental Medicine Division of Integrative Medicine Alameda Health System Affiliated with School of Medicine University of California San Francisco Eastern Roots Wellness PLC

Chronic low-back pain(CLBP) is one of the most common pain conditions. Current clinical guidelines for low-back pain recommend acupuncture for CLBP. However, there are very few high-quality acupuncture studies on CLBP in older adults. Clinical acupuncture experts in the American Traditional Chinese Medicine Association(ATCMA) were interested in the recent grant on CLBP research announced by the National Center for Complementary and Integrative Health. The ATCMA experts held an online discussion on the subject of real-world acupuncture treatments for CLBP in older adults. Seven participants, each with more than 20 years of acupuncture practice, discussed their own unique clinical experience while another participant talked about the potential mechanism of acupuncture in pain management. As a result of the discussion, a picture of a similar treatment strategy emerged across the participants for CLBP in older adults. This discussion shows that acupuncture may have complicated mechanisms in pain management, yet it is effective for the treatment of chronic pain involving maladaptive neuroplasticity;therefore, it should be effective for CLBP in older adults.

关键词： Acupuncture Pragmatic clinical trials as topic Real world Treatment strategies Low-back pain Older adults Discussion

Dr. Wu： A beautiful, moving and meditative song-- In memory of Dr. Jing Nuan Wu, a pioneer of acupuncture and a Chinese medicine doctor in the United States

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中西医结合学报 2012年第8期10卷 837-840页

作者： arthur yin fan Ziyi fan McLean Center for Complementary and Alternative Medicine PLC. Vienna VA 22182 USA. ArthurFan@ChineseMedicineDoctor.US

Few popular songs arc titled a doctor's name and even fewer are sung directly by the doctor's ***,the song *** might be the *** sung by Steely Dan[1],a well-known American jazz-rock band,*** has been loved by many Americans for over 35 *** beautiful,moving,and meditative song was written in 1975 after Steely Dan had abandoned touring and reconvened in Los Angles,the United State[2].

关键词：摘要编辑部编辑工作读者

Effectiveness of two different acupuncture strategies in patients with vulvodynia Study protocol for a pilot pragmatic controlled trial

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Journal of Integrative Medicine 2018年第6期16卷 384-389页

作者： arthur yin fan Sarah F.Alemi yingping H.Zhu Sudaba Rahimi Hui Wei Haihe Tian Deguang He Changzhen Gong Guanhu Yang Chong He Hui Ouyang American Traditional Chinese Medicine Association ViennaVA 22182USA McLean Center for Complementary and Alternative Medicine PLC.ViennaVA 22182USA

Background： Vulvodynia, or vulvar pain, is a common condition in women; however, there are few evidence-based clinical trials evaluating nonpharmacological therapies for this condition. Acupuncture is one complementary and integrative medicine therapy used by some patients with vulvodynia. This study evaluates two different acupuncture strategies for the treatment of vulvodynia and aims to evalu- ate whether either of the acupuncture protocols reduces vulvar pain, pain duration or pain with inter- course. The study also examines how long the effect of acupuncture lasts in women with vulvodynia. Methods/design： The study is designed as a randomized controlled trial, focused on two acupuncture protocols. Fifty-one patients who have had vulvodynia for more than 3 months will be recruited. Among them, 34 patients will be randomized into Groups la and 1b; those who are unwilling to receive acupuncture will be recruited into the standard care group （Group 2）. Patients in Group la will have acupuncture focused on the points in the pudendal nerve distribution area, while patients in Group lb will receive acupuncture focused on traditional （distal） meridian points. Patients in Group 2 will receive routine conventional treatments, such as using pain medications, local injections and physical therapies or other nonsurgical procedures. Acupuncture will last 45 min per session, once or twice a week for 6 weeks. The primary outcome measurement will be objective pain intensity, using the cotton swab test. The secondary outcome measurement will be subjective patient self-reported pain intensity, which will be conducted before cotton swab test. Pain intensities will be measured by an 11-point Numeric Pain Rating Scale. Pain duration and pain score during intercourse are recorded. Local muscle tension, tender- ness and trigger points （Ashi points） are also recorded. All measurements will be recorded at baseline （before the treatment）, at the end of each week during treatment and at t

关键词： Acupuncture Vulvodynia Meridian points Pudendal nerve Study protocol

Acupuncture price in forty-one metropolitan regions in the United States: An out-of-pocket cost analysis based on Ok ***

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Journal of Integrative Medicine 2019年第5期17卷 315-320页

作者： arthur yin fan David Dehui Wang Hui Ouyang Haihe Tian Hui Wei Deguang He Changzhen Gong Jipu Wen Ming Jin Chong He Sarah Faggert Alemi Sudaba Rahimi Acupuncture Profession Survey Project American Traditional Chinese Medicine AssociationViennaVA 22182USA Tongrentang Ming Qi Clinic New YorkNY 10016USA Oriental Asclepius LLCPlantationFL 33317USA Eastern Roots Wellness PLCMcLeanVA 22101USA McLean Center for Complementary and Alternative Medicine PIC.ViennaVA 22182USA Ohio State Integrative Medicine Wexner Medical CenterOhio State UniversityColumbusOH 43221USA yin & YANG Healthcare FriendswoodTX 77546USA Chinese Acupuncture and Herbs Center LargoFI 33778USA Wei's Chinese Medical Center Lake WorthFL 33467USA New England School of Acupuncture NewtonMA 02458USA American Academy of Acupuncture Oriental Medicine RosevilleMN 55113USA TCMzone TempeAZ 85281USA

Few studies have focused on the cost of acupuncture treatments although acupuncture has become popular in the United States(U.S.). The purpose of the current study was to examine the out-of-pocket costs incurred from acupuncture services based on an online website, Ok ***. We examined descriptive statistics(range, median and 20% intervals) for the cost of acupuncture "first-time visits"and "follow-up visits" in 41 metropolitan regions in the U.S. The acupuncture prices of 723 clinics throughout 39 metropolitan regions were included, except for Birmingham, Alabama and Detroit, Michigan as there was no online data available at the time of the study for these two regions. The cost range for a first-time acupuncture visit was $15–400;the highest median was $150 in Charleston, South Carolina,while the lowest was $45 in St. Louis, Missouri. The top 10 cities for the highest median were:Baltimore, Washington, D.C., New York, San Francisco, San Jose, Boston, Atlanta, Seattle, Portland and Indianapolis, with the median $120, while the median for all 723 clinics was $112. For the follow-up visits,the cost range was $15–300;the highest median was $108 in Charleston, South Carolina, and the lowest$40 in Miami, Florida. The 10 cities with highest median follow-up acupuncture visit costs were: New York, Baltimore, New Orleans, Washington, D.C., Philadelphia, San Francisco, San Jose, Seattle, Boston and Atlanta, with the median $85, while for all 723 clinics the median price was $80. The estimation of the average gross annual income of each acupuncturist from the regions studied was $95,760, while the total annual cost of patients seeking acupuncture services in the U.S. was about $3.5 billion in 2018.

关键词： Acupuncture Price Out-of-pocket cost Annual cost City, United States

Acupuncture's Role in Solving the Opioid Epidemic: Evidence, Cost-Effectiveness, and Care Availability for Acupuncture as a Primary, Non-Pharmacologic Method for Pain Relief and Management-White Paper 2017

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Journal of Integrative Medicine 2017年第6期15卷 411-425页

作者： arthur yin fan david w.miller bonnie bolash matthew bauer john mcdonald sarah faggert hongjian he yong ming li amy matecki lindy camardella mel hopper koppelman jennifer a.m.stone lindsay meade john pang the american tcm association ViennaVA 22182USA the american society of acupuncturists ChicagoIL 60618USA the joint acupuncture opioid task force La VerneCA 91750USA pacific college of oriental medicine ChicagoIL 60601USA the acupuncture now foundation CA 91750USA the acupuncture evidence project ProvidenceRI 02860USA the acupuncture society of virginia ViennaVA 22182USA the national federation of chinese tcm organizations New YorkNY 11501USA the american alliance for professional acupuncture safety GreenwichCT 06878USA the american traditional chinese medicine society New YorkNY 11501USA highland hospital alameda health systemOaklandCA 94602USA indiana university school of medicine IndianapolisIN 46202USA university of california san diego school of medicineSan DiegoCA 92093USA

The United States （U.S.） is facing a national opioid epidemic, and medical systems are in need of non- pharmacologic strategies that can be employed to decrease the public＇s opioid dependence. Acupuncture has emerged as a powerful, evidence-based, safe, cost-effective, and available treatment modality suitable to meeting this need. Acupuncture has been shown to be effective for the management of numerous types of pain conditions, and mechanisms of action for acupuncture have been described and are understandable from biomedical, physiologic perspectives. Further, acupuncture＇s cost-effectiveness can dramatically decrease health care expenditures, both from the standpoint of treating acute pain and through avoiding addiction to opioids that requires costly care, destroys quality of life, and can lead to fatal overdose. Numerous federal regulatory agencies have advised or mandated that healthcare systems and providers offer non-pharmacologic treatment options for pain. Acupuncture stands out as the most evidence-based, immediately available choice to fulfil these calls. Acupuncture can safely, easily, and cost-effectively be incorporated into hospital settings as diverse as the emergency department, labor and delivery suites, andneonatal intensive care units to treat a variety of commonly seen pain conditions. Acupuncture is already being successfully and meaningfully utilized by the Veterans Administration and various branches of the U.S. Military, in some studies demonstrably decreasing the volume of opioids prescribed when included in care.

关键词： acupuncture opioid epidemic pain opiate dependency effectiveness safety cost-effectiveness mechanism United States

Flexible Strain Sensors with Ultra‑High Sensitivity and Wide Range Enabled by Crack‑Modulated Electrical Pathways

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Nano-Micro Letters 2025年第3期17卷 246-264页

作者： Yunzhao Bai Yunlei Zhou Xuanyu Wu Mengfei yin Liting yin Shiyuan Qu fan Zhang Kan Li YongAn Huang State Key Laboratory of Intelligent Manufacturing Equipment and Technology Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China Flexible Electronics Research Center Huazhong University of Science and TechnologyWuhan 430074People’s Republic of China Hangzhou Institute of Technology Xidian UniversityHangzhou 311200People’s Republic of China School of Mechano‑Electronic Engineering Xidian UniversityXi’an 710071People’s Republic of China Department of Aerospace and Mechanical Engineering University of Southern CaliforniaLos AngelesCA 90089USA

This study presents a breakthrough in flexible strain sensor technology with the development of an ultrahigh sensitivity and wide-range sensor,addressing the critical challenge of reconciling sensitivity with measurement *** by the structure of bamboo slips,we introduce a novel approach that utilises liquid metal to modulate the electrical pathways within a cracked platinum fabric *** resulting sensor demonstrates a gauge factor greater than 108 and a strain measurement capability exceeding 100%.The integration of patterned liquid metal enables customisable tuning of the sensor’s response,while the porous fabric structure ensures superior comfort and air permeability for the *** design not only optimises the sensor’s performance but also enhances the electrical stability that is essential for practical *** systematic investigation,we reveal the intrinsic mechanisms governing the sensor’s response,offering valuable insights for the design of wearable strain *** sensor’s exceptional performance across a spectrum of applications,from micro-strain to large-strain detection,highlights its potential for a wide range of real-world uses,demonstrating a significant advancement in the field of flexible electronics.

关键词： Flexible strain sensor Fabric Crack Response regulation Epidermal device

Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： Ming‑Yuan Yu Jing Wu Guang yin fan‑Zhen Jiao Zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods