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Masquelet technique in military practice:specificities and future directions for combat-related bone defect reconstruction

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Military Medical Research 2023年第3期10卷 369-382页

作者： laurent Mathieu Romain Mourtialon Marjorie Durand arnaud de Rousiers Nicolas de l’Escalopier Jean‑Marc Collombet Department of Orthopedic Trauma and Reconstructive SurgeryPercy Military Hospital101 avenue Henri Barbusse92140 ClamartFrance Department of Surgery Ecole du Val‑de‑GrâceFrench Military Health Service Academy1place Alphonse Laveran75005 ParisFrance Military Biomedical Research Institute(IRBA) 1 place Général Valérie André91220 Brétigny‑sur‑OrgeFrance

Because of its simplicity,reliability,and replicability,the Masquelet induced membrane technique(IMT)has become one of the preferred methods for critical bone defect reconstruction in *** it is now used worldwide,few studies have been published about IMT in military *** reconstruction is particularly challenging in this context of care due to extensive soft-tissue injury,early wound infection,and even delayed management in austere *** on our clinical expertise,recent research,and a literature analysis,this narrative review provides an overview of the IMT application to combat-related bone *** presents technical specificities and future developments aiming to optimize IMT outcomes,including for the management of massive multi-tissue defects or bone reconstruction performed in the field with limited resources.

关键词： Bone defect Induced membrane technique Gunshot wound Low resources Masquelet technique Military War surgery

Removing harvest residues from hardwood stands affects tree growth, wood density and stem wood nutrient concentration in European beech (Fagus sylvatica) and oak (Quercus spp.)

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Forest Ecosystems 2022年第2期9卷 147-159页

作者： Sanjoy Roy Jean-Michel Leban Bernhard Zeller Gregory van der Heijden arnaud Reichard Marie-Christine Gehin Philippe Santenoise laurent Saint-Andre INRAE BEFF-54000 NancyFrance IGN Laboratoire de l’Inventaire ForestierNancyF-54000France Universite de Lorraine AgroParisTechINRAESILVAF-54000 NancyFrance

Background:Higher exportation of harvest residues from forests due to increased demand for woody biomass,has reportedly diminished soil mineral resources and may lead to degraded tree nutrition as well as ***,as nutrients become less available in the soil,the remobilization of nutrients in biomass tissues(plant internal cycling)helps sustain tree *** study aims to quantify the impact of Removing Harvest Residues and Litter(RHRL)during five years on tree growth,wood density,and stem wood nutrient concentrations in young beech and oak forest ***:Our study found that,RHRL significantly decreased tree growth ring width by 14%,and wood density by 3%,in beech trees,in near bark *** also significantly reduced nutrient concentration in near bark and near pith areas of both studied ***,Na and S were found lower by 44%,76%,and 56%,respectively,in near bark area of beech *** near bark area of oak trees,K,Ca,Mg,Na,S,and Fe were lower by 20%,25%,41%,48%,41%,and 16%,respectively.K and Mg concentrations decreased more strongly in near pith area compared to near bark area suggesting internal translocation of these two ***:In beech trees,wood density proved to be an important factor while quantifying the effect of removing harvest residuals on tree growth and *** nutrient loss intensified the remobilization of nutrients con-tained in older tree rings(close to the pith)towards newly formed rings(close to bark).In our study,in beech trees,K was found to be the most recycled major *** results demonstrate the potential of such analysis for providing valuable insight into the effect of RHRL in premature stands on the physiological adaptive strategies of trees and an indication of soil fertility status.

关键词： Harvest residues Fagus sylvatica Quercus petraea Dendroecology Dendrochemistry Radial growth Wood density Tree growth Ring width Translocation

Rapid prototyping of a polymer MEMS dropletdispenser by laser-assisted 3D printing

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Microsystems & Nanoengineering 2023年第4期9卷 211-221页

作者： Rémi Courson Oleksii Bratash Ali Maziz CloéDesmet Ricardo Alvarado Meza Loïc Leroy Elodie Engel arnaud Buhot laurent Malaquin Thierry Leïchlé LAAS-CNRS Universitéde ToulouseCNRS31400 ToulouseFrance UniversitéGrenoble Alpes CNRSCEAIRIGSyMMES38000 GrenobleFrance Georgia Tech−CNRS International Research Laboratory AtlantaGA 30332USA

In this work, we introduce a polymer version of a previously developed silicon MEMS drop deposition tool for surfacefunctionalization that consists of a microcantilever integrating an open fluidic channel and a reservoir. The device isfabricated by laser stereolithography, which offers the advantages of low-cost and fast prototyping. Additionally,thanks to the ability to process multiple materials, a magnetic base is incorporated into the cantilever for convenienthandling and attachment to the holder of a robotized stage used for spotting. Droplets with diameters ranging from∼50 μm to ∼300 μm are printed upon direct contact of the cantilever tip with the surface to pattern. Liquid loading isachieved by fully immersing the cantilever into a reservoir drop, where a single load results in the deposition of morethan 200 droplets. The influences of the size and shape of the cantilever tip and the reservoir on the printing outcomeare studied. As a proof-of-concept of the biofunctionalization capability of this 3D printed droplet dispenser,microarrays of oligonucleotides and antibodies displaying high specificity and no cross-contamination are fabricated,and droplets are deposited at the tip of an optical fiber bundle.

关键词： cantilever reservoir printing

Moisture-Induced Non-Equilibrium Phase Segregation in Triple Cation Mixed Halide Perovskite Monitored by In Situ Characterization Techniques and Solid-State NMR

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Energy & Environmental Materials 2023年第2期6卷 185-194页

作者： Mohammad Ali Akhavan Kazemi Nicolas Folastre Parth Raval Michel Sliwa Jean Marie Vianney Nsanzimana Sema Golonu arnaud Demortiere Jean Rousset Olivier Lafon laurent Delevoye G.N.Manjunatha Reddy Frédéric Sauvage Laboratoire de Réactivité et Chimie des Solides(LRCS) UMR CNRS 7314-Institut de Chimie de Picardie FR 3085Université de Picardie Jules Verne33 rue Saint LeuAmiens Cedex FR-80039France CNRS Centrale LilleUMR 8181UCCSUnitéde Catalyse et Chimie du SolideUniversité de LilleUniversitéd’ArtoisLille F-59000France UMR 8516-LASIRE-Laboratoire de Spectroscopie pour les Interactions la Réactivité et l’EnvironnementCNRSUniversitéde LilleLille F-59000France EDF R&D EDF LabBoulevard Gaspard MongePalaiseau 91120France

Environmental stability is a major bottleneck of perovskite solar *** a handful of studies are investigating the effect of moisture on the structural degradation of the *** mostly rely on ex situ experiments and on completely degraded samples,which restrict the assessment on initial and final *** combining in situ X-ray diffraction under controlled 85%relative humidity,and live observations of the water-induced degradation using liquid-cell transmission electron microscopy,we reveal two competitive degradation paths leading on one hand to the decomposition of state-of-theart mixed cation/anion(Cs_(0.05)(MA_(0.17)FA_(0.83))_(0.95)Pb(Br_(0.17)I_(0.83))_(3)(CsMAFA)into PbI_(2) through a dissolution/recrystallization mechanism and,on the other hand,to a non-equilibrium phase segregation leading to CsPb_(2)Br_(5) and a Cesium-poor/iodide-rich Cs_(0.05)-x(MA_(0.17)FA_(0.83))_(0.95)Pb(Br_(0.17-2y)I_(0.83)+2y)_(3) *** degradation mechanism is corroborated at atomic-scale resolution through solid-state ^(1)H and ^(133)Cs NMR *** to moisture leads to a film containing important heterogeneities in terms of morphology,photoluminescence intensities,and *** results provide new insights and consensus that complex perovskite compositions,though very performant as champion devices,are comparatively metastable,a trait that limits the chances to achieve long-term stability.

关键词： liquid-cell transmission electron microscopy moisture degradation perovskite stability phase segregation solid-state NMR

HACD1,a regulator of membrane composition and fluidity,promotes myoblast fusion and skeletal muscle growth

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分子细胞生物学报:英文版 2015年第5期7卷 429-440页

作者： Jordan Blondelle Yusuke Ohno Vincent Gache Stephane Guyot Sebastien Storck Nicolas Blanchard-Gutton Ines Barthelemy Gemma Walmsley Anaelle Rahier Stephanie Gadin Marie Maurer laurent Guillaud Alexandre Prola arnaud Ferry Genevieve Aubin-Houzelstein Jean Demarquoy Frederic Relaix Richard JPiercy Stephane Blot Akio Kihara laurent Tiret Fanny Pilot-Storck Inserm IMRB U955-E1094000 CreteilFrance Universite Paris-Est Ecole nationale veterinaire d’Alfort(EnvA)94700 Maisons-AlfortFrance Universite Paris-Est Creteil Faculte de medecine94000 CreteilFrance Laboratory of Biochemistry Faculty of Pharmaceutical SciencesHokkaido UniversitySapporo 060-0812Japan Universite de Bourgogne UMR A 02.102 PAM-EPMBAgroSup Dijon21000 DijonFrance Institut Necker-Enfants Malades INSERM U1151-CNRS UMR 8253Sorbonne Paris CiteUniversite Paris DescartesFaculte de Medecine-Site Broussais75015 ParisFrance Comparative Neuromuscular Disease Laboratory Department of Clinical Sciences and ServicesRoyal Veterinary CollegeLondon NW10TUUK Therapie des maladies du muscle strie INSERM U974-CNRS UMR7215-UPMC UM76-Institut de Myologie Universite Pierre et Marie Curie-Universite Paris Descartes75000 ParisFrance Universite de Bourgogne Faculte des Sciences GabrielBio-PeroxIL21000 DijonFrance

The reduced diameter of skeletal myofibres is a hallmark of several congenital myopathies,yet the underlying cellular and molecular mechanisms remain *** this study,we investigate the role of HACD1/PTPLA,which is involved in the elongation of the very long chain fatty acids,in muscle fibre *** humans and dogs,HACD1 deficiency leads to a congenital myopathy with fibre size disproportion associated with a generalized *** of HACD1-deficient Labradors,Hacd1-knockout mice,and Hacd1-deficient myoblasts,we provide evidence that HACD1 promotes myoblast fusion during muscle development and *** further demonstrate that in normal differentiating myoblasts,expression of the catalytically active HACD1 isoform,which is encoded by a muscle-enriched splice variant,yields decreased lysophosphatidylcholine content,a potent inhibitor of myoblast fusion,and increased concentrations of≥C18 and monounsaturated fatty acids of *** lipid modifications correlate with a reduction in plasma membrane *** conclusion,we propose that fusion impairment constitutes a novel,non-exclusive pathological mechanism operating in congenital myopathies and reveal that HACD1 is a key regulator of a lipid-dependent muscle fibre growth mechanism.

关键词： centronuclear myopathy LPC MUFA PTPLA VLCFA

Long Term Survival after Resection of a Small Bowel Metastasis of Lung Adenocarcinoma: A Case Report

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Journal of Cancer Therapy 2011年第5期2卷 686-689页

作者： laurent Sulpice Emanuele D’Errico Alexis arnaud Michel Rayar Karim Boudjema Bernard Meunier 不详

Background: Small bowel metastases of lung adenocarcinoma represent a rare clinical entity, often diagnosed after complications due to obstruction, bleeding or bowel perforation. Case Report: We report a case of ileal metastasis discovered during an intestinal perforation. The patient was a 47-year-old man hospitalized in emergency for acute abdominal pain, with right lower quadrant abdominal defense and a clinical history of left lower pulmonary lobectomy for lung adenocarcinoma 6 months before. Exploratory laparotomy for peritonitis revealed a single ileal tumor which was resected with lymph nodes excision. Pathology finding revealed that it was compatible with an ileal metastasis of his lung adenocarcinoma. Conclusions: The suspicion of a small bowel metastasis of lung carcinoma, although rare, must be taken in consideration and to carry out an extensive surgery, because only this will have an improvement on the survival of these patients. The purpose of this investigation is to add a new case report to the few that exist in order to provide a therapeutic approach to these exceptional cases.

关键词： Ileal Metastasis Lung Cancer Metastasis Acute Abdominal Pain Lymph Nodes Excision

Utilisation of a Portable Electronic Nose, NeOse Pro, to Follow the Microbial Fermentation of a Yoghurt

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Food and Nutrition Sciences 2021年第1期12卷 90-105页

作者： Yann Demarigny Elodie Legrand Julia Sanchez arnaud Hallier Nathalie laurent Sami Slimani Thierry Livache Daniel Picque ISARA Lyon Equipe AgroLab BioDyMIA (Bioingénierie et Dynamique Microbienne aux Interfaces Alimentaires) ISARA Agrap&#244 le Lyon France Aryballe Technology Grenoble France INRA GMPA AgroParis Tech Paris France

Yoghurt is fermented milk which results from the exclusive action of Lactobacillus delbrueckii subsp bulgaricus and Streptococcus thermophilus. However, a disruption of the bacterial growth can lead to significant industrial losses. Currents monitoring methods, based on the checking of the pH during the fermentation step are not always satisfactory. The NeOse Pro system, a portable electronic nose, is a mean to obtain immediately aromatic profiles. In this work, we applied this technology to the yoghurt ecosystem, a highly hydrated product. The profiles obtained allowed us to discriminate yoghurts before and after fermentation. In detail, the discrepancy between the two bacteria cultured alone was slight. It was also the case when we compared different initial bacterial ratios. However, two different mixes of bacteria led to clearly distinguishable profiles. A GC/MS analysis performed on products fermented 7 h allowed us to explain the detection of acetaldehyde by the stimulation of some captors of the apparatus. NeOse Pro is so convenient to study the fermentation of yogurt.

关键词： NeOse Pro Yoghurt GC/MS Aroma

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选择合适北京鸭生长的地板系统

国外畜牧学（猪与禽） 2015年第7期35卷 43-45页

作者：夏俊花罗静如 laurent Bomard arnaud Moulac

饲养商品北京鸭是一项技能性工作。了解北京鸭的需要,包括选择合适的地板系统,这在世界各个地区均有不同的要求。稻草垫料和漏缝地板是最常用的地板系统。就孰优孰劣对这两个系统进行了比较。纵观商品北京鸭的饲养生产实践,显示世界各... 详细信息

饲养商品北京鸭是一项技能性工作。了解北京鸭的需要,包括选择合适的地板系统,这在世界各个地区均有不同的要求。稻草垫料和漏缝地板是最常用的地板系统。就孰优孰劣对这两个系统进行了比较。纵观商品北京鸭的饲养生产实践,显示世界各地主要使用两个不同的地板系统:垫料床系统或全漏缝板条地板系统。大多数情况下,北京鸭饲养在与健康要求相符合且各个国家可以应用的混凝土或结实粘土加垫料的饲养系统上。这种垫料可以是麦秸、

关键词：饲养生产饲养密度网上饲养栖架分群饲养现有法规饲养管理格里莫劳动力成本不锈钢材料

Third-order nonlinear optical susceptibility of crystalline oxide yttria-stabilized zirconia

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Photonics Research 2020年第2期8卷 110-120页

作者： GUILLAUME MARCAUD SAMUEL SERNA KARAMANIS PANAGHIOTIS CARLOS ALONSO-RAMOS XAVIER LE ROUX MATHIAS BERCIANO THOMAS MAROUTIAN GUILLAUME AGNUS PASCAL AUBERT arnaud JOLLIVET ALICIA RUIZ-CARIDAD LUDOVIC LARGEAU NATHALIE ISAC ERIC CASSAN SYLVIA MATZEN NICOLAS DUBREUIL MICHEL RERAT PHILIPPE LECOEUR laurent VIVIEN Centre de Nanosciences et Nanotechnologies(C2N) Université-Paris-SudCNRS UMR 9001Universite Paris-SaclayOrsay 91405France Department of Materials Science and Engineering Massachusetts Institute of TechnologyCambridgeMasschusetts 02139USA Department of Physics Bridgewater State UniversityBridgewaterMassachusetts 02325USA Institut des Sciences Analytiques et de Physico-Chimie pour l’Environnement et les Matériaux CNRSUniversite de Pau et des Pays de l’Adour64053 Pau CedexFrance Laboratoire Charles Fabry Institut d’Optique Graduate SchoolCNRSUniversitéParis-Saclay91127 Palaiseau CedexFrance LP2N Institut d’Optique Graduate SchoolCNRSUniv.Bordeaux33400 TalenceFrance

Nonlinear all-optical technology is an ultimate route for the next-generation ultrafast signal processing of optical communication *** nonlinear functionalities need to be implemented in photonics,and complex oxides are considered as promising candidates due to their wide panel of *** this context,yttria-stabilized zirconia(YSZ)stands out,thanks to its ability to be epitaxially grown on silicon,adapting the lattice for the crystalline oxide family of *** report,for the first time to the best of our knowledge,a detailed theoretical and experimental study about the third-order nonlinear susceptibility in crystalline *** self-phase modulation-induced broadening and considering the in-plane orientation of YSZ,we experimentally obtained an effective Kerr coefficient of n2YSZ=4.0±2×10^-19 m^2·W^-1 in an 8%(mole fraction)YSZ *** agreement with the theoretically predicted n2YSZ=1.3×10^-19 m^2·W^-1,the third-order nonlinear coefficient of YSZ is comparable with the one of silicon nitride,which is already being used in nonlinear *** promising results are a new step toward the implementation of functional oxides for nonlinear optical applications.

关键词： materials. nonlinear crystalline