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世界建筑 2005年第5期 82-83页

作者： apa czech_duli■ski_wróei apa切赫-杜林斯基-弗罗贝尔事务所

技术与管理中心(TMC)是运营克拉科夫-巴利采国际机场的综合服务大楼的一部分.就候机楼和货运楼而言,它在陆地和空中之间设置了明显的界限.TMC水平向的布局很好地结合了地势--从附近的公路上可以看到建筑的全景.总的来说,该建筑物由两部... 详细信息

技术与管理中心(TMC)是运营克拉科夫-巴利采国际机场的综合服务大楼的一部分.就候机楼和货运楼而言,它在陆地和空中之间设置了明显的界限.TMC水平向的布局很好地结合了地势--从附近的公路上可以看到建筑的全景.总的来说,该建筑物由两部分组成.一个是两层的行政管理和公众部分,位于通路附近,另一个是一系列横向的服务大厅和车库,其广场通向机场的停机坪.中间的'鼓形'建筑是人员和车辆的检查处.架在'鼓'之上的第3层的'横梁'包含了管理办公室,整座建筑就这样成为了通向机场的门户.

关键词：管理中心国际机场技术克拉波兰综合服务候机楼水平向

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学生公寓,克拉科夫,波兰

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世界建筑 2005年第5期 84-85页

作者： apa czech_duli■ski_wróbei apa切赫-杜林斯基-弗罗贝尔事务所

这个建筑试图协调着与街道垂直布置的建筑物与相邻建筑间的关系.横向的侧翼看起来像两座独立的建筑物;前面的一个过道被立面所遮盖而与街道相隔,第二个--从某种意义来讲--附属部分更伸向了地段的深处.建筑的北墙是砂岩抛光的面层,而东... 详细信息

这个建筑试图协调着与街道垂直布置的建筑物与相邻建筑间的关系.横向的侧翼看起来像两座独立的建筑物;前面的一个过道被立面所遮盖而与街道相隔,第二个--从某种意义来讲--附属部分更伸向了地段的深处.建筑的北墙是砂岩抛光的面层,而东西向则是被方形窗分割的简单的石膏面层--两个方向上的对比通过饰面材料的不同而加深.在北面墙壁后面有门厅,作为房间与交通噪音之间的隔离.也是由于交通噪音,房间里选用了小窗户.而实际上,这也体现了设计者的审美理念.白天,小窗户的金属抛光盖板闪闪发亮,晚上,透出灯光的小窗则在石墙表面布成了闪光的网.前立面根据主轴一分为二,这也清楚地表明了内部的布局结构.设计者在正门前放置的6根柱子,成为这个场所的标志.这一景象为我们带来了为其命名的灵感:柱子后面的建筑.

关键词：学生公寓克拉波兰相邻建筑建筑物街道布置过道

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美国

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作者：新加坡apa出版公司

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Effect of fexofenadine, a mast cell blocker, in infertile men with significantly increased testicular mast cells

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Asian Journal of Andrology 2002年第4期4卷 291-294页

作者： Selahittin ayan Duygu Dusmez apa Erdem Akbay Department of Urology Department of Pathology University of Mersin School of Medicine Mersin 33079 TurkeyDepartment of Urology

Aim: To investigate the role of fexofenadine, a mast cell blocker, on semen quality in the treatment of infertile men. Methods: The study included 16 Turkish idiopathic infertile men with azoospermia or oligozoospermia who underwent testicular biopsy to examine mast cells containing tryptase. In all patients, a complete medical history, clinical examination, semen analysis and serum hormone assay were carried out. The biopsy specimens were immunohistochemically stained with antihuman tryptase for mast cells. The number of total mast cells per seminiferous tubule was calculated and recorded as mast cell index. The patients were divided into two groups according to their mast cell index: the higher (≥1, n=9) and the lower (<1, n=7) index groups. Fexofenadine was administered orally at a dose of 180 mg/day for 4 to 9 months. Pre-and post-treatment semen parameters, including total motile sperm counts (TMC) were recorded and compared. Spontaneous pregnancies after the treatment were registered. Results: There was no statistically significant difference in TMC between the pre-treatment and post-treatment values in patients with higher and lower mast cell index (P≥0.05). In both groups, nobody had a significant response to the treatment and there was no spontaneous pregnancy after the treatment. Conclusion: Although testicular dysfunction is closely associated with increased number of testicular mast cells, fexofenadine, a mast cell blocker, appears not having any benefit in the treatment of Turkish infertile men with a significant increase in testicular mast cells. (Asian J Androl 2002 Dec; 4: 291-294)

关键词： male infertility testicular biopsy mast cells mast cell blocker fexofenadine semen quality

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Expression of sialyl Lewis^a relates to poor prognosis in cholangiocarcinoma

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World Journal of Gastroenterology 2005年第2期11卷 249-254页

作者： apa Juntavee Banchob Sripa Ake Pugkhem Narong Khuntikeo Sopit Wongkham Department of Biochemistry Faculty of Medicine and Liver Fluke and Cholangiocarcinoma Research CenterKhon Kaen UniversityKhon Kaen40002Thailand Department of Pathology Faculty of Medicine and Liver Fluke and Cholangiocarcinoma Research CenterKhon Kaen UniversityKhon Kaen40002Thailand Department of Surgery Faculty of Medicine and Liver Fluke and Cholangiocarcinoma Research Center Khon Kaen UniversityKhon Kaen40002Thailand Department of Biochemistry Faculty of Medicine and Liver Fluke and Cholangiocarcinoma Research Center Khon Kaen UniversityKhon Kaen40002Thailand

AIM: High levels of serum sialyl Lewisa (sLea) are frequently found in cholangiocarcinoma (CCA) patients and have been suggested to be a serum marker for CCA. However, the significance of this antigen in CCA is unknown. In this study, the clinical significance of sLea expression in CCA tissues and the possible role of sLea in vascular invasion in vitro were elucidated. METHODS: Expression of sLea in tumor tissues of 77 patients with mass-forming CCA and 33 with periductal infiltrating CCA was determined using immunohistochemistry. The in vitro assays on adhesion and transmigration of CCA cells to human umbilical vein endothelial cells were compared between CCA cell lines with and without sLea expression. RESULTS: sLea was aberrantly expressed in 60% of CCA tumor tissues. A significant relationship was found between the frequency of sLea expression and the mass-forming type CCA (P= 0.041), well differentiated histological grading (P=0.029), and vascular invasion (P=0.030). Patients with positive sLea expression had a significantly poorer prognosis (21.28 wk, 95% CI=16.75-25.81 wk) than those negative for sLea (37.30 wk, 95% CI=27.03-47.57 wk) (Pein more than KKU-100, the line without sLea expression (Peither sLea or E-selectin were added to the assays (P<0.001) CONCLUSION: This study demonstrates the clinical significance of sLea expression in vascular invasion, and an unfavorable outcome in CCA. The role of sLea in vascular invasion which may

关键词： Cholangiocarcinoma Sialyl Lewis Poor prognosis

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德国

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作者：新加坡apa出版公司

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Mediastinal tuberculous lymphadenitis presenting as an esophageal intramural tumor: A very rare but important cause for dysphagia

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World Journal of Gastroenterology 2007年第45期13卷 6104-6108页

作者： apa Pimenta JR Preto AMF Gouveia E Fonseca MML Pimenta Servio de CirurgiaGeral Porto Medical School and Hospital de So Joo PortoPortugal Institute of Molecular Pathology andImmunology of the University of Porto Porto Portugal Servio de CirurgiaGeral Porto Medical School and Hospital de So Joo PortoPortugal Pathology Department Porto Medical School andHospital de So Joo Porto Portugal Institute of Molecular Pathology andImmunology of the University of Porto Porto Portugal Radiology Department Porto Medical School andHospital de So Joo Porto Portugal

Dysphagia associated with esophageal mechanical obstruction is usually related to malignant esophageal diseases. Benign lesions are rarely a cause for this type of dysphagia, and usually occur either as an intramural tumor or as an extrinsic compression. Mediastinal tuberculous lymphadenitis is rare in adults, and even more rarely causes dysphagia. We report two cases of dysphagia in adult patients caused by mediastinal tuberculous lymphadenitis, presenting radiologicaUy and endoscopically as an esophageal submucosal tumor. Based on the clinical and imaging diagnosis, the patients underwent a right thoracotomy, and excision of the mass attached to and compressing the esophagus. Pathological examination of the specimens showed a chronic granulomatous inflammation with caseous necrosis, which was consistent with tuberculous lymphadenitis.

关键词： Dysphagia Tuberculous lymphadenitis Esophageal tumor Uncommon dysphagia Esophagealbenign lesion

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