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Coal fy ash:an emerging material for water remediation

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International Journal of Coal Science & Technology 2022年第3期9卷 18-49页

作者： N.B.Singh anupam agarwal Anindita De Pragya Singh Department of Chemistry and Biochemistry Sharda UniversityGreater NoidaIndia

Coal fy ash(CFA)is a byproduct of thermal power plant and collected from fue gases by *** of CFA depends on the type of coal used and it has both crystalline and amorphous *** is considered to be an environmental pollutant and used in number of *** is a useful material and widely used in cement production and as a promising adsorbent for water *** used for remediation of wastewater solves problems related to water quality issues and waste *** physical properties such as porosity,surface area,morphology,and chemical composition(iron oxide,alumina,silica,titania,etc.)make CFA efcient material for wastewater *** is also converted to geopolymer,which is used as an adsorbent and ***,organic compounds,toxic heavy metal ions,*** been removed using CFA and modifed CFA *** adsorption efciencies have been reported for diferent adsorbate and CFA *** of adsorption isotherm and kinetic models have been discussed.

关键词： Coal fy ash Adsorbent Dye Geopolymer Water remediation Pollutants

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减销售成本，但不减收入

经济管理文摘 2009年第10期 48-50页

作者： anupam agarwal Eric Harmon Michael Viertler

企业害怕对销售队伍动大手术是有道理的：这可是实现收入的发动机啊。不论对这架发动机做了多少修补工作，侗只要一想起来要对它进行大修，高管们就怕得要命。为了让销售工作能够进行下去，只要还能对付，企业就会继续零敲碎打地对其进... 详细信息

企业害怕对销售队伍动大手术是有道理的：这可是实现收入的发动机啊。不论对这架发动机做了多少修补工作，侗只要一想起来要对它进行大修，高管们就怕得要命。为了让销售工作能够进行下去，只要还能对付，企业就会继续零敲碎打地对其进行修修补补。

关键词：销售成本收入修补工作销售队伍销售工作发动机企业高管

EPASAD:ellipsoid decision boundary based Process-Aware Stealthy Attack Detector

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Cybersecurity 2024年第3期7卷 32-48页

作者： Vikas Maurya Rachit agarwal Saurabh Kumar Sandeep Shukla Department of Computer Science and Engineering Indian Institute of Technology KanpurkanpurIndia Merkle Science BangaloreIndia

Due to the importance of Critical Infrastructure(Cl)in a nation's economy,they have been lucrative targets for cyber *** critical infrastructures are usually Cyber-Physical Systems such as power grids,water,and sewage treatment facilities,oil and gas pipelines,*** recent times,these systems have suffered from cyber attacks numer-ous *** have been developing cyber security solutions for Cls to avoid lasting *** to standard frameworks,cyber security based on identification,protection,detection,response,and recovery are at the core of these *** of an ongoing attack that escapes standard protection such as firewall,anti-virus,and host/network intrusion detection has gained importance as such attacks eventually affect the physical dynamics of the ***,anomaly detection in physical dynamics proves an effective means to implement *** is one example of anomaly detection in the sensor/actuator data,representing such systems physical *** present EPASAD,which improves the detection technique used in PASAD to detect these micro-stealthy attacks,as our experiments show that PASAD's spherical boundary-based detection fails to *** method EPASAD overcomes this by using Ellipsoid boundaries,thereby tightening the boundaries in various dimen-sions,whereas a spherical boundary treats all dimensions *** validate EPASAD using the dataset produced by the TE-process simulator and the C-town *** results show that EPASAD improves PASAD's average recall by 5.8%and 9.5%for the two datasets,respectively.

关键词： Intrusion detection system Critical infrastructure security Industrial control system Machine learning

Reinforced tissue matrix to strengthen the abdominal wall following reversal of temporary ostomies or to treat incisional hernias

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World Journal of Gastrointestinal Surgery 2024年第3期16卷 823-832页

作者： Spencer P Lake Corey R Deeken Amit K agarwal Mechanical Engineering&Materials Science Washington University in St.LouisSt.LouisMO 63130United States Covalent Bio LLCSt.LouisMO 63025United States Department of Surgery McGovern Medical School at UTHealthHoustonTX 77026United States

BACKGROUND Abdominal wall deficiencies or weakness are a common complication of tem-porary ostomies,and incisional hernias frequently develop after colostomy or ileostomy *** use of synthetic meshes to reinforce the abdominal wall has reduced hernia *** meshes have also been used to enhance healing,particularly in contaminated *** tissue matrices(R-TMs),which include a biologic scaffold of native extracellular matrix and a syn-thetic component for added strength/durability,are designed to take advantage of aspects of both synthetic and biologic *** date,RTMs have not been reported to reinforce the abdominal wall following stoma *** Twenty-eight patients were selected with a parastomal and/or incisional hernia who had received a temporary ileostomy or colostomy for fecal diversion after rectal cancer treatment or *** hernia repair and proximal stoma closure,RTM(OviTex®1S permanent or OviTex®LPR)was placed to reinforce the abdominal wall using a laparoscopic,robotic,or open surgical ***-operative follow-up was performed at 1 month and 1 *** recurrence was determined by physical examination and,when necessary,via computed tomo-graphy *** endpoints included length of hospital stay,time to return to work,and hospital *** complications of the wound/repair site included presence of surgical site infection,seroma,hematoma,wound dehiscence,or fistula *** The observational study cohort included 16 male and 12 female patients with average age of 58.5 years±16.3 years and average body mass index of 26.2 kg/m^(2)±4.1 kg/m^(2).Patients presented with a parastomal hernia(75.0%),in-cisional hernia(14.3%),or combined parastomal/incisional hernia(10.7%).Using a laparoscopic(53.6%),robotic(35.7%),or open(10.7%)technique,RTMs(OviTex®LPR:82.1%,OviTex®1S:17.9%)were placed using sublay(82.1%)or intraperitoneal onlay(IPOM;17.9%)mesh *** 1-mo

关键词： Reinforced tissue matrix Reinforced forestomach matrix Ileostomy Colostomy Ostomy takedown Incisional hernia Abdominal wall

Transcranial direct current stimulation as early augmentation in adolescent obsessive compulsive disorder:A pilot proof-of-concept randomized control trial

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World Journal of Clinical Pediatrics 2024年第2期13卷 161-170页

作者： Aditya Agrawal Vivek agarwal Sujita Kumar Kar Amit Arya Department of Psychiatry King George Medical UniversityUttar PradeshLucknow 226003India

BACKGROUND Transcranial direct current stimulation(tDCS)is proven to be safe in treating various neurological conditions in children and *** is also an effective method in the treatment of OCD in *** To assess the safety and efficacy of tDCS as an add-on therapy in drug-naive adolescents with *** We studied drug-naïve adolescents with OCD,using a Children’s Yale-Brown obsessive-compulsive scale(CY-BOCS)scale to assess their *** active and sham groups were given fluoxetine,and we applied cathode and anode over the supplementary motor area and deltoid for 20 min in 10 *** occurred at 2,6,and 12 wk using *** Eighteen adolescents completed the study(10-active,8-sham group).CY-BOCS scores from baseline to 12 wk reduced significantly in both groups but change at baseline to 2 wk was significant in the active group *** mean change at 2 wk was more in the active group(11.8±7.77 vs 5.25±2.22,P=0.056).Adverse effects between the groups were *** tDCS is safe and well tolerated for the treatment of OCD in ***,there is a need for further studies with a larger sample population to confirm the effectiveness of tDCS as early augmentation in OCD in this population.

关键词： Adolescents Early augmentation Obsessive compulsive disorder Safety Transcranial direct current stimulation

Identifying the stability of housekeeping genes to be used for the quantitative real-time PCR normalization in retinal tissue of streptozotocin-induced diabetic rats

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 794-805页

作者： Muhammad Zulfiqah Sadikan Nurul Alimah Abdul Nasir Mohammad Johari Ibahim Igor Iezhitsa Renu agarwal Department of Pharmacology Faculty of MedicineManipal University College Malaysia(MUCM)Bukit BaruMelaka 75150Malaysia Centre for Neuroscience Research(NeuRon) Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Medical Education Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Biochemistry and Molecular Medicine Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia School of Medicine International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia Department of Pharmacology and Bioinformatics Volgograd State Medical UniversityVolgograd 400131Russia

AIM:To investigate the stability of the seven housekeeping genes:beta-actin(ActB),glyceraldehyde-3-phosphate dehydrogenase(GAPDH),18s ribosomal unit 5(18s),cyclophilin A(CycA),hypoxanthine-guanine phosphoribosyl transferase(HPRT),ribosomal protein large P0(36B4)and terminal uridylyl transferase 1(U6)in the diabetic retinal tissue of rat ***:The expression of these seven genes in rat retinal tissues was determined using real-time quantitative reverse transcription polymerase chain reaction(RT-qPCR)in two groups;normal control rats and streptozotocininduced diabetic *** stability analysis of gene expression was investigated using geNorm,NormFinder,BestKeeper,and comparative delta-Ct(ΔCt)***:The 36B4 gene was stably expressed in the retinal tissues of normal control animals;however,it was less stable in diabetic *** 18s gene was expressed consistently in both normal control and diabetic rats’retinal *** this gene was the best reference for data normalisation in RT-qPCR studies that used the retinal tissue of streptozotocin-induced diabetic ***,there was no ideal gene stably expressed for use in all experimental ***:Identifying relevant genes is a need for achieving RT-qPCR validity and reliability and must be appropriately achieved based on a specific experimental setting.

关键词： housekeeping genes stability real-time reverse transcription polymerase chain reaction retinal tissue streptozotocin-induced diabetic rats

Effect of inlet elbow on rotation stall in waterjet ppropulsionpump

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Fundamental Research 2024年第4期4卷 898-906页

作者： Wei Li Shuo Li Leilei Ji Enda Li Weidong Shi Ramesh agarwal Muhammad Awais National Research Center of Pumps Jiangsu UniversityZhenjiang 212013China Institute of Fluid Engineering Equipment Technology Jiangsu UniversityZhenjiang 212009China College of Mechanical Engineering Nantong UniversityNantong 226019China departmentof Mechanical Engineering&Materials Science Washington University in StLouisSt.LouisMO6330US.

To study the influence of an elbow inlet on the rotating stall characteristics of a waterjet propulsion pump(WJPP),a three-dimensional internal flow field in a WJPP under a straight-pipe inlet and elbow inlet is numerically *** comparing the hydraulic performance of WJPP under the two inlet conditions,the internal relationship between the inlet mode and the flow pattern in the pump is *** on unsteady pressure fluctuation characteristics and wavelet analysis,the influence of the inlet mode on the rotating stall is revealed,and the stall transient propagation characteristics under critical stall conditions are *** disturbance effects of the inlet channel geometry disappear under low flow rate conditions,the main disturbance is induced by the highspeed countercurrent,and the flow pattern under the elbow inlet is better than that under the straight-pipe *** the straight-pipe inlet,the single-stall nucleus in the WJPP temporarily experiences a low-frequency and high-amplitude disturbance,which subsequently transforms into a mode of multi-stall nuclei with high-frequency circumferential *** the elbow inlet,the rotating stall always maintains a mode of high-amplitude and low-frequency disturbance,which represents the transient characteristics of a single stall core propagating in the circumferential direction inside the *** results of this study have a reference value for structural design optimization in a WJPP.

关键词： Waterjet propulsion pump Inlet condition Rotation stall Flow structure Pressurefluctuation

Advancements in nanotechnology for the delivery of phytochemicals

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Journal of Integrative Medicine 2024年第4期22卷 385-398页

作者： Divya Chauhan Pavan K.Yadav Nazneen Sultana Arun agarwal Saurabh Verma Manish K.Chourasia Jiaur R.Gayen Division of Pharmaceutics and Pharmacokinetics Central Drug Research InstituteCouncil of Scientific and Industrial ResearchLucknow 226031Uttar PradeshIndia Academy of Scientific and Innovative Research Ghaziabad 201002Uttar PradeshIndia

Phytosomes(phytophospholipid complex) are dosage forms that have recently been introduced to increase the stability and therapeutic effect of herbal medicine. Currently, bioactive herbs and the phytochemicals they contain are considered to be the best remedies for chronic diseases. One promising approach to increase the efficacy of plant-based therapies is to improve the stability and bioavailability of their bio-active ingredients. Phytosomes employ phospholipids as their active ingredients, and use their amphiphilic properties to solubilize and protect herbal extracts. The unique properties of phospholipids in drug delivery and their use in herbal medicines to improve bioavailability results in significantly enhanced health benefits. The introduction of phytosome nanotechnology can alter and revolutionize the current state of drug delivery. The goal of this review is to explain the application of phytosomes, their future prospects in drug delivery, and their advantages over conventional formulations.

关键词： Phytochemical Bioavailability Drug delivery system Phytosome Plant extracts

Clinical profile and outcomes of hepatocellular carcinoma in primary Budd-Chiari syndrome

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 699-715页

作者： Ankit agarwal Sagnik Biswas Shekhar Swaroop Arnav Aggarwal Ayush agarwal Gautam Jain Anshuman Elhence Arun Vaidya Amit Gupte Ravi Mohanka Ramesh Kumar Ashwani Kumar Mishra Shivanand Gamanagatti Shashi Bala Paul Subrat Kumar Acharya Akash Shukla Shalimar Department of Gastroenterology and Human Nutrition All India Institute of Medical SciencesNew Delhi 110029DelhiIndia Department of Gastroenterology Seth Gordhandas Sunderdas Medical College and KEM HospitalMumbai 400012MaharashtraIndia Department of Gastroenterology Sir HN Reliance Foundation HospitalMumbai 400004India Department of Liver Transplant and HPB Sir HN Reliance Foundation HospitalMumbai 400004India Department of Gastroenterology All India Institute of Medical SciencesPatna 801507India Professor of Biostatistics National Drug Dependence Treatment Centre(NDDTC)All India Institute of Medical SciencesNew Delhi 110029India Department of Radiodiagnosis All India Institute of Medical SciencesNew Delhi 110029DelhiIndia

BACKGROUND There is scant literature on hepatocellular carcinoma(HCC)in patients with Budd-Chiari syndrome(BCS).AIM To assess the magnitude,clinical characteristics,feasibility,and outcomes of treatment in *** A total of 904 BCS patients from New Delhi,India and 1140 from Mumbai,India were *** prevalence and incidence of HCC were determined,and among patients with BCS-HCC,the viability and outcomes of interventional therapy were *** In the New Delhi cohort of 35 BCS-HCC patients,18 had HCC at index presentation(prevalence 1.99%),and 17 developed HCC over a follow-up of 4601 person-years,[incidence 0.36(0.22-0.57)per 100 person-years].BCS-HCC patients were older when compared to patients with BCS alone(P=0.001)and had a higher proportion of inferior vena cava block,cirrhosis,and long-segment vascular *** median alpha-fetoprotein level was higher in patients with BCS-HCC at first presentation than those who developed HCC at follow-up(13029 ng/mL vs 500 ng/mL,P=0.01).Of the 35 BCS-HCC,26(74.3%)underwent radiological interventions for BCS,and 22(62.8%)patients underwent treatment for HCC[transarterial chemoembolization in 18(81.8%),oral tyrosine kinase inhibitor in 3(13.6%),and transarterial radioembolization in 1(4.5%)].The median survival among patients who underwent interventions for HCC compared with those who did not was 3.5 years vs 3.1 mo(P=0.0001).In contrast to the New Delhi cohort,the Mumbai cohort of BCS-HCC patients were predominantly males,presented with a more advanced HCC[Barcelona Clinic Liver Cancer C and D],and 2 patients underwent liver *** HCC is not uncommon in patients with *** interventions and liver transplantation are feasible in select primary BCS-HCC patients and may improve outcomes.

关键词： Budd chiari syndrome Cancer Cirrhosis Thrombosis Liver Varices Transarterial chemoembolization Hepatic venous outflow tract obstruction