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Electrocortical Activity Differences Related to Saccadic Movements between Bipolar Patients and Healthy Subjects

Neuroscience & Medicine 2013年第2期4卷 63-70页

作者： Washington Adolfo Batista Juliana Bittencourt Jose Inácio Salles Silmar Teixeira Luis F.Basile antonio egidio nardi Claudia Diniz Fernanda Novis Luciana Angélica Silveira Rafael de Assis da Silva Amanda de Lima Teixeira Elie Cheniaux Flávio Kapczinki Mauricio Cagy Roberto Piedade Bruna Velasques Pedro Ribeiro Brain Mapping and Sensory Motor Integration Institute of Psychiatry of the Federal University of Rio de Janeiro(IPUB/UFRJ)Rio de JaneiroBrazil Neurophysiology and Neuropsychology of Attention Institute of Psychiatry of the Federal University of Rio de Janeiro(IPUB/UFRJ)Rio de JaneiroBrazil Institute of Applied Neuroscience(INA) Rio de JaneiroBrazil School of Physical Education Bioscience Department(EEFD/UFRJ)Rio de JaneiroBrazil Federal Confederation of Volleyball Rio de JaneiroBrazil Veiga de Almeida University Rio de JaneiroBrazil Division of Neurosurgery University of Sao Paulo Medical SchoolSao PauloBrazil Laboratory of Psychophysiology Department of Psychology and PhonoaudiologyUMESPSao PauloBrazil Panic&Respiration Laboratory Institute of PsychiatryFederal University of Rio de JaneiroRio de JaneiroBrazil National Institute of Translational Medicine(INCT-TM) Brazil Anxiety&Depression Laboratory Institute of Psychiatry of Federal University of Rio de Janeiro(IPUB/UFRJ)Rio de JaneiroBrazil Department of Medical Specialities State University of Rio de Janeiro(UERJ)Rio de JaneiroBrazil Laboratory of Molecular Psychiatry Bipolar Disorders Program and INCT Translational MedicineHospital de Clínicas de Porto AlegreUniversidade Federal do Rio Grande do SulPorto AlegreBrazil Biomedical Engineering Program Universidade Federal do Rio de JaneiroRio de JaneiroBrazil Neuromuscular Research Laboratory National Institute of Traumatology and Orthopedics(NITO)Rio de JaneiroBrazil

Objective: The present study aimed to investigate and to compare the electrophysiological changes in bipolar patients and healthy subjects during the execution of a saccade task. Materials and Methods: The subjects had to respond to a fixed visual stimulus presented by a LEDs bar. We executed an ANOVA (one-way) and post hoc Scheffé test to examine the difference of absolute alpha power and reaction time among four groups: control, depression, manic and euthymic. We observed the frontal, parietal and occipital regions. The paired t test was realized on each electrode and group to compare the pre and post moment in the task. Results: We observed a statistical difference among the groups for the behavioral variable—saccade reaction time. For the electrophysiological variable—absolute alpha power, we did not find significant difference between the moments (pre and post stimulus presentation) for none of the electrodes of each bipolar group. However, the results pointed out to a difference between the moments for F3, P3, O1 and O2 electrodes for control group. Conclusion: We cannot affirm that the task influences the cortical activity of the patients. It is possible that the method used to analyze the data is not the adequate. The time-frequency analysis could be better to analyze the present data. We also observed that the absolute alpha power could be considered a marker of bipolar disorder, but not of the different states (i.e., mania, depression, euthymia).

关键词： Sensorimotor Integration Saccadic Movement Attention Bipolar Disease and Electroencephalography

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Carbon concentrations and carbon storage capacity of three old-growth forests in the Sila National Park,Southern Italy

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Journal of Forestry Research 2023年第1期34卷 233-242页

作者： Giovanni Di Matteo Giuseppe Luzzi antonio Basile Angelo Sposato Giada Bertini Ulderico Neri Bruno Pennelli Rosario Napoli Pierfrancesco nardi Consiglio per la ricerca e l’analisi dell’economia agraria Research Centre for Agriculture and Environment(CREA-AA)Via della Navicella 2-400184 RomeItaly Sila National Park Via NazionaleLorica Di San Giovanni in Fiore87055 CosenzaItaly Consiglio per la ricerca e l’analisi dell’economia agraria Research Centre for Forestry and Wood(CREA-FL)Viale Santa Margherita 8052100 ArezzoItaly

Old-growth forests play a key-role in reducing atmospheric carbon dioxide(CO_(2)) concentrations by storing large CO_(2)amounts in biomass and soil over *** quantifies the carbon pool into different forest compartments in three Mediterranean old-growth forests of Southern Italy populated by Pinus laricio,Fagus sylvatica and Abies *** carbon pools have been assessed per compartment,i.e.,living trees,dead wood,litterfall(foliar and woody),roots and 0-20 cm topsoil,combining the whole old-growth forest mass,(i.e.,using tree allometric relationships,deadwood factor conversions,root-to-shoot ratios,litterfall and soil samplings) by the respective organic carbon *** results show the considerable capacity of these forest ecosystems in storing CO_(2)in biomass and soil,with carbon pool values ranging from 532.2to 596.5 Mg C *** trees and 0-20 cm topsoil had larger carbon pool,contributing 53.0 and 22.1%,*** most cases,organic carbon concentration was higher(more than 60%) than the average carbon conversion rate of 50%,especially in living trees,deadwood,and woody *** study contributes further scientific evidence of the capacity of old-growth forests in storing CO_(2)in their different compartments,with special evidence on tree biomass,litterfall and mineral soil,thereby highlighting the key role of old-growth forests within the challenge of climate change mitigation.

关键词： Ecosystem carbon pool Organic carbon concentration Ecosystem compartment Climate change mitigation Carbon forestry

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Integrating VGI and 2D hydraulic models into a data assimilation framework for real time flood forecasting and mapping

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Geo-Spatial Information Science 2019年第4期22卷 223-236,I0001页

作者： antonio Annis Fernando nardi Water Resources Research and Documentation Centre(WARREDOC) University for Foreigners of PerugiaPerugiaItaly Department of Civil and Environmental Engineering(DICEA) University of FlorenceFlorenceItaly Institute of Water and Environment(InWE) Florida International UniversityMiamiFLUSA

Crowdsourced data can effectively observe environmental and urban ecosystem *** use of data produced by untrained people into flood forecasting models may effectively allow Early Warning Systems(EWS)to better perform while support decision-making to reduce the fatalities and economic losses due to inundation *** this work,we develop a Data Assimilation(DA)method integrating Volunteered Geographic Information(VGI)and a 2D hydraulic model and we test its *** proposed framework seeks to extend the capabilities and performances of standard DA works,based on the use of traditional in situ sensors,by assimilating VGI while managing and taking into account the uncertainties related to the quality,and the location and timing of the entire set of observational *** November 2012 flood in the Italian Tiber River basin was selected as the case *** show improvements of the model in terms of uncertainty with a significant persistence of the model updating after the integration of the VGI,even in the case of use of few-selected observations gathered from social *** will encourage further research in the use of VGI for EWS considering the exponential increase of quality and quantity of smartphone and social media user worldwide.

关键词： Crowdsourced data VGI data assimilation(DA) flood forecasting 2D hydraulic modelling

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Effect of genetic factors on the association between coronary artery disease and PTPN22 polymorphism

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World Journal of Cardiology 2014年第6期6卷 376-380页

作者： Fulvia Gloria-Bottini Patrizia Saccucci Maria Banci Paolo nardi Mattia Scognamiglio antonio Pellegrino egidio Bottini Luigi Chiariello Department of Biomedicine and Prevention School of MedicineUniversity of Rome Tor Vergata00133 RomeItaly Department of Cardiology Valmontone Hospital Department of Cardiac Surgery University of Rome Tor VergataSchool of Medicine

PTPN22 has been previously found associated with coronary artery disease(CAD). In the present note we have studied the effect of p53 codon 72,acid phosphatse locus 1(ACP1) and adenosine deaminase(ADA) genetic polymorphism on the strength of association between PTPN22 and CAD. We have studied 133 non diabetic subjects with CAD,122 non diabetic cardiovascular patients without CAD and 269 healthy blood donors. Informed written consent was obtained from all subjects and the study was approved by the Ethical Committee. A high significant association between PTPN22 and CAD is observed in carriers of *A allele of ACP1 with a higher proportion of *T allele carriers in non diabetic subjects with CAD as compared to controls and to non diabetic subjects with cardiovascular diseasewithout CAD. A similar pattern is observed in carriers of *Pro allele of p53 codon 72 with a higher proportion of *T allele carriers in non diabetic subjects with CAD as compared to other groups. A highly significant association between PTPN22 and CAD is observed in carriers of ADA2 *2 allele with higher proportion of *T allele carriers in non diabetic subjects with CAD as compared to other group. There is a high significant correlation between the number of factors that contributes to increase the strength of association between PTPN22 *T and CAD and the proportion of *T carriers in CAD. ACP1,p53 codon 72 and ADA are involved in immune reaction and give an important additive contribution to the strength of association between PTPN22 and CAD. This study stresses the importance of the simultaneous analysis of multiple genes functionally related to a specific disease: the approach may give important hints to understand multifactorial disorders.

关键词：冠的动脉疾病 PTPN22 酸 phosphatse 地点 1 腺苷脱氨基酶 2 p53 codon 72

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意大利地中海隼(Falco biarmicus feldeggii)繁殖种群的景观尺度空间分布

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AMBIO－人类环境杂志 2008年第6期37卷 422-426页

作者： Alessandro Andreotti Giovanni Leonardi Maurizio Sarà Massimo Brunelli Lorenzo De Lisio Augusto De Sanctis Mauro Magrini Riccardo nardi Paolo Perna antonio Sigismondi 梁虹意大利野生动物研究所(INFS) 锡耶纳大学巴勒莫大学 Romana鸟类观察与保护站(S.R.O.P.U.) 意大利卡美日诺大学阿普利亚区公园办公室

地中海隼(Falco biarmicus feldeggii)是欧洲濒危程度最高的物种之一。其全球数量估计不超过几百对,不均匀分布于西西里至里海的广阔而片断化的地区。最近统计表明,西西里地中海隼在全部种群数量中占很大比例(>25%)。因此,意大利政府提... 详细信息

地中海隼(Falco biarmicus feldeggii)是欧洲濒危程度最高的物种之一。其全球数量估计不超过几百对,不均匀分布于西西里至里海的广阔而片断化的地区。最近统计表明,西西里地中海隼在全部种群数量中占很大比例(>25%)。因此,意大利政府提出一项国家行动计划。在这一计划框架下,我们在意大利进行了首次地中海隼种群数量的全国调查(2003～2004年)。本研究的地理范围包括地中海隼的整个繁殖区,即西西里和意大利半岛(n=2909栅格单元,10km×10km)。另外,我们尽量考虑了以往(1993～2001年)区域调查的结果。我们对各个繁殖亚群的大小和分布进行评估,鉴别在景观尺度上与巢址空间分布相关的主要环境特征。在184个栅格单元(全部栅格地图的6.4%)中发现有地中海隼的存在,但同一繁殖期内地中海隼数量估计不超过140～172对(其中70～80对分布于西西里)。大陆繁殖栅格的隔离程度较高,而西西里地区的单元更为密集。海拔高度是意大利单元聚集性的主要影响因素;另外气候、降水量和植被等环境因素对此也有重要影响。本研究表明保护区内的处于繁殖期的地中海隼数量较少(23%～28%),意大利政府的保护措施还不够完善。在适于地中海隼巢址不规则空间聚集的优先性生境保护方面,多个小型、分散分布的特定保育区(SAC)优于大型特定保护区(SPA)。

关键词：繁殖种群空间分布景观尺度地中海意大利种群数量不均匀分布地理范围

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