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Evaluation of Larval Development of Dirofilaria immitis in Different Populations of Aedes aegypti and Aedes albopictus

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Open Journal of Veterinary Medicine 2013年第6期3卷 277-281页

作者： Gílcia Aparecida de Carvalho Rafael Trindade Maia Rafael antonio Nascimento ramos carlos Fernando Salgueirosa de Andrade Maria Aparecida da Gloria Faustino Leucio Camara Alves Unidade Acadêmica de Garanhuns Universidade Federal Rural de Pernambuco Garanhuns Brazil

Dirofilaria immitis is an important nematode parasite commonly known as heartworm. This filarioid is transmitted by culicid vectors and primarily affects dogs, but other animals may also become infected, such as wild carnivores, cats and humans. The aim of the present study was to assess the development of D. immitis larvae in different culicid populations under laboratory conditions. Adult females of populations of Aedes aegypti from the city of Recife (P1), the city of Campinas (P2) and the Rockefeller strain from the Centers for Disease Control (P3) and one population of Aedes albopictus from Recife (P4) were fed for two hours with infected dog blood containing 2,000 microfilariae/ml of D. immitis. After artificial feeding, the specimens were maintained under controlled conditions. Ten females from each population were dissected daily over 14 days. The infection ratio and vector efficiency index were calculated and D. immitis development from L1 to L3 was assessed. The larvae in P1, P2, P3 and P4 reached the third stage in 11, 10, 14 and 9 days, respectively. The vector efficiency index was 53.8%, 20.0%, 7.4% and 25.2% in P1, P2, P3 and P4, respectively. The findings demonstrate that D. immitis larvae develop in all culicid populations studied herein. Based on mosquito mortality, development time and VEI the A. albopictus population from Recife (P4) demonstrated the best performance as vector. This is the second report of D. immitis development in A. albopictus from Brazil. The present data reinforce the role of this species as vector of D. immitis in an area where greater importance has long been given to A. aegypti.

关键词： Culicid Vector Heartworm Dog Experimental Infection

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Association between Frailty Syndrome and Anemia in Community-Dwelling Elderly

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Advances in Aging Research 2019年第5期8卷 75-87页

作者： Elisa Priscila Sousa de Assis Barbara Gazolla de Macêdo Thais Almeida Marques da Silva Poliana de Paula Dias Rezende érica Leandro Marciano vieira antonio Lucio Teixeira Junior carlos Maurício de Figueiredo Antunes Laboratório de Epidemiologia Programa de Pós-gradua&#231 o Stricto Sensu em Medicina e Biomedicina Instituto de Ensino e Pesquisa da Santa Casa de Belo Horizonte Belo Horizonte Brasil Fundaç o Hospitalar do Estado de Minas Gerais (FHEMIG) Hospital Regional de Barbacena Fisioterapia Respiratória Barbacena Brasil Departamento de Fisioterapia Instituto da Previdência dos Servidores do Estado de Minas Gerais (IPSEMG) Belo Horizonte Brasil Laboratório Interdisciplinar de Investigaç o Médica Faculdade de Medicina Universidade Federal de Minas Gerais (UFMG) Belo Horizonte Brasil Centre of Addiction and Mental Health (CAMH) Toronto Canada

Frailty is an important and complex phenomenon in the fields of geriatrics and gerontology and a highly relevant topic. Frailty syndrome (FS) is a multidimensional clinical condition characterized by loss of physiological and cognitive reserves across multiple organ systems. The Fried frailty phenotype is the main model used to categorize FS. Recent studies have shown an association between anemia, low hemoglobin concentration and frailty. This study aimed to assess the association between FS and anemia in community-dwelling elderly. An observational cross-sectional design was used, with 308 elderly subjects. Most participants were women (78.2%) between 60 and 69 years old (50.6%). The average schooling level was 9.7 years. Anemia was detected in 9.7% of participants. The frequency of frailty, pre-frailty and non-frailty was 8.2, 74.0 and 17.8%, respectively. The multivariate ordinal logistic regression model identified low levels of brain-derived neurotrophic factor (BDNF) (OR = 0.9, 95% CI = 0.9;0.9) as risk factor associated with FS. No significant association was found between frailty and anemia. Moreover, FS may be influenced by low schooling levels, despite the non-significant result obtained in the statistical model. These findings contribute to elucidating other factors associated with FS, especially in community-dwelling elderly.

关键词： Anemia Frailty Elderly

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Pancreatic paracoccidioidomycosis simulating malignant neoplasia:Case report

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World Journal of Gastroenterology 2013年第34期19卷 5750-5753页

作者： Talles Bazeia Lima Maria Aparecida Custódio Domingues carlos antonio Caramori Giovanni Faria Silva Cássio vieira de Oliveira Fábio da Silva Yamashiro Letícia de Campos Franzoni Lígia Yukie Sassaki Fernando Gomes Romeiro Division of Gastroenterology Department of Internal MedicineBotucatu School of MedicineRubio JuniorDistrict S/N18618-970 So PauloBrazil Department of Pathology Botucatu School of MedicineRubio Junior District S/N18618-970 So PauloBrazil

Paracoccidioidomycosis is a systemic granulomatous disease caused by fungus,and must be considered in the differential diagnosis of intra-abdominal tumors in endemic *** report a rare case of paracoccidioidomycosis in the pancreas.A 45-year-old man was referred to our institution with a 2-mo history of epigastric abdominal pain that was not diet-related,with night sweating,inappetence,weight loss,jaundice,pruritus,choluria,and acholic feces,without signs of sepsis or palpable *** ultrasonography(US)showed a solid mass of approximately 7 cm×5.5 cm on the pancreas *** computerized tomography showed dilation of the biliary tract,an enlarged pancreas(up to 4.5 in the head region),with dilation of the major pancreatic *** patient underwent exploratory laparotomy,and the surgical description consisted of a tumor,measuring 7 to 8 cm with a poorly-defined margin,adhering to posterior planes and mesenteric vessels,showing an enlarged bile *** drainage of the biliary tract,Rouxen-Y gastroenteroanastomosis,lymph node excision,and biopsies were performed,but malignant neoplasia was not *** analysis showed chronic pancreatitis and a granulomatous chronic inflammatory process in the choledochal lymph ***-alcohol resistant bacillus and fungus screening were ***-needle aspiration of the pancreas was performed under US *** smear was compatible with infection by Paracoccidioides *** report a rare case of paracoccidioidomycosis simulating a malignant neoplasia in the pancreas head.

关键词： Paracoccidioidomycosis Pancreas Fungus infection Pancreatic tumors Differential diagnosis

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Mine tailings storage dams modify upstream headwater fish assemblages

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Water Biology and Security 2023年第2期2卷 32-42页

作者： Gilberto N.Salvador Robert M.Hughes Fabio vieira Raphael Ligeiro Luciano F.A.Montag Ecology and Conservation Laboratory(LABECO) Federal University of ParaBiological Sciences InstituteRua Augusto Correa01GuamaCaixaBelemPA479Brazil Fish Ecology and Conservation Laboratory(Eco-Peixes) Federal University of Minas GeraisBiological Sciences InstituteAv.Antonio Carlos6627Belo HorizonteMGCEP:31.270-901Brazil Amnis Opes Institute 2895 SE GlennCorvallisOR97333USA Department of Fisheries Wildlife&Conservation SciencesOregon State UniversityCorvallisOR97331USA Zoology Department Federal University of Minas GeraisBiological Sciences InstituteAv.Antonio Carlos6627CEP:31.270-901Belo HorizonteMGBrazil

Riverscape connectivity is a critically important component determining the ecological condition of lotic *** evaluated changes in fish assemblages caused by the loss of connectivity by mine tailings storage dams(TSDs),hypothesizing that headwater fish assemblages are restructured by TSDs located downstream,even though the upstream habitats are not *** used standard methods to collect fish in 24 first to third order sites,with half draining to TSDs(dammed)and the other half free from this impact(undammed).To identify differences between treatments,we used PERMANOVA to test both environmental variables and ichthyofauna composition(Bray-Curtis similarity index)and evaluated the biological metrics that most influenced assemblage composition *** expected,we observed no difference between treatments for environmental variables,but we did observe differences in fish assemblage *** also observed five metrics with lower values in dammed streams(richness and abundance of intolerant species,siluriform richness,and abundance of Pareiorhaphis *** and Trichomycterus brasiliensis)and two metrics with higher values in dammed streams(perciform richness and abundance of Oligosarcus argenteus).We believe these changes resulted from of stream fragmentation by TSDs,in addition to source-sink mechanisms and conclude that mine TSDs located downstream change headwater fish assemblages,an impact often neglected in biomonitoring and bioassessment studies.

关键词： Habitat fragmentation Source-sink dynamics Iron ore mining Rio Doce basin

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Safety and Efficacy of PTCTS Cosmetic Gel: Study on Human Radiodermatitis Lesions

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Case Reports in Clinical Medicine 2015年第10期4卷 327-333页

作者： Silvia Regina Graziani Brigitte M. Van Eyll carlos Elias Fristachi Maria de Lourdes Higuchi Renata Ikegami Jose antonio Ramires Arnaldo vieira de Carvalho Cancer Institute Sao Paulo Brazil Heart Institute (InCor) of Clinical Hospital Medical School University of S&atildeo Paulo S&atildeo Paulo Brazil

Radiodermatitis is a constant complication after radiotherapy with no efficient drug for prevention and treatment. Its physiopathology is complex, possibly related to injury of epidermis and endothelial cells from the basal layer by radiolysis, overproduction of free radicals, pro-inflammatory cytokines, and inflammation. PTCTS gel is an after sun cosmetic gel composed by anti-oxidative plant extract rich in natural nanoparticles and thermal water (Complex A) and recombinant protein of Trypanosoma cruzi transialidase (Complex B), with high anti-oxidative and anti-apoptotic effects, presenting anti-aging and healing cutaneous properties. Objective: To study the safety and efficacy of PTCTS gel for topic use in volunteer subjects with healthy skin, and in patients with radiodermatitis, in different concentrations of Complexes A and B. Material and Methods: The project was approved by the Ethical Committee of Arnaldo vieira de Carvalho Institute, Sao Paulo, Brazil. The individuals were submitted to laboratorial toxicity study through tests for liver and kidney function, levels of blood glucose and blood count before and after 7 days of PTCTS application. We studied two groups: GI-22 volunteers with healthy skin, presenting articular or skeletal muscle pain and GII-38 patients in radiotherapy for breast or head and neck cancer, with radiodermatitis grade 2 or 3. The patients were evaluated before and after 1.0 ml/cm2 PTCTS gel application, twice a day. We tested Complex B in four different concentrations, and Complex A concentrations varied inversely. Results: No irritation signs were observed in GI nor GII group, 64% of GI had important decrease in the intensity of the muscular or articular pain, and 99% of GII showed regression of radiodermatitis, all exhibiting relief of pain. No patient presented hematologic, renal or hepatic toxicity. Conclusion: PTCTS cosmetic gel is a safe option for radiodermatitis treatment, with no side effects or laboratorial toxicity in diff

关键词： Radiodermatitis Nanoparticles Thermal Water Transialidase Toxicity PTCTS Cosmetic Gel

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Interleukin 28B-related polymorphisms: A pathway for understanding hepatitis C virus infection?

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World Journal of Gastroenterology 2013年第42期19卷 7399-7404页

作者： Raquel Francine Liermann Garcia Simone Moreira Ana Lucia de Araújo ramos Leslie Ecker Ferreira Angelo Alves de Mattos Cristiane Valle Tovo Lysandro Alsina Nader Juliene antonio ramos Edson Rondinelli Arnaldo de Jesus Dominici Christian Evangelista Garcia Mauro de Souza Leite Pinho carlos Eduardo Brando-Mello Cristiane Alves Villela-Nogueira Paulo Henrique Condeixa de Frana Departamento de Medicina Universidade da Regio de Joinville/UnivilleJoinville89219-719 Santa CatarinaBrazil Departamento de Clinica Médica e Cirurgia Geral Hospital Municipal So José Joinville89202-000 Santa CatarinaBrazil Departamento de Clínica Médica Servio de HepatologiaFaculdade de Medicina/Hospital Universitário Clementino Fraga Filho/Universidade Federal do Rio de Janeiro21941-913 Rio de JaneiroBrazil Servio de Gastroenterologia e Hepatologia Irmandade da Santa Casa de Misericórdia/ISCMPAPorto Alegre90020-090 Rio Grande do SulBrazil Servio de Endoscopia Universidade Federal de Pelotas/UFPelPelotas96010-610 Rio Grande do SulBrazil Instituto de Biofísica carlos Chagas Filho/UFRJ 21941-902 Rio de JaneiroBrazil Departamento de Gastroenterologia Hospital Universitário da Universidade Federal do Maranh o/UFMASo Luis65020-560 MaranhoBrazil Servio de Gastroenterologia Hospital Universitário Gaffrée Guinle/HUGG/UNIRIO20270-004 Rio de JaneiroBrazil

AIM:To analyze the role of rs12979860 and rs8099917polymorphisms in hepatitis C virus(HCV)genotype 1infection of ***:A total of 145 adult patients diagnosed with genotype 1 chronic hepatitis C(CHC)who had completed a 48-wk regimen of pegylated-interferonα-2a or-2b plus ribavirin combination therapy were recruited from six large urban healthcare centers and199 healthy blood donors(controls)from a single site between January 2010 and January *** on the patients’response to treatment was *** chain reaction-restriction fragment length polymorphism genotyping of the interleukin(IL)28B gene fragment encompassing the single nucleotide polymorphisms(SNPs)rs12979860(C/T)and rs8099917(T/G)was carried out for 79 of the CHC patients and 199 of the ***-directional amplicon sequencing of the two SNPs was carried out for the remaining 66 CHC ***:SNP rs12979860 genotyping was successful in 99.5%of the controls and 97.2%of the CHC patients,whereas the SNP rs8099917 genotyping was successful in 95.5%of the controls and 100%of the CHC *** genotype and allele distributions for both rs12979860 and rs8099917 were significantly different between the control and CHC patient groups,with significantly higher genotype frequencies of CC and TT in the controls(P=0.037 and 0.046,respectively)and of TT and GG in the CHC patients(P=0.0009and 0.0001,respectively).Analysis of the CHC patients who achieved sustained virological response(SVR)to treatment(n=55)indicated that the rs12979860 C allele and CC genotype were predictors of SVR(P=0.02).No significant correlation was found between rs8099917 genotypes and treatment response,but carriers of the T allele showed significantly higher rates of SVR(P=0.02).Linkage disequilibrium analysis of the group that achieved SVR showed a significant association between rs12979860 and rs8099917(P=0.07).CONCLUSION:The higher allele frequency of rs12979860 C and rs8099917 T observed in non-HCVinfec

关键词： Hepatitis C Interleukin 28B Single nucleotide polymorphisms Sustained virological response Brazil

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Acute fatty liver of pregnancy associated with severe acute pancreatitis:A case report

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World Journal of Hepatology 2014年第7期6卷 527-531页

作者： Cássio vieira de Oliveira Alecsro Moreira Julio P Baima Leticia de C Franzoni Talles B Lima Fabio da S Yamashiro Kunie Yabuki Rabelo Coelho Ligia Y Sassaki carlos antonio Caramori Ferno G Romeiro Giovanni F Silva Department of Internal Medicine Gastroenterology DivisionBotucatu Medical SchoolSao Paulo State University-UNESPBotucatuSao Paulo 01049-010Brazil Department of Pathology Botucatu Medical SchoolSao Paulo State University-UNESPBotucatuSao Paulo 01049-010Brazil

Acute fatty liver of pregnancy is a rare disease that affects women in the third trimester of pregnancy. Although infrequent, the disease can cause maternal mortality. The diagnosis is not always clear until the pregnancy is terminated, and significant complications, such as acute pancreatitis, can occur. Pancreatic involvement typically only occurs in severe cases after the development of hepatic and renal impairment. To date, little knowledge is available regarding how the disease causes pancreatitis. Treatment involves supportive measures and pregnancy interruption. In this report, we describe a case of a previously healthy 26-year-old woman at a gestational age of 27 wk and 6 d who was admitted with severe abdominal pain and vomiting. This case illustrates the clinical and laboratory overlap between acute fatty liver of pregnancy and pancreatitis, highlighting the difficulties in differentiating each disease. Furthermore, the hypothesis for this overlapping is presented, and the therapeutic options are discussed.

关键词： Acute fatty liver of pregnancy Severe acute pancreatitis Fulminant hepatic failure Liver disease in pregnancy

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Temporal trends in areas at risk for concomitant tuberculosis in a hyperendemic municipality in the Amazon region of Brazil

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Infectious Diseases of Poverty 2020年第4期9卷 162-162页

作者： Alexandre Tadashi Inomata Bruce Thais Zamboni Berra Felipe Lima dos Santos Yan Mathias Alves Ludmilla Leidianne Limirio Souza Antônio carlos vieira ramos Luiz Henrique Arroyo Juliane de Almeida Crispim Ione Carvalho Pinto Pedro Fredemir Palha Aline Aparecida Monroe Mellina Yamamura Regina Célia Fiorati Ana Carolina Scarpel Moncaio Dulce Maria de Oliveira Gomes Ricardo Alexandre Arcêncio Department of Maternal-Infant and Public Health Nursing University of São Paulo at Ribeirão Preto College of NursingRibeirão PretoSão PauloBrazil Department of Nursing Federal University of São CarlosSão CarlosSão PauloBrazil Department of Neurosciences and Behavioral Sciences Ribeirão Preto Medical School of the University of São PauloRibeirão PretoSão PauloBrazil Department of Nursing Federal University of CatalãoCatalãoGoiásBrazil Mathematics Department University ofÉvoraÉvoraPortugal

Background Although preventable and curable,tuberculosis(TB)still occurs in poor or developing countries,mainly in metropolitan regions of larger *** disease is a serious public health problem,and is directly linked to social *** analyzed temporal trend variations in areas at risk for concomitant TB,and characterized the clinical and epidemiological profiles of cases in a hyperendemic municipality in the Amazon region of *** This ecological study was performed in the municipality of Manaus,in northern *** population comprised cases with concomitant pulmonary and extrapulmonary TB,registered on the Notifiable Diseases Information System(SINAN),between January 1,2009 and December 31,*** risk cluster detection,spatial and spatiotemporal scanning statistical techniques were *** Spatial Variation in Temporal Trends(SVTT)approach was used to detect and infer clusters for significantly different time *** Between 2009 and 2018,873 concomitant TB cases were registered in *** using purely spatial scanning statistics,we identified two risk *** relative risk(RR)of the clusters was 2.21(95%confidence interval[CI]:1.57–2.88;P=0.0031)and 2.03(95%CI:1.58–2.58;P=0.0029).Using space-time scanning,we identified a risk cluster with an RR of 3.57(95%CI:2.84–4.41;P=0.014),between 2017 and *** SVTT analyses,three clusters with spatial variations were detected in the significant temporal trends:SVTT 1(P=0.042),SVTT 2(P=0.046)and SVTT 3(P=0.036).Conclusions In Brazil,several TB-determining factors such as race/color,gender,low educational level and low income overlap in needy urban areas and communities,demonstrating that it is unlikely to reach the goals,agreed and launched with the END TB Strategy within the deadlines of international agreements,if there is no reduction in existing inequities determinants and risk of illness in the country.

关键词： Tuberculosis Public health Epidemiology Spatial analysis Spatio-temporal analysis

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Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients

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World Journal of Gastroenterology 2008年第44期14卷 6824-6830页

作者： Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos Laboratório de Hipertenso Departamento de Fisiologia e BiofísicaICB-UFMGAv. Antonio Carlos6627Belo HorizonteMG31270-901Brazil Laboratório de Endocrinologia Departamento de Clínica MédicaFaculdade de Medicina-UFMGAv. Alfredo Balena190Belo HorizonteMG30130-100Brazil Departamento de Pediatria Faculdade de MedicinaUniversidade Federal de Minas Gerais (UFMG)Av. Alfredo Balena190Belo HorizonteMG30130-100Brazil

AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) ***:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio.

关键词： β-blockade Cirrhosis Renin angiotensinsystem Angiotensin-(1-7)

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Evidence of a J/ψΛstructure and observation of excited■^(-)states in the■b^(-)→J/ψΛK^(-) decay

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Science Bulletin 2021年第13期66卷 1278-1287,M0003页

作者： R.Aaij C.Abellán Beteta T.Ackernley B.Adeva M.Adinolfi H.Afsharnia C.A.Aidala S.Aiola Z.Ajaltouni S.Akar J.Albrecht F.Alessio M.Alexander A.Alfonso Albero Z.Aliouche G.Alkhazov P.Alvarez Cartelle S.Amato Y.Amhis L.An L.Anderlini A.Andreianov M.Andreotti F.Archilli A.Artamonov M.Artuso K.Arzymatov E.Aslanides M.Atzeni B.Audurier S.Bachmann M.Bachmayer J.J.Back S.Baker P.Baladron Rodriguez V.Balagura W.Baldini J.Baptista Leite R.J.Barlow S.Barsuk W.Barter M.Bartolini F.Baryshnikov J.M.Basels G.Bassi B.Batsukh A.Battig A.Bay M.Becker F.Bedeschi I.Bediaga A.Beiter V.Belavin S.Belin V.Bellee K.Belous I.Belov I.Belyaev G.Bencivenni E.Ben-Haim A.Berezhnoy *** D.Berninghoff H.C.Bernstein C.Bertella E.Bertholet A.Bertolin C.Betancourt F.Betti Ia.Bezshyiko S.Bhasin J.Bhom L.Bian M.S.Bieker S.Bifani P.Billoir M.Birch F.C.R.Bishop A.Bizzeti M.Bj┆rn M.P.Blago T.Blake F.Blanc S.Blusk D.Bobulska J.A.Boelhauve O.Boente Garcia T.Boettcher A.Boldyrev A.Bondar N.Bondar S.Borghi M.Borisyak M.Borsato J.T.Borsuk S.A.Bouchiba T.J.V.Bowcock A.Boyer C.Bozzi M.J.Bradley S.Braun A.Brea Rodriguez M.Brodski J.Brodzicka A.Brossa Gonzalo D.Brundu A.Buonaura C.Burr A.Bursche A.Butkevich J.S.Butter J.Buytaert W.Byczynski S.Cadeddu H.Cai R.Calabrese L.Calefice L.Calero Diaz S.Cali R.Calladine M.Calvi M.Calvo Gomez P.Camargo Magalhaes A.Camboni P.Campana A.F.Campoverde Quezada S.Capelli L.Capriotti A.Carbone G.Carboni R.Cardinale A.Cardini I.Carli P.Carniti L.Carus K.Carvalho Akiba A.Casais Vidal G.Casse M.Cattaneo G.Cavallero S.Celani J.Cerasoli A.J.Chadwick M.G.Chapman M.Charles Ph.Charpentier G.Chatzikonstantinidis C.A.Chavez Barajas M.Chefdeville C.Chen S.Chen A.Chernov S.-G.Chitic V.Chobanova S.Cholak M.Chrzaszcz A.Chubykin V.Chulikov P.Ciambrone M.F.Cicala X.Cid Vidal G.Ciezarek P.E.L.Clarke M.Clemencic H.V.Cliff J.Closier J.L.Cobbledick V.Coco J.A.B.Coelho J.Cogan E.Cogneras L.Cojocariu P.Collins T.Colombo L.Congedo A.Contu N.Cooke G.Coombs G.Corti C.M.Costa Sobral B.Couturier D.C.Craik J.Crkovská M.Cruz Torres R.Currie C.L.Da Silva E.Dall’ Centro Brasileiro de Pesquisas Físicas(CBPF) Rio de JaneiroBrazil Universidade Federal do Rio de Janeiro(UFRJ) Rio de JaneiroBrazil Center for High Energy Physics Tsinghua UniversityBeijingChina School of Physics State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijingChina University of Chinese Academy of Sciences BeijingChina Institute Of High Energy Physics(IHEP) BeijingChina Institute of Particle Physics Central China Normal UniversityWuhanHubeiChina Univ.Grenoble Alpes Univ.Savoie Mont BlancCNRSIN2P3-LAPPAnnecyFrance UniversitéClermont Auvergne CNRS/IN2P3LPCClermont-FerrandFrance Aix Marseille Univ CNRS/IN2P3CPPMMarseilleFrance UniversitéParis-Saclay CNRS/IN2P3IJCLabOrsayFrance Laboratoire Leprince-ringuet(llr) PalaiseauFrance LPNHE Sorbonne UniversitéParis Diderot Sorbonne Paris CitéCNRS/IN2P3ParisFrance I.Physikalisches Institut RWTH Aachen UniversityAachenGermany Fakultät Physik Technische Universität DortmundDortmundGermany Max-Planck-Institut für Kernphysik(MPIK) HeidelbergGermany Physikalisches Institut Ruprecht-Karls-Universität HeidelbergHeidelbergGermany School of Physics University College DublinDublinIreland INFN Sezione di Bari BariItaly INFN Sezione di Bologna BolognaItaly INFN Sezione di Ferrara FerraraItaly INFN Sezione di Firenze FirenzeItaly INFN Laboratori Nazionali di Frascati FrascatiItaly INFN Sezione di Genova GenovaItaly INFN Sezione di Milano-Bicocca MilanoItaly INFN Sezione di Milano MilanoItaly INFN Sezione di Cagliari MonserratoItaly Universita degli Studi di Padova Universita e INFNPadovaPadovaItaly INFN Sezione di Pisa PisaItaly INFN Sezione di Roma Tor Vergata RomaItaly INFN Sezione di Roma La Sapienza RomaItaly Nikhef National Institute for Subatomic Physics AmsterdamNetherlands Nikhef National Institute for Subatomic Physics and VU University Amsterdam AmsterdamNetherlands Henryk Niewodniczanski Institute of Nuclear Physics Polish Academy of Sciences KrakówPoland AGH-University of Science and Techno

First evidence of a structure in the J/ψΛinvariant mass distribution is obtained from an amplitude analysis of■b^(-)J/ψΛK^(-)*** observed structure is consistent with being due to a charmonium pentaquark with strangeness with a significance of 3.1r including systematic uncertainties and lookelsewhere *** mass and width are determined to be 4458:8±2:9t4:7-1:1 MeV and 17:3±6:5t8:0-5:7 MeV,respectively,where the quoted uncertainties are statistical and *** structure is also consistent with being due to two *** addition,the narrow excited■^(-)states,N■(1690)and■(1820),are seen for the first time in a■b^(-)decay,and their masses and widths are measured with improved *** analysis is performed using pp collision data corresponding to a total integrated luminosity of 9 fb^(-1),collected with the LHCb experiment at centre-of-mass energies of 7,8 and 13 TeV.

关键词： QCD Exotics Pentaquark Spectroscopy Quarkonium Particle and resonance production

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