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石化译文 1995年第4期 22-27页

作者： gallo,R 姜作勤

Balloon aortic valvuloplasty as a bridge-to-decision in high risk patients with aortic stenosis： a new paradigm for the heart team decision making

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Journal of Geriatric Cardiology 2016年第6期13卷 475-482页

作者： Francesco Saia Carolina Moretti Gianni Dall'Ara Cristina Ciuca Nevio Taglieri Alessandra Berardini Pamela gallo Marina Cannizzo Matteo Chiarabelli Niccolo Ramponi Linda Taffani Maria Letizia Bacchi-Reggiani Cinzia Marrozzini Claudio Rapezzi Antonio Marzocchi Cardio-Thoraco-Vascular Department University Hospital of Bologna Bologna Italy

Background Whilst the majority of the patients with severe aortic stenosis can be directly addressed to surgical aortic valve replace- ment （AVR） or transcatheter aortic valve implantation （TAVI）, in some instances additional information may be needed to complete the diagnostic workout. We evaluated the role of balloon aortic valvuloplasty （BAV） as a bridge-to-decision （BTD） in selected high-risk patients. Methods Between 2007 and 2012, the heart team in our Institution required BTD BAV in 202 patients. Very low left ventricular ejection fraction, mitral regurgitation grade 〉 3, frailty, hemodynamic instability, serious comorbidity, or a combination of these factors were the main drivers for this strategy. We evaluated how BAV influenced the final treatment strategy in the whole patient group and in each specific subgroup. Results Mean logistic European System for Cardiac Operative Risk Evaluation （EuroSCORE） was 23.5%±15.3%, age 81 ± 7 years. In-hospital mortality was 4.5%, cerebrovascular accident 1% and overall vascular complications 4% （0.5% major; 3.5% minor）. Of the 193 patients with BTD BAV who survived and received a second heart team evaluation, 72.6% were finally deemed eligible for definitive treatment （25.4% for AVR; 47.2% for TAVI）： 96.7% of patients with left ventricular ejection fraction recovery; 70.5% of patients with mitral regurgitation reduction; 75.7% of patients who underwent BAV in clinical hemodynamic instability; 69.2% of frail patients and 68% of patients who presented serious comorbidities. Conclusions Balloon aortic valvuloplasty can be considered as bridge-to- decision in high-risk patients with severe aortic stenosis who cannot be immediate candidates for definitive transcatheter or surgical treatment.

关键词： Aortic valve replacement Aortic valve stenosis Heart team Mitral valve regurgitation Transcatheter aortic valve implantation

Nanofiber matrix formulations for the delivery of Exendin-4 for tendon regeneration: In vitro and in vivo assessment

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Bioactive Materials 2023年第7期25卷 42-60页

作者： Sama Abdulmalik Jack gallo Jonathan Nip Sara Katebifar Michael Arul Amir Lebaschi Lucas N.Munch Jenna M.Bartly Shilpa Choudhary Ivo Kalajzic Yeshavanth Kumar Banasavadi-Siddegowdae Syam P.Nukavarapu Sangamesh G.Kumbar Department of Orthopedic Surgery University of Connecticut HealthFarmingtonCTUSA Department of Biomedical Engineering University of ConnecticutStorrsCTUSA Department of Materials Science and Engineering University of ConnecticutStorrsCTUSA Department of Physiology and Neurobiology University of ConnecticutStorrsCTUSA Department of Immunology Center on AgingUniversity of Connecticut HealthFarmingtonCTUSA Department of Reconstructive Sciences University of Connecticut HealthFarmingtonCTUSA Surgical Neurology Branch National Institute of Neurological Disorders and StrokeNational Institutes of HealthBethesdaMDUSA

Tendon and ligament injuries are the most common musculoskeletal injuries,which not only impact the quality of life but result in a massive economic *** interventions for tendon/ligament injuries utilize biological and/or engineered grafts to reconstruct damaged tissue,but these have *** matrices confer superior physicochemical properties over biological grafts but lack desirable bioactivity to promote tissue *** incorporating drugs can enhance bioactivity,large matrix surface areas and hydrophobicity can lead to uncontrolled burst release and/or incomplete release due to *** overcome these limitations,we evaluated the delivery of a peptide growth factor(exendin-4;Ex-4)using an enhanced nanofiber matrix in a tendon injury *** overcome drug surface binding due to matrix hydrophobicity of poly(caprolactone)(PCL)-which would be expected to enhance cell-material interactions-we blended PCL and cellulose acetate(CA)and electrospun nanofiber matrices with fiber diameters ranging from 600 to 1000 *** avoid burst release and protect the drug,we encapsulated Ex-4 in the open lumen of halloysite nanotubes(HNTs),sealed the HNT tube endings with a polymer blend,and mixed Ex-4-loaded HNTs into the polymer mixture before *** reduced burst release from~75%to~40%,but did not alter matrix morphology,fiber diameter,or tensile *** evaluated the bioactivity of the Ex-4 nanofiber formulation by culturing human mesenchymal stem cells(hMSCs)on matrix surfaces for 21 days and measuring tenogenic differentiation,compared with nanofiber matrices in basal media ***,we observed that Ex-4 nanofiber matrices accelerated the hMSC proliferation rate and elevated levels of sulfated glycosaminoglycan,tendon-related genes(Scx,Mkx,and Tnmd),and ECM-related genes(Col-Ⅰ,Col-Ⅲ,and Dcn),compared to *** then assessed the safety and efficacy of Ex-4 nanofiber matrices in a full-thickness rat Achilles tendon

关键词： Nanofiber matrix formulation Protein delivery Soft tissue regeneration Halloysite nanotubes

Could JC virus provoke metastasis in colon cancer?

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World Journal of Gastroenterology 2014年第42期20卷 15745-15749页

作者： Emanuele Sinagra Dario Raimondo Elena gallo Mario Stella Mario Cottone Ambrogio Orlando Francesca Rossi Emanuele Orlando Marco Messina Giovanni Tomasello Attilio Ignazio Lo Monte Ennio La Rocca Aroldo Gabriele Rizzo Gastroenterology and Endoscopy Unit Fondazione Istituto San Raffaele-G Giglio Contrada Pietra Pollastra Pisciotto course in Surgical Biotechnology and Regenerative Medicine University of Palermo Euro-Mediterranean Institute of Science and Technology (IEMEST) Unit of Pathology Ospedali Riuniti Villa Sofia - Cervello University of Palermo DIBIMIS Unit of Internal Medicine Ospedali Riuniti Villa Sofia - Cervello University of Palermo Oncology Unit Fondazione Istituto San Raffaele-G Giglio Contrada Pietra Pollastra Pisciotto Department of Surgical and Oncological Disciplines School of Medicine University of Palermo Unità Operativa di Medicina interna e trapiantologia Ospedale San Raffaele

AIM: To evaluate the prevalence of John Cunningham virus(JC virus) in a small cohort of patients with colon cancer and to assess its presence in hepatic ***: Nineteen consecutive patients with histologically diagnosed colon cancer were included in our study, together with ten subjects affected by histologically and serologically diagnosed hepatitis C virus infection. In the patients included in the colon cancer group, JC virus was searched for in the surgical specimen; in the control group, JC virus was searched for in the hepatic biopsy. The difference in the prevalence of JC virus in the hepatic biopsy between the two groups was assessed through the χ2 ***: Four out of 19 patients with colon cancer had a positive polymerase chain reaction(PCR) test for JC virus, and four had liver metastasis. Among the patients with liver metastasis, three out of four had a positive PCR test for JC virus in the surgical specimen and in the liver biopsy; the only patient with liver metastasis with a negative test for JC virus also presented a negative test for JC virus in the surgical specimen. In the control group of patients with hepatitis C infection, none of the ten patients presented JC virus infection in the hepatic biopsy. The difference between the two groups regarding JC virus infection was statistically significant(χ2 = 9.55, P = 0.002).CONCLUSION: JC virus may play a broader role than previously thought, and may be mechanistically involved in the late stages of these tumors.

关键词： John Cunningham virus Colon cancer Me-tastasis

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飞鱼导弹的真实部件仿真

飞航导弹 1990年第5期 10-16,40页

作者： Christiane Renon Guy le gallo Gerard Selince 郭福涛

本文主要介绍对首批生产的1500枚飞鱼反舰导弹系列(MM38、MM40、AM39、SM39)进行仿真所取得的结果。首先介绍法国宇航公司战术导弹分公司的仿真设备,特别是设在法国布尔日附近的苏巴特拉的设备,然后展示所起作用——从计划开始执行直到... 详细信息

本文主要介绍对首批生产的1500枚飞鱼反舰导弹系列(MM38、MM40、AM39、SM39)进行仿真所取得的结果。首先介绍法国宇航公司战术导弹分公司的仿真设备,特别是设在法国布尔日附近的苏巴特拉的设备,然后展示所起作用——从计划开始执行直到生产出导弹的整个研制阶段仿真所起的作用。叙述的重点是生产阶段运用仿真的好处:用来提高导弹质量,获得对开发新型号的有益知识并作为生产期间一种质量保证方法。

关键词：反舰导弹仿真技术飞鱼导弹

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是什么让乔布斯成为“乔布斯”?

英语沙龙（高中） 2011年第11期 8-9页

作者： Carmine gallo 不详

在这个世界上，能够重塑一个行业的人寥寥无几，但乔布斯却彻底变革了电脑、通讯、音乐等多个行业。虽然他已离开了这个世界，但我们应该问问自己：他是如何做到这一切的？更为重要的是，我们应该如何向他学习．以释放我们身体里的“乔... 详细信息

在这个世界上，能够重塑一个行业的人寥寥无几，但乔布斯却彻底变革了电脑、通讯、音乐等多个行业。虽然他已离开了这个世界，但我们应该问问自己：他是如何做到这一切的？更为重要的是，我们应该如何向他学习．以释放我们身体里的“乔布斯”，从而推动我们的公司、我们的事业以及这个世界继续向前发展？

关键词：乔布斯世界行业公司

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警察故事

疯狂英语（阅读版） 2004年第9期 54-61页

作者： Gina gallo 韩英

警员的生活到底是怎样的?这是我们警务人员不愿意谈及的一个话题。尽管人人都想知道,可真正了解实情的人却不多。因为除非你自己当过警察,要不然你就永远无法体验当警察的酸甜苦辣滋味。很多人信誓旦旦地说他们了解警察,先是从一名警官... 详细信息

警员的生活到底是怎样的?这是我们警务人员不愿意谈及的一个话题。尽管人人都想知道,可真正了解实情的人却不多。因为除非你自己当过警察,要不然你就永远无法体验当警察的酸甜苦辣滋味。很多人信誓旦旦地说他们了解警察,先是从一名警官的家庭讲起,然后牵扯出一长串的故事,最后扯到好莱坞的警匪电影,好莱坞的制片人和剧作家们就这样煞费苦心地炮制又一出“真实的”警察故事。可事实上,要了解真实的警察故事,你就必须宣誓成为一名代表正义的警官,并佩带上警徽参与日常的巡逻值勤。

关键词：警察好莱坞警务人员警官咖啡传呼器制片人剧作家家庭 READE

Stroke and Covid-19: The Experience of the Ziguinchor/Senegal Epidemic Treatment Center

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Neuroscience & Medicine 2022年第3期13卷 103-110页

作者： Khalifa Ababacar Mbaye Kalilou Diallo Rokhaya Diagne Moustapha Ndiaye Amadou gallo Diop Noël Magloire Manga Ibrahima Pierre Ndiaye Neurology Department Fann Teaching Hospital Dakar Senegal Infectious Diseases Department Peace Hospital Ziguinchor Ziguinchor Senegal

Introduction: SARS-CoV-2 infection seems to have a brain tropism involving several pathophysiological mechanisms. The objective of our work was to study the epidemiological, clinical, paraclinical and evolutionary aspects of stroke patients following SARS-CoV-2 infection. Methodology: This was a retrospective descriptive and analytical study from 26 March 2020 to 30 September 2021, which took place at the Ziguinchor epidemic treatment center. All patients infected with SARS-CoV-2 confirmed by RT-PCR with clinical signs suggestive of stroke and confirmed by brain CT scan were included in our study. Patients with incomplete or unexploitable records were excluded. Results: Twenty-four patients were collected out of a total of 186 severe cases, a prevalence of 12.90%. All patients had an ischemic stroke. The mean age was 69 ± 6 years with extremes of 58 and 84 years. The sex ratio (M/F) was 1.2. Diabetes and hypertension were co-morbidities in 87.50% and 25% of cases respectively. Clinical signs were dominated by a hemi-corporal deficit (87.5%) and dyspnea (75%). All patients were on anticoagulation and corticosteroids. The evolution was favourable in 62.5% of patients against 37.5% of death. Conclusion: SARS-CoV-2 infection is responsible for numerous neurovascular complications and this risk increases with the presence of diabetes, arterial hypertension and emboligenic heart disease. Corticosteroid therapy and anticoagulation have allowed us to improve the prognosis of patients.

关键词： Covid-19 Stroke Ziguinchor Senegal

应用 NOAA AVHRR 作大面积作物监测——估测玉米吐丝期

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气象科技 1991年第2期19卷 85-88,98页

作者： K.P.gallo T.K.Flesch 谭凯琰卫星研究实验室NOAA/NESDIS Purdue大学农学系

吐丝是玉米生长发育中的重要环节,该阶段的天气条件会危及作物的最终产量。掌握吐丝出现的时间及同期的气象条件对监测作物产量是重要的。在美国,根据田间观测可进行作物的发育期估测,然而,对于其它地区,这些资料则不易得到。因此,一种... 详细信息

吐丝是玉米生长发育中的重要环节,该阶段的天气条件会危及作物的最终产量。掌握吐丝出现的时间及同期的气象条件对监测作物产量是重要的。在美国,根据田间观测可进行作物的发育期估测,然而,对于其它地区,这些资料则不易得到。因此,一种应用卫星监测吐丝期的方法被提出,并与基于地面的估测进行了比较。在地面估测吐丝期的一周内,由 NOAA AVHRR 可见光和近红外的周合成资料计算得出几种植被指数,并用它们来估测大面积吐丝出现期。

关键词：吐丝期 NOAA AVHRR 玉米带玉米生长发育田间观测最终产量出现期植被指数天气条件气象条件

Active surveillance of adverse drug reactions in children in five Italian paediatric wards

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Open Journal of Pediatrics 2012年第2期2卷 111-117页

作者： Mariapina gallo Antonio Clavenna Maurizio Bonati Paolo Siani Antonio Irpino Francesco Rossi Annalisa Capuano Department of European and Mediterranean Studies Faculty of Political Studies and Higher European Education Jean Monnet Second University of Naples Naples Italy Department of Experimental Medicine Section of Pharmacology “Leonardo Donatelli” Center of Pharmacosurveillance and Phar-macoepidemiology Faculty of Medicine and Surgery Second University of Naples Naples Italy Laboratory for Mother and Child Health Department of Public Health Mario Negri Institute for Pharmacological Research Milan Italy Pediatric Department AORN A. Santobono-Pausillipon Hospital Naples Italy

Adverse drug reactions (ADRs) are an important clinical problem and contribute significantly to mortality and morbidity. Scant data on the safety of drug use in children are usually available at the time of marketing authorization, due to the limited number of trials performed in the paediatric population. Few studies monitored the incidence of ADRs in Italian hospitalized children, that cannot be compared for methodological reasons. A 6-month prospective observational study was, therefore, conducted on the paediatric wards of five hospitals in the Campania Region, Italy. Data were collected on all patients admitted to the wards during the study period through a structured questionnaire administered to the mothers and through a hospital chart review. Of the 752 patients enrolled, 86.2% were exposed to one or more drugs during hospitalization. The therapeutic class most prescribed was systemic antibacterial agents (47%). Six ADRs occurred during hospitalization (incidence 0.9%;95% CI 0.2% - 1.7%). In addition, one child was admitted to a hospital for an ADR. Five out of seven ADRs occurred in girls. The skin was the most affected organ. The medications implicated were amoxicillin, acyclovir, ibuprofen, ceftriaxone, paracetamol, and ranitidine. According to the Naranjo probability criteria, six ADRs were probably, and one possibly, related to the suspected drug. In conclusion, this study reveals that ADRs may be under-reported in children hospitalized in the Campania Region. Consequently, healthcare personnel should be alert to the possibility of ADRs. More accurate reporting of ADRs in children would result in safer use of drugs in such patients.

关键词： Child Prospective Studies Drug Therapy/Adverse Effects Adverse Drug ReactionReporting System Hospital